Fred Hutchinson Cancer Research Center

Tip Sheet: HIV and COVID-19, antibody interactions, immune responses to colorectal cancer and how Fred Hutch is getting back to work

SEATTLE – June 2, 2020 – Below are summaries of recent Fred Hutch research findings and other news with links for additional background and media contacts.

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COVID-19

Vaccinating the world: Two global experts explain what it will take to succeed
Dr. Larry Corey and Dr. John Mascola join Fred Hutch President and Director Dr. Tom Lynch to discuss the challenges and opportunities in accelerating development and distribution of COVID-19 vaccines for our integrated world in this webinar on Friday, June 5, 2020 at 11 am PST/ 2 pm EST.

What happens when cancer patients get COVID-19?
A large new study of cancer patients with COVID-19 clearly shows patients with active cancer — or who suffer from additional comorbidities such as diabetes or heart disease — have worse outcomes.

When COVID-19 crosses paths with HIV
Researchers at Fred Hutch are trying to assess whether HIV puts people at higher risk COVID-19 through a new epidemiological study of over 35,000 people living with HIV across the US. The study aims to identify risk factors for those with HIV who also had COVID-19 and understand if they are at risk of more severe infection.  

How Fred Hutch is using science to get back to doing science
Fred Hutch is tapping its decades of scientific expertise to move forward in finding ways to safely dial back up its employees on campus while supporting others working remotely. See steps being taken, plus a video of Fred Hutch’s facilities director on how his team is managing during the pandemic.

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HIV

Injectable HIV drug prevents infections
In a “real win for HIV prevention,” an international trial of an injectable drug designed to prevent HIV showed those who received it had fewer new HIV infections than those who received the once-a-day HIV prevention pill Truvada.

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Healthcare economics

NIH grant to fund new financial-toxicity intervention
A new collaboration between Fred Hutch and the SWOG Cancer Research Network will road-test a program designed to curb financial toxicity related to cancer treatment. The intervention will give cancer patients access to proactive financial counseling and financial navigators as part of their treatment plan.

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Precision medicine

Immune response in colorectal cancer: What helps, what hurts?
A new $3.66 million grant from the National Cancer Institute will help Fred Hutch researchers, part of the Genetics and Epidemiology of Colorectal Cancer Consortium, better understand the body’s natural immune response to colorectal cancer and what, exactly, drives it.

$3.5M grant to develop safer treatment for inherited blood disorders
Drs. Hans-Peter Kiem and Roland Walter will explore ways to precisely deliver powerful radioactive particles to blood and marrow cells while sparing other nonblood cells and tissues.

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Pediatric Oncology

Cancer’s toll on the heart decades down the road
Dr. Eric Chow and colleagues explore two key questions related to child cancer survivorship: Is there anything doctors can do during a child’s treatment to protect their heart? And for adult survivors, what can we do to monitor and reduce the risk of heart disease?

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Basic sciences

Studying the complex interactions between antibodies and viral targets
Dr. Tal Einav was named a Damon Runyon Quantitative Biology Fellow, which supports cancer-related computation research. He will create maps that model how complex mixes of antibodies interact.

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Other notable news

Dr. Hans-Peter Kiem elected vice president of American Society of Gene & Cell Therapy

Health equity trailblazers recognized

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At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first National Cancer Institute-funded cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network.




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Newswise: Proteolytic Enzymes for Covid-19 Studied in 3D for the First Time in Thailand by Chula Biochemists
Released: 4-Dec-2020 8:45 AM EST
Proteolytic Enzymes for Covid-19 Studied in 3D for the First Time in Thailand by Chula Biochemists
Chulalongkorn University

A team of biochemists from Chulalongkorn University became the first researchers in Thailand to study proteolytic enzymes for the Covid–19 virus at a molecular level in 3D, possibly leading to the development of Covid–19 treatments.

Newswise: UC San Diego Bolsters Aggressive Return to Learn Plan to Prevent Outbreaks on Campus
Released: 4-Dec-2020 8:35 AM EST
UC San Diego Bolsters Aggressive Return to Learn Plan to Prevent Outbreaks on Campus
University of California San Diego

UC San Diego’s nationally recognized, evidence-based Return to Learn program employs a comprehensive suite of education, monitoring, testing, intervention and notification tools that no other university is using. And the program continues to expand—including a recent introduction of weekly self-administered student testing kits, growth of the campus’s wastewater viral monitoring program and widespread use of the cellphone-based CA COVID Notify exposure notification system.

Newswise: Pediatric ER Saw Steep Drop in Asthma Visits During Spring COVID-19 Lockdown
1-Dec-2020 8:00 AM EST
Pediatric ER Saw Steep Drop in Asthma Visits During Spring COVID-19 Lockdown
American Thoracic Society (ATS)

A new study published online in the Annals of the American Thoracic Society discusses a steep drop off from prior years in asthma-related emergency department (ED) visits at Boston Children’s Hospital during the spring 2020 COVID-19 surge and lockdown.

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Released: 3-Dec-2020 3:05 PM EST
Study finds COVID-19 hindering US academic productivity of faculty with young children
University of Tennessee Health Science Center

The academic productivity of higher education faculty In the United States in the science, technology, engineering, mathematics, and medicine (STEMM) fields with very young children suffered as a result of the stay-at-home orders during the early months of the coronavirus pandemic, according to a new study by researchers at the University of Tennessee Health Science Center, the University of Florida College of Medicine, and the University of Michigan School of Medicine.

Released: 3-Dec-2020 2:50 PM EST
Kidney disease leading risk factor for COVID-related hospitalization
Geisinger Health System

An analysis of Geisinger's electronic health records has revealed chronic kidney disease to be the leading risk factor for hospitalization from COVID-19.

Newswise: Identity Verification During the Age of COVID-19
Released: 3-Dec-2020 2:25 PM EST
Identity Verification During the Age of COVID-19
Homeland Security's Science And Technology Directorate

S&T's Biometric Technology Rally focused on the ability of acquisition systems and matching algorithms to recognize travelers without asking them to remove their masks, thereby reducing risk for frontline workers.

access_time Embargo lifts in 2 days
Embargo will expire: 10-Dec-2020 11:00 AM EST Released to reporters: 3-Dec-2020 2:20 PM EST

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