A cost analysis of the controversial new Alzheimer’s disease drug aducanumab shows that ancillary care services account for nearly 20% of total Medicare costs related to the drug, or $6,564 per patient per year.
Some of the most socioeconomically disadvantaged patients — those with Medicaid or Medicare-Medicaid dual eligibility insurance — were far less likely than those with other insurance plans to return to using outpatient services at rates approaching normal, pre-pandemic levels.
Researchers in a multi-institution study led by UCLA Health call for more research as well as customized treatments, education and support to empower women living with Parkinson’s disease to address their unmet medical needs.
The UCLA Center for SMART Health and Hearst Health, have announced a partnership to offer the Hearst Health Prize awarding data science initiatives that demonstrate a positive impact on health outcomes.
A new study led by researchers at UCLA Health finds no evidence of SARS-CoV-2 transmission through breastmilk.
Researchers led by a team from the UCLA Jonsson Comprehensive Cancer Center used prostate cancer patients’ DNA to create a model that appears to predict who will have side effects from radiation.
A new study finds that while young and healthy mice show clear differences between daytime and nighttime body temperature rhythms, in older and diseased animals the difference essentially disappeared.
A study in mice led by UCLA researchers shows that removing chemical messengers in the brain that are involved in both wakefulness and addiction may make withdrawal from opioids easier and help prevent relapse.
In a study using mice, a UCLA-led team of researchers have improved upon a method they developed in 2017 that was designed to kill HIV-infected cells. The advance could move scientists a step closer to being able to reduce the amount of virus, or even eliminate it, from infected people.
New UCLA-led research in mice suggests that adding a certain type of tomato concentrate to the diet can reduce the intestinal inflammation that is associated with HIV. Left untreated, intestinal inflammation can accelerate arterial disease, which in turn can lead to heart attack and stroke.
Research led by scientists at the Jonsson Comprehensive Cancer Center (JCCC) at UCLA provides new insights into molecular “crosstalk” in pancreas cancer cells, identifying vulnerabilities that could provide a target for therapeutic drugs already being studied in several cancers.
UCLA Jonsson Comprehensive Cancer Center researchers led the development of a melanoma model of drug resistance, enabling them to study structures and dynamics resulting in intrachromosomal and extrachromosomal changes that support resistance in cancer cells.
Researchers from UCLA Jonsson Comprehensive Cancer Center and UCLA Health will participate in dozens of presentations at the annual meeting of the American Society of Hematology (ASH), held virtually and in person in Atlanta Dec. 11-14. A few of these are highlighted here.
Researchers at UCLA Jonsson Comprehensive Cancer Center led a large international study providing what is believed to be the first evidence (albeit indirect) that a recently approved imaging technique improves risk-stratification and long-term prognostic capabilities for patients with high-risk prostate cancer whose conventional imaging showed only localized disease.
Researchers at the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA have identified rare, naturally occurring T cells that are capable of targeting a protein found in SARS-CoV-2 and a range of other coronaviruses.
A combination of vaccination and naturally acquired infection appears to boost the production of maximally potent antibodies against the COVID-19 virus, new UCLA research finds.
Among HIV-positive black and Latino men who have sex with men, the use of methamphetamine combined with intimate partner violence may increase the risk for developing chronic diseases such as cardiovascular disease and other disorders.
Like locking the door but opening windows, an immune checkpoint therapy temporarily slows glioblastoma progression but fails to establish an effective anti-tumor microenvironment and appears to increase molecular interactions inhibiting long-term immune response.
A new study led by researchers at UCLA Health has found that cognitive behavioral therapy (CBT-I) prevented major depression, decreasing the likelihood of depression by over 50% as compared to sleep education therapy in adults over the age of 60 with insomnia.
Mice fed a diet high in fat, cholesterol and calories, akin to the Western diet, had higher measures of blood lipids associated with elevated levels of inflammation, a new UCLA study finds.
An experimental technology developed ” technology being developed by researchers at the UCLA Samueli School of Engineering and the David Geffen School of Medicine at UCLA uses images of suspicious-looking lesions and quickly produces a detailed, microscopic image of the skin, bypassing several standard steps typically used for diagnosis — including skin biopsy, tissue fixation, processing, sectioning and histochemical staining.
Research by UCLA Fielding School's UCLA Center for Health Policy Research, led by Dr. Ninez Ponce, Fielding School professor of health policy and management, found that Californians have varied their COVID-19 risk reduction based on their test results
Now, in a study published in the journal Cell Reports Medicine, UCLA researchers report a critical step forward in the development of an “off-the-shelf” cancer immunotherapy using human stem cell-derived invariant natural killer T cells, rare but powerful immune cells that could potentially be produced in large quantities, stored for extended periods and safely used to treat a wide range of patients with various cancers.
A UCLA study has found that young adults who have experienced discrimination have a higher risk for both short- and long-term behavioral and mental health problems.
Two of the University of California’s nationally ranked medical centers, UCLA and UCSF, have partnered with the California Department of Health Care Services (DHCS) and Office of the California Surgeon General (CA-OSG) to lead a multi-campus initiative addressing the impact of Adverse Childhood Experiences (ACEs) and other causes of toxic stress on health.
New UCLA research finds that misinformation and politicization, awareness of past injustices involving medical research, and fears about the inequitable distribution of vaccines all contributed to hesitancy to be vaccinated among Los Angeles' People of Color.
