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Marking its 30th anniversary and her enduring interest and support, philanthropist Darlene Shiley has given a $10 million gift for the clinical space expansion of the Shiley Eye Institute at UC San Diego Health.

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Computer simulations from UC San Diego School of Medicine reveal the action mechanism and substrate specificity of an important blood enzyme. These findings open the door for new therapeutics against cardiovascular disease, and further support a unifying theory of phospholipase function.

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Researchers at UC San Diego School of Medicine pinpoint the regions of the brain and neural mechanisms responsible for normal or impaired development of a child’s response to baby talk and why infants with autism do not typically respond well.

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Researchers at Skaggs School of Pharmacy and Pharmaceutical Sciences at University of California San Diego discover that Botox injections may reduce anxiety.

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A celebratory groundbreaking event marks the beginning of a comprehensive revitalization project of UC San Diego’s Hillcrest campus, which upon completion will feature state-of-the-art facilities, expanded patient care services and technologies and other community amenities to promote wellbeing.

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A grant awarded to UC San Diego will allow researchers to continue working with law enforcement and health professionals to develop educational programs and interventions that reduce traffic-related injuries and deaths.

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Nixon Foundation funds effort to study and treat macular dystrophy at Shiley Eye Institute. Currently, there are no effective treatments to slow or prevent genetic condition.

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How two of UC San Diego Health’s record-breaking 81 heart transplant recipients in 2021 forged a unique bond of mutual support.

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Pediatric ophthalmologist with Shiley Eye Institute at UC San Diego Health explains why infantile cataracts are more common — and problematic — than most people realize.

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UC San Diego researchers identify new strategy to improve efficacy of immunotherapy on resistant liver cancers.

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UC San Diego School of Medicine partners with The Michael J. Fox Foundation on a clinical study to identify biomarkers of Parkinson’s disease. The study seeks to recruit 4,000 participants by the end of 2023.

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Researchers report that an abbreviated, seven-item scale can help determine with high validity a person’s level of wisdom, a potentially modifiable personality trait that has been shown to have a strong association to well-being.

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Novel randomized controlled trial found that families with high consumption of avocados experienced reduced caloric intake and an overall healthier diet, without actually changing their diet.

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The California Institute for Regenerative Medicine (CIRM) approved a $4.1 million grant to enable University of California San Diego School of Medicine researchers to advance a new chimeric antigen receptor (CAR) T-cell therapy from the laboratory into the clinic.

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Artificial intelligence-based technique reveals previously unknown cell components that may provide new clues to human development and disease.

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UC San Diego researchers have produced a single-cell chromatin atlas for the human genome. Delineating chromatin regions in cells of different human tissue types would be a major step toward understanding the role of gene regulatory elements (non-coding DNA) in human health or disease.

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A novel study — led by University of California San Diego and UCLA, in collaboration with the La Jolla Institute for Immunology — is assessing whether medicinal mushrooms and Chinese herbs provide therapeutic benefit in treating acute COVID-19 infection.

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Researchers reveal a previously unrealized complexity in cancer development, one that raises concerns and caution about targeting an enzyme popular in oncological treatments.

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Neuroimaging study reveals potential brain mechanism underlying chronic neuropathic pain in individuals with HIV. Findings may guide new clinical treatments targeting patients’ expectations for pain relief.

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A new $9 million grant from Aligning Science Across Parkinson’s (ASAP) will enable advancement of UC San Diego’s discovery that inhibiting a single gene in mice converts other cell types directly into new neurons, alleviating all Parkinson’s symptoms.

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University of California San Diego researchers, with international colleagues, describe how energy expenditure and heat production are regulated in obesity through a previously unknown cellular pathway.

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Researchers at University of California San Diego School of Medicine tested the same treatment for kids with Kawasaki disease and rare COVID-19 reaction.

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University of California San Diego researchers describe how a pair of fundamental genetic and cellular processes — aneuploidy and unfolded protein response — are exploited by cancer cells to promote tumor survival and growth.

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Philanthropists Richard and Carol Dean Hertzberg have committed $2.1 million to develop and maintain the Dean-Hertzberg Breast Cancer Database System Initiative at UC San Diego Health Moores Cancer Center to support the work of Anne Wallace, MD and her collaborators at Moores Cancer Center.

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A new trial by UC San Diego Health infectious disease specialist Maile Young Karris, MD, will use longitudinal questionnaires and qualitative interviews to assess the impact of living in an interconnected virtual village on the loneliness known to afflict older people with HIV.

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