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Released: 18-May-2010 8:45 AM EDT
Study Looks at Major Advances in Pediatric Epilepsy Surgery at UCLA Over Two Decades
University of California, Los Angeles (UCLA), Health Sciences

A new study from the UCLA Pediatric Epilepsy Surgery Program found that surgery at UCLA to treat catastrophic pediatric epilepsy has improved over the past two decades and has led to more successful outcomes, including freedom from seizures. The researchers credit improvements in diagnostic technology and experience in selection and operations as reasons for the program's success.

Released: 18-May-2010 8:45 AM EDT
PET Scanning Probes Reveal Different Cell Function Within the Immune System
University of California, Los Angeles (UCLA), Health Sciences

A commonly used probe for Positron Emission Tomography (PET) scanning and a new probe developed by researchers at UCLA reveal different functions in diverse cells of the immune system, providing a non-invasive and much clearer picture of an immune response in action.

Released: 14-May-2010 1:45 PM EDT
Children with Epilepsy Say Their Quality of Life Is Better than Their Parents Think
University of California, Los Angeles (UCLA), Health Sciences

UCLA researchers found that children with epilepsy say their quality of life is comparable to that of their healthy siblings. The parents of these children, though, say just the opposite. They rate their children with epilepsy as having a substantially worse quality of life than their other, healthy children.

30-Apr-2010 7:00 PM EDT
Adult Survivors of Childhood Cancers Four Times More Likely to Develop Post-Traumatic Stress Disorder
University of California, Los Angeles (UCLA), Health Sciences

Young adult survivors of childhood cancers are four times more likely to develop Post-Traumatic Stress Disorder (PTSD) than their control group siblings, a Childhood Cancer Survivors Study has found.

Released: 29-Apr-2010 9:00 AM EDT
Study Finds High Rates of At-Risk Drinking Among Elderly Adults
University of California, Los Angeles (UCLA), Health Sciences

Research finds that more than a third of drinkers 60 years old and older consume amounts of alcohol that are excessive or that are potentially harmful in combination with certain diseases they may have or medications they may be taking.

Released: 19-Apr-2010 8:40 PM EDT
Obesity Gene, Carried by More than a Third of the U.S. Population, Leads to Brain Tissue Loss
University of California, Los Angeles (UCLA), Health Sciences

UCLA researchers have found that a variant of the fat mass and obesity associated (FTO) gene, found in more than a third of the world’s population and known to cause weight gain, is also associated with a loss of brain tissue.

Released: 13-Apr-2010 10:00 PM EDT
Health Fair Referrals Help Improve Patients' Blood Pressure
University of California, Los Angeles (UCLA), Health Sciences

Researchers researchers found that patients who received phone assistance in making doctors appointments had twice the improvement in systolic blood pressure of those assisted by a faith community nurse.

Released: 13-Apr-2010 12:00 PM EDT
Study Compares Bypass Surgery to Angioplasty
University of California, Los Angeles (UCLA), Health Sciences

A new UCLA study compares the safety and efficacy of heart bypass surgery to angioplasty with drug-eluting stents in patients with left main coronary artery disease, a diagnosis affecting thousands of individuals. Drug-eluting stents are treated with a medication that helps keep the artery from reclosing.

Released: 12-Apr-2010 4:40 PM EDT
Lockheed Martin Pledges $4 Million to Help UCLA Program That Aids Wounded Warriors
University of California, Los Angeles (UCLA), Health Sciences

The Lockheed Martin Corp. announced a pledge of $4 million to benefit the UCLA Health System's Operation Mend program, which provides reconstructive surgeries and other health care needs to U.S. military personnel wounded in Iraq and Afghanistan.

Released: 12-Apr-2010 4:30 PM EDT
UCLA's Semel Institute Awarded $15M to Establish New Integrative Phenotyping Center
University of California, Los Angeles (UCLA), Health Sciences

The Semel Institute for Neuroscience and Human Behavior at UCLA has been awarded $14.9 million in American Recovery and Reinvestment Act funds to establish a center dedicated to understanding the genetic and environmental factors in neuropsychiatric and behavioral disorders.

