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Released: 4-Dec-2001 12:00 AM EST
A Psychiatric View of Terrorism
Johns Hopkins Medicine

In the wake of Sept. 11, psychiatry's contribution to America's response is to defend not against bombs, but against confusion. What is needed now more than ever is a realistic view of what terrorists do, how they think and how to stop them, according to the University Distinguished Service Professor of Psychiatry at The Johns Hopkins University School of Medicine and formerly psychiatrist in chief at The Johns Hopkins Hospital.

27-Nov-2001 12:00 AM EST
New Bacteria Target Cancers in Mice
Johns Hopkins Medicine

Scientists from the Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins have created bacteria that selectively target large advanced tumors in mice.

21-Nov-2001 12:00 AM EST
Potential New Screening Test for Prostate Cancer
Johns Hopkins Medicine

Scientists at Johns Hopkins have found that measuring the level of a chemical process linked to a genetic change associated with prostate cancer could greatly strengthen standard detection of early-stage curable disease.

Released: 16-Nov-2001 12:00 AM EST
Sidney Kimmel Gives $150M For Cancer Research and Patient Care
Johns Hopkins Medicine

The Johns Hopkins University announced that Sidney Kimmel, founder and chairman of Jones Apparel Group, has donated $150M for cancer research and patient care - the largest single gift ever to the University. With more than a third of the gift already received, the Hopkins Cancer Center officially will be called The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins.

Released: 15-Nov-2001 12:00 AM EST
New Analysis Promises To Speed Application of Human Genome Draft
Johns Hopkins Medicine

A small team of scientists has dramatically improved "gene chip" technology, for the first time making it a practical method for rapidly determining the sequence of genetic building blocks. The advance is likely to speed the search for disease-related genetic changes.

15-Nov-2001 12:00 AM EST
Mice With Human Protein Exhibit Age-Related Memory Loss
Johns Hopkins Medicine

A new player is emerging in the complex world of the brain. This player, a protein called COX-2, appears to be critically important in the brain's normal functioning, as evidenced by its ability to wreak havoc in mice that have too much of it.

15-Nov-2001 12:00 AM EST
Effects of Arsenic on Human Cells
Johns Hopkins Medicine

Researchers at Johns Hopkins report discovering a mechanism that may account for the paradoxical effects of arsenic, which is both a treatment for cancer and a carcinogen.

14-Nov-2001 12:00 AM EST
Herpes Virus Infection Associated With Schzophrenia In Offspring
Johns Hopkins Medicine

Scientists at Johns Hopkins Children's Center and six other research centers have found that mothers who have had a herpes simplex virus type 2 (HSV-2) infection at the time of birth are more likely to give birth to children who develop schizophrenia or other psychotic disorders. HSV-2 is a sexually transmitted disease that differs from its common, cold sore-causing cousin, HSV-1.

14-Nov-2001 12:00 AM EST
Depressed Heart Attack Survivors Unlikely To Change Behavior
Johns Hopkins Medicine

Some depressed heart attack survivors are so convinced they'll never be healthy again that their belief becomes a self-fulfilling prophecy. A Johns Hopkins study demonstrates that defeatist attitudes lead to unwillingness to alter unhealthy habits and that this, more than physical status, puts them at risk for early death. Results will be presented at the American Heart Association's annual Scientific Sessions.

14-Nov-2001 12:00 AM EST
Nitroglycerin Not Foolproof in Diagnosing Heart Disease
Johns Hopkins Medicine

For years, hospital emergency physicians have used nitrogylcerin as a gold standard for identifying heart disease as a cause of chest pain. If a patient presents with chest pain, and a nitroglycerin pill or spray under the tongue relieves the pain within a few minutes, the likely diagnosis is coronary artery disease.

Released: 13-Nov-2001 12:00 AM EST
Study Helps Identify Key Step In Simple Motor Learning
Johns Hopkins Medicine

A Neuroscientist is excited about his latest research findings, even though the experiments' results echo his four-year-old son's tendency to answer questions with a resounding "No, no, no."

13-Nov-2001 12:00 AM EST
Gout Drug Could Offer Hope for Heart Failure Patients
Johns Hopkins Medicine

A medication commonly used for gout holds possibilities for the treatment of heart failure, Johns Hopkins researchers report. It's a drug that works by a new principle, namely, directly decreasing heart muscle's need for energy and making it contract more efficiently.

13-Nov-2001 12:00 AM EST
Positive Attitude Is Best Prevention Against Heart Disease
Johns Hopkins Medicine

A positive outlook may offer the strongest known protection against heart disease in adults at risk, according to a Johns Hopkins study. The report, which looked at nearly 600 adults with a family history of heart disease, will be presented Nov. 12 at the American Heart Association's annual Scientific Sessions in Anaheim, Calif.

