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Released: 1-Dec-2022 6:05 AM EST
Women with Elevated Breast Cancer Risk Could See Mortality Benefit from Estrogen-Blocking Drugs
Lombardi Comprehensive Cancer Center at Georgetown University

While it has long been recognized that drugs that block the cancer-promoting activity of estrogen reduce risk of developing new breast cancers, a new computer modeling study led by researchers at Georgetown Lombardi Comprehensive Cancer Center and colleagues showed that these treatments could also reduce the risk of dying from the disease in women who are at high risk.

27-Nov-2022 4:05 PM EST
Study in mice suggests that expression of estrogen-related gene can impact post-menopausal breast cancer risk and prevention strategies
Georgetown University Medical Center

In a study using a first-of-its kind mouse model of aging that mimics breast cancer development in estrogen receptor-positive post-menopausal women, investigators at Georgetown Lombardi Comprehensive Cancer Center and colleagues have determined that over-expression, or switching on of the Esr1 gene, could lead to elevated risk of developing estrogen receptor-positive breast cancer in older women.

7-Nov-2022 1:00 PM EST
Mindfulness-Based Stress Reduction Is as Effective as an Antidepressant Drug for Treating Anxiety Disorders
Georgetown University Medical Center

A guided mindfulness-based stress reduction program was as effective as use of the gold-standard drug -- the common antidepressant drug escitalopram -- for patients with anxiety disorders, according to results of a first-of-its-kind, randomized clinical trial led by researchers at Georgetown University Medical Center.

22-Sep-2022 4:50 PM EDT
Advanced Melanoma Survival Improves Significantly When Immunotherapy is Given Before Targeted Therapy
Lombardi Comprehensive Cancer Center at Georgetown University

A clinical trial led by clinicians at Georgetown Lombardi Comprehensive Cancer Center showed a remarkable 20 percent advantage in the two-year overall survival rate for people with advanced melanoma who first received immunotherapy (72 percent survival rate) versus those who initially got targeted therapies (52 percent survival rate). Progression-free survival, where the cancer is stable or improving, was also trending in favor of those who started on immunotherapy.

9-Sep-2022 3:05 PM EDT
Technique Developed in Mice Could Aid Detection of Cancer in Dense Breasts
Georgetown University Medical Center

A two-pronged approach to imaging breast density in mice, developed by researchers at Georgetown Lombardi Comprehensive Cancer Center, resulted in better detection of changes in breast tissue, including spotting early signs of cancer. The researchers hope that this approach will be translated from mice and improve breast imaging for people; it may also help with prognosis of disease as density can be linked to specific patterns of mammary gland growth, including signs of cancer development.

   
Released: 10-Aug-2022 8:00 AM EDT
NSF Awards Georgetown University $12.5M to Establish Institute for Emerging Virus Research
Georgetown University Medical Center

The National Science Foundation has awarded Georgetown University $12.5 million to lead a global team of scientists in establishing a collaborative institute designed to advance research and education around viral emergence -- the process of viruses jumping from animals to humans.

Released: 28-Jul-2022 8:05 AM EDT
Georgetown Awarded $23.6M to Study Treatments for Acute Rhinosinusitis
Georgetown University Medical Center

The Patient-Centered Outcomes Research Institute (PCORI) has awarded a Georgetown University Medical Center research team led by Dan Merenstein, MD, professor of family medicine at Georgetown’s School of Medicine, $23.6 million in research funding to study treatments for acute rhinosinusitis.

18-Jul-2022 1:45 PM EDT
Informing Children of a Mother’s Genetic Cancer Risk Does Not Impact Their Health Behaviors
Georgetown University Medical Center

Telling a child about their mother’s risk of hereditary breast and ovarian cancer does not adversely influence the offspring’s lifestyle or quality of life in the long term, according to a new study led by researchers at Georgetown Lombardi Comprehensive Cancer Center.

Released: 26-May-2022 1:05 PM EDT
Guidance for Talking To Children Following the Elementary School Shooting in Texas
Georgetown University Medical Center

The news out of Uvalde, Texas, where an 18-year-old man gunned down 19 innocent children and two adults and left several critically injured at an elementary school, has left many parents and caregivers wondering how to talk to their children about their safety.

