Women with new-onset breast discomfort showed a 3.9 percent increase in breast density, compared with a 0.6 percent density increase in women who did not experience discomfort. As women with dense tissue face an increased cancer risk, new-onset discomfort during HRT may indicate a greater risk for developing breast cancer.
UCLA scientists have discovered that infants who possess a specific immune gene that too closely resembles their mothers' are more likely to develop schizophrenia later in life. Reported in the October issue of the American Journal of Human Genetics, the study suggests that the genetic match may increase fetal susceptibility to schizophrenia, particularly in females.
UCLA researchers have found the human gut to be a major reservoir harboring the HIV virus "” holding almost twice as much as a person's blood. In addition, the virus stored in the gut does not decay or reduce over time, as is also the case with blood-related reservoirs.
In contrast to traditional beliefs that stroke-causing clots derived from arterial and cardiac sources are distinctly different, a new study shows they are composed of similar components.
A new study shows that MRSA is the most common cause of skin and soft-tissue infections among patients presenting in emergency rooms across the country.
UCLA researchers found that altering the fatty acid ratio found in the typical Western diet to include more omega-3 fatty acids and decreasing the amount of omega-6 fatty acids may reduce prostate cancer tumor growth rates and PSA levels. This initial animal model study is one of the first to show the impact of lowering an inflammatory response known to promote prostate cancer tumor progression.
A unique nerve-stimulation treatment for epilepsy developed at UCLA offers a potential new alternative for tens of thousands of individuals unable to control their seizures with medication and ineligible for surgery. A study published in the July edition of the peer-reviewed journal Epilepsia reports that four of seven subjects who used an external stimulator for at least three months in a pilot human clinical trial enjoyed a 50 percent or better reduction in seizure frequency.
UCLA researchers have transformed adult stem cells taken from human adipose "“ or fat tissue "“ into smooth muscle cells, which help the normal function of a multitude of organs like the intestine, bladder, and arteries. The research may help lead to use of fat stem cells for smooth muscle tissue engineering and repair.
UCLA Investigators found that an experimental cancer drug improved signs of progeria in a new mouse model of progeria. The effects of the drug were more dramatic than in previous studies using other animal models.
With diabetes disease-management programs becoming more commonly used among physician groups, the question arises: Just how effective are they at improving patient care? The answer is that they lead to better examination and testing"”but not to better control of key factors associated with diabetes complications.
A new UCLA imaging study finds political party allegiance affects the brain activity of partisans viewing the faces of candidates. Published online July 9, 2006, by the peer-reviewed journal Neuropsychologia, the study finds a partisan's brain responds to the opposition candidate's face by activating cognitive networks designed to regulate emotion.
Researchers found that women who transmitted HIV to their offspring were significantly less likely to have aNAB, an antibody which neutralizes the virus, than non-transmitting mothers. This suggests that the antibody has a potent protective or selective effect in perinatal HIV transmission.
A UCLA-evaluated study of a demonstration project led by Community Health Councils, Inc. (CHC) in Los Angeles shows how incorporating physical activity and healthy eating into an office or other organizational culture pays dividends for participants.
Researchers report that thousands of genes behave differently in the same organs of males and females "“ something never detected to this degree. The study sheds light on why the same disease often strikes males and females differently, and why the genders may respond differently to the same drug.
Researchers from the UCLA AIDS Institute and the Institute for Stem Cell Biology and Medicine have demonstrated for the first time that human embryonic stem cells can be genetically manipulated and coaxed to develop into mature T-cells, raising hopes for a gene therapy to combat AIDS.
Drinking an eight ounce glass of pomegranate juice daily increased by nearly four times the period during which PSA levels in men treated for prostate cancer remained stable, a three-year UCLA study has found.
The Jules Stein Eye Institute will celebrate 40 years of excellence this month as a world-class facility for patient care, vision research and the training of future eye specialists. The center will commemorate its 40th anniversary with a gala dinner and research symposium at UCLA on May 19"“20.
Using novel 3-D mapping techniques to analyze MRI (magnetic resonance imaging) data from 20 patients with mild cognitive impairment, the researchers found that the patients with the smaller hippocampus face an increased risk of developing Alzheimer's dementia.
A new study found a shortage exists in the number of adults (non-students) who volunteer in academic hospitals.
Viral dynamics have an intrinsic periodicity, or cycle, varying from patient to patient. These forces interact with therapeutically prescribed, structured treatment interruptions (STI) in a way that causes high fluctuations in the patient's viral load and, ultimately, virologic failure.
Older men who drink as few as two drinks twice a week and also have diseases that could be worsened by alcohol or cause problems with medications taken while drinking alcohol have higher death rates, as compared to men who either drink less or may drink more but don't have such comorbidities.
Researchers have unraveled the molecular pathway that runs from sunlight to vitamin D to the body's critical ability to recognize and mount an immune defense against tuberculosis. The findings may also help explain why African American populations appear to be especially susceptible to the disease.
In the first study of its kind focusing on newly homeless youth, UCLA researchers have found that high-risk sexual behavior did not predict whether these youths were tested for sexually transmitted diseases. Instead, they were tested only when someone became pregnant or got someone pregnant.