Released: 7-Nov-2001 12:00 AM EST
T Cell Molecules May Play a Role In Ischemia
Johns Hopkins Medicine

Ischemia, or an interruption in blood flow to tissue, greatly decreases the success of transplanted kidneys. There's no specific treatment, partly because physicians don't know exactly how the injury occurs. But now, a new study shows that in mice, at least, tiny molecules within specialized immune system cells may hold some clues.

7-Nov-2001 12:00 AM EST
Blood Drug May Decrease Painful Crises In Children With Sickle Cell Disease
Johns Hopkins Medicine

Researchers at Johns Hopkins Children's Center and 20 other hospitals report that a novel drug appears to make blood cells slip around each other and more easily through blood vessels, shortening the duration of painful crises experienced by children with sickle cell disease. The drug had a similar but less potent effect in adults.

Released: 30-Oct-2001 12:00 AM EST
Movement of Single Molecules Imaged in Live Organism
Johns Hopkins Medicine

Understanding attraction is difficult enough, but it's a little less so these days, at least in amoeba living in the lab of a Johns Hopkins scientist.

Released: 26-Oct-2001 12:00 AM EDT
Two Hopkins Faculty Members Receive Genius Awards
Johns Hopkins Medicine

The John D. and Catherine T. MacArthur Foundation has awarded two Johns Hopkins faculty members MacArthur Fellowships. The so-called "genius awards" go to Kay Redfield Jamison, Ph.D., professor of psychiatry, and Geraldine Seydoux, Ph.D., associate professor of molecular biology and genetics, both in the School of Medicine.

Released: 23-Oct-2001 12:00 AM EDT
Two Separate Controls Regulate Chromosome Copying in Yeast
Johns Hopkins Medicine

The crucial job of ensuring that just one copy of a genome gets made during cell division turns out to be shared by two independent "controllers," researchers from Johns Hopkins School of Medicine report.

Released: 19-Oct-2001 12:00 AM EDT
Prevalence of ICU Nurses Has Strong Link to Patient Outcomes
Johns Hopkins Medicine

Patients undergoing high-risk surgeries are more likely to have post-operative complications, including difficulty breathing, if their hospital's intensive care unit (ICU) isn't sufficiently staffed by nurses, according to a Johns Hopkins study of Maryland hospitals.

Released: 17-Oct-2001 12:00 AM EDT
Say What? Neurons and Fat Cells Have A Dialogue in the Lab
Johns Hopkins Medicine

Growing fat cells and nerve cells in the same dish has produced what is believed to be the first demonstration of two-way communication between the cell types, say Johns Hopkins scientists.

17-Oct-2001 12:00 AM EDT
Morphine-Like Drugs Could Offer Relief for Amputees
Johns Hopkins Medicine

Fifty to 80 percent of all amputees experience pain in their stumps or what feels like the missing limbs long after surgical wounds have healed. Now new research from Johns Hopkins suggests the two pains have different sources, bringing us a step closer in understanding what types of drugs might help.

Released: 13-Oct-2001 12:00 AM EDT
Missing Link Between Major Proteins in Parkinson's Disease
Johns Hopkins Medicine

A new study identifies an important link between the two main inherited forms of Parkinson's disease, and might also connect them to non-inherited versions, Hopkins scientists report.

5-Oct-2001 12:00 AM EDT
Size Matters: Shortest Telomeres Initiate Cellular Havoc
Johns Hopkins Medicine

Using genetically engineered mice, scientists from The Johns Hopkins University School of Medicine have found that events associated with losing the function of telomeres, the repetitive ends of chromosomes, depend on the length of the shortest telomere in a cell, not the commonly measured average length.

2-Oct-2001 12:00 AM EDT
Drug Therapy Leads to Long-Term Remissions in Aplastic Anemia Patients
Johns Hopkins Medicine

Researchers at Johns Hopkins, Hahnemann University, and University of Maryland report sustained, treatment-free remissions in studies of a novel drug therapy approach to treating a deadly blood disorder known as aplastic anemia.

2-Oct-2001 12:00 AM EDT
Ketogenic Diet Reduces Seizures In Many Children
Johns Hopkins Medicine

Johns Hopkins neurologists report that a rigorously high-fat, low-carbohydrate diet not only reduces the number of seizures in children with severe seizure disorders, but also keeps the frequency of attacks lower years after the diet is stopped.

