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Released: 13-Mar-2007 12:00 AM EDT
Infection Detectives Use Disease ‘Fingerprints’ to Track Common Infections in Children
UT Southwestern Medical Center

Infectious disease specialists at UT Southwestern Medical Center have found a new method for identifying suspect viruses and bacteria that cause some of the most common acute infections in children.

5-Mar-2007 4:15 PM EST
Cannibalistic Signals Help Mammalian Embryos Develop Normally
UT Southwestern Medical Center

A cannibalistic process called autophagy spurs dying embryonic stem cells to send "eat me" and "come get me" signals to have their corpses purged, a last gasp that paves the way for normal mammalian development, UT Southwestern Medical Center researchers have found.

Released: 27-Feb-2007 12:00 AM EST
Innovative Treatment for Migraines Combines Botox and Surgery
UT Southwestern Medical Center

Five years ago, Sharon Schafer Bennett suffered from migraines so severe that the headaches disrupted her life, kept her from seeking a job and interfered with participation in her children's daily activities.

Released: 19-Feb-2007 9:00 AM EST
CRP Liver Protein Induces Hypertension, Researchers Have Found
UT Southwestern Medical Center

C-Reactive Protein, widely regarded as a key player in risk factor for hypertension and other forms of cardiovascular disease, may also plays a direct role in the onset of hypertension, researchers at UT Southwestern Medical Center have found.

13-Feb-2007 3:10 PM EST
Studies of Population Genetics, Evolution Are an Exercise in Bad Taste
UT Southwestern Medical Center

Scientific studies of why foods such as Brussels sprouts and stout beer are horribly bitter-tasting to some people but palatable to others are shedding light on a number of questions, from the mechanisms of natural selection to understanding how our genes affect our dietary habits.

2-Feb-2007 8:00 PM EST
Sea Creature's Toxin Could Lead to Promising Cancer Treatment
UT Southwestern Medical Center

A toxin derived from a reclusive sea creature resembling a translucent doughnut has inspired UT Southwestern Medical Center researchers to develop a related compound that shows promise as a cancer treatment.

1-Feb-2007 3:20 PM EST
Supplemental Therapy Can Ease Pain for People Suffering from Common Jaw Disorder
UT Southwestern Medical Center

A new supplemental therapy that teaches pain coping and biofeedback skills can reduce pain, the potential for chronic pain and health-care costs for millions of Americans suffering from a common jaw disorder, UT Southwestern Medical Center researchers have found.

Released: 1-Feb-2007 2:40 PM EST
New Biomarker Test Could Predict Outcome for Bladder Cancer Patients
UT Southwestern Medical Center

A set of molecular biomarkers might better predict the recurrence of bladder cancer than conventional prognostic features such as the stage or grade of the malignancy at the time it is discovered, UT Southwestern Medical Center researchers have found.

Released: 31-Jan-2007 12:00 AM EST
Different Treatment May be Needed for Infection-Related Breathing Problems
UT Southwestern Medical Center

New research suggests that different treatments may be needed for chronic asthma, depending on whether it results from allergies or lung infections.

Released: 29-Jan-2007 3:45 PM EST
Risk for Stroke, Death Not Higher for Sickle Cell Children with Early Complications
UT Southwestern Medical Center

Children with sickle cell disease who experienced major complications such as pain and lung disease early in life are at no greater risk for stroke or death during later childhood, new research from UT Southwestern Medical Center shows.

24-Jan-2007 3:10 PM EST
Novel Laboratory Technique Nudges Genes Into Activity
UT Southwestern Medical Center

A new technique that employs RNA, a tiny chemical cousin of DNA, to turn on genes could lead to therapeutics for conditions in which nudging a gene awake would help alleviate disease, researchers at UT Southwestern Medical Center say.

Released: 16-Jan-2007 12:00 AM EST
Napoleon’s Mysterious Death Unmasked
UT Southwestern Medical Center

A new investigation into Napoleon Bonaparte's cause of death might finally put to rest nearly 200 years of lingering mysteries about the illness that killed the French emperor during his island exile, a UT Southwestern Medical Center scientist reports.

Released: 8-Jan-2007 11:15 AM EST
Tracing Agent, Microbubbles, Ultrasound Combo Helps Test Cancer Therapy’s Effectiveness
UT Southwestern Medical Center

An inexpensive tracing agent used in combination with ultrasound can pinpoint how effectively drugs targeting pancreatic cancer work, researchers at UT Southwestern Medical Center have demonstrated for the first time.