Released: 12-Apr-2010 4:25 PM EDT
Researchers Make First Direct Recording of Mirror Neurons in Human Brain
University of California, Los Angeles (UCLA), Health Sciences

UCLA researchers have, for the first time, made direct recordings of mirror neurons in the living human brain.

Released: 12-Apr-2010 4:20 PM EDT
Simple Test Can Detect Signs of Suicidal Thoughts in People Taking Antidepressants
University of California, Los Angeles (UCLA), Health Sciences

UCLA researchers have developed a non-invasive biomarker that may serve as a type of early warning system when antidepressants make a patient's condition worse.

Released: 1-Apr-2010 12:25 PM EDT
L.A. Marathon Cardiac Arrest Victim Doing Well After Induced Hypothermia Treatment at UCLA
University of California, Los Angeles (UCLA), Health Sciences

Jay Yim, 21-year-old student, collapsed at mile 18 of the LA Marathon in full cardiac arrest, and was saved by joint efforts of LAPD and UCLA doctors.

Released: 25-Mar-2010 8:00 PM EDT
Medical Conditions Putting Seniors at Risk of Medicare Donut Hole
University of California, Los Angeles (UCLA), Health Sciences

Among seniors, women and patients with diabetes and dementia are the most likely to fall into the Medicare Part D prescription drug plan "donut hole" — the gap occurring after beneficiaries reach their annual coverage limit and before catastrophic coverage kicks in.

Released: 16-Mar-2010 2:00 PM EDT
Novel 'Medical Home' Program for Pediatric Patients, Families Cuts ER Visits in Half
University of California, Los Angeles (UCLA), Health Sciences

In the first quantitative study to look at the benefits of utilizing the medical home concept in a resident-education outpatient clinic at a specialized children's hospital, UCLA researchers found that participation in the program at UCLA significantly reduced families' use of the emergency room.

Released: 2-Mar-2010 9:15 PM EST
Herceptin and Tykerb Effective Against a Subset of Gastric Cancers
University of California, Los Angeles (UCLA), Health Sciences

A combination of two targeted therapies already shown to be effective in breast cancer packs an effective one-two punch against a subset of gastric cancers that have a specific genetic mutation, a study at UCLA’s Jonsson Comprehensive Cancer Center has found.

Released: 26-Feb-2010 8:45 AM EST
OneWest Foundation Grant Helps Launch Project to Help Low-income Patients Obtain Medical Care Through UCLA, Venice Family Clinic
University of California, Los Angeles (UCLA), Health Sciences

Thanks to a generous three-year, $300,000 grant from the OneWest Foundation - matched by funds from the UCLA Health System - qualified Venice Family Clinic patients who need hospitalization or specialized medical care may now be helped by a pilot project launched by the foundation, the clinic and the UCLA Health System.

   
Released: 25-Feb-2010 4:15 PM EST
Stem Cell Therapy Removes Cell Receptor that Attracts HIV
University of California, Los Angeles (UCLA), Health Sciences

Researchers successfully removed CCR5 — a cell receptor to which HIV-1 binds for infection but which the human body does not need — from human cells. Individuals who naturally lack the CCR5 receptor have been found to be essentially resistant to HIV.

   
Released: 24-Feb-2010 3:45 PM EST
Study Finds Genetic Link Between Misery and Death
University of California, Los Angeles (UCLA), Health Sciences

UCLA researchers have discovered what they describe as a biochemical link between misery and death. In addition, they found a specific genetic variation in some individuals that seems to disconnect that link, rendering them more biologically resilient in the face of adversity.

Released: 24-Feb-2010 11:00 AM EST
Team Develops New Tool to Help Guide Pancreatic Cyst Treatment
University of California, Los Angeles (UCLA), Health Sciences

A UCLA–Veterans Affairs research team has developed an evaluation tool to help guide asymptomatic pancreatic cyst treatment. The tool takes into account overall health, age, cyst size, surgical risk and patients' views about quality of life.

