Performing systematic reviews of nutrition related topics raises unique challenges not often encountered in the field of medicine. In a new article, a team of researchers use specific examples to describe the steps, strengths, and limitations of systematic reviews relevant to nutrition and discuss the factors that impact the results.
Public health researchers from Tufts and colleagues are the first to report the possible role of nativity (place of birth) on asthma prevalence in a black population in the United States. The findings emerged unexpectedly from a community-based participatory survey related to asthma conducted in Dorchester, Massachusetts.
A Tufts University study of 355 non-diabetic elderly men and women found men who took a vitamin K supplement had less progression of insulin resistance over a period of three years compared to men not receiving vitamin K. Vitamin K did not appear to protect supplemented women from age-related increases in insulin resistance.
Michael Levin, who headed the Center for Regenerative and Developmental Biology at The Forsyth Institute and was on the faculty at Harvard School of Dental Medicine, has been named biology professor at Tufts University. He focuses on left-right asymmetry, bioelectrical controls of pattern formation, and how living systems learn and store information outside the brain.
Tufts researchers have linked several single nucleotide polymorphisms (SNPs) in the DNA of Puerto Rican adults to altered concentrations of blood homocysteine and folate and the content of uracil in blood DNA. These measures are indicators of altered folate metabolism, a putative risk factor for many diseases including cancer and neural tube defects.
Tufts University's Miriam E. Nelson, PhD, served as vice-chair of the advisory committee for the new Physical Activity Guidelines for Americans, written by the U.S. Department of Health and Human Services (HHS). Based on the advisory committee's report, the guidelines contain individualized recommendations for population subgroups including adults, older adults and children.
Souvaine is chair of the Department of Computer Science in Tufts University's' School of Engineering. Her specialty is computational geometry, a field which focuses on the design and analysis of algorithms for solving geometric problems.
Tufts University student and a faculty lecturer uncover what they believe is the world's oldest known full-body impression of a primitive flying insect, a 300 million-year-old specimen from the Carboniferous Period. Surprise discovery made in a most unlikely place - behind a suburban strip mall.
President Bush's military policies in Iraq, and Afghanistan will become grist for debate as his administration moves into its final months. The country will also reflect on his accomplishments and difficulties during eight years in office.
Barack Obama's lead in national polls has created a formidable challenge for John McCain. The race has taken on a combative tone and will likely become more contentious as November 4 approaches.
A B-vitamin-deficient diet caused cognitive impairment and cerebral vascular changes without evidence of neurodegeneration in mice. These findings provide new insight into the mechanisms that may underlie human age-related cognitive decline.
Tufts University scientists have shown that it is possible to design biologically active, biodegradable optical devices "“ made from silk and needing no refrigeration - with applications in medicine, health, the environment and communications. For example, edible optical sensors could detect harmful bacteria in produce, and be consumed right along with the food if it were safe.
Tufts University Professor Ayesha Jalal's book, "Partisans of Allah: Jihad in South Asia," provides cultural and historical context to jihadi ideals in South Asia, especially in the federally administered tribal areas (FATA) of Pakistan. In addition, she can comment on the Pakistan government's policy in FATA and U.S.-Pakistan relations.
New research links overeating and obesity with the brain system implicated in pleasure and addictive behaviors strengthening the argument that obesity could be approached as an addictive disorder. This is the first study to demonstrate that obesity predisposition is associated with impairments in all midbrain dopamine systems that are in place early in postnatal life.
Dr. Janice Reichert, Senior Research Fellow at the Tufts Center for the Study of Drug Development, has been named Editor-in-Chief of the newly created journal mAbs, the first international peer-reviewed journal of its kind, to focus exclusively on monoclonal antibodies.
Eileen T. Kennedy DSc, Dean of Tufts University's Gerald J. and Dorothy R. Friedman School of Nutrition Science and Policy announced the 3rd Annual Friedman School Symposium, a conference for nutrition professionals.
Long DNA sequences, or palindromes, change the shape of the molecule from double helix to hairpin-like formation, which causes replication to stall. Altered or stalled replication causes chromosomal breaking, resulting in cancers and diseases.
