Newswise — Scientists at the University of Southampton have shown that higher muscle mass is strongly linked with healthier bone development in children.

Researchers also found no relationship between fat mass and bone development, indicating it is not an important factor in childhood skeletal strength.

A new study, published in the journal Bone, by researchers from the University’s Medical Research Council Lifecourse Epidemiology Unit shows a link between the amount of lean muscle and healthy bone development, indicated by the size, shape and density of limb bones, in children at ages six and seven.

Detailed measurements of 200 children enrolled in the Southampton Women’s Survey were taken soon after birth and then again at ages six to seven years old. State of the art scanning equipment was used to assess bone mineral density, shape and size of the tibia (the shin bone), and body composition.

“Bone strength and size is important because they are significant factors in long term osteoporosis and fracture risk,” says Dr Rebecca Moon, lead investigator of the study. “A ten per cent increase in peak bone mass will delay the onset of osteoporosis by 13 years. These findings point to the importance of early childhood physical activity to optimise muscle and bone growth.”

The team also found that the relationship between changes in lean muscle and bone development was stronger in girls than in boys, despite the ages of the children ruling out the onset of puberty as a factor.

Professor Cyrus Cooper, Director of the MRC Lifecourse Epidemiology Unit, said: "This is a wonderful example of a biomedical discovery made by combining state of the art imaging methodologies with the world leading population science, for which Southampton has an established international reputation."


Notes for editors1. For a copy of the paper Longitudinal changes in lean mass predict pQCT measures of tibial geometry and mineralisation at 6-7 years please contact Steven Williams, Media Relations, University of Southampton, Tel: 023 8059 2128, email: [email protected] 2. For interview opportunities with Dr Rebecca Moon please contact media relations.3. Through world-leading research and enterprise activities, the University of Southampton connects with businesses to create real-world solutions to global issues. Through its educational offering, it works with partners around the world to offer relevant, flexible education, which trains students for jobs not even thought of. This connectivity is what sets Southampton apart from the rest; we make connections and change the world. further information contact:Steven Williams, Media Relations, University of Southampton, Tel: 023 8059 2128, email: [email protected]

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