Older men who drink as few as two drinks twice a week and also have diseases that could be worsened by alcohol or cause problems with medications taken while drinking alcohol have higher death rates, as compared to men who either drink less or may drink more but don't have such comorbidities.
Researchers have unraveled the molecular pathway that runs from sunlight to vitamin D to the body's critical ability to recognize and mount an immune defense against tuberculosis. The findings may also help explain why African American populations appear to be especially susceptible to the disease.
In the first study of its kind focusing on newly homeless youth, UCLA researchers have found that high-risk sexual behavior did not predict whether these youths were tested for sexually transmitted diseases. Instead, they were tested only when someone became pregnant or got someone pregnant.
In a recent clinical study researchers used a biosensor to identify correctly the infection-causing gram negative bacteria species in 98 percent of the tested clinical urinary tract infection urine samples.
UCLA has developed a new testing strategy to help manufacturers monitor and test the safety and health risks of engineered nanomaterials. Currently no government or industry regulations exist for this emerging technology.
Researchers developed a new brain imaging strategy that tracks neural cell loss in the hippocampus, a key memory center of the brain. This cell loss is a hallmark sign of Alzheimer's disease. This new imaging method may offer a new avenue for understanding disease progression as well as offer a new tool for early diagnosis of Alzheimer's disease.
Paper suggests that genetic, infectious and metabolic influences should be considered when looking for treatments, particularly in regard to HIV/AIDS.
Two new studies show that newborn screening for Severe Combined Immunodeficiency (SCID) "” a rare, treatable disorder of the immune system commonly known as "bubble boy disease" "” is both cost-effective and could be done accurately using a two tiered testing method.
A collaboration between scientists have developed a new technology using integrated microfluidics chips for simplifying, lowering the cost and diversifying the types of molecules used to image the biology of disease with the medical imaging technology, Positron Emission Tomography.
The first study of the effects of testosterone on mood, behavior and psychological health in men with mild Alzheimer disease finds significant improvements in quality of life, as assessed by caregivers. However, researchers found no significant differences in memory or other cognitive skills, as assessed by tests administered by clinicians.
Pairing the targeted therapy Herceptin with chemotherapy in patients with early stage breast cancer significantly increases disease-free survival time in women who test positive for a genetic mutation that results in a particularly aggressive form of the disease, according to large, international study.
In findings illustrating the difficulty of developing an AIDS vaccine, UCLA AIDS Institute researchers report the immune systems in two HIV-positive identical twins responded to the infection in different ways, showing that the body's defenses are random.
New imaging research shows children with autism have virtually no activity in a key part of the brain's mirror neuron system while imitating and observing emotions. Symptoms of autism include difficulties with social interaction.
A study spotlights benefits of psychotherapy for children and adolescents after a natural disaster. The study examined response by treated and untreated children following the 1988 Spitak earthquake, and has a lesson for responders to this year's string of natural disasters.
A UCLA/VA study found that irritable bowel syndrome (IBS) patients under age 50 who undergo a colonoscopy with normal results aren't reassured about their condition or seem to have an improved quality life due to the procedure ruling out a more serious condition.
A new study suggests the antidepressant bupropion may help treat methamphetamine addiction. No medications presently are approved for treating methamphetamine addicts.
Researchers found that infant mortality for black and white infants born at minority-serving hospitals, defined as hospitals where 35 percent of VLBW infants are black, was significantly higher than for black and white infants born at hospitals where fewer than 15 percent of these infants are black.
While the researchers noted that heavy drinking declined with age, they found it fell more slowly among men compared with women and among smokers compared with non-smokers.
An article pinpoints the breakdown of myelin -- the fatty insulation coating the brain's internal connections -- as an important component of childhood developmental disorders and addiction. This is the latest in a series of papers by George Bartzokis implicating myelin as a neural Achilles heel.
Researchers at UCLA's Jonsson Cancer have identified key characteristics in certain deadly brain tumors that make them 51 times more likely to respond to a specific class of drugs than tumors in which the molecular signature is absent.
HIV patients with a low socioeconomic status are likelier to die much more often than patients with higher levels of wealth and education, a new UCLA study has found. These findings are of concern given the high rates of HIV among patients with low socioeconomic status (SES).
Every dollar spent on substance abuse treatment generates $7 in monetary benefits for society, a new UCLA study shows. The study finds that the average $1,583 cost of substance abuse treatment is offset by monetary benefits such as reduced costs of crime and increased employment earnings totaling $11,487.
Researchers at UCLA's Jonsson Cancer Center have uncovered the mechanism by which an antibody blocks the growth of prostate cancer in animal models, a discovery that could pave the way for development of a new molecularly targeted therapy.
Harmful errors in teaching hospitals cost $13.2 billion each year nationwide. But the cost of reducing residents' hours by shifting work to other employees such as nurse practitioners and physician assistants would be much less, $673 million to $1.1 billion per year nationwide.
The study found that early detection and treatment of age-related macular degeneration with pegaptanib sodium (Macugen) may enable AMD patients to maintain and, in some cases, regain vision.
A UCLA/VA study found that for Hepatitis C patients who develop treatment-induced anemia due to a key medication, it is more cost-effective to take an additional drug to help prevent anemia, rather than reducing or stopping treatment altogether, which had been the standard approach.