20-Dec-2006 6:10 PM EST
Molecular ‘On/Off Switch’ Controls Immune Defenses Against Viruses
UT Southwestern Medical Center

Much like flipping a light switch, the hepatitis C virus turns on human immune defenses upon entering the body but also turns off those defenses by manipulating interaction of key cellular proteins, UT Southwestern Medical Center researchers have found.

22-Dec-2006 11:00 AM EST
Profiling of Cancer Genes May Lead to Better and Earlier Detection of Solid Human Cancers
UT Southwestern Medical Center

A research team at UT Southwestern Medical Center has for the first time identified several genes whose expression is lost in four of the most common solid human cancers "“ lung, breast, prostate and colon cancer.

13-Dec-2006 3:25 PM EST
Drug That Chokes Off Tumor Blood Vessels Offers New Hope to Lung Cancer Patients
UT Southwestern Medical Center

Patients suffering from the most common type of lung cancer experienced a 20-percent improvement in overall survival in a national clinical trial of a drug that chokes off the blood vessels nourishing tumors, a multicenter study has found.

Released: 13-Dec-2006 12:00 AM EST
Antibiotic Ear Drops Favored Over Popular Oral Antibiotics for Ear Infections
UT Southwestern Medical Center

A multicenter study on treating common ear infections in children with ear tubes adds to a growing body of evidence that favors antibiotic ear drops over antibiotics swallowed in pill or liquid form in such cases, a UT Southwestern Medical Center researcher reports.

Released: 12-Dec-2006 12:00 AM EST
Even Slight Holiday Weight Gain Can Set Stage for Obesity, Health Risks
UT Southwestern Medical Center

Although some Americans gain five to seven pounds with a diet of big meals and sweets between Thanksgiving and New Year's Day, most people only gain a pound or two during the holidays, according to a UT Southwestern Medical Center registered dietitian.

Released: 11-Dec-2006 3:40 PM EST
UT Southwestern Ranked Among America’s Top Biomedical Research Universities
UT Southwestern Medical Center

UT Southwestern Medical Center ranked among the top 10 American institutions in three of the six biomedical fields assessed in an independent analysis of scientific research impact.

Released: 5-Dec-2006 4:30 PM EST
Molecular 'Marker' on Stem Cells Aids Research, Perhaps Therapies
UT Southwestern Medical Center

A sugar molecule present on embryonic stem cells also has been found on the surface of a type of adult stem cell, a discovery that may help researchers isolate and purify adult stem cells for use in therapies aimed at bone healing, tendon repair and cartilage regeneration, researchers at UT Southwestern Medical Center report.

Released: 4-Dec-2006 6:30 PM EST
Hair-Growth Drug Artificially Lowers Psa Levels in Prostate Cancer Screening
UT Southwestern Medical Center

The popular hair-growth drug finasteride, taken by millions of balding men, artificially lowers the results of the prostate-specific antigen (PSA) test, the standard screening test for prostate cancer, a multicenter study has found.

1-Dec-2006 4:40 PM EST
Molecular ‘Marker’ on Stem Cells Aids Research, Perhaps Therapies
UT Southwestern Medical Center

A sugar molecule present on embryonic stem cells also has been found on the surface of a type of adult stem cell, a discovery that may help researchers isolate and purify adult stem cells for use in therapies aimed at bone healing, tendon repair and cartilage regeneration, researchers at UT Southwestern Medical Center report.

28-Nov-2006 3:30 PM EST
Pregnant Women with Placental Infection Have Doubled Risk of Recurrence
UT Southwestern Medical Center

Pregnant women who develop an infection of the placenta or nearby membranes in their first pregnancy have twice the risk of getting it in their second pregnancy, researchers at UT Southwestern Medical Center have found.

Released: 28-Nov-2006 12:00 AM EST
Seniors More at Risk for Complications, Death from Large Scale Weight-Loss Surgery
UT Southwestern Medical Center

The first large-scale review of weight-loss surgeries performed on older adults suggests bariatric procedures should generally be limited to people younger than age 65, researchers at UT Southwestern Medical Center have found.

Released: 28-Nov-2006 12:00 AM EST
Surgeons Perform First Robot-Assisted Procedures in Weight Loss, Colon and Gastric Fields
UT Southwestern Medical Center

UT Southwestern Medical Center surgeons are the first in North Texas to perform robotically assisted laparoscopic gastric-bypass and colon-resections surgeries.

