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Article ID: 702484

How Do Pelvic Floor Muscle Exercises Reduce Overactive Bladder Symptoms?

Wolters Kluwer Health: Lippincott Williams and Wilkins

Overactive bladder (OAB) is a common form of urinary incontinence that is widely treated with pelvic floor muscle (PFM) training. A new laboratory study lends insights into how PFM training works: by reducing contractions of the detrusor muscle of the bladder, reports the American Journal of Physical Medicine & Rehabilitation, the official journal of the Association of Academic Physiatrists. The journal is published by Wolters Kluwer.

19-Oct-2018 10:05 AM EDT

Article ID: 702287

NYU’s Brian Schmidt and Columbia’s Nigel Bunnett Awarded NIH Grant to Investigate the Role of Protease-Activated Receptors in Chronic Pain

New York University

The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), part of the National Institutes of Health (NIH), has awarded Brian Schmidt, DDS, MD, PhD, director of the Bluestone Center for Clinical Research at New York University College of Dentistry (NYU Dentistry) and Nigel Bunnett, PhD, professor in the Departments of Surgery and Pharmacology at Columbia University, a joint $2.7 million, 3.5-year grant to study Protease-Activated Receptor 2 (PAR2) and pain signaling. The study will help determine whether PAR2 can be exploited as a therapeutic target to treat chronic pain.

16-Oct-2018 12:05 PM EDT

Article ID: 702243

Marker May Help Target Treatments for Crohn’s Patients

Cornell University

Crohn’s disease (CD), a chronic inflammatory condition of the intestinal tract, has emerged as a global disease, with rates steadily increasing over the last 50 years. Experts have long suspected that CD likely represents a collection of related but slightly different disorders, but until now it has not been possible to predict accurately which subtype of CD a patient is likely to develop. In a study published Oct. 4 in the journal JCI Insight, Cornell University and University of North Carolina researchers report they have pinpointed a single molecule – microRNA-31 (miR-31) – the levels of which predict whether a patient has subtype 1 or subtype 2 of the disease.

15-Oct-2018 4:40 PM EDT

Article ID: 702042

Hernias: Why They Hurt and What Can Be Done

University of Alabama at Birmingham

“Every year, nearly 700,000 Americans have surgery for groin hernias.”

15-Oct-2018 7:05 AM EDT

Article ID: 702125

Obesity linked to increased risk of early-onset colorectal cancer

Washington University in St. Louis

Women who are overweight or obese have up to twice the risk of developing colorectal cancer before age 50 as women who have what is considered a normal body mass index (BMI), according to new research led by Washington University School of Medicine in St. Louis.

12-Oct-2018 12:05 PM EDT

Article ID: 702050

Researchers look beyond BMI to predict obesity-related disease risk

Scripps Research Institute

Predictors of future diabetes and cardiovascular disease for a person with obesity can be found among their body's metabolites.

11-Oct-2018 11:05 AM EDT

Article ID: 701966

Low Copper Levels Linked to Fatter Fat Cells

Johns Hopkins Medicine

In studies of mouse cells, Johns Hopkins researchers have found that low levels of cellular copper appear to make fat cells fatter by altering how cells process their main metabolic fuels, such as fat and sugar.

11-Oct-2018 8:00 AM EDT

Article ID: 701934

New study finds that inflammatory proteins in the colon increase incrementally with weight

Tufts University

A new study from Tufts researchers finds that two inflammatory proteins in the colon increase incrementally with weight. In individuals with obesity, this was accompanied by activation of precancerous cellular pathways.

10-Oct-2018 8:00 AM EDT

Article ID: 701893

Bug That Causes Stomach Cancer Could Play a Role in Colorectal Cancer

Duke Health

A bacterium known for causing stomach cancer might also increase the risk of certain colorectal cancers, particularly among African Americans, according to a study led by Duke Cancer Institute researchers.

9-Oct-2018 11:05 AM EDT

Article ID: 701864

Fred Hutch Cancer Research Tip Sheet

Fred Hutchinson Cancer Research Center

This month's tip sheet from Fred Hutch highlights research related to cancer-causing bacteria, a cancer 'escape hatch,' how sex cells sort chromosomes, cord blood's role in leukemia treatment and more.

8-Oct-2018 10:05 PM EDT

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