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Research by Johns Hopkins Kimmel Cancer Center specialists has uncovered a novel pathway in the origin of pancreatic cancers, one of the deadliest of malignancies.

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Researchers at Johns Hopkins' Wilmer Eye Institute and Regeneron Pharmaceuticals have identified an experimental medicine that stops the blinding blood vessel growth associated with diabetic eye diseases and possibly macular degeneration in laboratory mice.

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Putting to rest years of controversy, an international research team led by Johns Hopkins scientists has discovered that the eye's job of detecting light is most likely carried out by just three cell types.

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For decades, scientists have proposed that learning occurs and memories are stored when connections among nerve cells are weakened or strengthened, but there's been no direct way to prove it.

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The most likely causes of brain damage among low birthweight infants are prematurity and infections, not oxygen starvation, a Johns Hopkins study has found.

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Johns Hopkins scientists have determined why a drug routinely used to treat heart arrhythmias might become a crucial addition to fighting chronic fungal infections, they report.

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As healthcare leaders from around the country continue to examine ways to improve patient safety in hospitals nationwide, a new study finds that hospitalized children experience rates of medical errors similar to those of hospitalized adults.

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Menopausal women battling hot flashes may have a new weapon to add to their arsenal: paroxetine.

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The following news tips are based on abstracts or posters to be presented at the annual meeting of the American Transplant Congress, May 30-June 4 in Washington.

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Investigators at Johns Hopkins have strong evidence that distracting patients during and after bronchoscopy with a colorful mural of a meadow and the gurgle of a babbling brook significantly enhances efforts to reduce pain.

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An airplane pilot's experience is a better indication of crash risk than his or her age, Johns Hopkins researchers say.

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While competition among managed care organizations is thought to improve access to medical care, the "administrative burden" of juggling their policies and procedures may limit patient access to high-quality mental health services, according to a national survey of more than 7,000 primary care physicians.

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Patients with severe emphysema who undergo lung volume reduction surgery (LVRS) along with medical management are more likely to function better and face no increased risk of death after two years compared to those treated with medical management alone, according to results of a five-year study at Johns Hopkins and 16 other clinical research centers across the country.

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Researchers from the Johns Hopkins Children's Center and five other institutions have found that a drug recently approved for adults with chronic hepatitis C also may be a safe and effective treatment for children with the disease.

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Scientists at the Johns Hopkins Kimmel Cancer Center have identified three genes, long linked to a rare inherited disease known as Fanconi's Anemia, that now appear to play a role in many cases of pancreatic cancer.

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Too much fun in the sun can be fatal. The medical community wants to remind summer enthusiasts that sun exposure is linked to melanoma, a deadly form of skin cancer that kills an estimated 8,000 people a year in the United States.

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A new study from Johns Hopkins researchers shows the multiple anti-HIV drug regimen called highly active antiretroviral therapy saves eyesight as well as lives.

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A team of radiologists and orthopedic specialists at Johns Hopkins Medicine has successfully used heat generated by electrode-tipped probes to destroy painful, benign bone tumors in eight of nine patients in a clinical study.

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Researchers at the Johns Hopkins Children's Center and 34 other ophthalmology centers across North America report that in children with moderate amblyopia, or "lazy eye," patching the unaffected eye for two hours daily works just as well as patching the eye for six hours, the standard amblyopia treatment.

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The Johns Hopkins University School of Medicine has been awarded a four-year, $24 million gift from the Las Vegas-based Donald W. Reynolds Foundation to establish a multidisciplinary center focused exclusively on reducing the rate of sudden cardiac death.

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Investigators from the Johns Hopkins Kimmel Cancer Center and Howard Hughes Medical Institute have completed what is believed to be the first systematic analysis of a disease-related gene family.

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Researchers at Johns Hopkins and Loma Linda universities have published what is believed to be the first peer-reviewed set of standards for planning and evaluating disaster drills anywhere in the world.

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More than two thirds of patients who undergo coronary artery bypass surgery may experience problems with their ability to think, remember and learn, and are slower at tasks like writing and drawing immediately following surgery than they were before surgery.

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Premature infants with hyperglycemia, or high blood sugar, may be at an increased risk in the first month of life for retinal detachment and blindness, say researchers from the Johns Hopkins Children's Center.

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A common version of a gene has been identified as a potent risk factor for early-onset atherosclerosis, report the Johns Hopkins scientists who first linked it to shorter life expectancy in humans.

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In what is believed to be a first-of-its-kind study, Johns Hopkins researchers have used magnetic resonance imaging to measure sodium concentrations in the cells of malignant brain tumors.

