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The Wistar Institute Awarded More Than $1.4 Million to Create a Malaria Vaccine Through Synthetic DNA-Based Technology

Wistar is pleased to announce it has been awarded a $1,494,972 grant by the Bill & Melinda Gates Foundation to advance a DNA-based vaccine candidate for protection against malarial infection utilizing a synthetic DNA platform created in the lab of...
18-Jan-2018 11:05 AM EST Add to Favorites

When it Comes to Science, it’s a Small, Small World

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Immortalized human skin cells that look like a psychedelic otherworldly galaxy and a living algae colony releasing its daughter colonies that could be mistaken for Pacman gobbling up ghosts are just two of the winning images from the 2017 Nikon...
17-Jan-2018 12:05 PM EST Add to Favorites

Novel Combination Therapy Shown to Be Effective in Ovarian Cancer

Wistar researchers have found that combining PARP inhibitors, recently approved for the treatment of BRCA-mutant ovarian cancer, with another small molecule inhibitor was effective to treat ovarian cancers without BRCA1 and BRCA2 gene mutations.
19-Dec-2017 11:00 AM EST Add to Favorites

Scientists Identify Mechanism of Impaired Dendritic Cell Function that Weakens Immune and Therapeutic Response to Cancer

Wistar scientists revealed the mechanism implicated in the defective function of tumor-associated dendritic cells (DCs), a specialized type of immune cells that expose the antigens on their surface to activate the T cells
14-Dec-2017 3:10 PM EST Add to Favorites

Scientists Identified a Cellular Network That “Short Circuits” the Antitumor Effect of Novel Immunotherapy

Wistar researchers discovered a novel form of crosstalk among tumor cells and other cell types in the tumor microenvironment, elucidating the mechanism of action of an immunotherapeutic strategy that inhibits tumor-associated macrophages (TAMs) and...
10-Nov-2017 2:05 PM EST Add to Favorites

The Wistar Institute Awarded More Than $16.5M in Grants to Fund Cancer & Infectious Disease Research and Training

Wistar scientists have secured more than $16.5 million in funding throughout the summer and early fall of 2017.
6-Nov-2017 11:05 AM EST Add to Favorites

Wistar Expands Collaboration & Signs Exclusive License Agreement with Man’s Best Friend Therapeutics to Develop Novel Veterinary Vaccine Technology

The collaboration will further advance a canine melanoma vaccine and other vaccines for cancer and infectious diseases in animals
2-Nov-2017 9:00 AM EDT Add to Favorites

Genome Architecture Caught in Motion

Researchers at The Wistar Institute have uncovered new aspects of the three-dimensional organization of the genome, specifically how the genetic material is compacted and de-compacted in a timely fashion during the different phases of the cell cycle.
9-Oct-2017 11:05 AM EDT Add to Favorites

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