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Newswise: Louis Justement and Mary-Ann Bjornsti begin leadership roles at FASEB
Released: 1-Jul-2020 2:50 PM EDT
Louis Justement and Mary-Ann Bjornsti begin leadership roles at FASEB
University of Alabama at Birmingham

Immunologist Louis Justement, Ph.D., begins his term as president of the largest coalition of biological and biomedical research associations in the United States, FASEB.

Newswise:Video Embedded uab-doctor-shares-her-experience-treating-coronavirus-patients-in-new-york
VIDEO
Released: 25-Jun-2020 6:25 PM EDT
UAB doctor shares her experience treating coronavirus patients in New York
University of Alabama at Birmingham

Winter volunteered to treat patients at New York-Presbyterian Weill Cornell Medical Center.

Newswise: The Parkinson’s disease gut has an overabundance of opportunistic pathogens
Released: 18-Jun-2020 4:25 PM EDT
The Parkinson’s disease gut has an overabundance of opportunistic pathogens
University of Alabama at Birmingham

A 2003 hypothesis says Parkinson’s disease is caused by a gut pathogen that could spread to the brain through the nervous system. No evidence was found until now; researchers report for the first time a significant overabundance of a cluster of opportunistic pathogens in the PD gut.

Released: 17-Jun-2020 3:30 PM EDT
Is a summer vacation safe for your family?
University of Alabama at Birmingham

Destinations are opening up for summer vacation, but does that mean it is safe to travel with your family? The most important consideration while traveling during COVID-19 is weighing the risk, says Curry Bordelon III, DNP, assistant professor in the University of Alabama at Birmingham School of Nursing.

Newswise: Genetic rescue of SHANK3 is potential therapy in rare forms of autism spectrum disorder
Released: 15-Jun-2020 3:05 PM EDT
Genetic rescue of SHANK3 is potential therapy in rare forms of autism spectrum disorder
University of Alabama at Birmingham

A mouse study by Craig Powell, M.D., Ph.D., and colleagues suggests that early genetic rescue may be a potential therapy in autism spectrum disorder, or ASD. Powell looked at one gene called SHANK3, whose alteration is seen in about 0.5 percent of ASD patients.

Newswise: Story of jailed 17th-century Iberian “mulatto pilgrim” told in new book by John K. Moore Jr.
Released: 12-Jun-2020 4:05 PM EDT
Story of jailed 17th-century Iberian “mulatto pilgrim” told in new book by John K. Moore Jr.
University of Alabama at Birmingham

The book tells the story of a man jailed for impersonating a priest in 1693 Spain, when he was likely trying to escape racial persecution. It gives readers a fascinating look at a centuries-old legal case against a man on pilgrimage and shows how Iberians of black-African ancestry faced discrimination and mistreatment.

Newswise: “Prescribing Art” course teaches med students to recognize bias and better address racial disparities
Released: 12-Jun-2020 4:05 PM EDT
“Prescribing Art” course teaches med students to recognize bias and better address racial disparities
University of Alabama at Birmingham

Can art help doctors better understand their patients and address racial disparities? An innovative collaboration at the University of Alabama at Birmingham uses art to help medical students hone their observational skills, in order to make more accurate diagnoses. “Prescribing Art: How Observation Enhances Medicine” is a partnership between the School of Medicine, the Abroms-Engel Institute for Visual Arts and the Birmingham Civil Rights Institute.

Newswise: Retinitis Pigmentosa Research Probes Role of the Enzyme DHDDS in This Genetic Disease
Released: 11-Jun-2020 3:45 PM EDT
Retinitis Pigmentosa Research Probes Role of the Enzyme DHDDS in This Genetic Disease
University of Alabama at Birmingham

Researchers who made a knock-in mouse-model of the genetic disorder retinitis pigmentosa 59, or RP59, expected to see retinal degeneration and retinal thinning. They surprisingly found none, calling into question the commonly accepted — though never proved — mechanism for RP59.