Dr. Robert Chin, a radiation oncologist with UCLA Jonsson Comprehensive Cancer Center, will describe recent research on personalized treatment for HPV-associated oropharyngeal cancer – particularly for patients with an inherited variant KRAS gene – during a panel discussion on radiation and cancer biology at ASTRO, the annual meeting of the American Society for Radiation Oncology.
In a phase 2 single-institution study, UCLA Jonsson Comprehensive Cancer Center researchers found that dose-equivalent preoperative radiation therapy for extremity/trunk soft tissue sarcoma delivered in five days rather than over the conventional five weeks produced similar benefits and treatment side effects.
An individual patient data (IPD) meta-analysis of randomized, controlled clinical trials provides strong evidence for the addition of androgen deprivation therapy (ADT) to definitive radiotherapy (RT) for the treatment of prostate cancer, with the projection that adding ADT to the treatment of 10-15 men would prevent the development of distant metastasis in one man.
A new study led by researchers at UCLA Health has found that women over the age of 50 who had breastfed their babies performed better on cognitive tests compared to women who had never breastfed. The findings, published in Evolution, Medicine and Public Health, suggest that breastfeeding may have a positive impact on postmenopausal women’s cognitive performance and could have long-term benefits for the mother’s brain.
A program offered by UCLA Health’s intensive care units is providing meaningful and compassionate support for dying patients and their families, despite the challenges brought about by COVID-19.
Over a decade ago, UCLA physician-scientists began using a pioneering gene therapy they developed to treat children born with a rare and deadly immune system disorder. They now report that the effects of the therapy appear to be long-lasting, with 90% of patients who received the treatment eight to 11 years ago still disease-free.
A new study from UCLA finds a visit from human-controlled robot encourages a positive outlook and improves medical interactions for hospitalized children.
Health care personnel who received a two-dose regimen of Pfizer–BioNTech vaccine had an 89% lower risk for symptomatic illness than those who were unvaccinated. For those who received the two-dose regimen of the Moderna vaccine, the risk was reduced by 96%.
Cinco de los sistemas de salud sin fines de lucro más grandes del condado de Los Ángeles incluyendo hospitales, clínicas e instalaciones en toda la región, anunciaron la campaña más reciente para su coalición bettertogether.health.
A UCLA study reveals new insights into the wiring of a major brain circuit that is attacked by Parkinson’s and Huntington’s disease. The findings could hone scientists’ understanding of how diseases arise in the human brain and pinpoint new therapeutic targets.
Cesarean birth rates are on the rise, and this is especially true for high-risk pregnant women who have undergone organ transplantation. While cesarean births account for 31% of all deliveries in the United States, the rate of cesarean births for pregnant people with kidney transplants is 62.6% and 44.6% for liver transplants.
LA's five most prominent health systems remain united to save lives, pivoting resources to unveil a multi-media public service education campaign to convince those avoiding care during the pandemic to get back to their health
A UCLA study suggests that many physicians may not have the knowledge or training to properly recognize how Lyme disease appears on the skin of Black patients.
Dr. Alice Soragni of the UCLA Jonsson Comprehensive Cancer Center has received a $2.5 million grant from the National Cancer Institute to develop lab-grown mini tumors that can help identify treatments for rare types of neuroendocrine cancer.
An inexpensive anti-seizure medication markedly improves learning and memory and other cognitive functions in Alzheimer’s patients who have epileptic activity in their brains, according to a study published in the Sept. 27th issue of JAMA Neurology.
A new $13.3 million contract from the National Institutes of Health’s Rapid Acceleration of Diagnostics initiative, or RADx, will enable the UCLA SwabSeq lab to expand its capacity to process thousands of COVID-19 tests a day.
Patients with dementia who had signs and risk factors of a pulmonary embolism, or a blood clot in the lungs, were much less likely to be tested for pulmonary embolism than patients without dementia who had the same signs and risk factors.
Early results from a UCLA-led clinical trial found treating women with estrogen receptor (ER)-positive and human epidermal growth factor receptor-2 (HER2)-negative early breast cancers with a novel type of anti-hormonal therapy, called an oral selective estrogen receptor degrader (SERD), led to clinically meaningful reductions in tumor activity prior to surgery.
A study led by researchers at the UCLA Jonsson Comprehensive Cancer Center has found that treating women with HER2 positive metastatic breast cancer with the HER2-targeting antibody-drug conjugate trastuzumab deruxtecan (T-DXd) significantly prolongs the length of time the disease is controlled and cancer growth is halted when compared to the current standard of care, trastuzumab emtansine (T-DM1).
A paper detailing the method that led to the US Food and Drug Administration approval for PSMA PET imaging, which was led by UCLA and UCSF and their nuclear medicine teams, was recently published in JAMA Oncology.
Physicians prescribed opioids more often to their white patients who complained of new-onset low back pain than to their Black, Asian and Hispanic patients during the early days of the national opioid crisis, when prescriptions for these powerful painkillers were surging but their dangers were not fully apparent.
Some medical procedures can put health care workers at higher risk for contracting COVID-19 and other respiratory diseases. With these high-risk procedures, it’s important that health care providers have access to personal protective equipment (PPE), including N95 masks. However, not all procedures that may seem high risk have that designation.
RSS
Medicine keyboard_arrow_right
Sciencekeyboard_arrow_right
Life keyboard_arrow_right
Business keyboard_arrow_right
Journal News keyboard_arrow_right
By Location keyboard_arrow_right
Meetings, Grants, and Events keyboard_arrow_right