Newswise: New study finds climate change could spark the next pandemic
Released: 28-Apr-2022 9:55 AM EDT
New study finds climate change could spark the next pandemic
Georgetown University Medical Center

As the earth’s climate continues to warm, researchers predict wild animals will be forced to relocate their habitats – likely to regions with large human populations – dramatically increasing the risk of a viral jump to humans that could lead to the next pandemic.

   
Released: 15-Nov-2021 5:05 PM EST
Trial Stopped Early: Giving Immunotherapy Before Targeted Rx Improves Survival in Advanced Melanoma
Georgetown University Medical Center

More people with advanced melanoma survive for two years or more when they receive a combination of two immunotherapy drugs given before a combination of two targeted therapies, if needed, compared to people who start treatment with targeted therapies.

11-Nov-2021 1:35 PM EST
Vascular Defects Appear to Underlie the Progression of Parkinson’s Disease
Georgetown University Medical Center

In an unexpected discovery, Georgetown University Medical Center researchers have identified what appears to be a significant vascular defect in patients with moderately severe Parkinson’s disease. The finding could help explain an earlier outcome of the same study, in which the drug nilotinib was able to halt motor and non-motor (cognition and quality of life) decline in the long term.

19-Oct-2021 6:05 AM EDT
Survey of US Dentists Shows High Rate of Opioid Prescriptions Despite Knowledge of Effective Alternatives
Georgetown University Medical Center

A survey of dentists in the United States finds that an overwhelming majority of those who responded believe nonsteroidal anti-inflammatory drug (NSAID)-acetaminophen combinations are as effective or more effective in managing dental pain as opioids; however, almost half say they still prescribe opioids.

18-Oct-2021 8:05 AM EDT
Starting Mammography at Age 40 Would Reduce Disparities in Deaths for Black Women
Lombardi Comprehensive Cancer Center at Georgetown University

If Black women begin mammography screening every other year starting at age 40, breast cancer deaths could be reduced by 57 percent compared to starting screening 10 years later — as is currently recommended by some organizations — according to analyses conducted by a modeling team that is part of the Cancer Intervention and Surveillance Modeling Network (CISNET), funded by the National Cancer Institute.

16-Sep-2021 2:05 PM EDT
For the First Time, Stroke Study Reveals Optimal Timing and Intensity for Arm and Hand Rehabilitation
Georgetown University Medical Center

A phase II, randomized clinical trial found that the optimal period for intensive rehabilitation of arm and hand use after a stroke should begin 60 to 90 days after the event. The study, conducted by Georgetown University and MedStar National Rehabilitation Network (NRH) researchers, published September 20, 2021, in PNAS.

27-Aug-2021 9:05 AM EDT
Insights into how a stroke affects reading could help with rehabilitation
Georgetown University Medical Center

Georgetown University researchers, looking at the ability of people to sound out words after a stroke, found that knowing which region of the brain was impacted by the stroke could have important implications for helping target rehabilitation efforts.

Released: 23-Aug-2021 10:45 AM EDT
Statement from Jesse L. Goodman, MD, MPH, on FDA Approval of Pfizer-BioNTech’s COVID-19 Vaccine
Georgetown University Medical Center

Today, the US Food & Drug Administration approved the two-dose COVID-19 Pfizer-BioNTech vaccine. Jesse L. Goodman, MD, MPH, professor of medicine and infectious diseases at Georgetown University Medical Center and former FDA Chief Scientist comments. (Audio file available)

16-Aug-2021 8:20 AM EDT
Key Mental Abilities Can Actually Improve During Aging
Georgetown University Medical Center

It’s long been believed that advancing age leads to broad declines in our mental abilities. Now new research from Georgetown University Medical Center offers surprisingly good news by countering this view.

10-Jun-2021 12:20 PM EDT
Small Numbers of Cells in a Tumor Could Be Key Enablers of Cancer Metastasis
Lombardi Comprehensive Cancer Center at Georgetown University

Just a small number of cells found in tumors can enable and recruit other types of cells nearby, allowing the cancer to spread to other parts of the body, report Georgetown Lombardi Comprehensive Cancer Center scientists. Working with their research collaborators, the scientists found that ‘enabler cells’ comprise about 20 percent or less of the cells in an aggressive tumor; their small numbers may account for why they are often missed when bulk tissue analyses are used to inform therapeutic decisions.



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