UCLA researchers have determined that too much of a human sex gene can convert an embryo from male to female, often resulting in ambiguous genitalia. The findings offer new hope for parents whose babies are born with genital malformations -- and valuable diagnostic information for physicians who make decisions about the newborn's gender.
The lung cancer program at UCLA's Jonsson Cancer Center has been designated a Specialized Program of Research Excellence by the National Cancer Institute, making it one of six programs nationwide to receive national recognition and substantial research funding.
UCLA physicians announced that three young boys - each born with a defective immune system like the "boy in the bubble" - underwent umbilical-cord blood transplants from unrelated donors, and two years later, are seemingly cured of their immunodeficiencies. (Journal of Pediatrics, 4-01)
An experimental pill for a common form of adult leukemia continues to show great promise in early studies. (NEJM, 4-5-01)
UCLA AIDS Institute researchers solve mystery of how HIV exploits the human immune system to hibernate and avoid anti-AIDS drugs -- then resurface years after initial infection. (Nature Medicine, 3-01)
A UCLA study finds that HIV-infected youth participating in an AIDS- intervention program willingly cut their high-risk sex by 82 percent and lowered their drug use by a third. (Am. J. of Public Health, 3-01)
For the second consecutive year, scientists at UCLAÃs Jonsson Cancer Center have earned more CaP CURE prostate cancer research awards than any other single institution nationwide. In all, 10 UCLA scientists will receive grants this year totaling more than $1 million.
A new molecular imaging center that will develop innovative ways to see gene-based therapies at work in the human body was launched at UCLA's Jonsson Cancer Center. The $9.8M UCLA Center for In Vivo Imaging in Cancer Biology is the first such molecular imaging center on the West Coast.
An experimental targeted therapy for chronic myelogenous leukemia continues to show promise in early testing, and it may help to battle the disease even at its most aggressive and deadly stage, according to a researcher at UCLA's Jonsson Cancer Center.
Athletes hoping to boost their performance by consuming an over-the-counter dietary supplement known as "andro" may actually increase their risk of testing positive for banned steroid use.
For 7-year-old Kyle Schepens - near death due to a virulent form of heart disease - a new and surprisingly hopeful treatment allowed him to celebrate his eighth birthday. (Heart and Lung Transplantation, 11-00)
Scientists from UCLA and the University of Cambridge, United Kingdom, report a revolutionary advance in pain medicine that promises to deliver painkillers directly to the affected area of the body, in smaller doses and with fewer side effects.
New research suggests that adding an experimental drug to antiviral therapy may help persons with advanced HIV infection rebuild their immune systems faster than antiviral therapy alone.
For parents worried about the consequences of concussion in their children, a new UCLA study suggests that mild traumatic brain injury may impair a child's brain's ability to develop to its fullest potential.
In an effort to shed light on a largely unexplored disease and provide more effective treatments, officials from UCLA's Jonsson Cancer Center today launched a state-of-the-art liver cancer center.
UCLA AIDS Institute researchers have found that HIV may have an easier time penetrating and replicating itself through the gut than the circulatory system, explaining why unprotected oral and anal sex with an infected partner holds even greater risk than previously believed (AIDS).
UCLA's Jonsson Cancer Center scientists have discovered a novel way to follow gene therapy through the body. The technology essentially renders the body transparent and will allow physicians to determine whether gene therapies reach targeted cells and work as they should (Nature Medicine, 8-1-00).
Breast cancer survivors with severe menopausal symptoms can find significant relief through a comprehensive program that emphasizes supportive care in addition to medication, according to a study by UCLA's Jonsson Cancer Center researchers (Journal of the National Cancer Institute, 7-5-00).
Without leaving their own neighborhoods, prostate cancer patients in five Southern California counties can get experimental treatments they otherwise could not receive. Urologists in this area now offer leading-edge clinical trials, many of which are only available through UCLA's Jonsson Cancer Center.
The first non-invasive method to deliver therapeutic genes to the brain -- an innovation that could help millions of people suffering from Parkinson's disease, brain cancer and AIDS, as well as genetic disorders like Tay-Sachs and Gaucher's disease -- has been created by UCLA researchers (Proceedings of the National Academy of Sciences, 6-5-00).
An article published in today's New England Journal of Medicine from researchers at UCLA reports that nearly 90 percent of young adults undergoing dialysis had signs of coronary artery calcification and that in most patients, the amount of calcification doubled within two years.
A UCLA study on children born with heart disease showed that when comparing the child's age at surgical repair, children with private insurance underwent surgery at a younger age than children with managed care health plans (Pediatrics, 5-00).
For the 500,000 Americans suffering from arm and neck pain caused by a herniated disc or bone spur in the neck, an improved microsurgical technique developed by UCLA neurosurgeons may bring them the relief they seek (Spine, 4-00).
A way to increase the number and function of rare and powerful immune system cells inside the human body has been discovered by Jonsson Cancer Center researchers (Cancer Research, 4-1-00).
