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Released: 15-Mar-2010 3:00 PM EDT
3-D Cell Culture: Making Cells Feel Right at Home
University of Texas MD Anderson Cancer Center

The film "Avatar" isn't the only 3-D blockbuster making a splash this winter. A team of Houston scientists this week unveiled a new technique for growing 3-D cell cultures, a technological leap from the flat petri dish that could save millions of dollars in drug-testing costs. The research is reported in Nature Nanotechnology.

Released: 11-Mar-2010 4:30 PM EST
I Have Colon Polyps: Now What?
University of Texas MD Anderson Cancer Center

Experts at The University of Texas M. D. Anderson Cancer Center encourage people to review their polyp report.

5-Mar-2010 10:55 AM EST
Most Early Stage Breast Cancer Patients May Not Need Radiation After Mastectomy
University of Texas MD Anderson Cancer Center

Breast cancer patients with early stage disease that has spread to only one lymph node may not benefit from radiation after mastectomy, because of the low present-day risk of recurrence following modern surgery and systemic therapy, a finding that could one day change the course of treatment for thousands of women diagnosed each year, according to researchers at The University of Texas M. D. Anderson Cancer.

3-Mar-2010 3:00 PM EST
Costly Tests May Not Help Detect Bladder Cancer Recurrence
University of Texas MD Anderson Cancer Center

In a new study from The University of Texas M. D. Anderson Cancer Center, researchers found that cystoscopy, the standard for screening for recurrence of early-stage bladder cancer, is a cost-effective method of detecting tumors.

Released: 1-Mar-2010 3:35 PM EST
Researchers Develop Tool to Measure Severity of Chronic Graft-Versus-Host Disease Symptoms
University of Texas MD Anderson Cancer Center

Researchers from The University of Texas M. D. Anderson Cancer Center have developed a new assessment tool to measure the severity of symptoms that can complicate stem cell transplantation. The tool assesses symptoms resulting from chronic graft-versus-host disease (cGVHD), and was presented with supporting research at the 2010 Bone and Marrow Transplant Tandem Meeting.

23-Feb-2010 4:50 PM EST
Contralateral Prophylactic Mastectomy Associated with Survival in Select Group of Breast Cancer Patients
University of Texas MD Anderson Cancer Center

Contralateral prophylactic mastectomy (CPM), a preventive procedure to remove the unaffected breast in patients with disease in one breast, may only offer a survival benefit to breast cancer patients age 50 and younger, who have early-stage disease and are estrogen receptor (ER) negative, according to researchers at The University of Texas M. D. Anderson Cancer Center.

Released: 25-Feb-2010 10:55 AM EST
New Strategy Develops Two Prototype Drugs Against Cancer, Retinal Diseases
University of Texas MD Anderson Cancer Center

A comprehensive screening of peptide targeting agents and follow-up analysis produce two small-molecule drugs that attack EGFR and VEGFR pathways in novel ways.

Released: 23-Feb-2010 2:40 PM EST
Miami Symposium Honors Fidler for Metastasis Research
University of Texas MD Anderson Cancer Center

Isaiah J. Fidler, D.V.M, Ph.D., a pioneer in understanding how cancer spreads to other organs and then taps its new environment to thrive and grow, has received the Lifetime Achievement Award from Nature Publishing at the 2010 Miami Winter Symposium - Targeting Cancer Invasion and Metastasis.

Released: 17-Feb-2010 9:00 PM EST
Researchers Discover Second Protective Role for Tumor-Suppressor
University of Texas MD Anderson Cancer Center

ATM, a protein that reacts to DNA damage by ordering repairs or the suicide of the defective cell, plays a similar, previously unknown role in response to oxidative damage outside of the nucleus, researchers report this week in the online version of the Proceedings of the National Academy of Sciences.

4-Feb-2010 12:45 PM EST
Low Forms of Cyclin E Reduce Breast Cancer Drug's Effectiveness
University of Texas MD Anderson Cancer Center

M. D. Anderson researchers find better way to predict prognosis in patients treated with aromatase inhibitors; research also suggests a potential means of circumventing drug resistance.

