Feature Channels: Stem Cells

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Released: 5-Apr-2022 12:00 PM EDT
Nuclear inhibitor of protein phosphatase 1 (NIPP1) regulates CNS tau phosphorylation and myelination during development
Preprints

Cody McKee, Peter Shrager, Arindam Mazumder, Archan Ganguly, Abigail Mayer, Karl Foley, Nancy Ward, Margaret Youngman, Mathieu Bollen, Hailong Hou, Houhui Xia

Released: 5-Apr-2022 12:00 PM EDT
Transcriptional Heterogeneity and Cell Cycle Regulation as Central Determinants of Primitive Endoderm Priming
Preprints

Joshua M Brickman, Marta Perera, Silas Boye Nissen, Martin Proks, Sara Pozzi, Rita Soares Monteiro, Ala Trusina

Released: 5-Apr-2022 12:00 PM EDT
Mesenchymal Stem Cells Modified with Angiotensin Converting Enzyme 2 are Superior in Ameliorating Inflammation and Oxidative Stress in Diabetic Nephropathy
Preprints

Shasha Lv, Shanshan Liu, Yun Sun, Jing Cheng, Fulin Dou, Qiaoying Xu, Yinghui Wang, Qingzhen Liu, Gang Liu

Released: 4-Apr-2022 12:00 PM EDT
Low cost methods for Hydra care v2
Preprints

Callen Hyland, Jennifer DeSantis

Released: 4-Apr-2022 12:00 PM EDT
Identification of novel microcephaly-linked protein ABBA that mediates cortical progenitor cell division and corticogenesis through NEDD9-RhoA
Preprints

Aurelie Carabalona, Henna Kallo, Liliia Andriichuk, MaryAnne Gonzalez, Ellinoora Elomaa, Florence Molinari, Christiana Fragkou, Pekka Lappalainen, Marja Wessels, Juha Saarikangas, Claudio Rivera

Released: 4-Apr-2022 12:00 PM EDT
Methanol fixed feeder layers altered the pluripotency and metabolism of bovine pluripotent stem cells
Preprints

Wenqiang Xu, Ruifeng Hao, Jing Wang, Lingna Gao, Xuejie Han, Chen Li, Hui Zhang, Xueling Li

Released: 4-Apr-2022 12:00 PM EDT
Therapeutic options and clinical outcomes of 1261 patients with mantle cell lymphoma in China: a real-world retrospective multicenter analysis from Chinese Hematologist and Oncologist Innovation Cooperation of the excellent (CHOICE)
Preprints

Qingqing Cai, Dongfeng Zeng, Yu Fang, Yue Fei, Rong Liang, Haige Ye, Yun Liang, Xiuhua Sun, Michael Wang, Huiqiang Huang, Lugui Qiu, Tiejun Gong, Donglu Zhao, Yuxuan Che, Jinni Wang, Panpan Liu, Yi Wang, Tao Pan, Yao Lv, Panruo Jiang, Xuzhao Zhang, Jintai Deng, Shuhua Yi, Yizi He, Ling Xiao, Huijuan Lv, Jiangfang Feng, Huan Xie, Jiacheng Qian, Huilai Zhang, Hui Zhou

Released: 3-Apr-2022 12:00 PM EDT
Single-cell profiling of lncRNAs in human germ cells and molecular analysis reveals transcriptional regulation of LNC1845 on LHX8
Preprints

Nan Wang, Jing He, Xiaoyu Feng, Shengyou Liao, Yi Zhao, Fuchou Tang, Kehkooi Kee

Released: 1-Apr-2022 12:00 PM EDT
Multi-omic profiling of the leukemic microenvironment shows bone marrow interstitial fluid is distinct from peripheral blood plasma
Preprints

Lorenz Nierves, Jian Guo, Siyuan Chen, Janice Tsui, Anuli C Uzozie, Jonathan W Bush, Tao Huan, Philipp F Lange

Released: 1-Apr-2022 12:00 PM EDT
Fyn interrupts telomere maintenance in stem cells by phosphorylating menin at tyrosine 603
Preprints

Souren Paul, Preston McCourt, Le Thi My Le, Joohyun Ryu, Wioletta Czaja, Ann Bode, Rafael Contreras-Galindo, Zigang Dong

Released: 1-Apr-2022 12:00 PM EDT
CRISPR activation rescues abnormalities in SCN2A haploinsufficiency-associated autism spectrum disorder
Preprints

Serena Tamura, Andrew D Nelson, Perry We Spratt, Henry Kyoung, Xujia Zhou, Zizheng Li, Jingjing Zhao, Stephanie S Holden, Atehsa Sahagun, Caroline M Keeshen, Congyi Lu, Elizabeth C Hamada, Roy Ben-Shalom, Jen Q Pan, Jeanne T Paz, Stephan J Sanders, Navneet Matharu, Nadav Ahituv, Kevin J Bender

Released: 1-Apr-2022 12:00 PM EDT
Dynamic tissue-specific H2Bub1 is required for human and mouse cardiogenesis
Preprints

Syndi Barish, Jeffrey Drozd, Kathryn Berg, Isabella Berglund-Brown, Labeeqa Khizir, Lauren Wasson, Christine Seidman, Jonathan Seidman, Sidi Chen, Martina Brueckner

Released: 1-Apr-2022 9:00 AM EDT
In-vivo T-cell depleted reduced-intensity conditioned allogeneic haematopoietic stem-cell transplantation for patients with acute lymphoblastic leukaemia in first remission: results from the prospective, single-arm evaluation of the UKALL14 trial
The Lancet

Background The outcome of chemotherapy in patients older than 40 years with acute lymphoblastic leukaemia is poor and myeloablative allogeneic haematopoietic stem-cell transplantation (HSCT) has a high transplant-related …

Released: 31-Mar-2022 4:00 AM EDT
Substance P/neurokinin-1 receptor pathway blockade ameliorates limbal stem cell deficiency by modulating mTOR pathway and preventing cell senescence
Stem Cell Reports

… Autologous limbal stem cell transplantation is highly successful, but impossible in cases of complete bilateral stem cell deficiency. In these … We found that a very low amount of stem cell-like cells remained 4 weeks after the stem cell deficiency model …



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