Researchers at the Institute for the Developing Mind at Children’s Hospital Los Angeles have analyzed current gene-disease findings to understand why people with neurodevelopmental and mental illness often have physical disorders.
A research team at Children’s Hospital Los Angeles has generated functional human and mouse tissue-engineered liver from adult stem and progenitor cells. Tissue-engineered Liver (TELi) was found to contain normal structural components such as hepatocytes, bile ducts and blood vessels.
Children’s Hospital Los Angeles (CHLA) has been recognized by the National Association of Epilepsy Centers (NAEC) as a Level 4 epilepsy center, providing the highest–level medical and surgical evaluation and treatment for patients with complex epilepsy.
This year, Pasadena Magazine's prestigious Top Doctors issue recognizes more than 200 physicians with privileges to practice at Children’s Hospital Los Angeles, a top-ranked U.S. pediatric academic medical center.
A team of researchers have published a paper in the early online edition of the journal Cancer that describes pulmonary outcomes among childhood cancer survivors. The study evaluates the impact of complications such as asthma, chronic cough, emphysema and recurrent pneumonia on daily activities.
With a little advance planning, going back to school can be a fun and exciting adventure for kids and parents. The specialists at Children’s Hospital Los Angeles (CHLA) have put together their top five tips to ensure parents and kids transition smoothly from summer vacation to the new school year.
Doctors, nurses and staff at Children’s Hospital Los Angeles (CHLA) got a special treat earlier this week – a sneak preview of the Quinceanera gowns worn by two very special patients – formerly conjoined twins Josie Hull and Teresa Cajas. The girls were famously separated at the skull in a surgery in 2002.
CHLA researchers report that glucose transporters, which transfer glucose from the blood to the brain, are inhibited by E. coli K1 during bacterial meningitis, leaving insufficient fuel for immune cells to fight off infection. Their findings may lead to a novel way of treating children with meningitis and reducing long-term neurological problems.
A study led by researchers at The Saban Research Institute of Children’s Hospital Los Angeles (CHLA) suggests that maternal HIV infection influences the microbiome of their HIV-uninfected infants. Their findings may account for some of the immunological and survival differences seen these children.
A new research study suggests that all babies with a known mutation for cystic fibrosis (CF) and second mutation called the 5T allele should receive additional screening in order to better predict the risk of developing CF later in life.
On behalf of their charitable foundation, investor Steven Cohen and his wife Alexandra have donated $3 million to Children’s Hospital Los Angeles (CHLA) in support of the hospital’s neonatal unit. In honor of the couple’s generous gift, the unit will be named the Steven & Alexandra Cohen Foundation Newborn and Infant Critical Care Unit.
Nancy Lee, RN, MSN, NEA-BC, will join Children’s Hospital Los Angeles (CHLA) as senior vice president and chief clinical officer (CCO), effective July 5, 2016.
Tracy Zaslow, MD, is the director of the Sports Concussion Program and medical director of the Sports Medicine Program. She is Board-Certified in pediatrics, and also fellowship-trained, with board certification in sports medicine. Her clinical interests include a spectrum of orthopaedic and medical conditions affecting young athletes, including sports-related concussion, overuse injuries and injury prevention.
With summer comes fun in the sun, beach outings, pool parties and outdoor adventures like camping, hiking, bicycling and skateboarding. What also comes is an increased risk for injuries and as such, an increased need for awareness. The specialists at Children’s Hospital Los Angeles have compiled a list of helpful guidelines to ensure that you and your family have an enjoyable and safe summer in the heat and in and around the water.
U.S. News & World Report today has ranked Children’s Hospital Los Angeles once again as one of the best children’s hospitals in the United States, and as the top pediatric medical center in California, in the 2016-17 survey of best children's hospitals.
Researchers at The Saban Research Institute of Children’s Hospital Los Angeles have identified a new genetic candidate for testing therapies that might affect fear learning in people with PTSD or other conditions. Results of the study have been published in the Journal of Neuroscience.