Released: 8-Feb-2010 10:45 AM EST
M. D. Anderson’s Seven-Day Exercise Plan
University of Texas MD Anderson Cancer Center

Being active for at least 30 minutes every day reduces your risk of developing some types of cancer. Fitness experts at The University of Texas M. D. Anderson Cancer Center have designed an exclusive exercise plan based on this evidence that will fit into almost anyone’s lifestyle.

Released: 27-Jan-2010 3:20 PM EST
Researchers Find Leukemia Cells Metabolize Fat to Avoid Cell Death
University of Texas MD Anderson Cancer Center

Leukemia cells, like most cancers, are addicted to glucose to generate their energy, but new research shows for the first time that these cells also rely on fatty acid metabolism to grow and to evade cell death.

Released: 15-Jan-2010 12:10 PM EST
Cancer Stem Cells Suppress Immune Response Against Brain Tumor
University of Texas MD Anderson Cancer Center

Cancer-initiating cells that launch glioblastoma multiforme, the most lethal type of brain tumor, also suppress an immune system attack on the disease, scientists from The University of Texas M. D. Anderson Cancer Center report in a paper featured on the cover of the Jan. 15 issue of Clinical Cancer Research.

Released: 12-Jan-2010 3:45 PM EST
The HPV Vaccine: What Have We Learned?
University of Texas MD Anderson Cancer Center

Expert at The University of Texas M. D. Anderson Cancer Center provide insight to parents based on what we've learned about about the HPV vaccine in the past four years.

Released: 12-Jan-2010 2:45 PM EST
Major Grant Amplifies Efforts of Childhood Anti-Obesity Alliance
University of Texas MD Anderson Cancer Center

CAN DO Houston (Children and Neighbors Defeating Obesity) will expand its community-based efforts with a $360,000 grant from the Robert Wood Johnson Foundation’s “Healthy Kids, Healthy Communities” initiative.

11-Jan-2010 3:40 PM EST
Growth Factor Hit by Cancer Drugs also Protects Heart
University of Texas MD Anderson Cancer Center

A growth factor that is a common target of cancer drugs also plays an important role in the heart's response to stress, researchers at The University of Texas M. D. Anderson Cancer Center report online this week in the Journal of Clinical Investigation.

Released: 7-Jan-2010 10:30 AM EST
Arap, Pasqualini Earn O'Donnell Award from Texas Academy
University of Texas MD Anderson Cancer Center

Two scientists who discovered that blood vessels supplying different organs and tissues have unique molecular signatures which may be exploited to develop highly targeted therapies will receive the 2010 Edith and Peter O'Donnell Award in Medicine from The Academy of Medicine, Engineering and Science of Texas.

9-Dec-2009 8:40 PM EST
Racial Disparities Exist in Radiation Therapy Rates for Early Stage Breast Cancer
University of Texas MD Anderson Cancer Center

Black women are less likely than white women to receive radiation therapy after a lumpectomy, the standard of care for early stage breast cancer, according to a new study by researchers at The University of Texas M. D. Anderson Cancer Center.

10-Dec-2009 2:00 PM EST
Study Questions True Favorability of Rare Breast Cancer Type
University of Texas MD Anderson Cancer Center

In a large review of breast cancer patients with mucinous carcinoma, researchers at The University of Texas M. D. Anderson Cancer Center have identified an association between this rare type of breast cancer long-associated with a favorable prognosis and multiple tumors undetected by mammography or ultrasound.

9-Dec-2009 3:40 PM EST
Novel Detection Method Unmasks Circulating Breast Cancer Cells
University of Texas MD Anderson Cancer Center

Circulating metastatic breast cancer cells can lose their epithelial receptors, a process that enables them to travel through the bloodstream undetected, according to research from The University of Texas M. D. Anderson Cancer Center.

Released: 9-Dec-2009 10:00 AM EST
Sonic Hedgehog Pathway Variations Linked to Recurrence, Survival and Response to Therapy of Non-Invasive Bladder Cancer Patients
University of Texas MD Anderson Cancer Center

Genetic variations in the Sonic Hedgehog pathway increase the likelihood of recurrence, reduce survival time and limit response to therapy for people with non-muscle invasive bladder cancer, scientists from The University of Texas M. D. Anderson Cancer Center reported today at the American Association for Cancer Research Frontiers in Cancer Prevention Research Conference.

