In a study publishing December 20 in Nature Cancer, UCSF researchers found that phenotype switching, as opposed to genetic evolution, may be the escape mechanism that explains the failure of precision therapies to date. They found that some cells shift to a mesenchymal, radiation-resistant phenotype (state) as a stress response following standard therapy.
UC San Francisco surgeons have performed the health system’s 20,000th solid organ transplant, making it just the third in the nation to reach that milestone. The surgery also marked UCSF Health’s first donation after circulatory death (DCD) heart transplant, a procedure performed by only about twenty health systems in the U.S.
Alan P. Venook, MD, a renowned expert in colorectal and liver cancers, has been announced as one of the winners of the 2022 Luminary Awards in Gastrointestinal (GI) Cancers. Venook is being recognized for his achievements in the clinical practice and research of gastrointestinal cancers.
In the past several years, myocarditis has been of public interest because of cases associated with vaccines for SARS-CoV2 or related conditions. Another form of myocarditis has been linked to immune checkpoint inhibitors (ICIs) used in cancer care. ICI-induced myocarditis is a potentially fatal side effect of ICI usage, and it appears that the adverse cardiac effects may disproportionally impact female patients. This finding is in contrast to other forms of myocarditis, with more cases reported in male patients.
The UCSF Hypoxia Laboratory and UCSF Center for Health Equity in Surgery and Anesthesia (CHESA) are formally launching the Open Oximetry Project, a multi-year initiative to improve access to safe pulse oximeters worldwide, by sharing data and creating new standards and technologies for oximeter validation that better account for skin color.
Gastrointestinal surgeons at UC San Francisco have performed the first pure robotically assisted Whipple surgery in San Francisco. The surgery was recently performed on a 77-year-old pancreatic cancer patient by surgeons Mohamed Adam, MD, and Adnan Alseidi, MD, MEd, FACS.
Ophthalmologists may be able to safely cut back on having anesthesiologists or nurse anesthetists routinely at bedside during cataract surgery, which accounts for more than two million surgeries per year in the U.S., according to a study publishing Oct. 3 in JAMA Internal Medicine.
UCSF Health’s Heart and Vascular Center is welcoming Sammy Elmariah, MD, MPH, FACC, FAHA, FSCAI, as chief of its division of Interventional Cardiology and medical director of the division’s cardiac catheterization lab. Elmariah is a recognized expert in structural heart disease interventions and catheter-based valve therapies.
In a study publishing in Nature Medicine on September 22, 2022, University of California San Francisco researchers Adam Staffaroni, PhD, and Adam Boxer, MD, PhD, combined and harmonized clinical, neuroimaging, and fluid biomarkers from nearly all familial FTD clinical research participants across North America and Europe. With that data, they developed models of clinical and biomarker dynamics to determine the temporal sequence of biomarker and clinical changes in f-FTD before disease progression begins.
UCSF Health is recruiting patients for the only FDA-approved study of the use of single port robotic technology for colorectal surgery in the United States. UC San Francisco clinical investigators Ankit Sarin, MD, FACS, and Hueylan Chern, MD, initiated the study which will evaluate whether single port robot technology is more advantageous than the current multi-port technology used in colorectal surgery.
Step counts—a measure of physical activity—were markedly lower early in the COVID-19 pandemic than pre-pandemic and remained lower, on average, in the two years following the onset of the global pandemic.
A UC San Francisco-led team of international researchers has outlined the comprehensive immune landscape and microbiome of pancreatic cysts as they progress from benign cysts to pancreatic cancer. Their findings, publishing August 31 in Lancet Gastroenterology and Hepatology, could reveal the mechanism of neoplastic progression and provide targets for immunotherapy to inhibit progression or treat invasive disease.
When our eyes move during REM sleep, we’re gazing at things in the dream world our brains have created, according to a new study by researchers at UC San Francisco. The findings shed light not only into how we dream, but also into how our imaginations work.
UCSF Medical Center has been ranked among the country’s finest hospitals in adult care by U.S. News & World Report’s prestigious Best Hospitals survey. It was named to the Best Hospitals Honor Roll for 2022-23, a distinction earned by 20 medical centers nationwide that deliver the highest quality care in numerous specialties, procedures and conditions
Cardiothoracic surgeons at UC San Francisco have performed the first robotically assisted mitral value surgery in San Francisco. The surgery was recently performed on a 63-year-old patient who had mitral valve prolapse.
UCSF is welcoming its first patients to the Nancy Friend Pritzker Psychiatry Building, a one-of-a-kind treatment center that aims to redefine mental health services and make a bold statement against stigma.
Prescott Woodruff, MD, MPH, a renowned leader in the pathogenesis and treatment of airway disease, has been appointed chief of UC San Francisco’s Division of Pulmonary, Critical Care, Allergy and Sleep Medicine. Prescott will assume the role of chief on July 1.
Jack S. Resneck Jr., MD, was inaugurated today as the 177th president of the American Medical Association (AMA). Resneck is a dermatologist, professor and vice-chair of the Department of Dermatology at UC San Francisco. Following a year-long term as president-elect of the nation’s premier physician organization, Resneck today assumed the office of AMA president.
As a worldwide shortage of contrast dye for medical imaging continues, a new UC San Francisco research letter in JAMA quantified strategies medical facilities can employ to safely reduce dye use in computed tomography (CT) by up to 83%. CT is the most common use for the dye.
UC San Francisco’s Cardiovascular team is welcoming two highly regarded cardiac surgeons to its renowned program. The specialists will join the newly formed Advanced Heart Failure Comprehensive Care Center (AHF CCC).
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