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A UCLA-led has study found that after leaving the hospital, nearly two-thirds of Medicare beneficiaries hospitalized for acute ischemic stroke either died or were rehospitalized within a year. The findings point to an opportunity for more quality-of-care initiatives to improve stroke care, especially in transitioning to home, stroke rehabilitation and outpatient care.

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A new survey by an agency of the U.S. Department of Health and Human Resources has recognized the heart transplant program at Ronald Reagan UCLA Medical Center as the nation's best.

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By 2013, four million more kids are expected to come into the healthcare system, paid for by Medicaid. One huge managed-care Medicaid system—Los Angeles County—is not dealing effectively now one of its more vulnerable populations—children with ADHD. This paper details why this is so, and it raises a question--how will it cope with four million more children, and is it representative of other managed care systems nationally?

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A protein that is crucial for regulating the self-renewal of normal prostate stem cells, needed to repair injured cells or restore normal cells killed by hormone withdrawal therapy for cancer, also aids the transformation of healthy cells into prostate cancer cells, researchers at UCLA have found.

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Researchers with UCLA’s Jonsson Comprehensive Cancer Center have found that melanoma patients whose cancers are caused by mutation of the BRAF gene become resistant to a promising targeted treatment through another genetic mutation or the overexpression of a cell surface protein, both driving survival of the cancer and accounting for relapse.

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UCLA researchers have pinpointed the culprit behind chronic rejection of heart, lung and kidney transplants. Published in the Nov. 23 edition of Science Signaling, their findings suggest new therapeutic approaches for preventing transplant rejection and sabotaging cancer growth.

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UCLA researchers have identified in the mouse the molecular cascade that drives the process of reconnection or sprouting in the adult brain after stroke.

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New techniques now being used at UCLA allow doctors to more precisely target certain areas of the heart to stop ventricular arrhythmias — serious abnormal rhythms in the heart's lower chambers — in high-risk patients.

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A monoclonal antibody targeting a well known cell surface protein inhibited prostate cancer growth and metastasis in an aggressive form of the disease that did not respond to hormone therapy, according to a study by researchers with the UCLA Department of Urology and UCLA’s Jonsson Comprehensive Cancer Center.

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Research on hyperemesis gravidarum—an extreme form of pregnancy-related morning sickness—suggests not only that the condition could be genetic but that women with sisters who had HG could have a more than 17-fold risk of experiencing the debilitating condition too.

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Humans can actually regulate the activity of specific neurons in the brain, increasing the firing rate of some while decreasing the rate of others. And study subjects proved this by manipulating an image on a computer screen using only their thoughts.

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A new UCLA study published in the Nov. 11 issue of the journal Nature offers insights into a major limitation in the brain's ability to recover function after a stroke and identifies a promising medical therapy to help overcome this limitation.

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Using a blend of brain imaging and genetic detective work, scientists at UCLA’s David Geffen School of Medicine and Semel Institute for Neuroscience and Human Behavior are the first to illustrate how genetic variants rewire the brain. Published in the Nov. 3 online edition of Science Translational Medicine, their discovery offers the crucial missing physical evidence that links altered genes to modified brain function and learning.

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A drug in testing to treat atherosclerosis significantly inhibited growth of ovarian cancer in both human cell lines and mouse models, the first such report of a peptide being used to fight malignancies, according to a study by researchers at UCLA’s Jonsson Comprehensive Cancer Center.

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Medical schools and clinics could boost the number of primary care physicians in medically underserved areas by selecting and encouraging students from these communities, who often exhibit a strong sense of responsibility for and identification with the people there.

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A new study found that racial and ethnic disparities among children with frequent ear infections can significantly influence access to health care resources.

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Researchers in the Radiation Oncology Department at UCLA’s Jonsson Comprehensive Cancer Center have received a $14 million grant to develop countermeasures that will help treat damage caused by radiological or nuclear threats such as a dirty bomb attack.

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The state stem cell agency today awarded grants totaling $10.4 million to three researchers with the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA to translate basic science into new and more effective therapies to regenerate bone and treat deadly brain cancers and corneal disorders that result in blindness.

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UCLA has received a $4.6 million grant from the National Institutes of Health to study ways to get HIV-positive men who have been released from Los Angeles County jails into medical care and on sustained treatment. The study — one of 12 taking place across the nation — could have a long-term impact on the HIV epidemic in Los Angeles.

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Curcumin, the major component in the spice turmeric, when combined with the drug Cisplatin enhances the chemotherapy’s suppression of head and neck cancer cell growth, researchers with UCLA’s Jonsson Cancer Center have found.

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UCLA scientists have discovered that exposing fetal neurons to higher than normal levels of a common immune protein leads to abnormal brain development in mice. The finding may provide new insights into factors contributing to human neurological disorders like schizophrenia and autism.

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More than 50 deep brain stimulation experts came together to pool their experience to better inform Parkinson's patients and their families about the potential of this treatment to help relieve symptoms.

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More than half of men dying of prostate cancer use hospice care – a significant increase over the last two decades – but most wait too long to enroll so they can’t take full advantage of the palliative care that could make their deaths easier, a study by researchers at UCLA’s Jonsson Comprehensive Cancer Center found.

