Each summer, a select group of teenagers spend five weeks of their summer vacation to help children with cancer and other catastrophic diseases through the Volunteen Program at St. Jude Children’s Research Hospital. The annual program allows teens to explore career paths and develop leadership and team-building skills while helping patients.
A research team led by St. Jude Children’s Research Hospital scientists has identified a potential new target for treatment of the childhood eye tumor retinoblastoma. Their work also settles a scientific debate by showing the cancer’s cellular origins are as scrambled as the developmental pathways at work in the tumor.
Recognizing the important role brothers and sisters play in the healing process, St. Jude Children’s Research Hospital recently hosted Sibling Star Day, an event dedicated to celebrating the brothers and sisters of St. Jude patients.
St. Jude Children’s Research Hospital investigators have identified a signaling molecule that functions like a factory supervisor to ensure that the right mix of specialized T cells is available to fight infections and guard against autoimmune disease.
St. Jude Children’s Research Hospital scientists have identified a key immune system regulator, a protein that serves as a gatekeeper in the white blood cells that produce the “troops” to battle specific infections.
Bone marrow transplant survival more than doubled in recent years for young, high-risk leukemia patients treated at St. Jude Children’s Research Hospital, with patients who lacked genetically matched donors recording the most significant gains.
Ching-Hon Pui, M.D., an eminent leader in the research and treatment of pediatric leukemia at St. Jude Children’s Research Hospital, has been named the recipient of the 2011 Henry M. Stratton Medal from the American Society of Hematology.
The largest study yet of adult childhood cancer survivors found that the first cancer is just the beginning of a lifelong battle against different forms of the disease for about 10 percent of these survivors.
A dramatically better computer tool for finding the genetic missteps that fuel cancer has been developed by St. Jude Children’s Research Hospital – Washington University Pediatric Cancer Genome Project investigators. Researchers are using the new algorithm to help identify the chromosomal rearrangements and DNA insertions or deletions unique to cancer.
Brenda Schulman, Ph.D., of St. Jude Children’s Research Hospital is a joint winner of The Protein Society’s 2011 Dorothy Crowfoot Hodgkin Award. The award recognizes exceptional contributions in protein science, which profoundly influence the understanding of biology.
The multicenter Baby HUG trial led by St. Jude Children’s Research Hospital investigators shows hydroxyurea reduces the most common symptoms of sickle cell anemia in children, raising hopes the drug will ease complications and improve patient quality of life.
A national Childhood Cancer Survivor Study led by St. Jude Children’s Research Hospital investigators identifies potential new strategies for helping adults who survived childhood cancer improve memory, attention and related skills.
Kimberly Ovitt has been appointed senior vice president of public relations at St. Jude Children’s Research Hospital. Ovitt will oversee public relations and communication strategies for the hospital, an institution renowned for its research and treatment of childhood cancer and other catastrophic diseases.
St. Jude Children’s Research Hospital physician receives the Paul P. Carbone Award in International Oncology from the International Network for Cancer Treatment and Research for his efforts to improve childhood cancer survival rates across the globe.
Ching-Hon Pui, M.D., a world renowned leukemia physician and researcher at St. Jude Children’s Research Hospital, is the recipient of the 2011 Joseph H. Burchenal Memorial Award for Outstanding Achievement in Clinical Research from the American Association for Cancer Research.
St. Jude Children’s Research Hospital investigators use a novel model system to show how specific mutations can induce glioma formation in multiple regions of the brain and to begin studying patient response to a new generation of targeted therapies.
Despite dramatically improved survival rates for childhood acute lymphoblastic leukemia (ALL), relapse remains a leading cause of death from the disease. Work led by St. Jude Children’s Research Hospital investigators identified mutations in a gene named CREBBP that may help the cancer resist steroid treatment and fuel ALL’s return.
Work led by St. Jude Children’s Research Hospital scientists identified how cells flip a switch between cell survival and cell death that involves a protein called FLIP.
New research from St. Jude Children’s Research Hospital and the Children’s Oncology Group ties the genetic variation characteristic of Native American ancestry to higher odds cancer will return and highlights a strategy to ease the racial disparities in survival.
St. Jude Children’s Research Hospital has been recognized by FORTUNE magazine as one of the “100 Best Companies to Work For.”
More effective risk-adjusted chemotherapy and sophisticated patient monitoring helped push cure rates to nearly 88 percent for older adolescents enrolled in a St. Jude Children’s Research Hospital acute lymphoblastic leukemia (ALL) treatment protocol and closed the survival gap between older and younger patients battling the most common childhood cancer.
Work led by St. Jude Children's Research Hospital demonstrated for the first time that the most common malignant childhood brain tumor, medulloblastoma, is actually several different diseases, each arising from distinct cells destined to become different structures.
Investigators report no evidence of toxicity in the four hemophilia B patients enrolled to date in a gene therapy trial using a vector under development at St. Jude Children’s Research Hospital and UCL (University College London) to correct the inherited bleeding disorder.
Monthly blood transfusions combined with daily medication to remove the resulting excess iron remains the best approach for reducing the risk of recurrent strokes in young patients with sickle cell anemia, according to a preliminary analysis of a multicenter trial that includes St. Jude Children’s Research Hospital.