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It will take more than wider access to drugs to win the fight against AIDS in countries where medical and economic resources are limited. What is needed is a combination of affordable anti-HIV drugs and an infrastructure focused on prevention and access to effective clinical care for patients infected with the virus.

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Johns Hopkins researchers have developed an inexpensive, reliable way to make large quantities of targeted immune cells that one day may provide a life-saving defense against cancers and viral infections.

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The combination of weight loss, exercise, reduced salt intake and a healthy diet can dramatically lower blood pressure, according to a national study, called PREMIER, conducted at Johns Hopkins and three other institutions.

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1) Genetics research builds on legacy of double helix; 2) Oxygen-responsive protein gives insight to heart attack, cancer; 3) New target found for attacking marfan syndrome; 4) Severe form of bipolar disorder eases search for disease genes.

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A team of researchers from Johns Hopkins and the University of Colorado has discovered a chink in the structure of a gene-controlling protein critical in regulating the growth and death of immune, brain and muscle cells.

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The Johns Hopkins University School of Medicine will award doctor of medicine degrees to 118 women and men from 29 states and six foreign countries who will be awarded doctor of medicine degrees at The Johns Hopkins University School of Medicine"šs commencement exercises May 22, 2003.

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Researchers at the Johns Hopkins Kimmel Cancer Center have found that a single genetic mistake causes about two-thirds of papillary thyroid cancers.

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The 5 million or so heart failure patients in this country traditionally have been treated with nitroglycerin or other drugs that release nitric oxide into the bloodstream. While these medicines increase the heart's ability to contract, they also blunt chemical signals allowing the heart to fully relax and pump most effectively.

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Experts from Johns Hopkins and the Centers for Disease Control and Prevention and public health officials from Toronto and Singapore will discuss the latest developments on the recent outbreak of SARS (severe acute respiratory syndrome).

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Genetic testing to detect carriers of cystic fibrosis is being routinely offered to many couples seeking prenatal care. Recent reports in the medical literature indicate that guidelines for safe and appropriate testing are not always being followed.

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A recent shoulder injury to All-Star baseball player Derek Jeter is very common in some sports but less ordinary in baseball. For this reason, no one knows for certain whether Jeter will need surgery and/or months of rehabilitation after suffering what doctors describe as shoulder instability.

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Studies have suggested that the "metabolic syndrome" -- a cluster of health problems that includes high blood pressure, cholesterol and blood sugar, and obesity -- increases the risk of heart disease.

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Pairing transesophageal magnetic resonance imaging with standard cardiac MRI offers physicians great views of plaque buildup in the aorta, the heart's main artery.

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After years of frustrating searches for genes that contribute to mental illness, researchers at Johns Hopkins studying families with a severe form of manic depressive illness, called psychotic bipolar disorder, may be one step closer to finding the genetic underpinnings of both bipolar disorder and schizophrenia.

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You literally are what you eat, at least when it comes to the amount of abdominal visceral fat, Johns Hopkins researchers say.

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A Johns Hopkins-led research team has successfully used a technique to rapidly find fruit fly genes involved in a cell signaling pathway called Hedgehog, which is critical to proper embryo development and a key trigger in some cancers, including the deadly childhood brain cancer medulloblastoma.

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Listed below are story ideas from The Johns Hopkins University School of Medicine's Division of Sports Medicine.

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Researchers from the Johns Hopkins Children's Center report that a group of rare urological defects, including bladder development outside the body, may be more common in children conceived through in vitro fertilization (IVF). The researchers caution, however, that the findings are preliminary, and should not necessarily dissuade couples from considering the procedure.

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Johns Hopkins scientists have discovered that primitive human embryonic stem (ES) cells, temperamental in the lab, can be grown with the help of special cells from bone marrow, offering an easily obtained and well-studied source of human cells to nurture the human ES cells as they divide.

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Johns Hopkins scientists have found a way to predict with a simple blood test which people may be at higher than normal risk for the most common form of colon cancer.

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Johns Hopkins researchers last year reported that an experimental treatment for severe ragweed allergy consisting of just six shots in six weeks dramatically reduced allergic symptoms such as runny nose, nasal congestion and sneezing, and nearly eliminated the need for relief medications like antihistamines and decongestants.

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Researchers at the Johns Hopkins Children's Center and the Johns Hopkins Bloomberg School of Public Health report that male rats whose mothers were fed diets containing genistein, a chemical found in soybeans, developed abnormal reproductive organs and experienced sexual dysfunction as adults.

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Studying mice, scientists from Johns Hopkins have successfully prevented a molecular event in brain cells that they've found is required for storing spatial memories.

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By studying mice, Johns Hopkins scientists have discovered that excessive activity of an important signaling protein, TGF-beta, likely underlies a variety of problems in Marfan syndrome, including the tendency to develop emphysema.