Released: 28-Sep-2001 12:00 AM EDT
Johns Hopkins University Offers Mini-Med School
Johns Hopkins Medicine

Get through medical school in 12 hours for less than $150? Not quite, but a new program featuring leading physicians and researchers from Johns Hopkins Medicine and The Johns Hopkins University Bloomberg School of Public Health comes pretty close. Participants get eight 1.5-hour sessions with leading medical experts discussing everything from cancer to genetics to mysteries of the mind to human health and environmental change.

Released: 26-Sep-2001 12:00 AM EDT
Novel Means for Stopping Transcription Found
Johns Hopkins Medicine

Researchers have discovered what is believed to be a novel method in yeast for governing gene expression at the end, rather than the beginning, of transcription, the process of reading DNA to make RNA.

21-Sep-2001 12:00 AM EDT
Scientist Evaluates Latest Findings on the Ancestry of Whales
Johns Hopkins Medicine

From Moby Dick to Shamu, whales have long fascinated humans. Their remarkable status as ocean-dwelling mammals, along with dolphins and porpoises, at once makes them related to us and yet inconceivably different from us. Thus their evolution -- the developmental steps required to leave solid ground for a life in the water -- has long fascinated scientists.

15-Sep-2001 12:00 AM EDT
Blood Pressure Measures During Exercise Can Indicate Unhealthy Hearts
Johns Hopkins Medicine

A blood pressure reading taken during exercise is a more accurate test for early heart disease than one taken at rest, according to a study presented Sept. 14 at the annual meeting of the American Association of Cardiovascular and Pulmonary Rehabilitation in Minneapolis.

Released: 11-Sep-2001 12:00 AM EDT
Gene Therapy May Be a Tool to Prevent Blindness
Johns Hopkins Medicine

Gene therapy may one day be used to halt or even prevent the overgrowth of blood vessels in the eye that blinds patients with macular degeneration and diabetic retinopathy, according to two recent studies led by researchers at Johns Hopkins' Wilmer Eye Institute.

11-Sep-2001 12:00 AM EDT
Alternative Therapy Use by Parkinson's Patients
Johns Hopkins Medicine

In a study of more than 200 patients with Parkinson's disease, 40 percent used at least one type of alternative therapy, such as vitamins/herbs, massage and acupuncture. Over half of the patients failed to inform their physicians about the use of alternative therapies.

Released: 6-Sep-2001 12:00 AM EDT
Experimental Drug Decreases Age-Related Blood Vessel Stiffening
Johns Hopkins Medicine

An experimental drug may reverse stiffening of the cardiovascular system that occurs with aging, according to a national study led by Johns Hopkins physicians.

Released: 5-Sep-2001 12:00 AM EDT
All-New September Edition of @Hopkins Medicine Now Online
Johns Hopkins Medicine

The Class of 2005 Arrives...Saving Voice: New Approach to Larynx Cancer...Mike Weisfeldt: New Chairman of the Department of Medicine. These stories and more now are posted on the Web in the all-new September edition of Hopkins' online magazine, @Hopkins Medicine.

Released: 5-Sep-2001 12:00 AM EDT
Peripheral Artery Disease Is Underdiagnosed and Undertreated
Johns Hopkins Medicine

Only half of people with peripheral artery disease (PAD), a condition where blood vessels in the arms and legs can become clogged with cholesterol, are appropriately diagnosed and treated, a Johns Hopkins expert says.

Released: 25-Aug-2001 12:00 AM EDT
Reforming Psychiatry's DSM
Johns Hopkins Medicine

Modern psychiatry has become mired in a system of disease classification that defines mental disorders by the way they look and not on biological or psychological processes, according to Paul R. McHugh, M.D., Henry Phipps Professor and chair of the Department of Psychiatry and Behavioral Sciences at the Johns Hopkins University.

Released: 16-Aug-2001 12:00 AM EDT
Church-based Programs Lower Heart Disease Risk For African-American Women
Johns Hopkins Medicine

Church-based nutrition and exercise programs can move African-American women to adopt healthier habits, according to a study led by Johns Hopkins researchers.

Released: 15-Aug-2001 12:00 AM EDT
Food Allergy Reactions in Schools: Improvements Needed
Johns Hopkins Medicine

Parents, add this to your back-to-school to-do list: meet with teachers to discuss food allergies. According to a recent Hopkins study, published in the Archives of Pediatrics and Adolescent Medicine, roughly one in five food-allergic children will have an allergic reaction while in school, and teachers may not know how to handle an attack properly.

