The hearts of newborn piglets can almost completely heal themselves after experimental heart attacks, the first time this ability to regrow heart muscle has been shown in large mammals. This regenerative capacity disappears by day three after birth, researchers report in the journal Circulation.
Reduced levels of a chaperone protein might have implications for the development of Parkinson’s disease and Lewy body dementia, according to new research from UAB. Chaperone protein 14-3-3 could lead to misfolding and spread of alpha-synuclein.
Newborn granule cells show high excitability that disappears as the cells mature. Now University of Alabama at Birmingham researchers have described key roles for G protein-mediated signaling and the late maturation of an ion channel during the differentiation of granule cells.
Researchers have now described an underlying mechanism that reprograms the hearts of patients with ischemic cardiomyopathy, a process that differs from patients with other forms of heart failure. This points the way toward future personalized care.
Staying hydrated while in the heat is almost common sense, but can too much water be a bad thing?
Researchers have found an important contributor to heart pathology caused by the cancer drug doxorubicin — disruption of metabolism that controls immune responses in the spleen and heart. This allows chronic, non-resolving inflammation that leads to advanced heart failure.
A new enhanced recovery after surgery process — also known as ERAS — has been developed and implemented at the University of Alabama at Birmingham to help enhance a mother’s recovery after a cesarean delivery, one of the most common surgeries performed in the United States.
Michelle Fanucchi, Ph.D., is a public health expert who specializes in air and water pollution.
With the start of the school year just around the corner, it is easy to overlook one of the most important things on any back-to-school checklist — making sure your child is vaccinated.
Artist-in-residence Elizabeth Vander Kamp laughs with a patient during an Arts in Medicine visit.Many hospitalized patients, especially older adults, are at risk of developing delirium, a risk that is increased by the presence of cognitive, functional, visual or hearing impairment or depression. Performing arts programs that include storytelling and poetry may be beneficial in lowering that risk, suggests a study from the University of Alabama at Birmingham.
High-tech medicine and human kindness combine in UAB’s ongoing kidney chain, a series of transplant surgeries that have given 101 people a new lease on life.
While blood and marrow transplants can save the life of a pediatric cancer patient, research out of the University of Alabama at Birmingham found that those patients may be at an increased risk of premature death even years or decades after the procedure as compared with the general population.
Preliminary results of the SPRINT MIND trial found that lowering one’s systolic blood pressure to 120 mm Hg reduces the risk of mild cognitive impairment and dementia.
Published in Addiction, a new paper lays out some of the factors that lead policymakers to look for easy answers to complex problems related to opioid addiction.
Experts have updated recommendations for the use of antiretroviral drugs in the treatment and prevention of HIV infection.
When a mutation for mitochondrial dysfunction is induced in a mouse model, the mouse develops wrinkled skin and extensive hair loss in a matter of weeks. This is reversed to normal appearance when mitochondrial function is restored by turning off the gene responsible for mitochondrial dysfunction.
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