Released: 22-Feb-2010 4:15 PM EST
UCLA Cardiothoracic Surgery Chief Elected Director-at-Large of the Society of Thoracic Surgeons
University of California, Los Angeles (UCLA), Health Sciences

UCLA's Dr. Richard J. Shemin was recently elected director-at-large of the Society of Thoracic Surgeons’ (STS) Board of Directors at the 46th Annual Meeting in Fort Lauderdale, Florida.

18-Feb-2010 8:45 AM EST
Study Reveals How Genes Interact with Environment to Cause Disease
University of California, Los Angeles (UCLA), Health Sciences

A UCLA study reveals how human genes interact with their environment to boost disease risk. The new findings shed light on why the search for specific gene variants linked to human diseases can only partly explain common disorders.

Released: 11-Feb-2010 8:00 AM EST
Predicting Prognosis and Treatment Response in Subset of Pancreatic Cancer Patients
University of California, Los Angeles (UCLA), Health Sciences

Specific chemical modifications to proteins called histones, which are found in the nucleus of cells and act as spools around which DNA is wound, can be used to predict prognosis and response to treatment in subsets patients with pancreatic cancer, a study by researchers at UCLA’s Jonsson Comprehensive Cancer Center has found.

Released: 1-Feb-2010 7:45 PM EST
Researchers Find 'Broad Spectrum' Antiviral
University of California, Los Angeles (UCLA), Health Sciences

Researchers have identified a "broad spectrum" antiviral that is effective against numerous viruses, including HIV-1, influenza A, filoviruses, poxviruses, and others. hey cause some of the world's deadliest diseases, such as AIDS and Ebola.

Released: 28-Jan-2010 8:30 PM EST
Non-invasive Testing, Earlier Surgery Can Stop Seizures in Tuberous Sclerosis Complex
University of California, Los Angeles (UCLA), Health Sciences

A study by researchers with UCLA's Pediatric Epilepsy Surgery Program has found that an alternative, non-invasive approach to pre-surgical testing, along with earlier consideration for surgery, is associated with the best seizure-free surgical outcome in patients with tuberous sclerosis complex.

Released: 28-Jan-2010 8:30 PM EST
Researchers Image Earliest Signs of Alzheimer’s Before Symptoms Appear
University of California, Los Angeles (UCLA), Health Sciences

Researchers at UCLA were able to predict a brain’s progression to Alzheimer’s long before the symptoms of AD can be seen, hopefully allowing for early intervention.

25-Jan-2010 8:05 PM EST
Researchers Perform Complete Genomic Sequencing on Brain Cancer Cell Line
University of California, Los Angeles (UCLA), Health Sciences

Researchers at UCLA’s Jonsson Comprehensive Cancer Center have performed the first complete genomic sequencing of a brain cancer cell line, a discovery that may lead to personalized treatments based on the unique biological signature of an individual’s cancer and a finding that may unveil new molecular targets for which more effective and less toxic drugs can be developed.

Released: 28-Jan-2010 1:15 PM EST
Improved Air Quality Linked to Fewer Pediatric Ear Infections
University of California, Los Angeles (UCLA), Health Sciences

A new study suggests that improvements in air quality over the past decade have resulted in fewer cases of ear infections in children.

Released: 22-Jan-2010 1:00 PM EST
Have a Heart Healthy Valentine’s Day: Gift, Food and Activity Ideas from UCLA Experts
University of California, Los Angeles (UCLA), Health Sciences

UCLA medical experts provide heart healthy gift, food and activity ideas for Valentine's Day.

15-Jan-2010 1:00 PM EST
Med Students Say Conventional Medicine Would Benefit by Integrating Alternative Therapies
University of California, Los Angeles (UCLA), Health Sciences

The largest national survey of its kind that measured medical students’ attitudes and beliefs about complementary and alternative medicine (CAM) found that three-quarters of them felt conventional Western medicine would benefit by integrating more CAM therapies and ideas.