Newswise: Springing into action: The urgent COVID-19 research fund at UAB
Released: 11-Jun-2020 2:05 PM EDT
Springing into action: The urgent COVID-19 research fund at UAB
University of Alabama at Birmingham

Researchers faced the same time crunch — create a COVID-19 research proposal in just five days, to compete for emergency COVID-19 funding raised through UAB and generous business donors in Birmingham and Montgomery.

Released: 11-Jun-2020 12:05 PM EDT
Caring for Your Loved Ones with COVID-19 at Home
University of Alabama at Birmingham

UAB expert provides practical ways you can care for your loved ones who have been diagnosed with COVID-19 at home.Much has been reported about some of the most severe cases of COVID-19, but what about those who may be experiencing mild or lesser symptoms and are not in situations where they have to be hospitalized? How can spouses, parents or families take care of their loved ones at home?

Newswise: Complement genes add to sex-based vulnerability in lupus and schizophrenia
Released: 19-May-2020 7:10 AM EDT
Complement genes add to sex-based vulnerability in lupus and schizophrenia
University of Alabama at Birmingham

Variants in a gene of the human immune system cause men and women to have different vulnerabilities to the autoimmune diseases lupus and Sjögren’s syndrome, according to findings published in the journal Nature. The gene variants are a member of the complement system.

Newswise:Video Embedded sculptor-designs-builds-interactive-contraptions-from-everyday-materials-to-simulate-human-connections
VIDEO
Released: 14-May-2020 6:25 PM EDT
Sculptor designs, builds ‘interactive contraptions’ from everyday materials to simulate human connections
University of Alabama at Birmingham

Even in isolation, Stacey Holloway can hold a hand, receive a swift kiss on the cheek or give a high-five. She can offer a nose rub, just like the ones she shares with her mother. She just does them all alone — that is, if you don’t count the kinetic, prosthetic models she created to help.

Newswise: Precision medicine guides choice of better drug therapy in severe heart disease
Released: 14-May-2020 4:45 PM EDT
Precision medicine guides choice of better drug therapy in severe heart disease
University of Alabama at Birmingham

Is personalized medicine cost-effective? Researchers have answered that question for one medical treatment, genotype-guided antiplatelet therapy for acute coronary syndrome patients with PCI. Their study uses pharmacogenomics and economic analysis of real-world clinical data.

Released: 14-May-2020 2:10 PM EDT
Surplus antioxidants are pathogenic for hearts and skeletal muscle
University of Alabama at Birmingham

Oxidative stress can be pathological. Now researchers report that the other end of the redox spectrum, reductive stress, is also pathological. Reductive stress causes pathological heart enlargement and diastolic dysfunction in a mouse model.

Released: 12-May-2020 6:50 AM EDT
Keeping your eyes healthy during the coronavirus pandemic
University of Alabama at Birmingham

Experts from UAB’s School of Optometry and UAB Callahan Eye Hospital and Clinics provide guidance for keeping your eyes safe during the coronavirus pandemic.

Released: 11-May-2020 3:45 PM EDT
How high school seniors can navigate uncertainty during the coronavirus pandemic
University of Alabama at Birmingham

Angela Stowe, Ph.D., has advice for students leaving high school, and those about to start college, on bringing closure to their K-12 experience and preparing to move forward with their lives.For high school seniors bound for college, the COVID-19 pandemic struck at a pivotal time in life — as they finish one chapter and prepare to start a new one.

Newswise: Individualized mosaics of microbial strains transfer from the maternal to the infant gut
Released: 8-May-2020 3:55 PM EDT
Individualized mosaics of microbial strains transfer from the maternal to the infant gut
University of Alabama at Birmingham

A microbiome “fingerprint” method shows that an individualized mosaic of microbial strains is transmitted to the infant gut microbiome from a mother giving vaginal birth. The study analyzed existing metagenomic databases of fecal samples from mother-infant pairs and used a germfree mouse model.

