Newswise — City of Industry, CA – May 18, 2015 – AIDP, today released a “Science White Paper” based on the peer-reviewed and published science, including a 2014 randomized, controlled trial from the University of California, Los Angeles UCLA), behind the mechanism of action, safety and efficacy of a new prebiotic ingredient, PreticX.1 The product is a Non-GMO prebiotic that has a GRAS status. It has been shown in clinical studies to significantly increase the proliferation of good gut bacteria, bifidobacterium at a very low dosage and thus a significant better tolerance profile as compared to other prebiotics.
Jennifer Gu, Ph.D., AIDP’s Vice President of Research and Development, said, “Advancing scientific research continues to demonstrate that balanced gut microbiota is essential for digestive function and that an unhealthy microbiota balance in the gut is a precursor to serious digestive issues and immune dysfunctions. The use of both prebiotic and probiotic products will continue to grow as consumers begin to understand that their digestive and immune function will decline gradually with age.
“PreTicX, a new prebiotic XOS, provides unique benefits including a low effective dosage, superior gastrointestinal safety, acid and temperature stability, and excellent taste profile. It has strong clinical data on its ability to increase healthy microflora as well as reduce biomarkers of certain health conditions. PreticX presents a compelling option in both foods and supplements to effectively target and promote gastrointestinal health.”
The 2014 UCLA study determined the tolerance and effects of prebiotic xylooligosaccaraides (XOS) to gut microbiota and whether these changes could be achieved without side effects. The study showed that bifidobacterium counts increased in both PreticX groups compared to the placebo subjects. Also significant, when the prebiotics were compared, researchers found that bifidobacterium favored XOS and confirmed findings from other human and animal studies, suggesting that XOS is an effective prebiotic that can change microbiota levels with a lower dose. PreticX is a non-GMO project verified oligosaccharides called xylooligosaccharides or XOS, PreticX has been clinically shown to increase bifidobacteria in the colon and aid in healthy digestion, with a low effective dose, making it a versatile and stable ingredient for use in both supplements and food products. The White Paper notes:• PreticX increases bifidobacterial as low as 1.4mg per day.• PreticX supplementation selectively activates beneficial but not harmful bacteria.• XOS significantly decreased serum triglyceride, cholesterol and glucose concentrations.• PreticX supplementation changes the microenvironment associated with obesity.• PreticX induced a favorable change in gut microbiota and biomarkers in Diabetic and pre-DM individuals.
Editor’s Note: A copy of the complete White Paper is available on request.
According to research firm Markets and Markets, The U.S Digestive Health Ingredients market has been segmented into prebiotics, probiotics and enzymes. The market is in the growth stage and is currently valued to be $265.9 million. It is expected to grow to $495.3 million in 2015 at a compound annual growth rate (CAGR) of 13.2%.2 The report states that the market dynamics and trends are very different among the three segments. Prebiotics and probiotics are growing at double-digit growth, and prebiotics is the largest revenue-generating ingredient among the three major segments.
Advancing scientific research continues to demonstrate that balanced gut microbiota is essential for digestive function, and that an unhealthy balance in the gut is a precursor to digestive issues, immune dysfunction and the development of disease. Consumers are beginning to better understand these concepts, and as they realize that their digestive and immune function will decline gradually with age, the use of both prebiotic and probiotic products will see continued momentum.
The development of products for healthy digestion is now focusing on prebiotic xylooligosaccharides to create a next generation of foods and supplements for optimal digestive support. PreticX, a new prebiotic XOS, is characteristic of these new more efficient ingredients and features strong clinical data on its ability to increase healthy microflora as well as reduce biomarkers of certain health conditions. PreticX presents a compelling option in both foods and supplements to effectively target and promote growth of specific gut bacteria that is already present in the large intestine, with an ingredient that is safe, efficacious, stable, and presents few side effects.
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AIDP is a leader in functional ingredients, with a focus on extensively researched products that meet consumer demand for wellness and healthy aging. Our commitment is to source high-quality ingredients and provide proprietary solutions that address formulation challenges. AIDP's success is grounded in its depth of experience and commitment to strong science for functional food and beverage product development.
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
1 Makelainen M, Saarinen M, Stowell J, Rautonen N, Ouwehand AC. Xylo-oligosaccharides and lactitol promote the growth of Bifidobacterium lactis and Lactobacillus species in pure cultures. Beneficial Microbes 2010 June: 1(2):139-148.