A UCLA study has discovered that chronic exposure during pregnancy to miniscule levels of carbon monoxide damages the cells of the fetal brain, resulting in permanent impairment. The journal BMC (BioMed Central) Neuroscience published the findings June 22 in its online edition.
Researchers here used a novel form of brain imaging to discover that white matter in the brains of adolescents at risk of developing schizophrenia does not develop at the same rate as healthy people. Further, the extent of these alterations can predict how badly patients will or will not deteriorate functionally over time.
UCLA and McGill University researchers have, for the first time, "photographed" a memory in the making.
Mattel Children's Hospital UCLA ranks among the nation's top pediatric hospitals, according to U.S. News News Media Group's 2009 edition of America's Best Children's Hospitals.
Researchers at UCLA's Jonsson Comprehensive Cancer Center, on a quest to find lung cancer stem cells, have developed a unique model to allow further investigation into the cells that many believe may be at the root of all lung cancers.
UCLA scientists discovered an enzyme called Idol that destroys the cell receptor for LDL cholesterol, permitting more 'bad' cholesterol to circulate in the blood. By blocking Idol's activity, the researchers triggered cells to make more receptor and absorb more cholesterol from the body. The finding could lead to a new drug taken in combination with statins, or for patients who cannot tolerate statins' side effects.
A long-term study by researchers at UCLA's Jonsson Comprehensive Cancer Center found that the three most common treatments for localized prostate cancer had significant impacts on patients' quality of life, a finding that could help guide doctors and patients in making treatment decisions.
Dr. Noah Federman, assistant professor of pediatric hematology/oncology and director of the Pediatric Bone and Soft Tissue Sarcoma Program at Mattel Children's Hospital UCLA, has been selected as the winner of the fourth annual Today's and Tomorrow's Children Fund Faculty Presentation Award.
The Pediatric Pain Program at Mattel Children's Hospital UCLA was honored with the Clinical Centers of Excellence in Pain Management Award by the American Pain Society (APS) at the organization's 28th Annual Scientific Conference in San Diego, CA on May 7.
The Brain Injury Research Center (BIRC) in the UCLA Department of Neurosurgery has been awarded a $4.2 million grant from the National Institutes of Health to research new ways to heal the brain after a traumatic brain injury, or TBI. Specifically, researchers will be looking at how to best feed the brain the nutrients it needs to optimize recovery.
If you had cancer and a genetic test could predict the risk of aggressive metastasis, would you want to know "“ even if no treatments existed to help you? An overwhelming majority of eye cancer patients would answer yes, according to a new UCLA study published in the June edition of the Journal of Genetic Counseling.
UCLA scientists have linked for the first time intestinal inflammation with systemic chromosome damage in mice, a finding that may lead to the early identification and treatment of human inflammatory disorders, some of which increase risk for several types of cancer.
Hyperkyphosis, or "dowager's hump" "” the exaggerated forward curvature of the upper spine seen commonly in elderly women "” may predict earlier death in women whether or not they have vertebral osteoporosis.
UCLA scientists have discovered a variant of a gene that may increase a child's risk of developing autism, particularly in boys.
Traumatic Brain Injury is the single most common cause of death and disability in children and adolescents, according to the Centers for Disease Control. Now, according to a new study by UCLA researchers, the effects of a blow to the head, whether it's mild or a concussion, can linger for years.
UCLA researchers report that certain regions in the brains of long-term meditators were larger than non-meditators. Specifically, meditators showed significantly larger volumes of the hippocampus and areas within the orbito-frontal cortex, the thalamus and the inferior temporal gyrus "” all regions known for regulating emotions.
Summer will soon arrive and UCLA emergency physicians would like to remind parents how to prevent drowning and water immersion injuries involving children. These unfortunate and heart-wrenching events most often occur in the summer months that are filled with water activities.
Women with vasomotor symptoms (VMS) "” which include hot flashes and night sweats "” had lower bone mineral density than those without VMS
The International Medical Graduate program is a unique program run through UCLA's Department of Family Medicine that assists medical school graduates from Latin America in passing their U.S. licensing exams. Kaiser Permanente has given the program a $2 million grant to expand
A drug widely used to treat Type 2 diabetes may have unintended effects on the pancreas that could lead to a form of low-grade pancreatitis in some patients and a greater risk of pancreatic cancer in long-term users. Sitagliptin, sold in pill form as Januvia, caused abnormalities in the pancreas of some test rats.
With cases of swine flu continuing to spread, the Centers for Disease Control and Prevention and the Homeland Security Department have declared a public health emergency, and the World Health Organization and governments around the globe are organizing to confront the potential crisis. UCLA has experts.
A new multicenter study involving UCLA and the RAND Corp. has found that perceived racial or ethnic discrimination is not an uncommon experience among fifth-grade students and that it may have a negative effect on their mental health.
UCLA researchers found that years of exposure to a combination of pesticides increased the risk of Parkinson's by 75 percent. Further, for people diagnosed with early on-set Parkinson's, earlier exposure had increased their risk for the disease by as much as four- to six-fold.
Oncologists often have to wait months before they can determine whether a treatment is working. Now, using a non-invasive method, researchers at UCLA's Jonsson Comprehensive Cancer Center have shown that they can determine after a single cycle of chemotherapy whether the toxic drugs are killing the cancer or not.
A special class designed at UCLA for teens with autism spectrum disorders a range of developmental disorders that consist of problems with communication and socialization helped the teens' overall social skills and interactions with their peers.
