Major Grant Awarded to Wistar Supports Development of a Novel Therapeutic Approach for Antibiotic-resistant Bacteria

Wistar has received a grant of approximately $4.6 million from the National Institutes of Health in support of innovative research to tackle antibiotic resistance.
12-Sep-2019 3:05 PM EDT Add to Favorites

Repeated Semen Exposure Promotes Host Resistance to Infection in Preclinical Model of HIV

Contrary to the long-held view that semen can only act as a way to transmit HIV-1 from men to women, scientists at The Wistar Institute and the University of Puerto Rico found that frequent and sustained semen exposure can change the characteristics...
20-Aug-2019 4:05 PM EDT Add to Favorites

Novel Role in Spatial Chromosome Organization Identified for Frequently Mutated Cancer Protein

New research from The Wistar Institute sheds light on the function of the ARID1A protein, encoded by a gene that is among the most frequently mutated across human cancers.
22-May-2019 2:05 PM EDT Add to Favorites

Enhanced Anticancer Compound May Allow for Precise Activation and Tracking of Treatment

Wistar and the University of South Florida researchers have advanced a novel compound that specifically targets the endoplasmic reticulum (ER) stress response that is frequently hyperactivated in cancer and promotes survival of cancer cells during...
15-May-2019 12:05 PM EDT Add to Favorites

Wistar Earns ‘Exceptional’ Rating for NCI Cancer Center Support Grant for the Second Review Cycle in a Row, Demonstrating Strength of Science

The Wistar Institute’s Cancer Center has received an “exceptional” rating on its Cancer Center Support Grant (CCSG) application from the National Cancer Institute (NCI) for the second review cycle in a row and the grant has been recommended...
23-Apr-2019 10:00 AM EDT Add to Favorites

Synthetic DNA-encoded Antibodies Against Zika Virus Shown to be Effective in Preclinical Studies

New approach for delivery of DNA-encoded monoclonal antibodies (DMAbs) has been reported by Wistar scientists. This new technology allows direct production of monoclonal antibody-like molecules in living animals.
5-Apr-2019 11:05 AM EDT Add to Favorites

New Small Molecule Inhibitors Show Potential for Treatment of Epstein-Barr Virus-Associated Cancers

Researchers at The Wistar Institute have created a drug candidate for cancers associated with Epstein-Barr Virus (EBV), the virus that causes infectious mononucleosis.
5-Mar-2019 10:40 AM EST Add to Favorites

New Insight Into the Balance Between the Tumor-suppressive and Tumor-promoting Effects of Cellular Senescence

Researchers at The Wistar Institute have described a novel role of nicotinamide adenine dinucleotide (NAD+) metabolism in the ability of senescent cells to release tumor-promoting molecules.
18-Feb-2019 11:00 AM EST Add to Favorites

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