Released: 7-Dec-2009 3:00 PM EST
Drug Shows Positive Responses, Low Side-Effects in Multiple Myeloma
University of Texas MD Anderson Cancer Center

The second-generation proteasome inhibitor carfilzomib is showing noteworthy response rates and low levels of adverse side effects among multiple myeloma patients in a phase II clinical trial, researchers reported today at the 51st Annual Meeting of the American Society of Hematology.

Released: 7-Dec-2009 3:00 PM EST
Second-line CML Drugs Evoke Faster Response than Front-line Therapy
University of Texas MD Anderson Cancer Center

Two medications approved as treatment for drug-resistant chronic myeloid leukemia continue to provide patients with quicker, better responses as a first treatment than the existing front-line drug, researchers at The University of Texas M. D. Anderson Cancer Center reported at the 51st Annual Meeting of the American Society of Hematology.

Released: 7-Dec-2009 2:45 PM EST
JAK2 Inhibitor Demonstrates Effective, Durable Control of Myelofibrosis
University of Texas MD Anderson Cancer Center

A first-in-its class oral medication provides significant and durable relief for patients with a rare, debilitating and lethal bone marrow disorder called myelofibrosis, researchers at The University of Texas M. D. Anderson Cancer Center reported today at the 51st Annual Meeting of the American Society of Hematology.

Released: 7-Dec-2009 2:45 PM EST
Drug Shows Promise for T315I-Mutated Chronic Myeloid Leukemia
University of Texas MD Anderson Cancer Center

Results from a phase II clinical trial indicate a novel drug may provide a treatment option for chronic myeloid leukemia (CML) patients who do not respond to current therapies, researchers from The University of Texas M. D. Anderson Cancer Center report today at the 51st Annual Meeting of the American Society of Hematology.

7-Dec-2009 12:50 PM EST
Genetic Variations Indicate Risk of Recurrence, Secondary Cancer Among Head and Neck Cancer Patients
University of Texas MD Anderson Cancer Center

Eighteen single-point genetic variations indicate risk of recurrence for early-stage head and neck cancer patients and their likelihood of developing a second type of cancer, researchers at The University of Texas M. D. Anderson Cancer Center reported at the American Association for Cancer Research Frontiers in Cancer Prevention Research Conference.

Released: 3-Dec-2009 11:15 AM EST
Share the Health: M. D. Anderson's Holiday Gift Guide
University of Texas MD Anderson Cancer Center

This holiday season, experts at The University of Texas M. D. Anderson Cancer Center encourage shoppers to purchase gifts that offer health benefits for recipients. M. D. Anderson’s 2009 holiday gift guide has healthy options for everyone in the family.

1-Dec-2009 2:55 PM EST
Movies Promote Smoking Among Mexican-American Adolescents
University of Texas MD Anderson Cancer Center

The more movie scenes of smoking they watch, the more likely Mexican-American youths are to experiment with smoking, researchers at The University of Texas M. D. Anderson Cancer Center and Dartmouth College report in the December issue of Cancer Epidemiology, Biomarkers and Prevention. Article is available in Spanish.

1-Dec-2009 2:45 PM EST
Acculturation Influences Smoking Cessation by Latino Men
University of Texas MD Anderson Cancer Center

Latino men who are more adapted to U.S. culture are more likely to quit smoking than their less-acculturated counterparts, according to research by scientists at The University of Texas M. D. Anderson Cancer Center published in the December issue of Cancer Epidemiology, Biomarkers and Prevention, which has a special emphasis on tobacco. Article is available in Spanish

Released: 2-Dec-2009 3:00 PM EST
Era of Hope Scholar Award Funds Unique Breast Cancer Research
University of Texas MD Anderson Cancer Center

A novel approach to detecting and targeting flaws in first line of defense against cancer has earned an Era of Hope Scholar Award from the U.S. Department of Defense for a scientist at The University of Texas M. D. Anderson Cancer Center.

1-Dec-2009 1:25 PM EST
Criteria Based on Standard CT Imaging Taken Post Avastin-Chemotherapy Regimen May Predict Overall Survival in Patients with Metastatic Colorectal Cancer
University of Texas MD Anderson Cancer Center

Using routine computed tomography (CT) imaging to analyze form and structural changes to colorectal liver metastasis after bevacizumab and chemotherapy may predict overall survival, according to research from The University of Texas M. D. Anderson Cancer Center.

