Researchers at the UCLA Jonsson Comprehensive Cancer Center and UCLA School of Dentistry have identified a potential new combination therapy to treat advanced head and neck squamous cell carcinoma, the most common type of head and neck cancer.
A UCLA-led study has found that dermatopathologists, who specialize in diagnosing skin diseases at the microscopic level, are motivated both by patient safety concerns and by malpractice fears — often simultaneously — when ordering multiple tests and obtaining second opinions, with a higher proportion of these doctors reporting patient safety as a concern. When ordering additional microscopic tests for patients, 90% of the dermatopathologists surveyed cited patient safety as a concern and 71% of them reported malpractice fears. Similarly, when obtaining second reviews from a consulting pathologist or recommending additional surgical sampling, 91% cited safety concerns and 78% malpractice concerns.
Annabelle de St. Maurice, MD, MPH, co-chief infection prevention officer for UCLA Health, speaks on The Centers for Disease Control and Prevention's guide for youth sports to resume.
In response to the COVID-19 pandemic, UCLA Mattel Children’s Hospital launched an innovative project to support the emotional needs of children through a new AI powered robot. Robin’s technology enables the robot to build what is called associative memory — it recognizes a child’s emotions by interpreting his or her facial expressions and builds responsive dialogue by replicating patterns formed from previous experiences.
New UCLA research conducted in mice could explain why some people suffer more extensive scarring than others after a heart attack. The study, published in the journal Cell, reveals that a protein known as type 5 collagen plays a critical role in regulating the size of scar tissue in the heart.
Scientists discovered that histones act as an enzyme that converts copper into a form that can be used by the cells. The finding refutes earlier theories that copper spontaneously converts in the body into a usable state.
A UCLA-led study has found that in 2 of 3 states and jurisdictions with policies that require students entering school to receive the human papillomavirus vaccine, vaccination rates among 13-to-17-year-olds were significantly higher than in surrounding states without such policies.
As California prepares for a potential surge of COVID-19, there is a pressing need to determine how critical care resources should be allocated, especially if there is an extreme shortage of those resources.
Youth who are Black, Indigenous and people of color (BIPOC) that also identify as LGBTQ+ representation of sexual orientations and gender identities experience higher rates of social discrimination and isolation, including bullying, family rejection and a lack of social support. Here are ways that family and friends can support them.
States with the highest level of income inequality had a larger number of COVID-19-related deaths compared with states with lower income inequality. New York state, with the highest income inequality, had a mortality rate of 51.7 deaths per 100,000 vs. Utah, the state with the lowest income inequality and which had a mortality of 0.41 per 100,000.
UCLA scientists have developed a method for restoring oxygen-consumption activity to previously frozen mitochondria samples. By speeding up research, investigators hope to accelerate the diagnosis of people living with mitochondrial diseases and secondary disorders in which mitochondria play a key role, including diseases related to aging, metabolism and the heart.
Topics include the efficacy and safety of third-line treatment regimens in resource-limited settings, viral rebound rates after treatment interruption of modern ART, and whether a standardized frailty score can improve clinicians’ ability to estimate cardiovascular risk among older people with HIV.
Researchers from UCLA, Harvard Medical School and the University of Tokyo found that during a recent six-year period, homeless people in New York state were more likely to hospitalized and treated with mechanical ventilators for respiratory infections than people who are not homeless. These findings have implications for the COVID-19 pandemic.
UCLA researchers and colleagues have received a $13.65 million grant from the National Institutes of Health to investigate and further develop an immunotherapy known as CAR T, which uses genetically modified stem cells to target and destroy HIV.
Dr. Clara Lajonchere, deputy director of the Institute for Precision Health at UCLA Health, has been elected chair of the new California Precision Medicine Advisory Council.
In the June 11 issue of the New England Journal of Medicine, a team of UCLA physicians and scientists describes the first case of immune modulation being used to cure a severe and often fatal fungal infection. The team “retuned” a 4-year-old’s immune system so that it could fight off disseminated coccidioidomycosis.
UCLA Health has been granted permission from the Food and Drug Administration to use a 3D printed design for COVID-19 testing swabs. The effort was led by a fellow from the UCLA Biodesign program.
Researchers at the UCLA Jonsson Comprehensive Cancer Center analyzed gene-expression patterns in the most aggressive prostate cancer grade group — known as Gleason grade group 5 — and found that this grade of cancer can actually be subdivided into four subtypes with distinct differences. The findings may affect how people are treated for the disease.
A review of 56 randomized clinical trials finds that psychological and behavioral therapies may be effective non-drug treatments for reducing disease-causing inflammation in the body.
A UCLA research team has identified a new paradigm for understanding the regulation of the immune system, potentially paving the way for new approaches to treating infections and immune-related diseases such as type 1 diabetes and certain cancers.