17-Nov-2006 11:55 AM EST
Measuring Fetal Oxygen Does Not Reduce Caesarean Rate
UT Southwestern Medical Center

Measuring the amount of oxygen in the blood of a fetus during labor has no bearing on whether a Caesarean section is performed and does not affect the health of the newborn baby, researchers at UT Southwestern Medical Center have found in a multicenter study.

Released: 20-Nov-2006 12:00 AM EST
Survivors of Childhood Leukemia, Brain Tumors More at Risk for Strokes Later in Life
UT Southwestern Medical Center

Children who are successfully treated for brain tumors or leukemia are more likely to have strokes later in life, according to new research from UT Southwestern Medical Center.

Released: 20-Nov-2006 12:00 AM EST
Holiday Gluttony Can Spell Disaster for Undiagnosed Diabetics
UT Southwestern Medical Center

Hearty feasts and couch-potato marathons are holiday traditions, but UT Southwestern Medical Center experts warn that packing on pounds and not exercising could be deadly for the 6 million Americans who have diabetes and don't even know it.

Released: 16-Nov-2006 12:00 AM EST
Exposure to Dioxins Influences Male Reproductive System
UT Southwestern Medical Center

A dioxin toxin contained in the herbicide Agent Orange affects male reproductive health by limiting the growth of the prostate gland and lowering testosterone levels, researchers at UT Southwestern Medical Center have found in a cohort study of more than 2,000 Air Force veterans who served during the Vietnam War.

Released: 15-Nov-2006 12:00 AM EST
Holiday Season Could Ring in “Heartburn Season”
UT Southwestern Medical Center

Making merry is often synonymous with overindulging "“ whether from holiday feasts or rich desserts or alcoholic beverages "“ ringing in the holiday season as "heartburn season"

9-Nov-2006 3:10 PM EST
Micro Molecules Contribute Mightily to Heart Problem
UT Southwestern Medical Center

Tiny bits of RNA "“ a chemical cousin of DNA "“ play a large role in causing enlargement of the heart, which is a major risk factor for heart failure and sudden death, researchers at UT Southwestern Medical Center have discovered.

Released: 7-Nov-2006 4:30 PM EST
Gene Linked with Mental Illness Shapes Brain Region
UT Southwestern Medical Center

A gene variant associated with mental illness goes hand-in-hand with enlargement of a brain region that handles negative emotions, researchers at UT Southwestern Medical Center and the Central Texas Veterans Health Care System have found.

27-Oct-2006 7:00 PM EDT
Carefully Monitored Treatment Can Help Two-thirds of Those Who Suffer from Depression
UT Southwestern Medical Center

More than two-thirds of people who suffer from major depression can become symptom-free if they are willing to work with their doctors and try various treatments to determine which work best for them, which may involve taking different antidepressants or adding cognitive therapy to the mix.

Released: 31-Oct-2006 12:00 AM EST
Drug Prescribed for Migraines and Seizures Increases Risk of Kidney Stones
UT Southwestern Medical Center

Topiramate (Topamax), a drug commonly prescribed to treat seizures and migraine headaches, can increase the propensity of calcium phosphate kidney stones, researchers at UT Southwestern Medical Center have found.

30-Oct-2006 1:30 PM EST
Analysis of Breast-Cancer Gene Role Offers Promising Target for Drugs to Stop Or Slow Progression
UT Southwestern Medical Center

Researchers at UT Southwestern Medical Center have for the first time described how multiple copies of a gene are responsible for metastases in early-stage breast cancer and poor prognosis for patients.

Released: 26-Oct-2006 4:35 PM EDT
Test Reveals Effectiveness of Potential Huntington’s Disease Drugs
UT Southwestern Medical Center

A test using cultured cells provides an effective way to screen drugs against Huntington's disease and shows that two compounds "“ memantine and riluzole "“ are most effective at keeping cells alive under conditions that mimic the disorder, UT Southwestern Medical Center researchers report.

Released: 24-Oct-2006 3:30 PM EDT
New Nationwide Study on Leading Cause of Vision Loss for Seniors
UT Southwestern Medical Center

UT Southwestern Medical Center is participating in a nationwide study investigating whether modified combinations of vitamins, minerals and fish oil products can slow the progression of vision loss from age-related macular degeneration.

Released: 22-Oct-2006 1:40 PM EDT
New Lab Mice Pave Way for Novel Studies of Human Infections
UT Southwestern Medical Center

A new type of laboratory mouse developed at UT Southwestern Medical Center can fight certain infections the same way humans do, making the rodents very useful for novel studies of human-pathogen interaction and developing disease therapies.