Released: 17-Jan-2010 9:00 PM EST
Mail-Order Pharmacies Use Improves Patients' Medication Adherence
University of California, Los Angeles (UCLA), Health Sciences

Patients who ordered their medications by mail were more likely to take them as prescribed by their physicians than patients who obtained medications from a local pharmacy.

Released: 7-Jan-2010 8:00 PM EST
Volunteering May Prevent the Elderly from Becoming Frail
University of California, Los Angeles (UCLA), Health Sciences

Study suggests that participating in volunteer activities may prevent frailty in older adults.

Released: 5-Jan-2010 8:00 PM EST
Natural Compound Blocks Hepatitis C Infection
University of California, Los Angeles (UCLA), Health Sciences

Researchers have identified two cellular proteins that are important factors in hepatitis C virus infection, a finding that may result in the approval of new and less toxic treatments for the disease, which can lead to liver cancer and cirrhosis.

30-Dec-2009 4:00 PM EST
Half of Depressed Americans Go Untreated
University of California, Los Angeles (UCLA), Health Sciences

UCLA/Wayne State University researchers found that only 21 percent of Americans suffering from clinical depression receive medical care consistent with American Psychiatric Association guidelines. Half receive no treatment at all. The majority of treated patients, nearly 45 percent, received psychotherapy with no medication. Only 34 percent of patients were prescribed antidepressants.

30-Dec-2009 1:30 PM EST
It’s Never Too Late to Quit Smoking and Save Your Vision, Finds Study of AMD in Elderly Women
University of California, Los Angeles (UCLA), Health Sciences

Need a little extra incentive to kick the habit? Just in time for New Year’s resolutions, a UCLA study finds that even after age 80, smoking continues to increase one’s risk for age-related macular degeneration (AMD), the leading cause of blindness in Americans over 65.

21-Dec-2009 1:00 PM EST
Scientists Find Molecular Switch to Prevent Huntington's Disease in Mice
University of California, Los Angeles (UCLA), Health Sciences

UCLA scientists have identified a molecular switch that prevents Huntington's disease from developing in mice. Published in the Dec. 24 edition of the journal Neuron, the discovery suggests a new approach to treating the genetic disorder, which ultimately leads to death in as little as 10 years.

Released: 21-Dec-2009 8:00 PM EST
Enzyme Necessary for Healthy Immune System
University of California, Los Angeles (UCLA), Health Sciences

Mice without the deoxycytidine kinase (dCK) enzyme have defects in their adaptive immune system, producing very low levels of both T and B lymphocytes, the major players involved in immune response, according to a study by researchers with UCLA’s Jonsson Comprehensive Cancer Center.

Released: 16-Dec-2009 8:25 PM EST
Social Networks Help Hispanics Prepare for Disasters
University of California, Los Angeles (UCLA), Health Sciences

Informal social networks are more effective than mailers and "media blitzes" at encouraging Hispanics to prepare for disasters.

Released: 15-Dec-2009 10:20 PM EST
Marking Tissue-Specific Genes in Embryonic Stem Cells Crucial to Ensure Proper Function
University of California, Los Angeles (UCLA), Health Sciences

Tissue-specific genes, thought to be dormant or not marked for activation in embryonic stem cells, are indeed marked by transcription factors, with proper marking potentially crucial for the function of tissues derived from stem cells.

Released: 15-Dec-2009 9:00 AM EST
Targeting Brain Cancer Cell Metabolism May Provide New Treatment Option
University of California, Los Angeles (UCLA), Health Sciences

Inhibiting fatty acid synthesis in brain cancer cells may offer a new option to treat about 50 percent of deadly glioblastomas that are driven by amplified signaling of the epidermal growth factor receptor (EGFR), according to a first-of-its-kind study by researchers at UCLA’s Jonsson Comprehensive Cancer Center.

Released: 7-Dec-2009 8:40 PM EST
Stem Cells Can be Engineered to Kill HIV
University of California, Los Angeles (UCLA), Health Sciences

Researchers from the UCLA AIDS Institute and colleagues have for the first time demonstrated that human blood stem cells can be engineered into cells that can target and kill HIV-infected cells — a process that potentially could be used against a range of chronic viral diseases.