1-Dec-2009 3:15 PM EST
Susceptibility Predicts Smoking Risk among Mexican-American Youth
University of Texas MD Anderson Cancer Center

Whether non-smoking Mexican-American adolescents go on to experiment with smoking depends largely on their initial attitude toward the habit, researchers at M. D. Anderson Cancer Center report in the December issue of Cancer Epidemiology, Biomarkers and Prevention, a journal of the American Association for Cancer Research. Spanish version of this article is available.

20-Nov-2009 4:55 PM EST
Crosstalk Between Critical Cell-Signaling Pathways Holds Clues To Tumor Invasion and Metastasis
University of Texas MD Anderson Cancer Center

Two signaling pathways essential to normal human development - the Wnt/Wingless (Wnt) and epidermal growth factor receptor (EGFR) pathways - interact in ways that can promote tumor cell invasion and metastasis, researchers from The University of Texas M. D. Anderson Cancer Center report in the Nov. 25 issue of Molecular Cell.

Released: 23-Nov-2009 2:00 PM EST
M. D. Anderson Brings Baseball Hall of Famer Hank Aaron to Houston for A Conversation With a Living Legend
University of Texas MD Anderson Cancer Center

Hall of Famer and all-time batting record holder Hank Aaron will share personal stories from his 23-year major league career during A Conversation With a Living Legend, an annual fundraising luncheon, Dec. 3 at the Hilton Americas Hotel in Houston. Funds will benefit cancer research and patient care programs at The University of Texas M. D. Anderson Cancer Center.

Released: 11-Nov-2009 4:15 PM EST
M. D. Anderson Offers Guidance on Choosing Tobacco Cessation Products
University of Texas MD Anderson Cancer Center

Whether you smoke three cigarettes or three packs of cigarettes a day, kicking the habit is difficult. Various nicotine replacement products are on the market to make quitting easier. But which product is right for you? Experts from The University of Texas M. D. Anderson Cancer Center are here to help.

Released: 10-Nov-2009 12:15 PM EST
Elizabeth Travis, Receives 2009 AAMC Women in Medicine Leadership Development Award
University of Texas MD Anderson Cancer Center

Elizabeth Travis, Ph.D., associate vice president for Women Faculty Programs and professor in the Departments of Experimental Radiation Oncology and Pulmonary Medicine at The University of Texas M. D. Anderson Cancer Center, has received the 2009 Association of American Medical Colleges (AAMC) Women in Medicine Leadership Development Award.

Released: 9-Nov-2009 2:25 PM EST
M. D. Anderson Chief Nursing Officer Named AAN Fellow
University of Texas MD Anderson Cancer Center

The University of Texas M. D. Anderson Cancer Center's top nursing executive has been recognized with nursing's highest honor.

4-Nov-2009 7:30 PM EST
Green Tea Shows Promise as Chemoprevention Agent for Oral Cancer
University of Texas MD Anderson Cancer Center

Green tea extract has shown promise as cancer prevention agent for oral cancer in patients with a pre-malignant condition known as oral leukoplakia, according to researchers at The University of Texas M. D. Anderson Cancer Center.

Released: 3-Nov-2009 2:30 PM EST
Study of Concurrent Radiotherapy, Chemotherapy Shows Promise in Small Cell Lung Cancer
University of Texas MD Anderson Cancer Center

Treating limited stage small cell lung cancer(LSCL) with a combination of accelerated high-dose radiotherapy and chemotherapy has shown encouraging results, opening the door to larger scale investigation, according to new research from The University of Texas M. D. Anderson Cancer Center.

2-Nov-2009 1:30 PM EST
Early Stage, HER2 Positive Breast Cancer Patients at Increased Risk of Recurrence
University of Texas MD Anderson Cancer Center

Early-stage breast cancer patients with HER2 positive tumors one centimeter or smaller are at significant risk of recurrence of their disease, compared to those with early-stage disease who do not express the aggressive protein, according to a study led by researchers at The University of Texas M. D. Anderson Cancer Center.

