Researchers have discovered the presence of functional ion channels in human embryonic stem cells. These ion channels act like electrical wires and permit ESCs, versatile cells that possess the unique ability to become all cell types of the body, to conduct and pass along electric currents.
A Johns Hopkins emergency physician who spent the past five weeks working on public health issues in the Gulf Coast region following hurricane Katrina warns that the disaster's potential for wreaking havoc and damage to people's health may continue for months after the hurricane has passed.
Some newer antipsychotic medications may be associated with a small increased risk of death when used to treat elderly dementia patients, psychiatrists at Johns Hopkins warn.
A Johns Hopkins infectious disease expert will lead two international studies of the effectiveness of the antibiotic moxifloxacin as a new treatment for tuberculosis, the highly contagious bacterial disease that kills more than 2 million people worldwide each year and is the leading cause of death of people living with HIV and AIDS.
A Johns Hopkins study has affirmed the success of living kidney "paired donation" (KPD) as a means of efficiently finding more kidney donors who are a match for patients in need.
Researchers have linked alterations in a gene, called Rsf-1, to the most deadly ovarian cancers. The scientists say the discovery is the first to establish a role for the gene in ovarian cancer and may lead to a test that can predict, early on, which patients will develop aggressive disease.
Heart specialists at Johns Hopkins Heart Institute have been awarded more than $12 million from the National Heart, Lung, and Blood Institute (NHLBI) to study how stem cell therapies can be used to treat hearts damaged by heart attack or heart failure.
Johns Hopkins scientists have discovered that a drug currently being tested against cancers might help children with a rare, fatal condition called Hutchinson-Gilford progeria syndrome, which causes rapid, premature aging.
Researchers have identified three new genetic mutations in brain tumors, a discovery that could pave the way for more effective cancer treatments. The team discovered DNA abnormalities in two tyrosine kinase proteins already known to disrupt normal cell activity and contribute to tumor formation.
More than one-half of 631 physicians tested were unable to correctly diagnose diseases caused by agents most likely to be used by bioterrorists, such as smallpox, anthrax, botulism and plague, according to a Johns Hopkins study.
Hopkins researchers have discovered a single molecule that is a cause of an autoimmune disease in the central nervous system, called transverse myelitis (TM), that is related to multiple sclerosis.
Scientists have discovered internal "shipping labels" that allow hundreds if not thousands of proteins to get to the surface of cells and stay there. Two natural proteins that use one of these "tags" are the ion channel that lets heart cells contract on cue, and the docking point that allows HIV, the virus that causes AIDS, into cells.
Cardiology experts at Johns Hopkins have issued interim guidelines for physicians on how best to treat low levels of HDL cholesterol, the so-called good cholesterol, which helps keep arteries clear from the buildup of LDL cholesterol, the so-called bad cholesterol.
Johns Hopkins scientists have discovered that a deceptively simple sugar is in fact a critical regulator of cells' natural life cycle.
Physicians at The Johns Hopkins Hospital have disproved the notion that longer hospital stays mean better care. They have successfully cut back on wait times across one dozen hospital departments and, as a result, reduced to well below six the average number of days patients with congestive heart failure, a need for dialysis or surgery.
Scientists have identified a molecular pathway in mice that makes prostate cells vulnerable to cancer-causing oxygen damage. The pathway, which is also involved in human prostate cancer, may help determine how and whether antioxidants can prevent prostate cancer.
Performing cardiac stress tests that measure exercise capacity and heart rate recovery can improve dramatically on existing techniques that predict who is most likely to suffer a heart attack or die from coronary heart disease, the leading cause of death in the United States.
In a study from Johns Hopkins, a pocket-size device giving electronic-voice reminders to "take your medicine" proves to be a success for people living with HIV whose memory is slightly impaired by the virus.
Despite recent claims by some urologists that measuring the blood protein prostate-specific antigen may not be effective in predicting risk of prostate cancer, a study of more than 2,000 men confirms that PSA remains the best measure of the likelihood of cancer recurrence after surgery.
An interdisciplinary team of scientists from Johns Hopkins and elsewhere has been selected to receive a $2.25 million, five-year grant from the Doris Duke Charitable Foundation to develop a practical test to predict a person's risk of colon cancer by looking for a particular biological marker in the blood.
Johns Hopkins researchers have discovered a discrete region of the monkey brain that processes pitch, the relative high and low points of sound, by recognizing a single musical note played by different instruments. Given the similarities between monkeys and man, humans may have a similar pitch-processing region in the brain too, which might one day help those with hearing and speech problems.
Cardiologists at Johns Hopkins have launched a nationwide study of more than 16,000 patients to see if a potentially life-saving procedure called angioplasty can be safely performed in smaller, community hospitals, easing access to the therapy for patients.
A team of scientists has used a non-invasive imaging technique, called SPECT/CT, to successfully trace stem cells' destinations after being injected into the body to treat animal hearts damaged by myocardial infarction, or heart attack.
An international team of researchers has discovered that human embryonic stem cell lines accumulate changes in their genetic material over time.
