Eighty percent of Americans over 50 say their primary care doctor hasn’t asked about their hearing in the past two years, and nearly as many haven’t had their hearing checked by a professional in that same time, according to a new national poll report.
Pharmaceutical companies get special protection from the FDA for orphan drugs aimed at rare diseases, but a study shows high spending for common diseases for some such drugs. Just 21% of the total dollars spent in 2018 on 15 top-selling partial orphan drugs went to the treatment of rare diseases, while more than 70% went to the treatment of common diseases.
The University of Michigan Rogel Cancer Center has named Sarah Hawley, Ph.D., M.P.H., associate director for training, education and career development. She will lead the center’s efforts to coordinate and enhance robust resources that support faculty, trainees and students interested in cancer research.
As large multi-cancer datasets become more important for predicting who may benefit from cancer drugs, a new model better accounts for potentially overlooked variation.
While most adults over 50 understand that overuse of antibiotics is a problem, and say they’re cautious about taking the drugs, a sizable minority have used antibiotics for something other than their original purpose, and appear to think the drugs could help treat colds, which are caused by viruses not bacteria.
Irregular sleep schedules can affect mood and risk of developing symptoms of depression according to a study of first-year medical residents that used Fitbits and smartphones.
Hospital care for COVID-19 has been free to most patients, but insurance companies may be ending that. A study of flu-related hospital bills suggests a coronavirus hospital stay could now cost patients $1,000 out of their own pocket, on average.
A third of parents say the COVID-19 pandemic has made it difficult to get dental care for their children. But some families may face greater challenges than others.
A urine test based on University of Michigan Rogel Cancer Center research could have avoided one third of unnecessary prostate cancer biopsies while failing to detect only a small number of cancers, according to a validation study that included more than 1,500 patients.
Smartphones have helped many people endure the pandemic. But apps and text-message systems can also help fight COVID-19, by alerting smartphone users about their exposures, helping them make a vaccination appointment and track vaccine reaction, and more.
Researchers have developed a personalized system to accurately detect suicidal youths.
People who have tested positive for COVID-19 should isolate themselves from the other people they live with. But a new poll suggests that nearly one in five older adults don’t have the ability to do this – and that there are disparities by race, ethnicity, income and health status.
A new potential biomarker raises concerns over the current standard for treating COVID-19 induced blood clots with high dose blood thinners.
Counties that score worst on measures of poverty, economic inequality, housing, food access, family structure, transportation, insurance and disability had far more cases and deaths from coronavirus in the first months of the pandemic.
Researchers uncovered how stanniocalcin-1, or STC1, works inside a tumor cell to block a cellular “eat-me” signal that typically triggers the immune system to produce T cells to fight the tumor. The findings provide a potential target to improve immune responses to cancer.
Engineers and oncologists teamed to develop a microfluidic chip capable of capturing the body’s natural killer immune cells to harvest their cancer-killing exosomes.
As surgeons balance the need to control their patients’ post-surgery pain with the risk that a routine operation could become the gateway to long-term opioid use or addiction, a new study shows the power of an approach that takes a middle way.
People who take opioid medications for chronic pain may have a hard time finding a new primary care clinic that will take them on as a patient if they need one, according to a new “secret shopper” study of hundreds of clinics across the country.
Some students are starting to return to face-to-face school after months of remote learning during the pandemic. Experts will address parents' top questions about the transition.
A meta-analysis of lupus finds the disease is less common than previously thought, but disproportionally affects women and racial and ethnic minorities of both sexes.
The study demonstrates that T cell activation increases intracellular trafficking via the endoplasmic-reticulum-to-Golgi pathway, and that a protein known as SEC23B — a subunit of the COPII complex — regulates T cells’ production of these important secretory proteins after activation. The work points toward a new potential therapeutic target for decreasing the severity of graft-versus-host-disease (GVHD), a potentially fatal complication of bone marrow transplantation.
Study finds NAD+ break down leads to multi organ scarring, providing now a previously undiscovered pathogenic role of the enzyme CD38 in disease scarring.
Three-quarters of parents in a new national poll think peers better understand teen challenges, compared to teachers or counselors in the school.
COVID-19 deaths are indeed different from other lung failure deaths, according to two recent studies, with 56% of COVID-19 patients dying primarily from the lung damage caused by the virus, compared with 22% of those whose lungs fail due to other causes. But, the researchers conclude, the kind of care needed to help sustain people through the worst cases of all forms of lung failure is highly similar, and just needs to be fine-tuned.
As the vaccination of older adults against COVID-19 begins across the country, new poll data suggests that many of them don’t yet have access to the “patient portal” online systems that could make it much easier for them to schedule a vaccination appointment. In all, 45% of adults aged 65 to 80 had not set up an account with their health provider’s portal system.
A new study analyzes the potential transmission risk of airborne respiratory pathogens during bystander-initiated cardiopulmonary resuscitation, or CPR.