Newswise: Smartphone-based automated contact tracing: Is it possible to balance privacy, accuracy and security?
Released: 7-May-2020 2:25 PM EDT
Smartphone-based automated contact tracing: Is it possible to balance privacy, accuracy and security?
University of Alabama at Birmingham

UAB professor, Nitesh Saxena, Ph.D., explains the context of contact tracing and how it will help the impact of the novel coronavirus pandemic.

Newswise: Grant will fund pilot program to expand opioid use disorder treatment in Alabama
Released: 6-May-2020 11:55 AM EDT
Grant will fund pilot program to expand opioid use disorder treatment in Alabama
University of Alabama at Birmingham

UAB is launching a pilot program aimed at getting more opioid users into treatment, using telemedicine in three rural counties and emploing the Alabama One Health Record®, a statewide health information exchange, to track outcomes in these patients.

Newswise: UAB biotechnology aids hunt for novel COVID-19 DNA vaccine
Released: 4-May-2020 4:55 PM EDT
UAB biotechnology aids hunt for novel COVID-19 DNA vaccine
University of Alabama at Birmingham

The Earle A. Chiles Research Institute is using the protein purification technology from TriAltus Bioscience to purify the spike protein of the COVID-19 virus. The protein will be used to measure the effectiveness of a new DNA vaccine, intended to evoke an immune response against the spike protein.

Newswise: Gender identity plays a role in the amount of pain experienced by individuals with chronic pain
Released: 1-May-2020 4:25 PM EDT
Gender identity plays a role in the amount of pain experienced by individuals with chronic pain
University of Alabama at Birmingham

Gender identity and genetic sex are distinctly variable when it comes to pain tolerance, according to a study published in the Journal of Pain Research.

Newswise:Video Embedded in-one-of-america-s-rare-undergraduate-immunology-programs-students-are-preparing-for-the-next-pandemic2
VIDEO
Released: 30-Apr-2020 1:05 PM EDT
In one of America’s rare undergraduate immunology programs, students are ‘preparing for the next pandemic’
University of Alabama at Birmingham

UAB's Undergraduate Immunology Program, one of a handful of immunology majors available in the United States, gives students real lab experience with more than 100 faculty pursuing cutting-edge research.The entire planet, more or less, is fixated on the greatest pandemic in modern memory. Claire Elliott is already preparing for the next one.

Newswise:Video Embedded coronavirus-may-damage-kidneys-impact-dialysis-supplies
VIDEO
Released: 27-Apr-2020 4:15 PM EDT
Coronavirus may damage kidneys, impact dialysis supplies
University of Alabama at Birmingham

. Ashita Tolwani, a nephrologist at the University of Alabama at Birmingham, explains how COVID-19 is impacting patients and putting a strain on the availability of dialysis supplies..

Newswise: Working behind the scenes: UAB pathologists play key role in fighting coronavirus pandemic
Released: 24-Apr-2020 12:05 PM EDT
Working behind the scenes: UAB pathologists play key role in fighting coronavirus pandemic
University of Alabama at Birmingham

Testing has been a major cause for concern worldwide ever since the pandemic began, but clinicians and researchers with UAB’s Department of Pathology have been working around the clock to make testing available for as many people as possible, making sure accurate results are available in a timely manner.

Newswise: Search for drugs effective against COVID-19 includes UAB and Southern Research
Released: 23-Apr-2020 3:05 PM EDT
Search for drugs effective against COVID-19 includes UAB and Southern Research
University of Alabama at Birmingham

The University of Alabama at Birmingham will join an international effort coordinated by Scripps Research to test drugs for COVID-19. The work centers around ReFRAME, a vast collection of drugs developed for other diseases that are already known to be safe for humans.

Newswise: rep_immuno_lab_ov_550px.jpg
Released: 17-Apr-2020 11:35 AM EDT
In one of America’s rare undergraduate immunology programs, students are ‘preparing for the next pandemic’
University of Alabama at Birmingham

There are only a handful of immunology majors offered at U.S. universities. A report last October by UAB researchers made the case for expanding these programs. Now faculty and students are seeing an explosion of interest.