Released: 2-Nov-2009 9:00 AM EST
Academic Pressures and Stress Take Toll on Scientists, Clinicians
University of Texas MD Anderson Cancer Center

On average, research shows, the United States loses the equivalent of at least one entire medical school class each year to suicide1 - as many as 400 physicians. The book Faculty Health in Academic Medicine: Scientists, Physicians, and the Pressures of Success (Humana Press/Springer), by faculty at The University of Texas M. D. Anderson Cancer Center and other national medical experts, breaks new ground in a first-of-its-kind look at faculty health.

   
28-Oct-2009 3:35 PM EDT
Th17 Cells Summon an Immune System Strike Against Cancer
University of Texas MD Anderson Cancer Center

A specific type of T helper cell awakens the immune system to the stealthy threat of cancer and triggers an attack of killer T cells custom-made to destroy the tumors, scientists from The University of Texas M. D. Anderson Cancer Center report in the early online edition of the journal Immunity.

Released: 26-Oct-2009 3:45 PM EDT
M. D. Anderson Redefines Screening Guidelines for Breast, Cervical and Colorectal Cancers
University of Texas MD Anderson Cancer Center

Drawing on years of experience in cancer research and patient care, The University of Texas M. D. Anderson Cancer Center released today the most comprehensive, risk-based screening guidelines publicly available to date for breast, cervical and colorectal cancers.

Released: 20-Oct-2009 4:10 PM EDT
Cosmetic Breast Implants Do Not Interfere With Detecting Breast Cancer
University of Texas MD Anderson Cancer Center

October is Breast Cancer Awareness Month, and breast experts from The University of Texas M. D. Anderson Cancer Center agree that getting breast implants does not increase a woman’s breast cancer risks or prevent her from getting accurate mammogram test results.

Released: 9-Oct-2009 3:30 PM EDT
Breast Cancer Patients With High Risk Gene Diagnosed Six Years Earlier Than Generation Before
University of Texas MD Anderson Cancer Center

Women with a deleterious gene mutation are diagnosed with breast cancer six years earlier than relatives of the previous generation who also had the disease and/or ovarian cancer, according to new research from The University of Texas M. D. Anderson Cancer Center.

Released: 9-Oct-2009 3:00 PM EDT
Study Finds No Relationship Between PCR Rate and Race in Women with Breast Cancer
University of Texas MD Anderson Cancer Center

Locally advanced breast cancer patients who received the same class of neoadjuvant chemotherapy were found to have no evidence of disease at the time of their surgery, or achieved pathological complete response, at the same rate regardless of race, according to researchers at The University of Texas M. D. Anderson Cancer Center.

Released: 9-Oct-2009 1:30 PM EDT
KEAP1 Keeps Major Cancer-Promoting Protein at Bay
University of Texas MD Anderson Cancer Center

A tumor-suppressing protein snatches up an important cancer-promoting enzyme and tags it with molecules that condemn it to destruction, a research team led by scientists at The University of Texas M. D. Anderson Cancer Center reports this week in the journal Molecular Cell.

Released: 9-Oct-2009 10:00 AM EDT
Researchers Report Benefits of New Standard Treatment Study for Rare Pediatric Brain Cancer
University of Texas MD Anderson Cancer Center

A team of researchers led by The University of Texas M. D. Anderson Cancer Center unveiled results today from the largest-ever collaborative study addressing the treatment of a rare pediatric brain tumor. The findings suggest a new standard protocol could improve survival nearly two-fold for pediatric patients with choroid plexus tumors, as reported at the 41st Annual Meeting of the International Society of Pediatric Oncology (SIOP).

Released: 7-Oct-2009 10:10 AM EDT
M. D. Anderson Team Chosen to Help Navigate Cancer Genome Atlas
University of Texas MD Anderson Cancer Center

The Cancer Genome Atlas (TCGA) will fund an effort by scientists at The University of Texas M. D. Anderson Cancer Center to siphon buckets of meaningful information from an ocean of data about the aberrant genetics that drive human cancers.

Released: 5-Oct-2009 9:00 PM EDT
Stereotactic Radiosurgery Preferred Method of Treating Cancer Patients with Brain Metastases
University of Texas MD Anderson Cancer Center

Cancer patients who receive stereotactic radiosurgery (SRS) and whole brain radiation therapy (WBRT) for the treatment of metastatic brain tumors have more than twice the risk of developing learning and memory problems than those treated with SRS alone, according to researchers at The University of Texas M. D. Anderson Cancer Center.



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