Earlier this summer, a 10-year-old Baltimore girl launched her own effort to help find care and a cure for others like her with uveitis, a potentially of blinding complication of juvenile rheumatoid arthritis (JRA).
The immunosuppressive drug mycophenolate mofetil, used to prevent rejection of transplanted hearts, kidneys and livers, may also be effective in controlling inflammatory eye diseases, according to a study by researchers at Johns Hopkins' Wilmer Eye Institute.
In a national survey of more than 5,000 Americans, those who said they were treated with dignity during their last medical encounter were more likely to report higher levels of satisfaction with their care, adhere to therapy and get preventive services.
Hearing-impaired individuals with severe to profound hearing loss and poor speech understanding who possess some residual hearing in one ear may experience significant communication benefit from a cochlear implant even if it is placed in the worse-hearing ear, a Johns Hopkins study suggests.
Now that spring allergy victims are finally feeling relief from the diminishing tree and grass pollen, along comes the start of the ragweed pollen season, promising new challenges and miserable rounds of sneezing, and itchy, watery eyes for the more than 36 million Americans who have hay fever.
Working with an Amish-Mennonite family tree, Johns Hopkins Wilmer Eye Institute researchers have discovered what appears to be the first human gene mutation that causes extreme farsightedness.
Using magnetic resonance imaging technology to tag the work of millions of individual strands of heart muscle fibers, researchers have successfully mapped the smallest deformations inside the beating hearts of 441 middle-aged and elderly men and women who have either silently developed heart disease or remained healthy.
Johns Hopkins Kimmel Cancer Center scientists have found that interferon, used for 30 years to treat blood cancers, multiple sclerosis and hepatitis, selectively kills colon cancer cells when combined with another standard chemotherapy agent.
Johns Hopkins scientists have identified a protein in fruit flies whose counterpart product in humans may help cause cancer.
An infectious disease expert who has spent nearly three decades studying Rocky Mountain spotted fever warns that the first widespread outbreak of the bacterial disease in Arizona is a growing and dangerous sign of how humans can inadvertently help spread infectious organisms beyond traditional state boundaries.
Results of a Johns Hopkins study suggests that doctors who follow current clinical practice guidelines when caring for an older person with multiple conditions may yield an overly complicated health regimen for the patient, or potentially harmful drug interactions.
A new study from the Brady Urological Institute at Johns Hopkins suggests an over-supply of a simple blood sugar could be a major cause of erectile dysfunction in diabetic men.
Researchers have used a magnetic resonance imaging technique called diffusion-weighted MRI, a technique that images the movement, or diffusion, of water molecules in tissues, to successfully determine the effectiveness of high-intensity focused ultrasound for treating uterine fibroids.
Using a powerful microscope and computer software, a team of scientists has developed a faster and more objective way to examine the surfaces of fossilized teeth, a practice used to figure out the diets of our early ancestors.
Researchers at Johns Hopkins have found that in people with end-stage kidney disease (ESRD), choosing peritoneal dialysis over hemodialysis increases their risk of dying by 50 percent.
Researchers have discovered that a single protein regulates secretion levels in the fruit fly's salivary gland and its skin-like outer layer.
Researchers at Johns Hopkins and The Brady Urological Institute have identified three risk factors and developed a simple reference tool that doctors can use to determine who is at high risk of death after prostate cancer recurrence following surgery.
Results of a study show that stem cell therapy can be used effectively to treat heart attacks in pigs. In just two months, stem cells harvested from another pig's bone marrow and injected into the animal's damaged heart restored heart function and repaired damaged heart muscle by 50 percent to 75 percent.
An expert panel of stem cell scientists, primatologists, philosophers and lawyers has concluded that experiments implanting, or grafting, human stem cells into non-human primate brains could unintentionally shift the moral ground between humans and other primates.
Johns Hopkins scientists have uncovered new details of how smelly things create signals in the nose that eventually go to the brain. The findings raise issues about how the process involved has been described for many years in biology textbooks.
New research sheds light on why cervical precancers disappear in some women and not in others. Scientists say the reason many of these lesions persist is an unlikely mix of human papilloma virus (HPV) strain and a woman's individual immune system.
Infectious disease specialists who have spent more than two decades leading efforts to combat HIV and AIDS worldwide are warning that limited international relief supplies of antiretroviral therapies currently being distributed in Africa, Asia and the Caribbean will not get to those who can least afford to pay for them.
Fireworks are a Fourth of July tradition to celebrate Independence Day and so are the injuries they cause. More than 50 percent of all fireworks-related ocular injuries occur around the Fourth of July holiday, and approximately 12,000 Americans are admitted to emergency rooms every year.
Heart specialists at Johns Hopkins believe they have figured a way around a persistent barrier to successful adult stem cell therapy for millions of Americans who have survived a heart attack but remain at risk of dying from chronic heart failure.
Johns Hopkins scientists have developed a way to study the earliest steps of human blood development using human embryonic stem cells grown in a lab dish instead of the embryos themselves.
If a dividing cell's activity is a pop song, then the same process in an immune cell is an extended-play dance remix. The basics of cell division are the same in both, but there's a heck of a lot more going on in immune cells, Johns Hopkins scientists have discovered.
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