Newswise: New boron material of high hardness created by plasma chemical vapor deposition
Released: 15-Apr-2020 3:55 PM EDT
New boron material of high hardness created by plasma chemical vapor deposition
University of Alabama at Birmingham

Researchers used microwave-plasma chemical vapor deposition to create thin crystal films of a novel boron-rich boron-carbide material that has 37 percent the hardness of cubic diamond and acts as an insulator. The new material’s properties were predicted from first-principles analysis.

Newswise: Making the Most of Your Groceries During the Coronavirus Pandemic
Released: 14-Apr-2020 4:00 PM EDT
Making the Most of Your Groceries During the Coronavirus Pandemic
University of Alabama at Birmingham

Tara Harman, RDN, has tips on how to stretch your groceries while saving money.

Released: 7-Apr-2020 4:10 PM EDT
UAB among first in the U.S. to offer clinical trial for the treatment of patients with severe COVID-19 using nitric oxide
University of Alabama at Birmingham

iNO has been used for the treatment of failing lungs, but it was also found to have antiviral properties against coronaviruses.The University of Alabama at Birmingham has been selected to begin enrolling patients in an international study assessing the use of inhaled nitric oxide (iNO) to improve outcomes for COVID-19 patients with severely damaged lungs.

Newswise: A direct protein-to-protein binding couples cell survival to cell proliferation
Released: 3-Apr-2020 3:20 PM EDT
A direct protein-to-protein binding couples cell survival to cell proliferation
University of Alabama at Birmingham

The regulators of apoptosis watch over cell replication and the decision to enter the cell cycle. Researchers now show a direct link between the protein MCL1 — a member of the BCL2 protein family known as the gatekeepers of apoptosis — and the cell-cycle checkpoint protein P18.

Newswise: UAB will test a COVID-19 vaccine candidate created by Altimmune Inc.
Released: 30-Mar-2020 9:00 AM EDT
UAB will test a COVID-19 vaccine candidate created by Altimmune Inc.
University of Alabama at Birmingham

The University of Alabama at Birmingham is launching a collaboration with the biopharmaceutical company Altimmune, Inc. for preclinical testing of a potential vaccine to prevent COVID-19 disease

Newswise: Kids, playgrounds, toys and sports equipment — why it is not safe during a pandemic
Released: 26-Mar-2020 12:50 PM EDT
Kids, playgrounds, toys and sports equipment — why it is not safe during a pandemic
University of Alabama at Birmingham

UAB expert Samisksha Raut, Ph.D., explains the importance of keeping kids away from playgrounds and from touching various toys and sports equipment during the COVID-19 pandemic quarantine.

Newswise: The director of NIH visits UAB as COVID-19 appears
Released: 24-Mar-2020 2:30 PM EDT
The director of NIH visits UAB as COVID-19 appears
University of Alabama at Birmingham

Francis Collins, M.D., Ph.D., director of the NIH, flew to Birmingham on Thursday, March 5, to start a long-anticipated visit to UAB. Collins soon learned he had a problem back home. Maryland public health officials were reporting the first two cases of COVID-19 in the county where the NIH sits.

Released: 23-Mar-2020 2:05 PM EDT
Eating right and eating smart during COVID-19
University of Alabama at Birmingham

Worry, stress and anxiety that naturally come with a global pandemic can lead to stress eating and cravings.

Newswise: COVID-19: Do not forget the host in treating this disease
Released: 16-Mar-2020 3:35 PM EDT
COVID-19: Do not forget the host in treating this disease
University of Alabama at Birmingham

From reading the literature primarily out of China, many of the severely ill coronavirus-infected patients appear to have clinical and laboratory features of a cytokine storm syndrome, or CSS, which is frequently fatal.