In a recent clinical study researchers used a biosensor to identify correctly the infection-causing gram negative bacteria species in 98 percent of the tested clinical urinary tract infection urine samples.
UCLA has developed a new testing strategy to help manufacturers monitor and test the safety and health risks of engineered nanomaterials. Currently no government or industry regulations exist for this emerging technology.
Researchers developed a new brain imaging strategy that tracks neural cell loss in the hippocampus, a key memory center of the brain. This cell loss is a hallmark sign of Alzheimer's disease. This new imaging method may offer a new avenue for understanding disease progression as well as offer a new tool for early diagnosis of Alzheimer's disease.
Paper suggests that genetic, infectious and metabolic influences should be considered when looking for treatments, particularly in regard to HIV/AIDS.
Two new studies show that newborn screening for Severe Combined Immunodeficiency (SCID) "” a rare, treatable disorder of the immune system commonly known as "bubble boy disease" "” is both cost-effective and could be done accurately using a two tiered testing method.
A collaboration between scientists have developed a new technology using integrated microfluidics chips for simplifying, lowering the cost and diversifying the types of molecules used to image the biology of disease with the medical imaging technology, Positron Emission Tomography.
The first study of the effects of testosterone on mood, behavior and psychological health in men with mild Alzheimer disease finds significant improvements in quality of life, as assessed by caregivers. However, researchers found no significant differences in memory or other cognitive skills, as assessed by tests administered by clinicians.
Pairing the targeted therapy Herceptin with chemotherapy in patients with early stage breast cancer significantly increases disease-free survival time in women who test positive for a genetic mutation that results in a particularly aggressive form of the disease, according to large, international study.
In findings illustrating the difficulty of developing an AIDS vaccine, UCLA AIDS Institute researchers report the immune systems in two HIV-positive identical twins responded to the infection in different ways, showing that the body's defenses are random.
New imaging research shows children with autism have virtually no activity in a key part of the brain's mirror neuron system while imitating and observing emotions. Symptoms of autism include difficulties with social interaction.
A study spotlights benefits of psychotherapy for children and adolescents after a natural disaster. The study examined response by treated and untreated children following the 1988 Spitak earthquake, and has a lesson for responders to this year's string of natural disasters.
A UCLA/VA study found that irritable bowel syndrome (IBS) patients under age 50 who undergo a colonoscopy with normal results aren't reassured about their condition or seem to have an improved quality life due to the procedure ruling out a more serious condition.
A new study suggests the antidepressant bupropion may help treat methamphetamine addiction. No medications presently are approved for treating methamphetamine addicts.
Researchers found that infant mortality for black and white infants born at minority-serving hospitals, defined as hospitals where 35 percent of VLBW infants are black, was significantly higher than for black and white infants born at hospitals where fewer than 15 percent of these infants are black.
While the researchers noted that heavy drinking declined with age, they found it fell more slowly among men compared with women and among smokers compared with non-smokers.
An article pinpoints the breakdown of myelin -- the fatty insulation coating the brain's internal connections -- as an important component of childhood developmental disorders and addiction. This is the latest in a series of papers by George Bartzokis implicating myelin as a neural Achilles heel.
Researchers at UCLA's Jonsson Cancer have identified key characteristics in certain deadly brain tumors that make them 51 times more likely to respond to a specific class of drugs than tumors in which the molecular signature is absent.
HIV patients with a low socioeconomic status are likelier to die much more often than patients with higher levels of wealth and education, a new UCLA study has found. These findings are of concern given the high rates of HIV among patients with low socioeconomic status (SES).
Every dollar spent on substance abuse treatment generates $7 in monetary benefits for society, a new UCLA study shows. The study finds that the average $1,583 cost of substance abuse treatment is offset by monetary benefits such as reduced costs of crime and increased employment earnings totaling $11,487.
Researchers at UCLA's Jonsson Cancer Center have uncovered the mechanism by which an antibody blocks the growth of prostate cancer in animal models, a discovery that could pave the way for development of a new molecularly targeted therapy.
Harmful errors in teaching hospitals cost $13.2 billion each year nationwide. But the cost of reducing residents' hours by shifting work to other employees such as nurse practitioners and physician assistants would be much less, $673 million to $1.1 billion per year nationwide.
The study found that early detection and treatment of age-related macular degeneration with pegaptanib sodium (Macugen) may enable AMD patients to maintain and, in some cases, regain vision.
A UCLA/VA study found that for Hepatitis C patients who develop treatment-induced anemia due to a key medication, it is more cost-effective to take an additional drug to help prevent anemia, rather than reducing or stopping treatment altogether, which had been the standard approach.
The Fred H. Bixby Foundation has donated $5 million to the UCLA School of Public Health to expand the school's research, service and training in the fields of population and family planning.
A new study found that seniors with the lowest expectations for aging "”that is, for what one can do at an advanced age "” were the most likely to lead sedentary lifestyles.
Even though there are definitive guidelines to diagnose IBS through simple blood tests, many irritable bowel syndrome (IBS) patients have additional procedures and surgeries that rarely result in relief or any additional diagnostic findings.
The Division of Neurosurgery at UCLA Medical Center will present "Tonight Show" host Jay Leno with the first Rodney Respect award Oct. 20 at the division's inaugural Visionary Ball fundraiser in Beverly Hills.
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