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10-Jul-2018 1:00 PM EDT
XaTek Inc. raises $9.1 million to advance ClotChip, a hand-held device to quickly gauge blood’s clotting ability
Case Western Reserve University

XaTek Inc., a Cleveland-based company developing a portable sensing system that can quickly assess the clotting ability of a person’s blood, recently raised $9.1 million in Series A capital to further advance and test the device, called ClotChip.

Released: 9-Jul-2018 2:05 PM EDT
Researchers Discover Llama-Derived Nanobody Can Be Used as Potential Therapy for Hard-to-Treat Diseases
Case Western Reserve University

Researchers from Case Western Reserve University School of Medicine have found a nanobody that holds promise to advance targeted therapies for a number of neurological diseases and cancer.

Released: 28-Jun-2018 3:05 PM EDT
Men and Women have Different Genetic Risk Factors for Developing Brain Cancer
Case Western Reserve University

Glioma is the most common type of primary malignant brain tumor in the United States; glioblastoma being the most common type of glioma in adults. While sex differences in the incidence and survival rates of glioma were known, researchers had not investigated whether genetic differences based on sex could cast light on potential differences in the risk profile of glioma between men and women. Now, a team from Case Western Reserve University School of Medicine, together with an international consortium of researchers, have discovered that men and women have different genetic risk factors for developing glioma.

Released: 14-Jun-2018 1:05 PM EDT
Case Comprehensive Cancer Center Partners with Nation’s Top Cancer Centers to Endorse Elimination of HPV-related Cancers in U.S.
Case Western Reserve University

Nearly 80 million Americans – one out of every four people – are infected with human papillomavirus (HPV). And of those millions, more than 31,000 will be diagnosed with an HPV-related cancer this year. Despite those staggering figures and the availability of a vaccine to prevent the infections that cause these cancers, HPV vaccination remains low in the U.S. Case Comprehensive Cancer Center has partnered with 69 other National Cancer Institute (NCI)-designated cancer centers to issue a statement urging increased HPV vaccination and screening to eliminate HPV-related cancers, starting with cervical cancer.

Released: 14-Jun-2018 1:05 PM EDT
New Study of Youth Hospitalizations Finds 24 Percent of Behavioral-Related Admissions Complicated by Suicidality or Self-Harm
Case Western Reserve University

A recent study published in American Psychiatric Association’s Psychiatric Services journal found previous research on youth hospitalizations associated with behavioral and mental disorders failed to adequately consider children exhibiting suicidality or self-harm. Previous studies assigned behavioral health disorders, such as depression, as the primary diagnosis, while identifying suicidality or self-harm as a secondary diagnosis. By looking closely at the data, the new study found that nearly 24 percent of all behavioral-related admissions are complicated by suicidality or self-harm.

Released: 11-Jun-2018 3:45 PM EDT
Researchers Identify Dozens of New Gene Changes That Point to Elevated Risk of Prostate Cancer in Men of European Descent
Case Western Reserve University

As the result of a six-year long research process, Fredrick R. Schumacher, PhD, a cancer epidemiology researcher at Case Western Reserve University School of Medicine, and an international team of more than 100 colleagues have identified 63 new genetic variations that could indicate higher risk of prostate cancer in men of European descent. The findings, published in a research letter in Nature Genetics, contain significant implications for which men may need to be regularly screened because of higher genetic risk of prostate cancer.

Released: 6-Jun-2018 12:05 PM EDT
Case Western Reserve Bioinformatics Expert Part of International “A” Team that Debuts Brain Cancer Atlas
Case Western Reserve University

It takes an “A” team to make headway against glioblastoma, a highly aggressive type of brain cancer. Glioblastoma is the most common type of malignant brain tumor in adults. In addition to the caliber of the researchers involved, in this case “A” also stands for atlas. A key member of the team, Jill S. Barnholtz-Sloan, PhD, Sally S. Morley Designated Professor in Brain Tumor Research at Case Western Reserve University School of Medicine, and approximately 80 other internationally renowned neurologists, bioinformaticians, and pathologists from the United States and India recently published details of the Ivy Glioblastoma Atlas in Science.

Released: 5-Jun-2018 2:05 PM EDT
Case Western Reserve University School of Medicine Researchers Create First Artificial Human Prion
Case Western Reserve University

Case Western Reserve University School of Medicine researchers have synthesized the first artificial human prion, a dramatic development in efforts to combat a devastating form of brain disease that has so far eluded treatment and a cure. The new findings are published in Nature Communications.

   
Released: 21-May-2018 8:05 AM EDT
Preventing Murder by Addressing Domestic Violence
Case Western Reserve University

Researchers at Case Western Reserve University found 45 percent of victims were at high risk for homicide and severe assault, in a one-year assessment

   
Released: 18-May-2018 10:05 AM EDT
Federal Judge: Prison Officials May Not Forcibly Cut Rastafarian Inmate’s Dreadlocks, Violate His Religious Freedom
Case Western Reserve University

A team of aw students prevailed in a federal lawsuit arguing that an Ohio inmate should be allowed to keep his dreadlocks, protecting his religious freedom.

Released: 16-May-2018 12:05 PM EDT
Colon Cancer Cells Use Mysterious RNA Strands to Avoid Cell Death
Case Western Reserve University

Researchers from Case Western Reserve University School of Medicine have discovered how unusually long strands of RNA help colon cancer cells avoid death, allowing unregulated growth. Unlike other RNAs, the intriguing strands do not appear to encode proteins and are termed “long non-coding RNAs” or “lincRNAs.”A new study showed some lincRNAs could be targeted by drug developers to halt colon cancer.

Released: 15-May-2018 8:00 AM EDT
Corporate Social Responsibility Programs Tend to Dehumanize the Very People They Expect to Help: New Research
Case Western Reserve University

Corporate programs aimed at offsetting the negative societal impacts caused by their profit-seeking tend to devalue the very people they intend to help.

Released: 14-May-2018 12:05 PM EDT
Heart Disease Severity May Depend on Nitric Oxide Levels
Case Western Reserve University

The most common heart medications may get an assist from nitric oxide circulating in the body, according to a new study out of Case Western Reserve University School of Medicine. Researchers showed that nitric oxide may help commonly used heart drugs maximize their benefits while improving heart function. In turn, the study found nitric oxide deficiencies could underlie heart failure while tilting drug effects toward more harmful pathways and side effects.

Released: 2-May-2018 9:05 AM EDT
Heart Disease Symptoms Improved by Blocking Immune Cell Migration
Case Western Reserve University

New research led by investigators at Case Western Reserve University School of Medicine and University Hospitals Cleveland Medical Center suggests that the location of immune cells in the body determines whether they help or harm the development of heart disease. The study supports the view that the immune system directly impacts heart failure—still the leading cause of death for men and women in the United States.



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