Pulmospheres, three dimensional multicellular spheroids composed of lung cells from individual patients, were shown to be effective in predicting the efficacy of medications for idiopathic pulmonary fibrosis, according to findings from UAB presented today in JCI Insight.
Cardiac muscle patches in this proof-of-concept research may represent an important step toward the clinical use of 3-D-printing technology, as researchers have grown heart tissue by seeding a mix of human cells onto a 1-micron-resolution scaffold made with a 3-D printer.
UAB and VICIS have each made major strides in developing next generation football helmets in response to the growing concussion crisis, and they have partnered to combine expertise and intellectual property to bring more effective helmets to the market.
Neurobiologist Lynn Dobrunz, Ph.D., has discovered a novel mechanism for how stress-induced anxiety — the type of experience that can produce post-traumatic stress disorder, or PTSD — affects circuit function in the hippocampus, the area of the brain where aversive memories are formed.
The first set of guidelines for the use of fMRI in pre-surgical evaluation of patients with epilepsy have been published in Neurology. The seven-year effort was conducted by a committee commissioned by AAN and led by UAB's Jerzy Szaflarski, M.D., Ph.D.
UAB surgeons performed 385 transplants in 2016, and more than 33,600 transplants were performed nationwide.
For women with a prior low transverse incision cesarean delivery, the decision to undergo a vaginal delivery or elect to have a repeat cesarean delivery has important clinical and economic ramifications.
UAB-led Research to appear in American Journal of Preventive Medicine.
The UAB study, an updated meta-analysis of the use of implantable cardioverter-defibrillators for non-ischemic cardiomyopathy, provides further support to the current American Heart Association and American College of Cardiology guidelines and challenges the recently published DANISH trial
For the first time in humans, it has been reported that eating early in the day lessens daily swings in hunger and changes the 24-hour pattern of fat oxidation and energy metabolism, which may aid in weight loss
A UAB study shows that evaluation from a vision specialist should be included in return-to-learn concussion protocols.
A new $6.8 million, automated lab in the UAB Department of Hospital Labs analyzes between 4,000 and 5,000 tubes of blood every night, providing information to help guide patient care, while keeping watch for abnormal test results that require immediate notification to clinicians.
UAB experts say having a plan , setting specific goals and keeping track of progress are great action items to keep in mind when making resolutions for the new year.
In an effort to bring awareness to the power and benefits of living organ donation, Hasberry, Kuykendall and Kuykendall’s son, Cade, will attempt to climb Mount Kilimanjaro in Tanzania, East Africa, in June 2017.
UAB is the only hospital in Alabama to perform 500 TAVR cases.
Divyank Saini is one of 17 UAB employees who interpret lab samples to determine whether living - and deceased -donor transplants are possible. But Saini wanted to do more, and he did, becoming a donor in the world’s longest kidney transplant chain.
Contrary to advertisements, bumper pads and stuffed animals are not part of a safe sleep environment for infants.
In a Cancer Research paper, researchers: 1) identify a biomarker enzyme associated with aggressive glioma brain tumors, 2) reveal the regulatory mechanism for that enzyme, and 3) demonstrate potent efficacy, using a mouse model of glioma, for a small molecule inhibitor they have developed.
Glenn Fleisig compiles biomechanical analysis from thousands of baseball players to find out what's behind the epidemic.
Mississippi man transplanted at UAB is only the eighth HIV-positive to HIV-positive transplant recipient in the United States since implementation of the HOPE Act.
UAB professor Sarah Parcak, Ph.D., has been named to the list for her innovations in the area of satellite archaeology.
Spread holiday greetings, not the flu, this season.
Funding from a National Eye Institute award to the UAB School of Optometry will advance eye care research.
Four teams of UAB researchers have been awarded National Science Foundation grants totaling $5.4 million for basic neuroscience research and new methods of environmental monitoring.
Cannabidiol oil, also known as CBD oil, reduces the frequency and severity of seizures in children and adults with severe, intractable epilepsy, according to findings presented by researchers from UAB at the American Epilepsy Society 70th Annual Meeting.
A ruptured abdominal aortic aneurysm is the 15th leading cause of death in the country, and the 10th leading cause of death in men older than 55.
Authors of a New England Journal of Medicine article recommend a new case be made for housing to end homelessness, emphasizing benefits and de-emphasizing problematic cost-savings arguments.
Three decades of clinical trials have changed the face of HIV/AIDS.
UAB taps Boni E. Elewski, M.D., to lead the Department of Dermatology.
Following hip fracture increases after a reduction in reimbursement rates for DXA scans led to fewer scans, a UAB physician joined other advocates and successfully lobbied to increase DXA scan reimbursements to better identify and reduce hip fractures.
Stefan Kertesz, M.D., says a better understanding of what caused and what sustains the opioid epidemic is needed among policymakers and physicians to best serve patients and address the crisis.
Investigators at UAB have presented the first case study of a patient experiencing a brain bleed following consumption of an energy drink.
Participating in yoga is relatively safe, according to a new study from UAB which was the first large scale analysis of yoga injuries. Yoga-related Injury rates are rising, especially in older participants.
Cooper will join Joseph Tector as co-director of UAB’s Xenotransplantation Program with their research geared toward using genetically modified pigs to facilitate kidney transplants in humans.
Scientists from around the world will gather at UAB in December to focus on HIV research and women, particularly collaborative research on women living with HIV and those at risk.
UAB registered dietitian Ashley Delk says to put away the stretchy pants and eat smart this holiday season.
In mouse experiments, researchers have shown how aging and excess dietary fat create signals that lead to heart failure after a heart attack. Clarifying the mechanism of this harmful pathway is important because nearly 5 million people in the United States suffer heart failure as an age-related disease following heart attacks.
Alabama Interagency Autism Coordinating Council has established regional networks throughout Alabama to centralize resources for those with autism spectrum disorder, and for their families.
Researchers have identified a key mechanism linking the master molecular clock in the brain to changes in the external firing activity of those circadian clock neurons. It involves the GSK3 kinase enzyme, which is also the target of mood-stabilizing drugs used to treat bipolar disorder.
Antibody VRC01 proves safe for individuals infected with HIV-1 but only modestly controls the virus in participants who stop receiving antiretroviral therapy.
UAB launches study to see if family caregivers for dementia patients can benefit and improve quality of life from learning strategies to alter care-resistant behavior, such as refusal to take a bath, take medicine, accept routine mouth care, abstain from alcohol or go to a medical appointment.
UAB researchers hope to establish Cialis as a therapeutic agent for pregnant women exposed to chlorine and bromine during industrial accidents or acts of terrorism.
Asthma caused by adult exposure to cockroach detritus is blocked in mice that were vaccinated as newborns with a particular bacteria, Enterobacter that expresses alpha-1,3-glucan molecules on its surface.
UAB doctors say stroke prevention treatments are not one-size-fits-all, and treatment options can be individualized using this hierarchical ranking.
According to the CDC, sports-related dental injuries account for more than 600,000 emergency room visits each year.
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