Mapping potential pathways to MND treatment
University of QueenslandFor the first time, researchers from The University of Queensland (UQ) have mapped out the proteins implicated in the early stages of motor neurone disease (MND).
For the first time, researchers from The University of Queensland (UQ) have mapped out the proteins implicated in the early stages of motor neurone disease (MND).
Ciprofloxacin is the first-line drug for treating typhoid fever in many countries in Africa with a high disease burden, but the emergence of non-susceptibility poses a challenge to public health programmes.
Cycles of a diet that mimics fasting can reduce signs of immune system aging, as well as insulin resistance and liver fat in humans, resulting in a lower biological age, according to a new USC Leonard Davis School of Gerontology-led study.
Any drug that is taken orally must pass through the lining of the digestive tract. Transporter proteins found on cells that line the GI tract help with this process, but for many drugs, it’s unknown which of those transporters they use to exit the digestive tract.
Published today in Nature Climate Change, the study found that exported used vehicles generate at least 13-53% more emissions per mile than those that are scrapped or on the road in Great Britain.
Fish exposed to some pesticides at extremely low concentrations for a brief period of time can demonstrate lasting behavioral changes, with the impact extending to offspring that were never exposed firsthand, a recent study found.
Buprenorphine, a life-saving medication for opioid use disorder, is far less accessible in geographic areas of the United States with racially and ethnically diverse populations than in predominantly white areas, according to a new study of pre-pandemic data led by health policy scientists at the University of Pittsburgh School of Public Health published today in Journal of Addiction Medicine.
Our immune system is remarkably powerful. It quickly assembles teams of cells to eliminate threats inside our bodies.
Researchers at Umeå University in Sweden, led by Professor Felipe Cava, have identified a new family of enzymes that creates a unique type of cross-linking between the building blocks of bacterial cell walls. This discovery could help develop new antibiotics against infectious diseases.
Many of Finland’s newly established wellbeing services counties are looking to cut costs in eldercare services, especially in round-the-clock care and home care.
Contrary to previous research suggesting that expressing anger in the workplace leads to higher status and positive outcomes, a new study by researchers from Hebrew University of Jerusalem and Princeton University found that expressing anger is not a catalyst for higher status in the workplace.
High-income communities overrepresented in relevant datasets for immunotherapy research.
Melatonin treatment does not affect the insulin resistance or the glucose tolerance of night shift workers, according to a new study from the University of Surrey and the University Medical Centre Hamburg. Melatonin treatment does, however, significantly improve the sleep quality of those working shifts.
Preferential trade agreements enable Norway to import large quantities of meat from Africa. This may undermine climate change mitigation in the agricultural sector.
Higher income countries must move away from unfair data practices that undermine African researchers, writes Nicki Tiffin.
How does our intestine, which can be at least 15 feet long, fit properly inside our bodies? As our digestive system grows, the gut tube goes through a series of dramatic looping and rotation to package the lengthening intestine.
The reproduction of giant sea spiders in Antarctica has been largely unknown to researchers for more than 140 years, until now.
Dr. Yamamoto et al. found the several uremic toxins as one of causes of itching in hemodialysis patients.
Researchers from Tokyo Metropolitan University crafted replica stone age tools and used them for a range of tasks to see how different activities create traces on the edge.
Two innovative design techniques lead to substantial improvements in performance in fractional-N phase locked loops (PLLs), report scientists from Tokyo Tech.
As part of a nationwide collaboration, Broad Clinical Labs researchers have optimized 10 polygenic scores for use in clinical research as part of a study on how to implement genetic risk prediction for patients.
University of Pittsburgh School of Medicine researchers discovered a molecular mechanism by which excessive dietary protein could increase atherosclerosis risk.
The prospect of the worrisome triple threat of COVID, RSV and flu was assuaged last year by the effectiveness of flu vaccines.
In a group of plants that is famous for luring its pollinators into a death trap, one species offers its flowers as a nursery in exchange.
A rapid scoping review has been conducted which reveals five common ways in which the health of homeless pet owners and their companion animals is improved. Ten percent of homeless people keep pets. But little information exists on specific interventions.
UMass Amherst researcher co-leads worldwide efforts to understand how genetic variants are linked with disease to develop new drugs and treatments.
Nuclear power is considered one of the ways to reduce dependence on fossil fuels, but how to deal with nuclear waste products is among the issues surrounding it.
Neuroscientists at Macquarie University in Australia have developed a single-dose genetic medicine that has been proven to halt the progression of both ALS and frontotemporal dementia (FTD) in mice – and may even offer the potential to reverse some of the effects of the fatal diseases.
A 280-million-year-old fossil that has baffled researchers for decades has been shown to be, in part, a forgery following new examination of the remnants.
Self-monitoring of physical activity with an accelerometer and feedback is an effective tool to improve physical activity in elderly people requiring long-term support.
An innovative and more efficient way to produce fumaric acid that not only reduces carbon dioxide emissions, but also reuses waste resources to make biodegradable plastics.
A revolutionary nanomaterial with huge potential to tackle multiple global challenges could be developed further without acute risk to human health, research suggests.
Despite the pronounced seasonality in their habitat, the bacterial community in Arctic sediments is taxonomically and functionally very stable.
The random information posted online could be used to generate information about biodiversity and its conservation.
A team at the University of Seville has studied trends in the flowering date of around fifty plant species over the last 35 years in Doñana National Park.
Scientists still are not sure how neurological symptoms arise in COVID-19.
Applying plasma technology increases efficiency by 3-fold. Confirmation of a novel approach for lithium extraction from brine.
Neuroscientists from Bonn, New York, and Freiburg discover interactions between so-called "ripples" and nerve cells during human memory processes.
Having a heart attack significantly increases the risk of developing other serious long-term health conditions, a major new study shows.
The study, published in 'One Earth', is the first to analyse the interplay of electrification and hydrogen in EU climate neutrality scenarios at greater sectoral detail.
Increasing access to water in extremely arid parts of sub-Saharan Africa can help nomadic livestock farmers in the short term.
The efficiency of oxygen supply to tissues is a factor in the severity of important diseases such as Covid-19 and heart conditions.
Delays in diagnosing melanoma due to Covid-19 lockdowns may have contributed to over 100,000 years of life lost across Europe and over £6bn in costs, mainly indirectly due to loss of productivity, finds a new study led by UCL and University Hospital of Basel researchers.
Parents of young children with an excitable or exuberant temperament could adapt their parenting style to help moderate their child’s potential development of Attention Deficit/Hyperactivity Disorder (ADHD), according to a new study co-authored by a University of Waterloo researcher.
Researchers report in the journal Cell that ancient viruses may be to thank for myelin—and, by extension, our large, complex brains.
A team co-led by Southwest Research Institute found evidence for hydrothermal or metamorphic activity within the icy dwarf planets Eris and Makemake, located in the Kuiper Belt.
Newcastle University has assisted in finding cost-efficient methods for the NHS to improve the care and quality of life for care home residents.
You’d think the complex flavor in a quality cup of tea would depend mainly on the tea varieties used to make it.
Back in 1981, Tom Petty sang that the waiting is the hardest part. New research from The University of Texas helps to explain why.
It is not uncommon for people to “hit the wall” at work and experience burnout for short or long periods of time.