Released: 4-Dec-2009 3:20 PM EST
Most Runaway Teens Return Home with Help of Family Ties
University of California, Los Angeles (UCLA), Health Sciences

Unlike the stereotype of runaway teens becoming long-term homeless, more than two-thirds of newly homeless youth resolve their family differences and go home. The key is family intervention.

Released: 3-Dec-2009 3:05 PM EST
Are Stroke Survivors Taking Their Medicine?
University of California, Los Angeles (UCLA), Health Sciences

A new study to determine whether the use of antithrombotic medications among stroke survivors increased over a seven-year period found that in each of the years, approximately 20 percent of survivors were not taking these medications — a figure that did not decrease during the time period. The study also found that individuals who were younger, female or Hispanic were less likely to be taking antithrombotic agents.

Released: 25-Nov-2009 8:40 AM EST
Unacculturated Hispanics in US at Higher Risk for HIV
University of California, Los Angeles (UCLA), Health Sciences

Hispanics in the U.S. with low levels of acculturation — meaning adaptation to American culture — had fewer HIV tests and no hepatitis C tests, were more likely to test positive for HIV, and had low levels of access to health care.

Released: 19-Nov-2009 1:15 PM EST
Study Shows Brain's Ability to Reorganize
University of California, Los Angeles (UCLA), Health Sciences

Scientists from the UCLA Department of Neurology have confirmed that blindness causes structural changes in the brain, indicating that the brain may reorganize itself functionally in order to adapt to a loss in sensory input.

Released: 18-Nov-2009 12:55 PM EST
Researchers Create 'Fly Paper' to Capture Circulating Cancer Cells
University of California, Los Angeles (UCLA), Health Sciences

Just as fly paper captures insects, an innovative new device with nano-sized features developed by researchers at UCLA is able to grab cancer cells in the blood that have broken off from a tumor. These cells, known as circulating tumor cells, or CTCs, can provide critical information for examining and diagnosing cancer metastasis, determining patient prognosis, and monitoring the effectiveness of therapies.

Released: 16-Nov-2009 3:20 PM EST
Nanoparticles Found in Common Household Items Caused Genetic Damage in Mice
University of California, Los Angeles (UCLA), Health Sciences

Titanium dioxide (TiO2) nanoparticles, found in everything from cosmetics to sunscreen to paint to vitamins, caused systemic genetic damage in mice, according to a comprehensive study conducted by researchers at UCLA’s Jonsson Comprehensive Cancer Center.

10-Nov-2009 8:25 AM EST
People Entering Their 60s May Have More Disabilities Today than in Prior Generations
University of California, Los Angeles (UCLA), Health Sciences

Baby Boomers may well be entering their 60s suffering far more disabilities than their counterparts did in previous generations, The findings, may be due in part to changing American demographics.

9-Nov-2009 12:00 AM EST
Why Can't Chimps Speak? Study Links Evolution of Single Gene to Human Capacity for Language
University of California, Los Angeles (UCLA), Health Sciences

If humans are genetically related to chimps, why did our brains develop the innate ability for language and speech while theirs did not? Scientists suspect that part of the answer to the mystery lies in a gene called FOXP2. When mutated, FOXP2 can disrupt speech and language in humans. Now, a UCLA/Emory study reveals major differences between how the human and chimp versions of FOXP2 work, perhaps explaining why language is unique to humans.

Released: 10-Nov-2009 7:00 AM EST
FDA Approved Leukemia Drug Shows Promising Activity in Ovarian Cancer Cells
University of California, Los Angeles (UCLA), Health Sciences

The drug Sprycel, approved for use by the U.S. Food and Drug Administration in patients with chronic myeloid leukemia, significantly inhibited the growth and invasiveness of ovarian cancer cells and also promoted their death, a study by researchers with UCLA’s Jonsson Comprehensive Cancer Center found.



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