After 12 years of searching, UCLA scientists have tracked down the first known gene mutation responsible for a heartbreaking disorder that kills newborn babies. Published in the April 1 online edition of the American Journal of Human Genetics, their findings will allow for earlier testing of embryos at risk for the disease.
African Americans account for nearly 49 percent of newly diagnosed HIV/AIDS cases nationwide. About 500,000 African Americans are now living with HIV/AIDS. Yet there are very few African American HIV/AIDS researchers. A new study outlines a strategy to reverse this trend.
Dr. E. Richard Stiehm, distinguished professor of pediatrics at Mattel Children's Hospital UCLA, received the 2009 Special Recognition Award from the American Academy of Allergy, Asthma and Immunology (AAAAI) in Washington D.C. on March 14.
UCLA has added a new tool to its cancer-fighting arsenal, a state-of-the-art image-guided device that provides more accurate, concentrated doses of radiation, allowing patients to be treated in fewer visits and suffer from fewer side effects.
Insomnia patients have a dysregulation in energy balance that could explain why they gain weight over time. The findings highlight how diverse behaviors like sleep and eating are connected, and serves as another example of the importance of a good night's sleep for the body.
Researchers at UCLA's Jonsson Comprehensive Cancer Center have developed an assay that may be used to help identify new genes that can predict a predisposition to cancer.
African Americans have a shorter life expectancy than whites. A new study finds that for most types of cancer, the disparity in mortality is almost entirely due to the fact that African Americans are more likely to get cancer in the first place. Overall, African American men live 1.47 fewer years than white men, and African American women 0.91 fewer years than white women, due to all cancers combined.
A new type of brain-imaging scanner shows that intelligence is strongly influenced by the quality of the brain's axons that sends signals throughout the brain.
In a study of otherwise healthy, normal teens who self-reported various negative interpersonal interactions, UCLA researchers found that a greater frequency of such stress was associated with higher levels of an inflammatory marker called C-reactive protein, or CRP. CRP has been identified as an indicator for the later development of cardiovascular disease (CVD).
March is colorectal cancer awareness month. UCLA provides tips to lower the risk of colorectal cancer.
UCLA has launched a first-of-its-kind, patient-centered institute dedicated to developing leading-edge therapies for the treatment of kidney, bladder, testicular and prostate cancers.
UCLA researchers report that a naturally occurring compound found in broccoli and other cruciferous vegetables may help protect against respiratory inflammation that causes conditions like asthma, allergic rhinitis and chronic obstructive pulmonary disease.
The Rosalinde and Arthur Gilbert Foundation has pledged $1 million to The UCLA Foundation to fund an endowed chair in clinical pharmacology at the David Geffen School of Medicine at UCLA. Clinical pharmacology bridges the gap between laboratory science and the practice of medicine. Its primary aims are to promote safe and effective pharmaceutical drug use in patients and to optimize the medical benefits and minimize the potential risks of prescription drugs in treating diseases that affect mankind. The clinical pharmacology program at UCLA studies issues related to drug interactions, the individual's response to drugs and how different ethnicities metabolize drugs.
Stem cells scientists at UCLA showed for the first time that human induced pluripotent stem (iPS) cells can be differentiated into electrically active motor neurons, a discovery that may aid in studying and treating neurological disorders.
A new study finds that gene therapy can be developed as a safe and active technique to combat HIV. Researchers involved in this first-of-its-kind study found that cell-delivered gene transfer has the potential to be a once-only treatment that reduces viral load, preserves the immune system and avoids lifelong antiretroviral therapy.
Drinking at least three cups of green or black tea a day can reduce the risk of stroke by 21 percent, a new study has found. And the more you drink, the better your odds of staving off a stroke.
The Anthem Blue Cross Foundation has awarded Mattel Children's Hospital UCLA a $412,800 grant to launch the Fit for Residents program. The project will transform the future primary care workforce to be more effective practitioners in the prevention and management of pediatric obesity, and in turn, reduce type 2 diabetes and heart disease.
Patients who arrived at specific hospitals within an hour of experiencing stroke symptoms received a powerful clot-busting drug twice as often as those who arrived later in the approved time window for treatment.
UCLA scientists have tested a non-invasive approach that may one day allow doctors to evaluate a tumor's response to a drug before prescribing therapy, enabling physicians to quickly pinpoint the most effective treatment and personalize it to the patient's unique biochemistry. The Proceedings of the National Academy of Sciences publishes the UCLA findings in its Feb. 2 advance online edition.
Hospitals in states where Medicaid does not pay for routine male circumcision are only about half as likely to perform the procedure, and this disparity could lead to an increased risk of HIV infection among lower-income children later in life.
A bad economy can take its toll on the heart with increased stress, poor eating and forgoing healthful activities like going to the gym when money is tight. UCLA cardiologists suggest the following tips to help protect the heart during this time of financial uncertainty.
For the first time, UCLA researchers have reprogrammed human induced pluripotent stem (iPS) cells into the cells that eventually become eggs and sperm, possibly opening the door for new treatments for infertility using patient-specific cells.
Research has shown that certain marginalized groups fare worse than others in the aftermath of natural disasters, suffering disproportionate impoverishment, injuries and fatalities. Now a new study finds that they also experience greater terrorism-related fears and make more behavioral changes based on those fears.
It is well known that moderate drinking can have positive health benefits "” for instance, a couple of glasses of red wine a day can be good for the heart. But if you're a senior in good health, light to moderate consumption of alcohol may also help prevent the development of physical disability.
A new national study has shown that nearly 75 percent of patients hospitalized for a heart attack had cholesterol levels that would indicate they were not at high risk for a cardiovascular event, according to current national cholesterol guidelines.
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