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The researchers found the cancer cells that survive the first round of radiotherapy or chemotherapy do so by mutating during the post-treatment minimal residual disease (MRD) or dormant state.
A McMaster University-led has found that most people infected with the SARS-CoV2 virus recover within 12 months, irrespective of the severity.
The global study assessed risk factors, including metabolic (such as high blood pressure, obesity and diabetes), behavioural (smoking and diet), and psychosocial (economic status and depression) in about 156,000 people without a history of CVD between the ages of 35 and 70. Living in 21 low, middle and high-income countries on five continents, they were followed for an average of 10 years.
Whitney and Bullen, together with colleagues at Imperial College London and the University of Manitoba, have studied this toxin for nearly three years to understand exactly how it functions at a molecular level. The breakthrough, to be published in Molecular Cell, was achieved by Bullen following rigorous experimentation on common targets of toxins, such as protein and DNA molecules, before eventually testing the toxin against RNA. This discovery breaks well-established precedents set by protein-targeting toxins secreted by other bacteria, such as those that cause cholera and diphtheria.
A modern scientific analysis of ancient stone tools is challenging long-held beliefs about what caused radical change on the island of Crete, where the first European state flourished during the Bronze Age: the ‘Minoan civilization.’
In this study published in the Canadian Journal of Emergency Medicine, changes in annual paramedic transports in the ten years prior to the COVID-19 pandemic were examined. Patients triaged in the ED who arrived by paramedics or walk-in were included and clustered by geographical region.
Researchers at McMaster University have found a class of well-known antiviral drugs could be part of a one-two punch to treat seasonal influenza and prevent a flu pandemic when used in combination with antibody therapies.
McMaster researchers create device to replicate conditions in blood vessels after grafts
The authors conducted a population-based cohort study including 1,951,984 deliveries in Sweden and British Columbia, Canada, from 2004 to 2016, with data obtained from national and provincial birth registers. They assessed differences in caesarean delivery rates between countries and over time using the WHO-endorsed caesarean delivery classification. They compared these differences in caesarean delivery rates with and without accounting for population differences in maternal, fetal, and obstetric practice factors, such as maternal age, maternal body-mass-index, fetal weight and fetal position.
Researchers at Canada's McMaster University have discovered a significant and previously unknown mechanism that many bacteria use to resist antibiotics.
The McMaster-Queen’s research team pinpointed the bacterium Klebsiella aerogenes as the key histamine producer by studying germ-free mice colonized with gut microbiota from patients with IBS. They also colonized some mice with gut microbiota from healthy volunteers as a control group. The study found that the bacterium Klebsiella aerogenes converts dietary histidine, an essential amino acid present in animal and plant protein, into histamine, a known mediator of pain.
Moderna vaccines are better than Pfizer in protecting residents of long-term care (LTC) homes from COVID-19 Omicron infections, say McMaster University researchers.
People with mild or moderate eczema may gain some relief from their condition by adjusting their diets, but there are important downsides that make diets for eczema not a choice to take lightly, says McMaster University researcher Derek Chu.
Iodine deficiency, a public health concern resolved decades ago, may be making a comeback due to changing eating habits, according to new findings by McMaster University researchers.
A COVID CommUNITY – South Asian study, published in the Canadian Medical Association Journal (CMAJ) Open has found that South Asian communities living in the Greater Toronto Area (GTA) suffered disproportionately from COVID-19 in the first year of the pandemic.
Researchers at McMaster University have unlocked an evolutionary mystery of a deadly pathogen responsible for fueling the superbug crisis: it can reproduce by having sex.
New drugs and technologies covered by insurance plans can be much more profitable than those not covered, which may lead to bias in CEAs funded by pharmaceutical or other medical industry firms. The research team gleaned its data by analysing the results of more than 8,000 CEAs published between 1976 and March 2021. Nearly 30 per cent of these CEAs were sponsored by industry.
An international team led by researchers at McMaster University, working in collaboration with the University of Paris Cité, has identified and reconstructed the first ancient genome of E. coli, using fragments extracted from the gallstone of a 16th century mummy.
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