Researchers from the UCLA AIDS Institute and colleagues have for the first time demonstrated that human blood stem cells can be engineered into cells that can target and kill HIV-infected cells — a process that potentially could be used against a range of chronic viral diseases.
Unlike the stereotype of runaway teens becoming long-term homeless, more than two-thirds of newly homeless youth resolve their family differences and go home. The key is family intervention.
A new study to determine whether the use of antithrombotic medications among stroke survivors increased over a seven-year period found that in each of the years, approximately 20 percent of survivors were not taking these medications — a figure that did not decrease during the time period. The study also found that individuals who were younger, female or Hispanic were less likely to be taking antithrombotic agents.
Hispanics in the U.S. with low levels of acculturation — meaning adaptation to American culture — had fewer HIV tests and no hepatitis C tests, were more likely to test positive for HIV, and had low levels of access to health care.
Scientists from the UCLA Department of Neurology have confirmed that blindness causes structural changes in the brain, indicating that the brain may reorganize itself functionally in order to adapt to a loss in sensory input.
Just as fly paper captures insects, an innovative new device with nano-sized features developed by researchers at UCLA is able to grab cancer cells in the blood that have broken off from a tumor. These cells, known as circulating tumor cells, or CTCs, can provide critical information for examining and diagnosing cancer metastasis, determining patient prognosis, and monitoring the effectiveness of therapies.
Titanium dioxide (TiO2) nanoparticles, found in everything from cosmetics to sunscreen to paint to vitamins, caused systemic genetic damage in mice, according to a comprehensive study conducted by researchers at UCLA’s Jonsson Comprehensive Cancer Center.
Baby Boomers may well be entering their 60s suffering far more disabilities than their counterparts did in previous generations, The findings, may be due in part to changing American demographics.
If humans are genetically related to chimps, why did our brains develop the innate ability for language and speech while theirs did not? Scientists suspect that part of the answer to the mystery lies in a gene called FOXP2. When mutated, FOXP2 can disrupt speech and language in humans. Now, a UCLA/Emory study reveals major differences between how the human and chimp versions of FOXP2 work, perhaps explaining why language is unique to humans.
The drug Sprycel, approved for use by the U.S. Food and Drug Administration in patients with chronic myeloid leukemia, significantly inhibited the growth and invasiveness of ovarian cancer cells and also promoted their death, a study by researchers with UCLA’s Jonsson Comprehensive Cancer Center found.
The effectiveness of a screening colonoscopy may depend on the time of day it is performed. According to a new UCLA study, early-morning colonoscopies yielded more polyps per patient than later screenings, and fewer polyps were found hour by hour as the day progressed. The findings point to the need for more research in this area to possibly improve outcomes for colonoscopy procedures.
New research suggests that a large number of HIV-positive individuals who reported feeling stigmatized also reported poor access to care or suboptimal adherence to antiretroviral therapy (ART).
UCLA scientists found that middle-aged and older adults with little Internet experience were able to trigger key centers in the brain that control decision-making and complex reasoning after just one week of surfing the Web. The findings suggest that Internet training can stimulate neural activation patterns and could potentially enhance brain function and cognition in older adults.
Researchers at UCLA’s Jonsson Comprehensive Cancer Center showed for the first time that the loss or decreased expression of the tumor suppressor gene PTEN plays a central role in the malignant transformation of benign nerve tumors called neurofibromas into a malignant and extremely deadly form of sarcoma.
Women who developed new-onset breast tenderness after starting estrogen plus progestin hormone replacement therapy were at significantly higher risk for developing breast cancer than women on the combination therapy who didn't experience such tenderness.
CNN talk show host Larry King and his wife, Shawn, will be honored at the 10th annual Mattel Party on the Pier, which benefits Mattel Children's Hospital UCLA.
While the human brain responds very differently to religious and nonreligious propositions, the process of believing or disbelieving a statement, whether religious or not, seems to be governed by the same areas in the brain.
UCLA's Dr. Pinchas Cohen has won a Transformative R01 (T-R01) award from the National Institutes of Health (NIH) to fund his innovative research on mitochondrial dysfunction.
UCLA scientists have identified two chemicals that convince cells to ignore premature signals to stop producing important proteins. The findings could lead to new medications for genetic diseases, such as cancer and muscular dystrophy, that are sparked by missing proteins.
Unfortunately, kids will probably be dismayed to learn that they will need an extra shot this year since recommendations call for children to receive both a seasonal flu vaccine and the H1N1 vaccine. Here are some tips to help kids survive the needle sticks.
Children in Southern California may soon be breathing a little easier, thanks to the UCLA Breathmobile, an asthma clinic on wheels that provides free diagnosis, treatment, medication and education at school sites for children with asthma.
Mattel Children’s Hospital UCLA announced the arrival of the 2009 holiday card collection created by pediatric patients.
Two researchers from UCLA’s Jonsson Comprehensive Cancer Center have won prestigious New Innovator Awards from the National Institutes of Health (NIH) to fund their leading-edge research.
For years, health conscious people have been taking antioxidants to reduce the levels of reactive oxygen in their blood and prevent the DNA damage done by free radicals, which are the result of oxidative stress. But could excessive use of antioxidants deplete our immune systems? Research at UCLA’s Jonsson Comprehensive Cancer Center has raised that question.
Billions of dollars are spent yearly targeting the toxic peptide amyloid beta to thwart Alzheimer’s— but what if this is the wrong target? A UCLA argues just that and says that a better working hypothesis is the "myelin model."
