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Article ID: 700961

Study seeks to improve cancer survival for Latinos, Asians and Blacks

UC Davis Comprehensive Cancer Center

UC Davis Comprehensive Cancer Center has received a $6.3 million grant from the National Cancer Institute’s (NCI) Center to Reduce Cancer Health Disparities for a 5-year study to tease out why some ethnic and racial minority groups fare worse than whites when they get cancer and to find more precise treatments to improve their chances of survival.

Released:
21-Sep-2018 5:05 PM EDT

Article ID: 700904

Willow’s Strength: Parents Work with UTSW to Save Daughter From Deadly Metabolic Disease

UT Southwestern Medical Center

The family’s hope for Willow stems from a gene therapy center at UT Southwestern Medical Center where leading experts are engineering innovative treatments for some of the world’s rarest brain diseases.

Released:
21-Sep-2018 11:05 AM EDT
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  • Embargo expired:
    20-Sep-2018 11:00 AM EDT

Article ID: 700558

Scientists Grow Human Esophagus in Lab

Cincinnati Children's Hospital Medical Center

Scientists working to bioengineer the entire human gastrointestinal system in a laboratory now report using pluripotent stem cells to grow human esophageal organoids. The newly published research in the journal Cell Stem Cell is the first time scientists have been able to grow human esophageal tissue entirely from pluripotent stem cells (PSCs), which can form any tissue type in the body.

Released:
17-Sep-2018 6:00 AM EDT
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Article ID: 700808

Case Western Reserve’s Dr. Ahmad Khalil Receives NIH Funding to Develop New Paradigm in Fight against Colorectal Cancer

Case Western Reserve University

Certain genes that code for proteins have long been known to contribute to cancer progression. But in a frame shift, researchers from Case Western Reserve University School of Medicine recently found that non-coding genes also contribute to the development and spreading of the disease, one of the first known examples of researchers doing so. The lead author of the study reporting this finding, Ahmad Khalil, PhD, assistant professor of genetics and genome sciences at Case Western Reserve School of Medicine, has been awarded a five-year, $1.85 million grant from the National Institutes of Health to build on the discovery, with an eventual aim of pinpointing additional targets for cancer-fighting treatments.

Released:
20-Sep-2018 10:05 AM EDT
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  • Embargo expired:
    20-Sep-2018 9:00 AM EDT

Article ID: 700718

Detecting Epigenetic Signature May Help People Stay Ahead of IBD

Cincinnati Children's Hospital Medical Center

With an estimated 1.6 million people in the U.S. dealing with inflammatory bowel disease (IBD), physicians can have a hard time telling which newly diagnosed patients have a high risk of severe inflammation or what therapies will be most effective. Now researchers report in the journal JCI Insights finding an epigenetic signature in patient cells that appears to predict inflammation risk in a serious type of IBD called Crohn’s disease.

Released:
18-Sep-2018 1:00 PM EDT

Article ID: 700772

Anti-inflammatory Protein Promotes Healthy Gut Bacteria to Curb Obesity

University of North Carolina School of Medicine

UNC Scientists discovered the anti-inflammatory protein NLRP12 helps protect mice against obesity and insulin resistance when fed a high-fat diet. The researchers also reported the NLRP12 gene is underactive in people who are obese, making it a therapeutic target for treating obesity and diabetes.

Released:
19-Sep-2018 10:45 AM EDT

Article ID: 700780

Patient Groups and Doctors Tell Congress to Pass Medicare Virtual Colonoscopy Coverage

American College of Radiology (ACR)

Colorectal cancer care groups and the American College of Radiology are calling on Congress to pass the CT Colonography Screening for Colorectal Cancer Act (S.3465). The bipartisan bill introduced in the US Senate today would provide Medicare coverage for virtual colonoscopy.

Released:
19-Sep-2018 10:05 AM EDT
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Article ID: 700725

Researchers find adult stem cell characteristics in aggressive cancers from different tissues

University of California, Los Angeles (UCLA), Health Sciences

UCLA researchers have discovered genetic similarities between the adult stem cells responsible for maintaining and repairing epithelial tissues — which line all of the organs and cavities inside the body — and the cells that drive aggressive epithelial cancers. Their findings could bring about a better understanding of how aggressive, treatment-resistant cancers develop and progress, and could eventually lead to new drugs for a range of advanced epithelial cancers such as lung, prostate and bladder cancers.

Released:
18-Sep-2018 12:05 PM EDT
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  • Embargo expired:
    18-Sep-2018 11:00 AM EDT

Article ID: 700417

Solving the Gut Inflammation Puzzle

Sanford Burnham Prebys Medical Discovery Institute

Inflammatory bowel disease (IBD), an umbrella term for a number of gut disorders—including ulcerative colitis and Crohn’s disease—remains a clinical challenge. Now, researchers from Sanford Burnham Prebys Medical Discovery Institute (SBP), in collaboration with scientists at Technion – Israel Institute of Technology, have identified a protein that drives intestinal inflammation. This finding highlights new opportunities for creating targeted therapeutics. The study published today in Cell Reports.

Released:
17-Sep-2018 3:30 PM EDT

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