Wistar Expands International Training of the Next Generation of Scientists With the University of Bologna

Wistar and the University of Bologna (Unibo) in Italy have established the Wistar-Unibo Ph.D. Exchange Program in Cell and Molecular Biology to bring Unibo graduate students to Wistar for their three-year Ph.D. training.
27-Apr-2021 10:10 AM EDT Add to Favorites

Low-dose Administration of MERS DNA Vaccine Candidate Induces Potent Immunity and Protects From Virus Challenge in Preclinical Models

A synthetic DNA vaccine candidate for Middle East respiratory syndrome coronavirus (MERS-CoV) developed at The Wistar Institute induced potent immune responses and afforded protective efficacy in non-human primate (NHP) models when given...
22-Apr-2021 1:05 PM EDT Add to Favorites

Wistar Scientists Discover New Mechanism Through Which Senescent Cells Turn On Genes That Encode for Secreted Tumor-regulating Factors

Wistar scientists identified a new mechanism of transcriptional control of cellular senescence that drives the release of inflammatory molecules that influence tumor development through altering the surrounding microenvironment.
1-Apr-2021 10:00 AM EDT Add to Favorites

Richard M. Horowitz Appointed Chair of The Wistar Institute’s Board of Trustees

Wistar is pleased to announce the appointment of Richard M. Horowitz as chair of its Board of Trustees.
23-Mar-2021 3:05 PM EDT Add to Favorites

RNA Editing Protein ADAR1 Protects Telomeres and Supports Proliferation in Cancer Cells

Wistar scientists identified a new function of ADAR1, a protein responsible for RNA editing, discovering that the ADAR1p110 isoform regulates genome stability at chromosome ends and is required for continued proliferation of cancer cells.
12-Mar-2021 8:05 AM EST Add to Favorites

Wistar Scientists Make Pivotal Discovery on the Mechanism of Epstein-Barr Virus Latent Infection

Wistar researchers have discovered a new enzymatic function of the Epstein-Barr Virus (EBV) protein EBNA1, a critical factor in EBV’s ability to transform human cells and cause cancer. Published in Cell, this study provides new indications for...
21-Jan-2021 11:35 AM EST Add to Favorites

New Insights Into the Control of Inflammation

Wistar scientists discovered that EGR1 inhibits expression of pro-inflammatory genes in macrophages. The discovery expands the understanding of how macrophages are set off and deactivated in the inflammatory process, which is critical in many...
13-Jan-2021 2:10 PM EST Add to Favorites

Wistar Researchers Develop New Humanized Mouse Model That Provides Insight Into Immunotherapy Resistance

Wistar scientists have created an advanced humanized immune system mouse model that allows them to examine resistance to immune checkpoint blockade therapies in melanoma. It has revealed a central role for mast cells.
12-Jan-2021 8:45 AM EST Add to Favorites

See All News