UCLA researchers found that drugs, electrical stimulation and regular exercise can enable paralyzed rats to walk and even run again. The finding may hold implications for human rehabilitation after spinal cord injuries.
Schools as well as the flu season have officially started, so this is a great time to follow some simple health tips that will help provide protection from not only H1N1 (swine flu), but seasonal influenza as well.
A nationwide study led by UCLA shows that clinicians may be able to accurately predict within a week whether a particular depression drug will be effective by using a non-invasive test that takes less than 15 minutes to administer.
The targeted therapy Avastin, alone and in combination with the chemotherapy drug CPT-11, significantly increased response rates, progression-free survival times and survival rates in patients with a deadly form of brain cancer that had recurred.
Mattel Children's Hospital UCLA has a new mobile tool to deliver music therapy and help pediatric patients cope with the fear, isolation and pain associated with being in the hospital.
Body mass index (BMI) readings may not be the best gauge of obesity in older adults. Instead, the ratio of waist size to hip size may be a better indicator when it comes to those over 70. Obesity is often associated with premature mortality.
UCLA and Pittsburgh researchers found that obese people had 8 percent less brain tissue than people with normal weight, while overweight people had 4 percent less tissue.
Got high cholesterol? You might want to consider a bone density test. A new UCLA study sheds light on the link between high cholesterol and osteoporosis and identifies a new way that the body’s immune cells play a role in bone loss.
A UCLA researcher concludes that sleep's primary function is to increase animals' efficiency and minimize their risk by regulating the duration and timing of their behavior.
A new study has found a striking correlation between teenage viewership and the frequency of alcohol advertising on cable television. The findings show that ads for beer, spirits and "alcopop" aired much more frequently when more teens were watching.
UCLA researchers have received 80 American Recovery and Reinvestment Act of 2009 (Recovery Act) grants totaling $19.4 million from the National Institutes of Health thus far. UCLA's largest NIH ARRA grant to date was $1.9 million, awarded to UCLA's Laboratory of Neuro Imaging (LONI), which is dedicated to creating scientific approaches to mapping how the brain is structured and how it works.
Lesbians, gays and bisexuals are twice as likely as heterosexual men and women to seek help from mental health professionals.
Scientists know that small, grape-like clusters of a protein called the amyloid β-protein are toxic, causing Alzheimer's (AD). By creating various sizes of clusters in the lab that exactly match what forms in AD brains, neurologists at UCLA have determined the toxicity of these clusters, and suggest a target for future drugs.
New research suggests that for seniors age 70 and older, socioeconomic status does not play a major role in the brain's continued ability to function. However, seniors who have never been married and widowers seem to perform more poorly as they age.
UCLA researchers have developed technology to perform more than a thousand chemical reactions at once on a stamp-size, PC-controlled microchip, which could accelerate the identification of potential drug candidates for treating diseases like cancer.
UCLA scientists have devised a new way to scan brain tumors and predict which ones will be shrunk by the drug Avastin -- before the patient ever starts treatment. By linking water movement in tumors to a positive drug response, researchers were able to predict with 70 percent accuracy which patients' tumors were least likely to grow six months after treatment.
Researchers found that 7 percent of fifth-graders and their families have experienced homelessness at some point in their lives and that the occurrence is even higher "” 11 percent "” for African American children and those from the poorest households. These children were significantly more likely to have an emotional, behavioral or developmental problem; were more likely to have witnessed serious violence with a knife or a gun; and were more likely to have received mental health care.
Children with autism spectrum disorders have great difficulty understanding emotions. For this reason UCLA researchers have developed a music education program designed to help children with ASD better understand emotions and learn to recognize emotions in others.
UCLA researchers have discovered the first genetic link to placebo: they report that in people suffering from Major Depressive Disorder, genes that influence the brain's reward pathways may modulate the response to placebos.
A UCLA study has identified a way to turn off a key signaling pathway involved in physiological processes that can also stimulate the development of cancer and other diseases. The findings may lead to new treatments and targeted drugs using this approach.
UCLA pioneered a new hybrid technique to treat aortic aneurysms in high-risk patients called CESA (combined endovascular and surgical approach). Since 1998, the procedure has been performed on 31 UCLA patients. In a recent issue of the Journal of Vascular Surgery, the UCLA surgical team reported excellent results in the first 20 high-risk patients with complex aortic pathology treated with CESA. The technique has been gaining popularity at centers throughout the world for high-risk cases.
UCLA scientists and colleagues from UC Riverside and the Human BioMolecular Research Institute have found that a form of vitamin D, together with a chemical found in turmeric spice called curcumin, may help stimulate the immune system to clear the brain of amyloid beta, which forms the plaques considered the hallmark of Alzheimer's disease.
UCLA scientists have discovered a way to measure the amount of amyloid beta that is being absorbed by immune cells in the blood. Amyloid beta forms the plaques considered the hallmark of Alzheimer's disease, and if the immune system isn't adequately clearing amyloid beta, it may indicate Alzheimer's risk, according to the researchers.
UCLA researchers have found that embryonic stem cells and skin cells reprogrammed into embryonic-like cells have inherent molecular differences, demonstrating for the first time that the two cell types are clearly distinguishable from one another.
Dr. Maria Ines Boechat, professor of radiology and pediatrics in the Department of Radiological Sciences at the David Geffen School of Medicine at UCLA, has been selected for the 2009-2010 class of fellows in the Hedwig van Ameringen Executive Leadership in Academic Medicine (ELAM) Program for Women at Drexel University College of Medicine.
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