While it’s important for children of all ages to embrace the down time away from the high expectations and heavy workloads of being in school, summer is not necessarily the time to abandon a structured schedule and learning opportunities. Here are a few tips for families to follow to help make this summer season productive and enjoyable.
A study published in the journal Human Molecular Genetics by researchers at Children’s Hospital Los Angeles (CHLA) provides novel insights into the brain mechanisms underlying the insatiable hunger and subsequent obesity in patients with Prader-Willi syndrome.
Since the intestinal microbiome is an important regulator of gut health and immune function, a pediatric surgeon and principal investigator at Children’s Hospital Los Angeles , investigated how surgical treatment of certain pediatric intestinal diseases have a long-term impact on intestinal flora.
A new study led by researchers at Children’s Hospital Los Angeles and the Genetic Disease Screening Program of the California Department of Public Health sheds light on some of those genetic mutations and the impact for those who carry them.
Recognizing his decades of health care leadership, the Health Policy and Management Alumni Association of UCLA’s Fielding School of Public Health has selected Children’s Hospital Los Angeles President and CEO Paul S. Viviano as its 2016 Leader of Today Honoree.
Becker's Hospital Review announced that Children’s Hospital Los Angeles (CHLA) earned a coveted place in its 2016 edition of its list of "100 Great Hospitals in America."
Tommy Covington is the kind of caretaker that his colleagues admire and his patients and families adore. Covington, a soft-spoken, teddy-bear-like veteran, is a legend at CHLA where he works the night shift (7 pm to 7 am) on the hematology-oncology floor. He and the rest of the CHLA nursing staff will be celebrated during National Nurses Week, May 6-12.
LOS ANGELES (April 26, 2016) – The inaugural Children’s Hospital Los Angeles Make March Matter ™ campaign raised $1.3 million, the hospital announced Tuesday. The month-long initiative exceeded its $1 million fundraising goal thanks to 67 local businesses and corporate partners who rallied community participation to give in support of critical, lifesaving care for children in Los Angeles.
Researchers at The Saban Research Institute of Children’s Hospital Los Angeles (CHLA) have demonstrated that targeting survivin – a protein that inhibits apoptosis or cell death – enhances the effectiveness of chemotherapy in cells and mouse models of retinoblastoma (Rb).
What could be warmer and fuzzier than a cute dog? How about 20 of them gathered together at a ‘pawty’ to celebrate a milestone occasion? That’s what happened when Children’s Hospital Los Angeles declared Monday to be Dog Therapy Appreciation Day. The hospital’s Amerman Family Foundation Dog Therapy Program marked a first by providing 365 consecutive days of dog therapy to CHLA patients, families and staff. The last day without a therapy dog on the CHLA campus was April 10, 2015.
David E. Cobrinik, MD, PhD, of The Vision Center at Children’s Hospital Los Angeles (CHLA) has been awarded a four-year grant totaling $1.665 million from the National Eye Institute of the National Institutes of Health. The grant will support his study seeking to improve understanding of how cone photoreceptors develop.
Altered shedding of epithelial cells from the intestinal lining is associated with multiple disorders, ranging from IBD to colorectal cancer. Researchers at CHLA looked at ways shedding and cell regeneration are controlled in healthy intestine, and found that shedding is negatively regulated by EGF.
The Children’s Center for Cancer and Blood Diseases (CCCBD) at Children’s Hospital Los Angeles is one of the first sites in the world to offer a promising new investigational therapy to treat pediatric acute lymphoblastic leukemia (ALL).
Douglas Nordli, Jr., MD, has been named chief of the Division of Pediatric Neurology and co-director of the Neurosciences Center at Children’s Hospital Los Angeles (CHLA). Dr. Nordli will also serve as a vice chair of Neurology at the Keck School of Medicine of the University of Southern California.
Tracy C. Grikscheit, MD, of The Saban Research Institute of Children’s Hospital Los Angeles receives $7.1 million grant from the California Institute of Regenerative Medicine Translational Research program to develop a cellular therapy for the treatment of nerve disorders of the digestive system.