Tufts University students, faculty and staff are first college campus in Massachusetts to join an effort that will finance development of renewable energy projects in low-income communities across the state. School will also solicit donations to purchase renewable energy credits (REC's).
CIRCLE (the Center for Information and Research on Civic Learning and Engagement) has moved to the Jonathan M. Tisch College of Citizenship and Public Service at Tufts University. The move will strengthen research on youth civic and political engagement.
Tufts University has received federal funding to develop chemical robots that will be able to squeeze into spaces as tiny as 1 centimeter, then morph into something 10 times larger, and ultimately biodegrade. The "chembots" could access urban environments, tunnels, caves and debris fields, and carry out other risky operations in complex environments.
A new report co-authored by Manhattan Institute senior fellow Benjamin Zycher, and Joseph DiMasi, and Christopher-Paul Milne, researchers from the Tufts Center for the Study of Drug Development, examines case histories for thirty-five important pharmaceutical innovations.
Tufts University researchers and five Boston-area community groups received a 5-year, $2.5 million grant from the National Institutes of Health (NIH) to study the health effects of pollution exposure in neighborhoods adjacent to major highways.
Best known for its role in colorectal cancer, the protein adenomatous polyposis coli (APC) has recently been found to play an essential role in the nervous system. This new study provides novel insights into the molecular basis of neurological disorders such as Alzheimer's disease, mental retardation, schizophrenia, and autism spectrum disorders.
Using imaging techniques, researchers have revealed the dynamic processes that allow receptors to communicate with one another to stimulate the immune system. By understanding this "crosstalk" researchers expect to gain insights into autoimmune diseases such as multiple sclerosis.
In a study published in Nature, researchers at Tufts report that Smad proteins regulate microRNA (miRNA) processing. Understanding the role of Smad proteins enables researchers to investigate abnormal miRNA processing, a contributing factor in the development of cardiovascular disorders and cancer.
Tufts University researcher Bess Dawson-Hughes, M.D., chaired the committee that recently updated the National Osteoporosis Foundation (NOF) Clinician's Guide to Prevention and Treatment of Osteoporosis. The new Clinician's Guide incorporates the World Health Organization (WHO) absolute fracture prediction algorithm (FRAX®).
Researchers at Tufts University School of Medicine and the University of Western Ontario introduce a model for predicting infectious disease outbreaks that takes into account weather and other factors. Accounting for these factors creates a more accurate model for forecasting infectious disease outbreaks and designing early warning systems.
Veterinary medicine contributes $3.3 billion to the economies of New England"”and the region faces a shortage of as many as 658 veterinarians by 2014, according to a study released today by the Cummings School of Veterinary Medicine at Tufts University.
In an epidemiological study, Tufts University researchers identified trends of vitamin B6 status in a sample of the United States population based on measures of plasma pyridoxal 5'- phosphate (PLP) levels in the bloodstream. Some study participants demonstrated inadequate vitamin B6 status, despite consuming the Recommended Daily Allowance (RDA) of vitamin B6.
The Cummings School of Veterinary Medicine at Tufts University will confer its first Doctorate of Philosophy in Comparative Biomedical Sciences to a student whose work may one day prove vital to understanding why Martha's Vineyard has played host to an outbreak of tularemia since 2000. Zenda L. Berrada will graduate alongside 78 new doctors of veterinary medicine and 14 students from the Cummings School's Master of Science in Animals and Public Policy program on Sunday.
Tadpoles exposed to atrazine during an often overlooked growth phase named organ morphogenesis develop deformed hearts and kidneys, according to Tufts University research. Atrazine is widely used in the United States and is known to be harmful to amphibians in early and late developmental stages. But the research focuses on a critical third stage.
Researchers have established necrostatins as the first-in-class inhibitors of RIP1 kinase, a protein that can direct cells into necrotic death. The findings appear to provide a new avenue for drug development to prevent cell death related to acute disease events such as heart attack and stroke.
A philanthropic act by Boston technology pioneer and Tufts University graduate Frank Doble more than 40 years ago has resulted in a gift of $136 million, the largest in Tufts' history. Doble's generosity will allow the university to begin development of an interdisciplinary research lab and support financial aid. Tufts and Lesley University are sharing $272 million.
