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Radiation therapists and physicians know that education can reduce anxiety before radiation treatment but lack a standardized tool. In an effort to solve this problem, a multidisciplinary team from Jefferson College of Health Professions and the Sidney Kimmel Cancer Center at Thomas Jefferson University conducted a pilot study to see if a virtual environment education program could reduce some of the anxiety their patients face. They published their results in the Journal of Radiation Oncology.

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More Americans than ever are turning to spiritual, meditative and religious retreats as a way to reset their daily life and enhance wellbeing. Now, researchers at The Marcus Institute of Integrative Health at Thomas Jefferson University show there are changes in the dopamine and serotonin systems in the brains of retreat participants. The team published their results in Religion, Brain & Behavior.

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Physician researchers at Thomas Jefferson University suspect that some cases of coronary artery spasm go unrecognized and are incorrectly treated with stents. The good news – there could be a simple fix to eliminate these unnecessary stenting procedures. The team published a case series in Catheterization and Cardiovascular Interventions.

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By pooling the data of several studies, Thomas Jefferson University researchers showed that a higher rate of IV fluids not only decreased C-section rates, but also shortened the overall length of labor by one hour, as well as shortened the pushing phase. The results were published online as an accepted article in Acta Obstetricia et Gynecologica Scandinavica.

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Researchers at Thomas Jefferson University have shown that the composition of the mitochondrial calcium portal (the protein that regulates when and how much calcium enters) is different depending on the organ in the body, and this difference allows mitochondria to tune their energy output by decoding a pattern of amplitude and/or frequency of calcium oscillations inside a cell. The results, published March 7 in the journal Cell Reports, could shed light on our basic understanding of organ health and disease.

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. Jefferson researchers pieced together the three-dimensional atomic structure of a doughnut-shaped protein that acts like a door or ‘portal’ for the DNA to get in and out of the capsid, and have now discovered that this protein begins to transform its structure when it comes into contact with DNA.

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To understand how metformin changes the biology of cancer cells, researchers at the Sidney Kimmel Cancer Center at Thomas Jefferson University tested tumor cells before and after metformin treatment in non-diabetic cancer patients. The pilot clinical trial results were published today in The Laryngoscope.

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Researchers at Thomas Jefferson University’s Sidney Kimmel Cancer Center discovered a cell-surface receptor highly expressed by cancerous and brain cells that directly and tightly binds progranulin. Importantly, the researchers also showed that this binding activates a cellular program that makes cancer cells more aggressive.

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How does a cancer cell burn calories? New research from Thomas Jefferson University shows that breast cancer cells rely on a different process for turning fuel into energy than normal cells. The results were recently published in the Journal of Biological Chemistry.

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A new method to determine how effectively immune cells kill their targets could help personalize immune therapies.

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Steroids for women at risk of preterm birth improve lung development and reduces risk of severe respiratory distress in babies.

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Trained community partners ensure follow-through on vaccination against hepatitis B virus (HBV).

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A multi-disciplinary group of clinician researchers working in the medical intensive care units (MICU) at Thomas Jefferson University Hospital found no significant difference in mortality of patients on two separate units; one staffed by nurse practitioners, the other by resident physicians. Both groups of patients were under the care of an attending physician.

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Comprehensive occupational therapy care requires a family-centered approach including treatment for the person with dementia and education for the caregiver. Clinical assessments exist to evaluate the capabilities of a person with dementia, but until now, occupational therapists did not have a validated instrument to gain understanding of the caregiver’s perceptions of the person with dementia’s abilities. Occupational therapist researchers at the Jefferson College of Health Professions at Thomas Jefferson University developed a first-of-its-kind tool to close this gap and published their findings in OTJR: Occupation, Participation and Health.

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Researchers from Thomas Jefferson University analyzed data from thousands of transplants and developed a scoring system for donor kidneys that they hope might expand the pool of available organs in two ways. They published their findings in the Annals of Transplantation.

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Researchers examine the biggest challenges for African American women after receiving breast cancer treatment.

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Researchers at Thomas Jefferson University found similar rates of obesity and high blood pressure readings in student-athletes as would be expected in the general adolescent population, which may suggest that participation in athletics does not protect against these conditions. They published their findings in The Journal of Pediatrics.

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Tuning cold plasma can either promote or inhibit bone formation.

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A new tool helps remove the emotion around choosing the right approach for prostate cancer

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Using a new tool, researchers can study localized reactive oxygen species signals that control mitochondrial function in health and disease.