Children with a severe type of spina bifida have excess fat accumulation in their lower extremities. Researchers at Children’s Hospital Los Angeles determine that this excess fat tissue is within the muscle boundary may signify increased risk for metabolic disorders such as diabetes.
Researchers at Children’s Hospital Los Angeles studied 11 biomarkers associated with inflammation, bone loss and/or bone formation in about 450 individuals – assessed by sex and HIV status – to try to determine causes of this differential bone loss.
Fetal interventionists and pediatric cardiologists perform an “in utero atrial septal stent procedure” to open the atrium, allowing blood trapped in the lungs and left upper heart chamber of a HLHS fetus to flow back to the right side of the heart. The successful procedure was a first for the CHLA-USC Institute for Maternal-Fetal Health and a first for a Southern California hospital.
Robert Seeger, MD, division head for Basic and Translational Research of the Center for Cancer and Blood Diseases at Children’s Hospital Los Angeles (CHLA) has been selected for the 2016 Lifetime Achievement Award from the Pediatric Blood and Marrow Transplant Consortium (PBMC).
Children’s Hospital Los Angeles (CHLA) and Thermo Fisher Scientific have agreed to develop a next-generation sequencing (NGS)-based panel designed specifically for pediatric cancer research. The assay would be CHLA’s first NGS panel designed to target biomarkers associated with childhood cancers.
Investigators at The Saban Research Institute of Children’s Hospital Los Angeles have created a novel model for studying a lung disorder of newborn babies.
The Care+Cure initiatives of The Epilepsy Foundation of Greater Los Angeles have stated their intent to establish a $1.6 million endowment to fund The Pediatric Epilepsy Fellowship Program at Children’s Hospital Los Angeles (CHLA). This endowment, announced on International Epilepsy Day, will be used to launch a program in July 2016 that will train one epilepsy fellow every year in perpetuity.
Investigators at Children’s Hospital Los Angeles have found that significant bone loss – a side effect of chemotherapy for acute lymphoblastic leukemia (ALL) – occurs during the first month of treatment, far earlier than previously assumed. Results of the study will be available online February 4, in advance of publication in the journal Bone.
CHLA has named Jaclyn Biegel, PhD, a leading academic expert on pediatric brain tumors, rhabdoid tumors and cancer cytogenetics, as director of the Center for Personalized Medicine at CHLA.
An interdisciplinary research team at The Saban Research Institute of Children’s Hospital Los Angeles has found that body mass index (BMI) is an inadequate method for estimating changes in body fat and obesity in children with leukemia.
Researchers at Children’s Hospital Los Angeles have shown that an immunotherapy that until now has only been available to patients enrolled in research studies, is equivalent to the product that has been manufactured for commercial use and can be made available to all patients
Building on a 30-year, three-generation study of depressed individuals, their children and offspring, a study provides a better understanding of the familial risk for depression and the role neuroplasticity might have in increasing the risk of developing depression.
Financier and philanthropist Tom Gores and his wife Holly have made a $5 million commitment to establish a new pediatric allergy treatment center at Children’s Hospital Los Angeles.
Tracy Zaslow, MD, is the director of the Sports Concussion Program and medical director of of the Sports Medicine Program at Children's Hospital Los Angeles. She is Board-Certified in pediatrics, and also fellowship-trained, with board certification in sports medicine. Her clinical interests include a spectrum of orthopaedic and medical conditions affecting young athletes, including sports-related concussion, overuse injuries and injury prevention. Dr. Zaslow, a team physician for the L.A. Galaxy soccer team, understands the goals and challenges faced by young athletes because, like her patients, she grew up playing sports and still remains active in tennis, volleyball, running, hiking, yoga and skiing.
Children’s Hospital Los Angeles announces the availability of the EOS Imaging System, the first technology capable of providing head-to-toe images of patients in both 2D and 3D while using up to 90 percent less radiation than X-rays.
In the first study of its kind, researchers have shown that inadequate maternal iron intake during pregnancy exerts subtle effects on infant brain development. Their findings have been published online by the journal Pediatric Research.