The Fred H. Bixby Foundation has donated $5 million to the UCLA School of Public Health to expand the school's research, service and training in the fields of population and family planning.
A new study found that seniors with the lowest expectations for aging "”that is, for what one can do at an advanced age "” were the most likely to lead sedentary lifestyles.
Even though there are definitive guidelines to diagnose IBS through simple blood tests, many irritable bowel syndrome (IBS) patients have additional procedures and surgeries that rarely result in relief or any additional diagnostic findings.
The Division of Neurosurgery at UCLA Medical Center will present "Tonight Show" host Jay Leno with the first Rodney Respect award Oct. 20 at the division's inaugural Visionary Ball fundraiser in Beverly Hills.
First identified more than 20 years ago at UCLA, defensins are peptides naturally produced by the immune system to ward off viruses. However, it was unclear how defensins worked. Now UCLA and NIH scientists have discovered that a specific defensin called retrocyclin-2 (RC2) binds to carbohydrate-containing proteins in cell membranes.
UCLA experts are available to describe the challenges facing forensic pathologists in identifying casualties, and to discuss the public health, psychological, economic and structural/rebuilding effects of Hurricane Katrina.
Patients with a cervical spine injury may harbor additional spinal damage not visible on regular x-rays. Researchers found more than a third of patients who were thought to have low-risk injuries actually have additional damage that may include significant fractures with the potential to produce serious spinal problems if not detected and treated properly.
Treatment with a statin drug within the first 24-hours after a heart attack reduced in-hospital mortality rates by over 50 percent according to a new UCLA study.
The Integrated Substance Abuse Programs at the Jane and Terry Semel Institute for Neuroscience and Human Behavior at UCLA will convene a four-day meeting of health officials from more than two dozen Middle East nations and their neighbors Sept. 4"“8 in Istanbul, Turkey.
Investigators examining responses to cocaine and methamphetamine use find distinct differences in onset, pattern and duration. Subjective, or self-reported, responses to cocaine peak and decline more rapidly than those of methamphetamine, the study shows.
In findings that could lead to curing some forms of congenital blindness through gene therapy, researchers at UCLA have discovered that RPE65, a gene missing in infants born with the blinding disease Leber congenital amaurosis, is also a key enzyme in the visual cycle.
Functional MRI has become a preferred method for measuring brain activity in research and clinical work, but until now no one has actually correlated real brain electrical activity to blood flow activity measured by fMRI. Neuroscientists at UCLA and the Weizmann Institute are the first.
A product produced by lung cancer tumors fuels the cells that suppress immune function in patients and may be a target for Celebrex therapy, giving oncologists another weapon to fight cancer, according to a study by researchers at UCLA's Jonsson Cancer Center.
UCLA investigators found large gaps and variations in treatment for heart failure in U.S. hospitals based on four standard quality measures. Performance of these measures is closely linked to heart failure patients' risk of rehospitalization and death.
UCLA scientists have discovered how the deadly Nipah virus infiltrates human cells to cause encephalitis. Designated as a potential bioterrorism agent by the National Biodefense Research Agenda, the virus exploits a protein essential to embryonic development to enter cells and launch its attack.
A multi-site research group working under contract with NIMH finds that risperidone, one of the newer anti-psychotic medications, is safe and effective for controlling aggressive and violent behavior in autistic children with minimal side effects for up to six months.
A study finds that unlike other mammals, newborn dolphins and killer whales remain awake and active 24/7 during the first weeks of life when critical development takes place.
Medical residents in Japan are more likely to involve patients' families in end-of-life decision making -- and to favor informing family members over the patients first -- than their United States counterparts, who prefer dealing directly with the patient.
UCLA and Caltech researchers report that single brain cells are much more powerful than previously thought. Single neurons are able to distinguish people, such as actress Halle Berry, places and things, and recognize them in varying contexts and even abstract form.
Researchers discovered that some patients with Alzheimer's disease have an immune system defect making it difficult to clean away amyloid-beta waste products in the brain. This may lead to over-saturation of the brain with amyloid beta, which form amyloid plaques, the definitive hallmark of Alzheimer's disease.
A randomized study found that a new dosing paradigm can improve height outcomes in the treatment of children who have short stature due to growth hormone deficiency and idiopathic short stature.
Writing in the upcoming edition of Neuron, researchers pinpoint the electrical "signature" of hypocretin brain cells, whose loss triggers narcolepsy, and find these cells are active during excitement generated by positive emotions and play a key role in maintaining brain alertness.
Amid the debate over which combination of immunosuppressive agents works best in helping patients fight off rejection of their new heart after transplant surgery, a new study showed that one particular combination using tacrolimus had significant anti-rejection benefits for heart transplant patients over other combinations.
Being married or in a relationship significantly improves quality of life for prostate cancer patients following treatment, according to a study by researchers at UCLA's Jonsson Cancer Center and the Department of Urology.
RSS
Medicine keyboard_arrow_right
Sciencekeyboard_arrow_right
Life keyboard_arrow_right
Business keyboard_arrow_right
Journal News keyboard_arrow_right
By Location keyboard_arrow_right
Meetings, Grants, and Events keyboard_arrow_right