Fred Hutchinson Cancer Research Center

Tip Sheet: HIV and COVID-19, antibody interactions, immune responses to colorectal cancer and how Fred Hutch is getting back to work

SEATTLE – June 2, 2020 – Below are summaries of recent Fred Hutch research findings and other news with links for additional background and media contacts.

__________________________________________________________________________

COVID-19

Vaccinating the world: Two global experts explain what it will take to succeed
Dr. Larry Corey and Dr. John Mascola join Fred Hutch President and Director Dr. Tom Lynch to discuss the challenges and opportunities in accelerating development and distribution of COVID-19 vaccines for our integrated world in this webinar on Friday, June 5, 2020 at 11 am PST/ 2 pm EST.

What happens when cancer patients get COVID-19?
A large new study of cancer patients with COVID-19 clearly shows patients with active cancer — or who suffer from additional comorbidities such as diabetes or heart disease — have worse outcomes.

When COVID-19 crosses paths with HIV
Researchers at Fred Hutch are trying to assess whether HIV puts people at higher risk COVID-19 through a new epidemiological study of over 35,000 people living with HIV across the US. The study aims to identify risk factors for those with HIV who also had COVID-19 and understand if they are at risk of more severe infection.  

How Fred Hutch is using science to get back to doing science
Fred Hutch is tapping its decades of scientific expertise to move forward in finding ways to safely dial back up its employees on campus while supporting others working remotely. See steps being taken, plus a video of Fred Hutch’s facilities director on how his team is managing during the pandemic.

______________________________________________________________________

HIV

Injectable HIV drug prevents infections
In a “real win for HIV prevention,” an international trial of an injectable drug designed to prevent HIV showed those who received it had fewer new HIV infections than those who received the once-a-day HIV prevention pill Truvada.

_____________________________________________________________________

Healthcare economics

NIH grant to fund new financial-toxicity intervention
A new collaboration between Fred Hutch and the SWOG Cancer Research Network will road-test a program designed to curb financial toxicity related to cancer treatment. The intervention will give cancer patients access to proactive financial counseling and financial navigators as part of their treatment plan.

______________________________________________________________________

Precision medicine

Immune response in colorectal cancer: What helps, what hurts?
A new $3.66 million grant from the National Cancer Institute will help Fred Hutch researchers, part of the Genetics and Epidemiology of Colorectal Cancer Consortium, better understand the body’s natural immune response to colorectal cancer and what, exactly, drives it.

$3.5M grant to develop safer treatment for inherited blood disorders
Drs. Hans-Peter Kiem and Roland Walter will explore ways to precisely deliver powerful radioactive particles to blood and marrow cells while sparing other nonblood cells and tissues.

______________________________________________________________________

Pediatric Oncology

Cancer’s toll on the heart decades down the road
Dr. Eric Chow and colleagues explore two key questions related to child cancer survivorship: Is there anything doctors can do during a child’s treatment to protect their heart? And for adult survivors, what can we do to monitor and reduce the risk of heart disease?

______________________________________________________________________

Basic sciences

Studying the complex interactions between antibodies and viral targets
Dr. Tal Einav was named a Damon Runyon Quantitative Biology Fellow, which supports cancer-related computation research. He will create maps that model how complex mixes of antibodies interact.

______________________________________________________________________

Other notable news

Dr. Hans-Peter Kiem elected vice president of American Society of Gene & Cell Therapy

Health equity trailblazers recognized

# # #

At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first National Cancer Institute-funded cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network.




Filters close

Showing results

110 of 2454
Released: 3-Jul-2020 10:25 AM EDT
Lack of lockdown increased COVID-19 deaths in Sweden
University of Virginia Health System

Sweden’s controversial decision not to lock down during COVID-19 produced more deaths and greater healthcare demand than seen in countries with earlier, more stringent interventions, a new analysis finds.

Released: 2-Jul-2020 3:10 PM EDT
Researchers outline adapted health communications principles for the COVID-19 pandemic
CUNY Graduate School of Public Health and Health Policy

The COVID-19 pandemic has introduced unique challenges for public health practitioners and health communicators that warrant an expansion of existing health communication principles to take into consideration.

Released: 2-Jul-2020 1:40 PM EDT
Collectivism drives efforts to reduce the spread of COVID-19
University of Kent

Research from the University of Kent has found that people who adopt a collectivist mindset are more likely to comply with social distancing and hygiene practices to help reduce the spread of COVID-19.

Released: 2-Jul-2020 12:30 PM EDT
Tiny mineral particles are better vehicles for promising gene therapy
University of Wisconsin-Madison

University of Wisconsin–Madison researchers have developed a safer and more efficient way to deliver a promising new method for treating cancer and liver disorders and for vaccination — including a COVID-19 vaccine from Moderna Therapeutics that has advanced to clinical trials with humans.

Newswise: Newer variant of COVID-19–causing virus dominates global infections
Released: 2-Jul-2020 12:10 PM EDT
Newer variant of COVID-19–causing virus dominates global infections
Los Alamos National Laboratory

Research out today in the journal Cell shows that a specific change in the SARS-CoV-2 coronavirus virus genome, previously associated with increased viral transmission and the spread of COVID-19, is more infectious in cell culture.

Newswise: From Wuhan to San Diego—How a mutation on the novel coronavirus has come to dominate the globe
Released: 2-Jul-2020 12:05 PM EDT
From Wuhan to San Diego—How a mutation on the novel coronavirus has come to dominate the globe
La Jolla Institute for Immunology

Two variants of the novel coronavirus (SARS-CoV-2), called G614 and D614, were circulating in mid-March. A new study shows that the G version of the virus has come to dominate cases around the world. They report that this mutation does not make the virus more deadly, but it does help the virus copy itself, resulting in a higher viral load, or "titer," in patients.

Released: 2-Jul-2020 11:50 AM EDT
New Study Explains Potential Causes for “Happy Hypoxia” Condition in COVID-19 Patients
Loyola Medicine

A new research study provides possible explanations for COVID-19 patients who present with extremely low, otherwise life-threatening levels of oxygen, but no signs of dyspnea (difficulty breathing). This new understanding of the condition, known as silent hypoxemia or “happy hypoxia,” could prevent unnecessary intubation and ventilation in patients during the current and expected second wave of coronavirus.

Released: 2-Jul-2020 10:15 AM EDT
Stemming the Spread of Misinformation on Social Media
Association for Psychological Science

New research reported in the journal Psychological Science finds that priming people to think about accuracy could make them more discerning in what they subsequently share on social media.

29-Jun-2020 9:00 AM EDT
Coronavirus damages the endocrine system
Endocrine Society

People with endocrine disorders may see their condition worsen as a result of COVID-19, according to a new review published in the Journal of the Endocrine Society.


Showing results

110 of 2454

close
1.146