A dietary staple of India holds potential as a weapon in the fight against Alzheimer's. The study involving genetically altered mice suggests that curcumin, the yellow pigment in curry spice, inhibits the accumulation of destructive beta amyloids in the brains of Alzheimer's patients and also breaks up existing plaques.
Researchers at UCLA's Jonsson Cancer Center have identified for the first time a way to predict which prostate cancer patients will benefit from an experimental therapy that blocks a cell signaling pathway responsible for driving the growth of the cancer.
Findings suggest that individuals with high overall cardiovascular risk in midlife can be identified by relatively higher risk factors when they are younger and that young people from families with a lower SES experienced greatest increases in those risk factors.
Researchers find that depressed and highly anxious Mexican-Americans with a variant of the CRH gene had a 70 percent greater reduction in anxiety and a 30 percent greater reduction in depression in response to two anti-depressants.
In one of the first studies using the RNA in saliva to detect cancer, researchers were able to differentiate head and neck cancer patients from a group of healthy subjects based on biomarkers found in their spittle.
Using animal models and human tissue, a UCLA/VA research team 1) identified a shortfall of IDE protein in the brains of Alzheimer's disease patients; 2) found a cause-effect relationship between insulin signaling and increased production of IDE, and 3) demonstrated that a low-fat diet high in fish and soy can increase production of IDE.
A new study reports higher arrest rates among drug offenders diverted to treatment during the first six months of California's Substance Abuse and Crime Prevention Act, commonly known as Proposition 36.
A new UCLA study shows that African-American HIV patients treated by white doctors receive life-saving HIV medication less than those who have an African-American doctor.
A new UCLA and University of Utah study found how a hormone called hepcidin regulates the iron uptake from the diet and its distribution in the body. The study may help develop future treatments for chronic anemia and for diseases of iron overload, such as hemochromatosis.
UCLA Medical Center nurse Lance Patak has cared for many critically ill patients who couldn't communicate their needs due to endotracheal tubes. So he developed an easy-to-use communication board for them.
New projections showing the impact of Alzheimer's disease locally and nationally, as well as how simple lifestyle changes could lower disease incidence will be presented at the first Annual Aging Forecast at UCLA. Featuring national Alzheimer's disease experts.
New UCLA research suggests that a diet rich in the omega-3 fatty acid DHA may lower one's risk of Alzheimer's disease and help slow progression of the disorder in its later stages.
While nearly three-quarters of Americans believe that the public health system would respond fairly in a bioterrorist event, African-Americans and Asians adhere to this view in smaller proportions, perhaps because of past discriminatory policies put in place by health officials.
Seniors who use up their yearly drug benefits before the end of the year often resort to reducing their recommended dosages, or even stop taking their medications altogether"”a situation that could endanger their health, according to a UCLA study.
Researchers for the first time identified and then stopped a type of adult stem cell from migrating to the lung and contributing to pulmonary fibrosis in an animal model. Pulmonary fibrosis is a devastating terminal disorder that causes an overabundance of scar tissue in the lung.
An experimental therapy that may battle resistance to the drug Gleevec in patients with chronic myeloid leukemia has shown promising results in a study at UCLA's Jonsson Cancer center, increasing survival in animal models and perhaps paving the way for a second generation targeted therapy.
For the first time, researchers have recreated the ability of mammalian cells to self-organize, forming evenly spaced patterns in a test tube. The findings may help improve methods for regenerating tissue, controlling birth defects and developing new treatments for specific diseases.
Detailed results of the National Survey of Early Childhood Health finds that while many parents are generally satisfied with the quality and content of care provided by physicians caring for young children during well visits, critical areas of health care and development are not being addressed for some children.
A drug designed to cut off a tumor's blood supply, when paired with a chemotherapy combination, resulted in significant improvement in survival in patients with metastatic colorectal cancer, the first time in decades that survival times have been extended in patients with this devastating form of advanced cancer.
Moderate exercise and common dietary supplements significantly reduce the risk of atherosclerosis because, combined, they boost the body's production of nitric oxide, which protects against a variety of cardio-vascular disorders.
A pair of studies at UCLA's Jonsson Cancer Center taking laboratory science to the patient bedside found that combining the molecularly targeted therapy Herceptin with a specific chemotherapy combination resulted in significant tumor response rates and longer relapse-free periods in women with an aggressive form of advanced breast cancer.
Researchers identify the key factor that triggers a chain reaction causing low iron and anemia in patients with infections and major inflammatory diseases. The study may help target new interventions to help prevent anemia in patients with specific inflammatory diseases.
A new study shows how communication techniques between a doctor and parents can result in increased parental satisfaction with the treatment plan for their child's upper respiratory illness and avoid unnecessary antibiotic prescriptions.
Using CT images to steer gene-therapy injections into tumors offers a safe delivery route for treating patients with metastatic kidney cancer, report radiologists. The disease resists intravenous chemotherapy in 85 percent of cases.