Released: 19-Oct-2006 8:50 AM EDT
New Asthma Medicine Targeting Vulnerable Inner-City Children Tested
UT Southwestern Medical Center

UT Southwestern Medical Center is one of a handful of top research institutions evaluating a promising new medication researchers hope can reduce the severity and frequency of asthma attacks in inner-city children, a population known to have a high prevalence of severe asthma.

Released: 17-Oct-2006 12:05 AM EDT
Medical Center Recruiting Patients for Heart-Failure Device Study
UT Southwestern Medical Center

Physicians at UT Southwestern Medical Center are part of a multinational clinical trial evaluating a unique implantable device designed to treat a larger number of patients with heart failure.

Released: 12-Oct-2006 12:05 AM EDT
Researchers Refocus Studies on Patients with HIV, Hepatitis
UT Southwestern Medical Center

As HIV patients live longer thanks to advanced therapies, researchers are looking for better ways to treat accompanying maladies such as hepatitis that traditionally were not emphasized.

Released: 9-Oct-2006 6:15 PM EDT
Study Reveals Mechanism for Cancer-Drug Resistance
UT Southwestern Medical Center

Using the worm Caenorhabditis elegans, researchers at UT Southwestern Medical Center have discovered a mechanism by which cancer cells become resistant to a specific class of drugs.

Released: 7-Oct-2006 3:00 PM EDT
UT Regents, UT Southwestern Dedicate Advanced Medical Imaging Building
UT Southwestern Medical Center

UT Southwestern Medical Center dedicated the Bill and Rita Clements Advanced Medical Imaging Building "“ a state-of-the-art facility equipped with cutting-edge scientific tools that will enable researchers to peer deep inside the human body and learn more about the disease processes of diabetes, Alzheimer's, schizophrenia and many others.

3-Oct-2006 5:45 PM EDT
Natural Anti-Viral Enzyme Helps Keep Cancer Cells Alive
UT Southwestern Medical Center

A molecule that cells normally use to fight viruses is also involved in keeping cancer cells alive, researchers at UT Southwestern Medical Center have discovered.

Released: 3-Oct-2006 8:55 PM EDT
Study Unveils West Nile Virus Immune Evasion, Points to Vaccine Development
UT Southwestern Medical Center

West Nile virus evades the body's immune defenses by blocking immune signaling by a protein receptor, a finding that could pave the way for a vaccine to protect against North American strains of the virus, UT Southwestern Medical Center researchers report.

Released: 26-Sep-2006 12:00 AM EDT
UT Southwestern's Minimally Invasive Surgery Center One of Only Seven in North America
UT Southwestern Medical Center

UT Southwestern Medical Center's Southwestern Center for Minimally Invasive Surgery is one of seven facilities across the United States and Canada, and the only one in Texas, to garner first-time accreditation from the American College of Surgeons for its $2 million training lab.

Released: 20-Sep-2006 8:45 AM EDT
Different Techniques Can Help Ease Chronic Pain, Return Patients’ Smiles
UT Southwestern Medical Center

For National Pain Awareness Month, Dr. Leland Lou of UT Southwestern Medical Center is touting the various ways people with chronic pain "“ including more than 50 million Americans "“ can deal with chronic issues of head, back, cancer, arthritic and other types of pain, which can persist and cause physical debilitation and emotional stress.

Released: 14-Sep-2006 4:15 PM EDT
Scientist Receives NIH Director's Pioneer Award
UT Southwestern Medical Center

Dr. Thomas Kodadek, chief of the Division of Translational Research at UT Southwestern Medical Center, has won a National Institutes of Health Director's Pioneer Award, designed to support scientists of "exceptional creativity."

8-Sep-2006 8:50 AM EDT
Pre-Clinical Study Suggests How Steroid Can Reverse Post-Traumatic Stress
UT Southwestern Medical Center

Researchers at UT Southwestern Medical Center, working with mice, have shown how the body's own natural stress hormone can help lastingly decrease the fearful response associated with reliving a traumatic memory.

8-Sep-2006 8:55 AM EDT
Pre-Clinical Study Finds Parkinson’s Cell Death Blocked by Stopping Inflammatory Factor
UT Southwestern Medical Center

Blocking one of the body's natural inflammatory factors gives substantial protection against cell death in the brain associated with Parkinson's disease, researchers at UT Southwestern Medical Center have found in a study on rats.



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