New model acts as search engine for large databases of pathology images, helping to identify rare diseases and determine patients likely to respond to similar therapies.
Protocol eligibility criteria often had language that could be used to exclude people with cognitive, visual, hearing, mobility, and other disabilities, without documented justification
Military service members who have returned from theaters of war are at increased risk of mental health problems.
Dietary choices and their consequences may certainly influence cognitive function.
Frailty is defined as reduced physiological reserve and ability to cope with acute stresses. Up to half of adults over the age of 85 live with frailty and thus, preventative measures are greatly needed.
Over recent decades, more and more adults under the age of 50 are developing cancer.
A clinical trial of patients with COVID-19 led by investigators at the TIMI Study Group at Brigham and Women’s Hospital and the Critical Care Cardiology Trials Network (CCCTN) has found that full-dose anticoagulation lowers the risk of blood clotting complications compared with standard-dose prophylactic anticoagulation.
Throughout the pandemic, waves of COVID-19 cases have had corresponding waves of excess mortality — deaths that go above and beyond the expected number for that time of year. But in Massachusetts, where more than 80 percent of the population is fully vaccinated, researchers found that during the 18 weeks from Feb. 27 to June 26, 2022, there was no excess mortality in the state, despite waves of COVID cases and hospitalizations.
Heart failure is a common and devastating disorder for which there is no cure. Many cardiomyopathies —conditions that make it difficult for the heart to pump blood such as dilated cardiomyopathy (DCM) and arrhythmogenic cardiomyopathy (ACM) — can lead to heart failure, but treatments for patients with heart failure do not take these distinct conditions into account.
Although vitamin D supplements are widely prescribed and used to benefit bone health, definitive data on whether these supplements reduce fractures in the general population have been inconsistent.
Children who were born preterm are at heightened risk of lower academic achievement in math, reading and other skills and are also at greater risk for attention-deficit/hyperactivity disorder (ADHD).
Researchers have uncovered a new function for alpha-synuclein, a well-known protein marker of Parkinson’s, with relevance toward treatment for the disease
Inside brain cells, errors in DNA can accumulate as we age. But in patients with Alzheimer’s disease, these errors — known as somatic mutations — may build up at a faster rate.
A person’s risk of developing diseases such as type 2 diabetes or breast cancer may be influenced by thousands of genetic differences.
Daytime napping is common among older adults. The longitudinal relationship between daytime napping and cognitive aging, however, is unknown.
Large-scale randomized trial found signs of preventive cardiovascular effects for cocoa flavanols, including a 27 percent reduction in the secondary endpoint of cardiovascular death
Any fever or chills? Cough? Shortness of breath? Answering these questions and others has become a familiar part of daily life during the pandemic.
The widespread use of masks during the COVID-19 pandemic has posed numerous communication barriers, muffling speech and impeding lip-reading.
To grow and spread, cancer cells must evade the immune system. Investigators from Brigham and Women’s Hospital and MIT used the power of nanotechnology to discover a new way that cancer can disarm its would-be cellular attackers by extending out nanoscale tentacles that can reach into an immune cell and pull out its powerpack.
Scientists have long suggested that getting enough sleep at night is vital to staying healthy.
Researchers estimate that up to $101 billion in health care spending is wasted each year due to over-treatment or the delivery of “low-value care.”
A study led by researchers from Brigham and Women’s Hospital has established a new resource for exploring and understanding Alzheimer’s disease (AD) on an individualized level.
A research team from Brigham and Women’s Hospital has found that delivering acute care at home for non-COVID patients freed up substantial inpatient capacity during the COVID-19 surge last spring.
As the SARS-CoV-2 virus that causes COVID-19 continues to evolve, immunologists and infectious diseases experts are eager to know whether new variants are resistant to the human antibodies that recognized initial versions of the virus.
More than 80 percent of people around the world consider themselves to be religious or spiritual. But research on the neuroscience of spirituality and religiosity has been sparse.
A high intake of chocolate during the morning hours could help to burn fat and reduce blood glucose levels.
Asthma attacks account for almost 50 percent of the cost of asthma care which totals $80 billion each year in the United States
Chronic pain is among the most common chronic conditions in the United States, but estimates of its prevalence and impact vary widely.
Eczema, or atopic dermatitis (AD), is sometimes called "the itch that rashes." Often, the itch begins before the rash appears, and, in many cases, the itchiness of the skin condition never really goes away.
Sleep and health are inextricably connected.
Among infectious diseases that have caused pandemics and epidemics, smallpox stands out as a success story. Smallpox vaccination led to the disease's eradication in the twentieth century.
Use of the delivery system in mouse models results in unprecedented siRNA penetration across the intact blood brain barrier
The Mediterranean (MED) diet -- rich in olive oil, fruits, vegetables, legumes, nuts and seeds -- is a recommended way to reduce the risk of heart disease, type 2 diabetes and other adverse health outcomes.
For many years, investigators have been trying to pin down the tantalizing connection between vitamin D and cancer.
Predicting the course of a COVID-19 patient's disease after hospital admission is essential to improving treatment.
One of the pressing questions about COVID-19 remains: How long does immunity last? One key indicator of immunity is the presence of virus-specific antibodies.
While older age is widely recognized as a risk factor for increased morbidity and mortality due to COVID-19, younger patients have received less attention as a population vulnerable to adverse clinical outcomes.
A tool designed to detect viral history in a drop of blood has gotten an upgrade in the age of COVID-19.
Losing your balance and falling does not just happen during icy Boston winters.
During the COVID-19 pandemic, social distancing and stay-at-home orders have been enacted throughout the world to stop disease transmission and keep people safe.
We may not think about it often, but our gut is home to a complex ecosystem of microorganisms that play a critical role in how we function.
Using information from a national database, investigators took an evidence-based approach to defining the lower limit of pulmonary vascular resistance
In March of 2020, Mass General Brigham implemented a new policy: everyone working at the hospitals would be required to wear a surgical mask.
A new study by investigators from Brigham and Women's Hospital examines changes in prescription patterns in the United States during the COVID-19 pandemic.
Patients with type 2 diabetes who have high levels of blood sugar are at greater risk of serious complications such as chronic kidney disease, heart disease and blindness.
In the largest study of skin cancer rates among gay, lesbian or bisexual individuals, investigators from Brigham and Women's Hospital report important differences in skin cancer prevalence among sexual minorities.
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