Once viewed as a pediatric condition, patients with cerebral palsy are aging, but the health care system is not prepared to offer them the care they need.
Nearly half of summer camps surveyed by researchers didn’t have official policies requiring campers be vaccinated, according to findings led by Michigan Medicine C.S. Mott Children’s Hospital in JAMA Pediatrics. Of 378 camps represented, just 174 reportedly had immunization policies for campers and 133 (39%) mandated staffers be vaccinated.
As the vaccine becomes available to older adults, and case of COVID-19 surge, a list of key tips and relevant links for older adults about getting through this winter safely and healthily.
More than half of people who use medical marijuana products to ease pain also experience clusters of multiple withdrawal symptoms when they’re between uses, a new study finds. And about 10% of the patients taking part in the study experienced worsening changes to their sleep, mood, mental state, energy and appetite over the next two years as they continued to use cannabis.
A new study suggests that more than half of outpatient psychiatry patients whose appointments were suddenly converted to video or phone interactions by the pandemic will want to keep going with virtual mental health care even after the pandemic subsides. The convenience of seeing a provider without leaving home, and avoiding potential exposure to the coronavirus, factor heavily into this preference. So does a patient’s initial experience with seeing a provider virtually.
The main bioactive compound of ginger root lowers autoantibody production and helps halt disease progression in mice with antiphospholipid syndrome and lupus.
A new study finds that tumors in the liver siphon off critical immune cells, rendering immunotherapy ineffective. But coupling immunotherapy with radiotherapy to the liver in mice restored the immune cell function and led to better outcomes.
The same societal factors that have caused worse outcomes in cancer for some minority populations are now causing disparities in COVID outcomes. Potential policy changes could help reduce disparities and improve outcomes for both diseases.
By taking a lesson from prostate cancer, researchers now have a promising lead on a treatment for COVID-19. They found that, just like in prostate cancer, TMPRSS2 is regulated by the androgen receptor in the lungs. And notably, blocking the androgen receptor led to lower expression of TMPRSS2, which led to decreased coronavirus infection in mice and cellular models.
A new national poll gives a glimpse into parents’ greatest concerns about their kids in the pandemic-era. High on the top 10 list: overuse of social media and screen time, internet safety, unhealthy eating, depression and suicide and lack of physical activity.
In a recent survey, people who said social distancing and COVID-safety guidelines violated their personal freedoms responded more positively to these ideas when they felt a loved one might be at risk of severe illness for COVID-19.
A team of researchers studying COVID-19 patients and caregivers has compiled guidebooks based on their findings that could help others through their COVID journey.
Osteopontin is discovered as the culprit behind these patients’ main cause of death. However, a repurposed immunosuppressive drug may combat the pro-inflammatory protein.
A combination approach to treating a common subtype of glioma — which includes metabolic reprogramming and immunotherapy — led to complete tumor regression in 60% of study mice.
By studying the roles of an inflammatory protein and antibodies in chronic rejection after lung transplantation, researchers discover possibilities for new treatments.
Even before the pandemic, older Americans had concerns about seeking emergency care because of the costs they might face, the amount of time they might spend in the waiting room and more. But the risk of catching the novel coronavirus in the emergency department added to those worries, according to a national poll of people ages 50 to 80.
In the first months after their COVID-19 hospital stay, patients face a high risk of ongoing health problems, trips back to the hospital, and death, a growing number of studies has shown. But the first week and a half may be especially dangerous. A new study shows COVID-19 patients had a 40% to 60% higher risk of ending up back in the hospital or dying in the first 10 days , compared with similar patients treated at the same hospitals during the same months for heart failure or pneumonia.
The availability of COVID-19 vaccines will not necessarily result in people getting fully vaccinated, because the first vaccines require a second dose within a few weeks to get full protection. Mark Fendrick, M.D., has studied barriers to preventive health services and offers suggestions based on past research for how to ensure full vaccination.
A multi-institutional study finds that COVID-19 can be found in post-mortem corneal tissue, highlighting the importance of the donor screening process.
Anyone who’s on social media right now has probably seen them: Passionate pleas from health care workers, asking for the public to realize how bad the COVID-19 pandemic has gotten, and urging them to take steps to slow the spread of coronavirus. But do these first-person posts from the heart actually have any effect? A new study suggests so.
Physicians did not recognize side effects from radiation therapy in more than half of breast cancer patients who reported a significant symptom, a new study finds.
Three University of Michigan researchers say eye care accessibility around the globe isn’t keeping up with an aging population, posing challenges for eye care professionals over the next 30 years.
Researchers report the ability to improve safety and efficacy using a CRISPR-Cas9 variant known as miCas9.
Basic science research explores the effects of impaired glycine metabolism in nonalcoholic fatty liver disease – and how to potentially use glycine-based treatment to help people with NAFLD.
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