The Intensive Care Unit (ICU) at St. Jude Children’s Research Hospital has been recognized for the second consecutive year with the Beacon Award for Critical Care Excellence given by the American Association of Critical-Care Nurses (AACN). In 2009, the St. Jude ICU became Tennessee’s first ICU to win the honor.
St. Jude Children’s Research Hospital investigators have identified key components of a signaling pathway that controls the departure of neurons from the brain niche where they form and allows these cells to start migrating to their final destination.
In time for this year’s Great American Smokeout, St. Jude Children’s Research Hospital expands its smoking cessation efforts by offering free counseling and nicotine replacement therapy to survivors of childhood or adult-onset cancer.
Once a year cartoon characters, fairy princesses and action heroes gather at St. Jude Children’s Research Hospital as hundreds of employees work together to turn the hospital into a giant trick-or-treat trail for children battling cancer and other catastrophic diseases.
St. Jude Children’s Research Hospital has been named the recipient of the 2010 Omar N. Bradley Spirit of Independence Award, presented by the Independence Bowl Foundation.
With the help of the Child Life Program at St. Jude Children’s Research Hospital, 22 new pieces of art were revealed from 19 talented adolescent patients during the Teen Art Show. The artwork is on display in a hospital hallway that was transformed permanently into the Teen Art Gallery.
St. Jude Children's Research Hospital’s approach to care gives families and children an active role in decision-making, while enhancing communication throughout treatment.
Through the Legacy Beads Program at St. Jude Children’s Research Hospital, patients collect colorful, glass beads that represent their experiences during treatment for cancer or other catastrophic childhood illnesses.
A study led by St. Jude Children’s Research Hospital investigators links the muscle weakness and other symptoms of a rare neurodegenerative disease to a misstep in functioning of a normal protein, rather than its build-up inside cells.
St. Jude Children’s Research Hospital scientists uncover a novel pathway for regulating T lymphocytes that play very different roles in inflammation.
A medicine widely used to treat attention-deficit/hyperactivity disorder also provides long-term relief from the attention and behavior changes that affect many childhood cancer survivors, according to a multicenter trial led by St. Jude Children’s Research Hospital investigators.
St. Jude Children’s Research Hospital investigators have identified a novel structure in cells that serves as a control switch in the body’s system for eliminating damaged cells and also offers new therapeutic potential.
With its new expansion of the Pharmacogenomics Research Network (PGRN), the National Institutes of Health (NIH) awarded St. Jude Children’s Research Hospital a prestigious grant to focus on anticancer agent research in children. The five-year, $8.6 million grant is titled “PAAR4Kids—Pharmacogenomics of Anticancer Agents Research in Children.”
While September is Childhood Cancer Awareness Month nationwide, at St. Jude Children’s Research Hospital, the fight against this disease is a year-round mission. Doctors and scientists work to improve survival rates for childhood cancer and develop better, safer therapies.
St. Jude Children's Research Hospital dietitians help children with cancer maintain proper nutrition during treatment.
A large study focused on documenting the strength and fitness of childhood brain tumor survivors has found that many face health challenges as they age, according to St. Jude Children's Research Hospital investigators.
In an elementary school classroom, students are seated on the floor in a circle to create a cozy atmosphere that encourages sharing and talking openly. One of the students has important information to share with his classmates. With the help of St. Jude Children’s Research Hospital staff, he explains why he has missed so much school and why he sometimes has to cover his nose and mouth with a mask.
An international team led by St. Jude Children’s Research Hospital scientists has developed a new approach that uses genomic information from different species to understand the biology that drives the formation of these different cancer subtypes.
St. Jude Children's Research Hospital is ranked as one of the top institutions in the annual “Best Places to Work in Academia” list by The Scientist magazine.
Acclaimed virologist Robert Webster, Ph.D., of St. Jude Children’s Research Hospital, presented the 2010 Leeuwenhoek prize lecture, a prestigious recognition awarded by the Royal Society in London.
Childhood cancer survivors diagnosed later with non-melanoma skin cancer may be at increased risk for having a malignant tumor within 15 years, according to research led by St. Jude Children’s Research Hospital investigators.
Researchers from St. Jude Children’s Research Hospital and the Pediatric Brain Tumor Consortium (PBTC) presented today at the American Society of Clinical Oncology the findings of a pediatric brain tumor study using an experimental drug that targets the underlying genetic makeup of the tumor.
St. Jude Children’s Research Hospital has been named the nation’s top children’s cancer hospital in the 2010-11 Best Children’s Hospital rankings published in U.S. News & World Report.
Harvesting fruits, vegetables and herbs at the peak of freshness is a recipe for good taste, but it also offers higher nutritional value which is important to the patients and staff at St. Jude Children’s Research Hospital.
An international team led by St. Jude Children’s Research Hospital investigators today released data detailing the effectiveness of nearly 310,000 chemicals against a malaria parasite that remains one of the world’s leading killers of young children.
The most comprehensive analysis yet of the genetic imbalances at the heart of childhood brain tumors known as high-grade gliomas (HGGs) identified a cancer gene that is unusually active in some tumors and is now the focus of a St. Jude Children’s Research Hospital clinical trial.
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