A new study shows that 'time matters' when treating fungal infections in neonates and that earlier treatment can mean the difference between life and death.
A new study finds that doctors who follow guidelines recommending the delay of antiretroviral therapy for non-adherent HIV patients are likelier to put off that treatment for Latinos, women, and poor patients than they do for others.
New findings at the Neuropsychiatric Institute demonstrate the potential of a substance found in yohimbe tree bark to accelerate recovery from anxiety disorders suffered by millions of Americans.
Long-term, 18-month clinical trial results confirm a new drug's effectiveness in halting progression of type 1 diabetes and improving a diabetic's ability to produce insulin. Findings will be announced at the International Diabetes Society meeting in Cambridge, England.
A new study shows that patients with pulmonary fibrosis were four times more likely to have extensive coronary artery disease than patients without this lung condition. The study may lead to a greater understanding of both diseases. This is the first study of its kind.
Dr. Dennis Slamon, whose laboratory and clinical research led to the development of the molecularly targeted breast cancer drug Herceptin, has been named to receive the highest honor the American Cancer Society bestows on scientists.
Medication, diet, exercise and other lifestyle choices common to good heart health could promote healthier brains as well.
Statin medications may significantly improve survival of heart failure patients. A study shows that statin usage reduced mortality rates by an impressive 55 percent --regardless of patients' cholesterol levels or reason for heart failure.
A low-fat diet may help men with aggressive prostate cancer better fight their disease and live longer, according to researchers who showed that a diet low in polyunsaturated fats slowed cancer growth and increased survival times in lab models.
As new economic reforms and opportunities unfold in China's cities, researchers find that urban adolescent boys may be rethinking the importance of adhering to centuries-old family obligations.
Researchers found that volunteers who lacked a particular antioxidant-producing gene, called GSTM1, had a greater allergic response when exposed to diesel particles and ragweed. According to researchers, up to 50 percent of the U.S. population does not have this particular gene.
Researchers have used PET imaging to pinpoint symptoms of depression and anxiety in Meth Users during the first days of therapy. Left unaddressed, these symptoms can undermine the success of treatment.
UCLA/USC researchers have linked a variation of a gene called 5-LO to an increased risk for atherosclerosis, or thickening of the arteries. The discovery soon may enable physicians to test for modified 5-LO as a marker for heart attack and stroke.
A scientist has used imaging analysis to pinpoint the midlife breakdown of myelin -- a fatty substance that insulates the brain's internal wiring "“ as a key to the onset of Alzheimer's disease later in life. His model opens numerous potential avenues for prevention.
UCLA AIDS Institute scientists have identified the immune mechanism that makes introverts more susceptible than extroverts to HIV and other viruses. The difference lies in their body's response to stress.
The anti-spasticity medication baclofen holds promise for helping cocaine abusers overcome their addiction, a study finds. No medication currently holds U.S. Food and Drug Administration approval for treatment of cocaine addiction.
The UCLA Neuropsychiatric Century. The fellowship is being organized in conjunction with the Council for the Advancement and Support of Education (CASE).
The UCLA Integrated Substance Abuse Programs (ISAP) has published a detailed report on the effectiveness and findings of an automated system for measuring drug abuse treatment results during a pilot test in 13 California counties.
Men with high risk prostate cancer who are candidates for surgery are being sought to test a molecularly targeted experimental drug that may interrupt the signal that is driving their cancer and keep the disease from recurring.
Researchers at UCLA's Jonsson Cancer Center have discovered that brain tumors may be derived from the cells that form the nervous system, called neural stems cells, which may help them understand how this cancer begins and could one day lead to improved diagnosis and treatment.
An unprecedented test may offer a better way to diagnose heart disease risk for patients who develop coronary heart disease despite normal cholesterol levels. Testing the inflammatory and/or anti-inflammatory properties of a patient's HDL may be a more accurate way of predicting heart disease risk.
Leading-edge experimental cancer treatments will be provided to an under-served, minority patient population in South Central Los Angeles under a new partnership between UCLA's Jonsson Cancer Center and Charles R. Drew University of Medicine and Science, cancer center officials announced.
A new study shows that patients with SARS are more than twice as likely to die from the disease if they come from areas of high pollution.
UCLA researchers found improvement in verbal recall among a group of people with age-associated memory impairment who took the ginkgo biloba for six months compared with a group who took a placebo.
To explore these increasingly complex issues, UCLA Healthcare has created the UCLA Healthcare Ethics Center. The center's mission is to provide education, service and research to enhance the practice of medicine for patients, families, professionals and the public.
Scanning a patient's brain metabolism with PET can improve a doctor's ability to forecast the patient's future cognitive functions up to 30 percent. The findings suggest that PET may offer physicians a new tool to help with earlier diagnosis and treatment of Alzheimer's disease.
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