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Liver Fibrosis 'Off Switch' Discovered in Mice

University of California San Diego Health

UC San Diego School of Medicine researchers identified several genetic switches, or transcription factors, that determine whether or not liver cells produce collagen — providing a new therapeutic target for liver fibrosis.

Channels: Cell Biology, Digestive Disorders, Genetics, Liver Disease, All Journal News,

Released:
23-Jan-2020 1:45 PM EST
Newswise: Johns Hopkins Researchers: Climate Change Threatens to Unlock New Microbes and Increase Heat-Related Illness and Death

Johns Hopkins Researchers: Climate Change Threatens to Unlock New Microbes and Increase Heat-Related Illness and Death

Johns Hopkins Medicine

The Journal of Clinical Investigation (JCI) recently published “Viewpoint” articles by Johns Hopkins University School of Medicine professors who warn that global climate change is likely to unlock dangerous new microbes, as well as threaten humans’ ability to regulate body temperature.

Channels: All Journal News, Climate Science, Diabetes, Digestive Disorders, Environmental Health, Environmental Science, Immunology, Infectious Diseases, Public Health, Staff Picks,

Released:
22-Jan-2020 11:00 AM EST
Research Results
  • Embargo expired:
    21-Jan-2020 5:00 PM EST

Gut Bacteria May be One Culprit for Increase of Colorectal Cancer in Younger People

Georgetown Lombardi Comprehensive Cancer Center

A bacteria typically linked to periodontal disease, Fusobacterium nucleatum (F. nuc), could play an important role in the rising incidence of colorectal cancer in people under the age of 45. Another type of bacteria, Moraxella osloensis, has been found in colorectal cancer tumors at a nearly four-fold higher rate in people over 75 than in those under 45 years of age, pointing out how differences in the bacteria that comprise what is known as the body’s microbiome could affect cancer outcomes to varying degrees. These are the preliminary findings of an ongoing study that will be presented at the American Society of Clinical Oncology Gastrointestinal Cancers Symposium in San Francisco from January 23-25, 2020.

Channels: Cancer, Digestive Disorders, Healthcare, Microbiome, All Journal News,

Released:
20-Jan-2020 9:00 AM EST
Research Results
Newswise: Scurvy is still a thing in Canada

Scurvy is still a thing in Canada

McMaster University

McMaster University researchers surveyed the data of patients of Hamilton’s two hospital systems over nine years and found 52 with low Vitamin C levels. This included 13 patients who could be diagnosed as having scurvy, and an additional 39 who tested positive for scurvy but did not have documented symptoms. Among those with scurvy, some were related to alcohol use disorder or to bariatric surgery but the majority were related to other causes of malnutrition such as persistent vomiting, purposeful dietary restrictions, mental illness, social isolation and dependence on others for food.

Channels: Alcohol and Alcoholism, Blood, Digestive Disorders, Mental Health, Surgery, Local - Canada, All Journal News,

Released:
17-Jan-2020 4:55 PM EST
Research Results
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Acid reflux drugs may have negative side effects for breast cancer survivors

Ohio State University

Acid reflux drugs that are sometimes recommended to ease stomach problems during cancer treatment may have an unintended side effect: impairment of breast cancer survivors’ memory and concentration.

Channels: Cancer, Clinical Trials, Cognition and Learning, Digestive Disorders, Neuro, Pharmaceuticals, Women's Health, All Journal News, Staff Picks,

Released:
17-Jan-2020 10:25 AM EST
Research Results
Newswise: John Theurer Cancer Center Participating in Early-Phase Study of Immunotherapy-Boosting Treatment

John Theurer Cancer Center Participating in Early-Phase Study of Immunotherapy-Boosting Treatment

Hackensack Meridian Health

Investigators at John Theurer Cancer Center at Hackensack University Medical Center in New Jersey are participating in a first-in-patients clinical trial assessing VE800, a novel bacteria-containing therapy, in combination with the immunotherapy drug nivolumab. Laboratory research has suggested that VE800 may enhance the effectiveness of drugs like nivolumab.

Channels: Cancer, Digestive Disorders, Immunology, Liver Disease, Microbiome, OBGYN,

Released:
16-Jan-2020 1:55 PM EST
Research Results
Newswise: More Interventions Follow Gastric Bypass than Gastric Sleeve, Large Study Shows
  • Embargo expired:
    15-Jan-2020 11:00 AM EST

More Interventions Follow Gastric Bypass than Gastric Sleeve, Large Study Shows

Health Sciences at the University of Pittsburgh

A study involving tens of thousands of bariatric surgery patients found that gastric bypass patients were significantly more likely than gastric sleeve patients to end up back in the hospital in the years following surgery.

Channels: All Journal News, Digestive Disorders, Healthcare, Obesity, Surgery, Weight Loss, JAMA,

Released:
13-Jan-2020 12:00 PM EST
Feature
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New Closed-Loop System Offers Promise as Novel Treatment for Post-Bariatric Hypoglycemia

Joslin Diabetes Center

Post-bariatric hypoglycemia is a profoundly life-altering condition for patients. Having unpredictable hypoglycemia that people can't detect is really an unsafe situation. Researchers at Joslin Diabetes Center and Harvard John A. Paulson School of Engineering and Applied Sciences have developed a closed-loop system that automatically provides patients with an appropriate, as-needed dose of liquid glucagon to treat this condition.

Channels: Diabetes, Digestive Disorders, Healthcare, Surgery, Technology, All Journal News,

Released:
9-Jan-2020 2:25 PM EST
Research Results
Newswise: University of Colorado Cancer Center named National Pancreas Foundation Center of Excellence

University of Colorado Cancer Center named National Pancreas Foundation Center of Excellence

University of Colorado Cancer Center

Due in part to advanced surgical techniques, more effective medicines, and a multidisciplinary approach to treating the disease, University of Colorado Cancer Center is able to operate on 30+ percent of pancreatic cancer patients, nearly double the national average.

Channels: Cancer, Clinical Trials, Digestive Disorders, Healthcare, In the Workplace,

Released:
9-Jan-2020 8:05 AM EST
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