That early injury to the human brain due to a stroke can be reversed by rapidly reopening blocked blood vessels with clot-busting drugs has been demonstrated by UCLA researchers; all patients in their study showed dramatic improvement (Annals of Neurology, 4-00).
Dennis Slamon, whose research led to the development of the drug Herceptin, will be honored Tuesday (March 21) in San Diego for his work leading to the breakthrough breast cancer treatment.
UCLA's Heart Transplant Program, the largest in the U.S., reached a landmark 1,000 heart transplants performed, on March 8, 2000.
A study in the March 6 Health Affairs raises questions about possible adverse impacts of slick ads for prescription medications on clinical care; do the ads serve the promotional interests of drug companies at the expense of public health needs.
A new tool designed to help emergency medical services personnel accurately detect potential stroke patients in the field has proved 91 percent accurate, reports a UCLA Stroke Center study; other U.S. cities are encouraged to use this new stroke survey to help save more lives (Stroke, 1-00).
For children born with chest wall deformities, a new UCLA study shows that surgical intervention can improve their long-term health, with excellent physical and cosmetic results and a low complication rate.
In a study focusing on ill children and adolescents with depressed immune systems, UCLA's Jonsson Cancer Center researchers will try to determine if laughter can help reduce pain and prevent and treat diseases.
UCLA researchers report, for the first time, that smoking marijuana may increase the risk of head and neck cancers. Results of an epidemiological study of more than 340 people are outlined in an article published in the Dec. 17 edition of the journal Cancer Epidemiology Biomarker and Prevention.
One-third of the nation's HIV patients say they have either gone without or postponed medical care because they needed to attend to life necessities, according to researchers from UCLA, RAND and other institutions.
Researchers at UCLA's Jonsson Cancer Center are seeking patients with chronic myelogenous leukemia to participate in a study of a new experimental drug that has resulted in dramatic responses in some patients in early testing.
UCLA researchers have identified for the first time the very small section of the brain thought to control breathing in mammals, they report in the Nov. 19 edition of Science.
Regulating automobiles as a consumer product has reduced injuries and deaths from vehicle collisions. Now there is increasing evidence that the public supports the same sort of regulatory approach to firearms as a means to cut injuries and death from guns, UCLA researchers report in the Nov. 19 edition of Science.
The nation's leaders in the effort to develop an HIV vaccine and put at end to the worldwide AIDS epidemic will share the latest breakthroughs at the UCLA AIDS Institute's Scientific Symposium on Nov. 19.
Researchers at UCLA's Jonsson Cancer Center are seeking long-term adult cancer survivors for a first-of-its-kind study to gather information on the physical and psychological effects of cancer long after diagnosis and treatment.
Scientists at UCLA's Jonsson Cancer Center, working to define the genetic profile of AIDS-related lymphomas, have identified a gene they believe may be linked to non-Hodgkin's lymphoma in AIDS patients.
A team of UCLA scientists has discovered two human proteins that inhibit the formation of new blood vessels and have potential for treating cancer through suppression of tumor growth.
HIV-infected women often fail to receive diagnosis or medical care because they do not fit clinicians' cultural stereotypes regarding who is at risk.
Aggressive surgery coupled with strong immunotherapy resulted in significantly increased survival times for a group of advanced kidney cancer patients for whom few other treatment options existed, according to researchers at UCLA's Jonsson Cancer Center.
An experimental genetic treatment has yielded promising results for some women whose disease failed to respond to conventional treatments, according to a preliminary study at UCLA's Jonsson Cancer Center.
The human thymus -- the organ that produces the immune system's infection-fighting T cells -- remains functional until at least age 56, UCLA AIDS Institute investigators have proved for the first time.
Promising results for a vaccine to treat brain cancer in preliminary studies at UCLA's Jonsson Cancer Center was reported in the cover-story published in the June 1 issue of the Journal of Neurosurgery.
Five Los Angeles-area health centers will be among 400 sites to offer a drug that may reduce the risk of breast cancer in postmenopausal women. The Study of Tamoxifen and Raloxifene, or STAR, is one of the largest breast cancer prevention studies ever conducted, and will involve 22,000 women at sites in the United States, Canada and Puerto Rico.
Owning a pet may reduce the likelihood that men with AIDS will suffer from depression, according to a study by researchers at the UCLA School of Public Health.
Adults who suffer from obstructive sleep apnea are three times more likely to also have diabetes, according to a new UCLA School of Dentistry/Department of Veterans Affairs study published in the Journal of Oral and Maxillofacial Surgery.
Children who live through catastrophic events develop an advanced understanding of right and wrong, but they may not act morally because the trauma disrupts their view of the world, according to researchers from the UCLA School of Medicine.
Researchers at UCLA's Jonsson Cancer Center today are launching a new experimental treatment for advanced colon cancer, using a drug thought to attack tumors by cutting off their blood supply. UCLA is the only site worldwide offering this experimental treatment for colon cancer, researchers said.
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