Newswise: rep_francis_collins_1000px.jpg
Released: 16-Mar-2020 10:30 AM EDT
Looking to the future with Dr. Francis Collins
University of Alabama at Birmingham

At a presentation at UAB, NIH director Francis Collins outlined the top 10 area of excitement and promise in science.

Newswise: Hydrogen sulfide heightens disease in tuberculosis, suggesting a new therapeutic target
Released: 3-Mar-2020 4:15 PM EST
Hydrogen sulfide heightens disease in tuberculosis, suggesting a new therapeutic target
University of Alabama at Birmingham

A new culprit — hydrogen sulfide — worsens the deadly disease tuberculosis. When Tb bacteria invade the lung, the amounts of hydrogen sulfide in the lung microenvironment greatly increase, and this makes the microbe more virulent and better able to block the body’s protective immune response.

Released: 2-Mar-2020 4:20 PM EST
Cast your ballot, not your germs
University of Alabama at Birmingham

Polling locations across the country employ different methods of casting ballots, like using pens, felt-tip markers or touch screens — all hotbeds for germs.

Released: 27-Feb-2020 5:30 PM EST
How to prepare in the event of a pandemic
University of Alabama at Birmingham

UAB experts provide tips for you to prepare yourself in the event of the spread of COVID-19.

Newswise: Cellular metabolism regulates the fate decision between pathogenic and regulatory T cells
Released: 25-Feb-2020 6:10 PM EST
Cellular metabolism regulates the fate decision between pathogenic and regulatory T cells
University of Alabama at Birmingham

Preclinical research shows a pivotal role for cellular metabolism to regulate the fate decision of CD4 T cells as they differentiate into either destructive Th17 cells that mediate chronic inflammation or regulatory Treg T cells, a decision that occurs very early in the activation of CD4 T cells.

Newswise: Lipid signaling from beta cells can potentiate an inflammatory macrophage polarization
Released: 21-Feb-2020 3:05 PM EST
Lipid signaling from beta cells can potentiate an inflammatory macrophage polarization
University of Alabama at Birmingham

The insulin-producing beta cells in the pancreas unwittingly produce a signal that may aid their own demise in Type 1 diabetes, according to a study of the lipid signals that drive macrophage cells in the body to two different phenotypes of activated immune cells.

Newswise: Study shows new surgical protective gear does not reduce surgical site infections
Released: 14-Feb-2020 3:20 PM EST
Study shows new surgical protective gear does not reduce surgical site infections
University of Alabama at Birmingham

A study from UAB published in JAMA Surgery on Feb. 12 indicates that use of surgical jackets and head covers known as bouffants in operating rooms does not reduce the incidence of surgical site infections.

Newswise: New pathogenic mechanism for influenza NS1 protein found
Released: 14-Feb-2020 11:15 AM EST
New pathogenic mechanism for influenza NS1 protein found
University of Alabama at Birmingham

Researchers report the biological effects of influenza protein NS1 binding to RIG-I — the binding directly quiets the alarm that activates the cellular innate immunity defense against the infection. This is a newly described way for flu to antagonize the host cellular antiviral response.

Released: 14-Feb-2020 9:00 AM EST
Love is in the air — or is it allergies?
University of Alabama at Birmingham

UAB allergist Ed Boyd, M.D., shares some tips to avoid any risk of allergic reactions.

Newswise: Injury study charts the unknown: Ultimate Frisbee
Released: 12-Feb-2020 9:55 AM EST
Injury study charts the unknown: Ultimate Frisbee
University of Alabama at Birmingham

Researchers at UAB have published the first look at injury rates of professional Ultimate athletes. As the flying disc sport surges in popularity, especially in children, understanding injury risk is vital.

Newswise: Link between chronic kidney disease and heart failure is identified in patients
Released: 3-Feb-2020 4:20 PM EST
Link between chronic kidney disease and heart failure is identified in patients
University of Alabama at Birmingham

People with chronic kidney disease have a higher risk for heart disease and heart-disease death. Now, for the first time in humans, researchers have identified a pathological change that appears to link kidney disease to progressive heart disease.


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