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A consortium of five University of California medical schools, plus Cedars–Sinai Medical Center in Los Angeles, has received $9.9 million from the U.S. Department of Health and Human Services' Agency for Healthcare Research and Quality to research the use of wireless and telephone care management to reduce hospital readmissions for heart failure patients.

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UCLA has received a five-year, $12.5 million contract award from the National Heart, Lung and Blood Institute to spearhead an international consortium of medical experts that will study proteins that may be involved in the development of cardiovascular disease.

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Researchers at UCLA’s Jonsson Comprehensive Cancer Center have discovered a new cell signaling pathway that controls cell growth and development, a pathway that, when defective, helps promote the formation of several major forms of human cancer, including lymphoma and leukemia.

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Study finds no significant gender-based differences in response to two anti-HIV drugs and demonstrates it is possible to recruit large numbers of women into clinical trials. But women dropped out of trial at higher rates than men.

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A “test and treat” strategy, the leading proposal by the World Health Organization to combat HIV/AIDS in South Africa, is seriously flawed, say UCLA researchers.

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The UCLA Center on Aging's third annual "UCLA Technology and Aging Conference: Science Changing Lives," will feature national academic and industry leaders who will explore cutting-edge innovations affecting every aspect of life, from video games for seniors and remote health monitoring to medical robotics and the latest imaging tools for diagnosis and disease management.

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Chronic stress acts as a sort of fertilizer that feeds breast cancer progression, significantly accelerating the spread of disease in animal models, researchers at UCLA’s Jonsson Comprehensive Cancer Center have found.

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UCLA has been selected by the U.S. Department of Homeland Security's Science and Technology Directorate to help establish guidelines for the health and safety of firefighters in the field.

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UCLA researchers found that adolescents from Latin American and Asian backgrounds experienced more discrimination than their peers from European backgrounds and that the discrimination came not only from other adolescents but from adults as well. Discrimination impacted their grade-point averages and their health, and was associated with depression, distress and lower levels of self-esteem.

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Female induced pluripotent stem (iPS) cells, reprogrammed from human skin cells into cells that have the embryonic-like potential to become any cell in the body, retain an inactive X chromosome, stem cell researchers at UCLA have found.

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The end of smallpox in 1979 has led to a sharp rise in monkeypox, a related but less lethal viral infection. The disease is spreading in Africa, with sporadic outbreaks elsewhere, including the U.S.

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UCLA researchers have found that a variation in a gene on the sex chromosome X may enhance an immune response that leads to lupus in men.

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Adult stem cells that are vital for airway repair in the lung but that persist in areas where pre-cancerous lesions are found are associated with a poor prognosis in patients who develop cancer, even those with early stage disease, researchers at UCLA’s Jonsson Comprehensive Cancer Center have found.

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UCLA researchers have discovered that how you respond to social stress may negatively affect health

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In one of the first efforts of its kind, UCLA researchers have taken mammalian genome maps, including human maps, one step further by showing not just the order in which genes fall in the genome but which genes actually interact. The findings will help researchers better understand which genes work together and shed light on how they collaborate to help cells thrive or die.

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A new study by researchers from UCLA and Harvard University has found disparities among children suffering from repeated ear infections.

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Researchers at UCLA’s Jonsson Comprehensive Cancer Center and the departments of Chemistry and Biochemistry and Pathology and Laboratory Medicine have uncovered a role for an essential cell protein in shuttling RNA into the mitochondria, the energy-producing “power plant” of the cell.

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Pancreatic cancers use the sugar fructose, very common in the Western diet, to activate a key cellular pathway that drives cell division, helping the cancer to grow more quickly, a study by researchers at UCLA’s Jonsson Comprehensive Cancer Center has found.

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New study suggests that disparities in cardiovascular disease risk in the United States are due less to race or ethnicity than to socioeconomic status.

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UCLA scientists have identified for the first time a cell-of-origin for human prostate cancer, a discovery that could result in better predictive and diagnostics tools and the development of new and more effective targeted treatments for the disease.

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A new UCLA study shows that female medical students volunteer for leadership roles in the classroom far less than their male peers. Subtle encouragement from teachers, however, can even out the playing field.

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A study led by UCLA tested a new performance intervention to help improve adherence to national guideline-recommended therapies for heart failure patients in an outpatient setting.

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The UCLA Health System has launched the new UCLA Hand Transplantation Program, the first of its kind on the West Coast and only the fourth such center in the United States.

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Patients with deadly glioblastomas who received high doses of radiation that hit a portion of the brain that harbors neural stem cells had double the progression-free survival time as patients who had lower doses or no radiation targeting the area, a study from the Radiation Oncology Department at UCLA’s Jonsson Comprehensive Cancer Center has found.

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A large academic study has demonstrated structural changes in specific brain regions in female patients with irritable bowel syndrome (IBS), a condition that causes pain and discomfort in the abdomen, along with diarrhea, constipation or both. According to researchers, the finding removes the idea once and for all that IBS symptoms are not real and are 'only psychological.'

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Scientists at the UCLA Broad Stem Cell Research Center have described a population of cells that mark the very first stage of differentiation of human embryonic stem cells as they enter a developmental pathway that leads to production of blood, heart muscle, blood vessels and bone.

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A UCLA research team has uncovered new genetic clues about how neurofibromatosis type 1 (NF1) disrupts working memory. The findings suggest a potential drug target for correcting NF1-related learning disabilities.