Tufts University Friedman School of Nutrition launches Master's Degree Program in Nutrition Science and Policy in Ras al Khaimah, United Arab Emirates.
The Internet allows parents to have easy access to information about childrearing, but a new study from Tufts University shows that as the digital divide narrows, a digital skills divide is now emerging across socio-economic lines. The research "examines socio-economic status (SES) differences in parents' Web use, skills, and satisfaction."
Tufts University researchers have literally expanded the visualization concept with a new 14-foot by 8-foot visualization wall that translates the most abstract, complex scientific concepts into eye-popping 3-dimensional images that are clearer and more precise than what most conventional systems can produce.
For the past 12 years, Tufts University Professor R. Bruce Hitchner has been involved in public policy initiatives in the Balkans region, especially in Bosnia and Kosovo.
Tufts University School of Medicine and Maine Medical Center today announce the establishment of a new partnership with a "uniquely Maine" curriculum. Medical students will spend their first two years at Tufts, then move to Maine Medical Center for the entire clerkship period in year three and portions of the monthly rotations in year four.
The prototype for the first fully soft-bodied robot - developed at Tufts University - will be part of an exhibition at New York's Museum of Modern Art. The exhibition will showcase some 200 examples of "disruptive innovation" created by scientists, researchers and designers from around the world.
The Rockefeller Foundation has awarded the Cummings School of Veterinary Medicine at Tufts University a grant to assess veterinary health services in Indonesia and consider how advanced training of Indonesian veterinarians can enhance Indonesia's capacity to prevent and control infectious diseases shared by animals and people.
Andrew Wilder, PhD, and Kate Sadler, MSc, have joined the Feinstein International Center at Tufts University. Wilder leads the center's research on politics and policies in countries in conflict. Sadler is the center's new senior researcher focusing on public nutrition in emergencies.
The Tufts Center for the Study of Drug Development announced today it will host a five-day course focusing on clinical pharmacology, drug development, experimental design, and regulation.
For many older Americans, another candle on their birthday cake means another prescription in their medicine cabinet. In a review article, clinicians from Tufts University School of Medicine offer specific steps that physicians and other healthcare providers can take to avoid overuse, misuse, and underuse of medication in older adults.
Neuroscience researchers demonstrate for the first time that brain-derived neurotrophic factor (BDNF) is an essential component of neural circuits which regulate body weight in adult mice and that its expression in two particular brain regions is required to suppress appetite.
Tufts University researchers have updated their Food Guide Pyramid for Older Adults to correspond with the USDA food pyramid, now known as MyPyramid. The Modified MyPyramid for Older Adults continues to emphasize a nutritionally adequate diet with specific emphasis on nutrient-dense food choices and the importance of fluid balance and regular physical activity for older adults.
Tufts University is replacing loans with scholarship grants for all undergraduates whose annual family income is below $40,000, starting with the class of 2011. The new program helped Tufts enroll the most socio-economically diverse class in its history in Sept. 2007.
In a study of adults aged 20 and over, researchers at Tufts University showed that homocysteine and methylmalonic acid are at much higher levels in individuals who have a combination of vitamin B12 deficiency and high blood folate levels than in individuals who are also vitamin B12 deficient but have normal folate levels.
Elderly adults at risk for physical disabilities are able to adhere to a regular program of moderate exercise for one year, a recent study of 213 men and women suggests. Improvements in physical function were greater in participants who reported 150 minutes or more per week of moderate intensity physical activity.
Tufts University researchers report that maintaining normal serum zinc concentration in the blood may help reduce the risk of pneumonia development in elderly nursing home residents. Study participants with normal serum zinc concentrations in their blood reduced their risk of developing pneumonia by about 50 percent.
Researchers have created a computer model called Pathogen Simulation (PathSim) to study the sometimes deadly Epstein-Barr virus (EBV), which infects greater than 90% of the world's population. By using PathSim to study EBV, researchers hope to determine why some infected patients fall ill while others show no symptoms.
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