15-Aug-2001 12:00 AM EDT
Genetic Mutation May Be Key to Onset of Deadly Skin Cancer
Johns Hopkins Medicine

A Johns Hopkins scientist and a team of collaborators have discovered how precancerous moles may progress to melanomas, the most deadly type of skin cancer. The report describes a link between two genes that trigger skin cancers and could serve as early diagnostic markers for the disease.

Released: 31-Jul-2001 12:00 AM EDT
Guide to AIDS Care Marks Historic Milestone in Battle Against AIDS
Johns Hopkins Medicine

The 10th edition of the Hopkins guide to AIDS care, Medical Management of HIV Infection mirrors a decade's history of medical successes and challenges. The internationally renowned publication began in 1991 as a 28-page booklet with 10 pages devoted to anti-HIV therapy as well as treatment of opportunistic infections and complications. It is now a 356-page book.

Released: 28-Jul-2001 12:00 AM EDT
Gene-Targeted Therapy Promises Improved Cure Rates for Leukemia
Johns Hopkins Medicine

Researchers at the Johns Hopkins Oncology Center have developed a new gene-based therapy that they hope will transform one of the most lethal types of adult leukemia to one of the most treatable.

Released: 25-Jul-2001 12:00 AM EDT
New Way to Block HIV Transmission
Johns Hopkins Medicine

Cholesterol is instrumental in HIV's ability to infiltrate cells, and removing this fatty material from a cell's membrane blocks infection, according to a Johns Hopkins study.

19-Jul-2001 12:00 AM EDT
Researchers Unravel Mysteries of Water Regulation in Humans
Johns Hopkins Medicine

Acting on a scientific hunch, Hopkins medical sleuths set out to find individuals with an extremely rare disorder affecting their ability to internally process water. Using international blood banks, the investigators identified two such persons, confirming their belief that the absence of a certain protein interferes with the body's ability to regulate its water levels.

Released: 17-Jul-2001 12:00 AM EDT
Mighty Mice Research Brings Muscle Growth Closer to Reality
Johns Hopkins Medicine

The Johns Hopkins scientists who first created "mighty mice" by genetically engineering animals with a missing growth regulator called myostatin have now created a second group of mice whose genetic makeup shows it's possible to get the same effect by blocking the gene for myostatin, rather than entirely knocking it out.

11-Jul-2001 12:00 AM EDT
Therapy Hinders AIDS Virus from Evolving Drug Resistance
Johns Hopkins Medicine

A team of scientists from Johns Hopkins Children's Center and two other institutions have found that low levels of HIV-1 virus in the blood of children and adults undergoing a common combination drug therapy does not necessarily indicate the virus is becoming resistant to these life-prolonging medications.

9-Jul-2001 12:00 AM EDT
Asthmatic Blacks Get Less High-Quality Asthma Care
Johns Hopkins Medicine

The care of asthmatic African Americans falls short of many recommendations contained in national guidelines, compared to whites, according to a new study by Johns Hopkins researchers.

Released: 29-Jun-2001 12:00 AM EDT
News Tips from Johns Hopkins Medical Institutions
Johns Hopkins Medicine

1) Faulty bee tests make for stinging surprises; 2) Mexican-Americans at high risk for diabetic retinopathy; 3) Novel measure of blood cholesterol better predicts death from heart disease; 4) Women facing cancer treatment may still have fertility options.

Released: 21-Jun-2001 12:00 AM EDT
Joint Research Program, Training Center
Johns Hopkins Medicine

Researchers from Johns Hopkins and Toshiba Corporation Medical Systems Company have formed a joint research program at Hopkins to develop new, minimally invasive procedures using combinations of CT scans and fluoroscopy.

19-Jun-2001 12:00 AM EDT
Hopkins Participates in First Major Digital Mammography Study
Johns Hopkins Medicine

The Johns Hopkins Medicine Department of Radiology has been selected to take part in the first major study assessing the value of digital mammography versus standard mammography. The study, called the American College of Radiology Imaging Network (ACRIN) study, is funded with a $25 million grant from the National Cancer Institute.

15-Jun-2001 12:00 AM EDT
Researchers Combat Sickle Cell Anemia in Mice with Mini-Transplant
Johns Hopkins Medicine

Researchers at Johns Hopkins Children's Center report success in treating sickle cell disease in mice with a modified bone marrow transplant. The finding adds further support to human trials now under way at the Children's Center.

9-Jun-2001 12:00 AM EDT
Drug Bottles May Place Latex Allergic Patients at Risk
Johns Hopkins Medicine

Armed with evidence from a recent study of latex allergy skin reactions in patients' scientists at Johns Hopkins encourage the Food and Drug Administration and drug makers to label all current vials as "containing natural rubber" where appropriate and convert to using synthetic rubber for all medicine bottle stoppers.



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