A new study from researchers at the UCLA Jonsson Comprehensive Cancer Center helps explain how disruptions in genes can lead to the resistance to one of the leading immunotherapies, PD-1 blockade, and how new drug combinations could help overcome resistance to the anti-PD-1 therapy in a mechanistically-based way.
A team of researchers from the UCLA Jonsson Comprehensive Cancer Center and peer institutions has been awarded a $5.75 million grant from the National Cancer Institute to study the correlation between obesity, inflammation and pancreatic cancer. The scientists hope their findings may help people avoid getting this cancer.
A new UCLA study in zebrafish has identified the process by which air pollution can damage brain cells, potentially contributing to Parkinson’s disease.
UCLA researchers have launched a new clinical trial that uses a hormone suppresser commonly used to treat men with prostate cancer to help improve clinical outcomes for men infected with COVID-19.
The AIDS Clinical Trials Group (ACTG) has initiated a clinical trial to evaluate whether the drug combination hydroxychloroquine and azithromycin can prevent hospitalization and death from COVID-19.
For the first time in over a decade, scientists have identified a first-line treatment that significantly improves survival for people with hepatocellular carcinoma, the most common type of liver cancer.
Much attention has been paid to the devastating effects of COVID-19 on the lungs. But doctors are learning how the virus may affect other organs, including the brain.
An interdisciplinary team of researchers at the Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research at UCLA has developed a first-of-its-kind roadmap of how human skeletal muscle develops, including the formation of muscle stem cells.
To keep patients and health-care providers safe from COVID-19, while providing urgent treatment to stroke patients, extra precautions must be taken, according to new guidelines published in the journal Stroke.
UCLA Health initiative to unite Los Angeles with four key goals: raise the collective civic spirit, encourage responsible behaviors like maintaining good health, acknowledge the hardships that COVID-19 has presented and show gratitude to local MVPs and heroes.
UCLA researchers found that adding a drug once commonly used to treat schizophrenia to traditional radiation therapy helped improve overall survival in mice with glioblastoma, one of the deadliest and most difficult-to-treat brain tumors.
The David Geffen School of Medicine at UCLA is leading a project in collaboration with the University of Iowa Carver College of Medicine to study ways to reduce the risk for COVID-19 infection among emergency department workers.
UCLA is one of seven sites participating in a clinical trial investigating whether hydroxychloroquine, a commonly used anti-malarial and autoimmune drug, can prevent infection with COVID-19.
A new UCLA study suggests the general public does not fully grasp the meaning of the terms "futile treatment" or "potentially inappropriate treatment," although the concept is important to understand so that families can make fully informed decisions for their loved ones.
When the COVID-19 outbreak became a pandemic, and the scarcity of testing supplies became a crisis, the leaders of UCLA Biodesign saw the experience and background of Gabriel Oland, MD, as the ideal combination to help reinforce one link in the strained supply chain: the nasopharyngeal swabs used to collect patient specimens for testing.
Researchers from the UCLA Jonsson Comprehensive Cancer Center received a $2.8 million, five-year grant from the National Cancer Institute to help develop a blood-based test to improve the selection and prioritization for patients with liver cancer who need a liver transplantation.
Three researchers at the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA have received awards to pursue treatments and vaccines for COVID-19 from the California Institute for Regenerative Medicine, the state’s stem cell agency.
Un grupo de investigadores de la Universidad de California Los Ángeles (UCLA), ha desarrollado una aplicación web que permite a todo el mundo ayudar en la lucha contra el coronavirus.
UCLA researchers identify a possible new drug that could help prevent cognitive decline in people who undergo radiation therapy for brain tumors.
UCLA has joined a nationwide effort to study whether convalescent plasma collected from people who have recovered from COVID-19 may yield a treatment for the deadly virus.
n the years after 2014, when the Affordable Care Act’s health insurance marketplaces were established, low-income patients who underwent a surgical procedure saved an average of $601 in out-of-pocket spending and $968 in premium spending per year, compared to before the marketplaces existed. Those low-income patients also had a 35% lower chance of having catastrophic levels of household medical spending. However, for middle-income patients, spending levels were about the same before and after the marketplaces began.
A new national registry has been launched by specialists in obstetrics, gynecology and reproductive sciences at UCLA Health and the University of California, San Francisco, to determine COVID-19’s possible effects on pregnant women and newborns.
UCLA researchers have launched an app called Stop COVID-19 Together, which is designed to predict the spread of COVID-19 throughout the community and to assess the effectiveness of current measures in that community, including physical distancing. The app will build a map of possible hotspots where there may be a higher risk for accelerated spread of the disease.
UCLA Health is one of 75 sites around the globe participating in a clinical trial sponsored by the National Institutes of Health to test the effectiveness of a candidate anti-viral drug against COVID-19.
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