With tens of thousands due to gather in Mexico City Aug. 3 for the 2008 International AIDS Conference, the journal AIDS has published a special supplement that provides concrete recommendations for addressing the complex social and economic issues that fuel HIV.
New UCLA research suggests that the treatment of early symptoms of memory loss may protect the brain and help people with mild age-related memory impairment. The finding also shows how PET offers researchers a tool for tracking the effectiveness of drugs prescribed to treat age-related cognitive decline.
UCLA researchers have confirmed the existence of biomarkers that may track the progression of AD, long before symptoms appear.
Immune cells end in protective caps, called telomeres, that are shorter in persons suffering chronic stress. Shortened telomeres are a sign of premature aging. A new UCLA study suggests that the stress hormone cortisol is the culprit behind telomeres' early aging and offers a potential drug target for protecting the immune system against the wear and tear of long-term stress.
Using an engineered common cold virus, UCLA researchers delivered a genetic payload to prostate cancer cells that allowed them, using Positron Emission Tomography (PET), to locate the diseased cells as they spread to the lymph nodes, the first place prostate cancer goes before invading other organs.
Two researchers from UCLA and the Veterans Affairs Greater Los Angeles Healthcare System have developed a design for an automated, wearable artificial kidney, or AWAK, that avoids the complications patients often suffer with traditional dialysis.
Vaginal microbicides currently in clinical trials may be the only weapon that will protect women against infection from HIV. Yet, under likely circumstances, these microbicides may be of more benefit to men than women.
UCLA scientists have solved the structure of a class of proteins known as sodium glucose co-transporters (SGLTs), which pump glucose into cells. The solution of the SGLT structure will accelerate development of new drugs designed to treat patients with diabetes and cancer. The journal Science publishes the findings.
A new program designed by UCLA and supported by the US Navy's Bureau of Medicine is reaching out to military families who are under severe stress due to a family member's multiple deployments to a war zone. Project FOCUS"”Families OverComing Under Stress"”is now being rolled out to nine military bases across the nation and in Okinawa, Japan.
The new state-of-the-art Mattel Children's Hospital UCLA opened its doors on June 29.
UCLA researchers discovered that an FDA-approved drug reverses mental retardation in mice with a genetic disease called tuberous sclerosis complex (TSC). Because half of TSC patients also suffer from autism, the findings offer a possible mechanism for addressing learning disorders due to autism.
Scientists at UCLA suggest that long-term grief activates neurons in the reward centers of the brain, possibly giving these memories addiction-like properties.
Practicing tai chi chih, the Westernized version of a 2,000-year-old Chinese martial art, promotes sleep quality in older adults with moderate sleep complaints.
Got memory problems? If you suffer from obstructive sleep apnea, your brain could be to blame. UCLA researchers have discovered that people with sleep apnea show tissue loss in brain centers that help store memory. Reported in the June 27 edition of the journal Neuroscience Letters, the findings emphasize the importance of early detection of the disorder, which afflicts an estimated 20 million Americans.
A blood substitute's effectiveness and safety was addressed in a large Phase III clinical trial by academic and industry researchers.
Researchers at UCLA's Jonsson Comprehensive Cancer Center have modified a common chemotherapy drug to create a new probe for Positron Emission Tomography (PET), an advance that will allow them to model and measure the immune system in action and monitor response to new therapies.
HIV-positive African American and Hispanic men who were sexually abused as children are particularly vulnerable to engaging in high-risk sex and experiencing depressive symptoms. Yet there are few intervention programs to help them. A new study finds that interventions that address their life experiences can contribute significantly toward preventing high-risk behavior and reducing depression rates.
UCLA/VA researchers have discovered the genetic cause of a type of childhood epilepsy called childhood absence epilepsy (CAE), which accounts for 10-12 percent of epilepsy cases in children under age 16. The finding may explain why CAE mysteriously disappears in adulthood. In addition, the study may provide insight into developing treatments and cures for CAE and other forms of epilepsy.
Tobacco smokers who eat three servings of fruits and vegetables per day and drink green or black tea may be protecting themselves from lung cancer, according to a first-of-its-kind study by UCLA cancer researchers.
UCLA researchers will use music as a tool to explore the ability of children with autism spectrum disorders to identify emotions in musical excerpts and facial expressions.
The UCLA Technology and Aging Conference will bring together academic and industry experts to highlight the latest medical and consumer technologies leading to longer, healthier lives. Panel discussions will explore the intersection of technology and aging in areas such as robotics, operating-room computer advances, diagnostics, health monitoring and consumer product development. Breakout sessions will address the latest developments in Alzheimer's and Parkinson's diseases, arthritis, nutrition, diabetes, joint replacement, audiology, memory and eye care.
Researchers found that low-dose antidepressant therapy can significantly improve the overall quality of life for adolescents suffering from irritable bowel syndrome, or IBS.
Stem cell researchers at UCLA were able to grow functioning cardiac cells using mouse skin cells that had been reprogrammed into cells with the same unlimited properties as embryonic stem cells.
Nearly two out of three patients have one or more precipitating factors that may contribute to hospital admissions nationwide for heart failure, according to a new UCLA study. Pneumonia, irregular heart beats and obstructed blood flow to the heart are the most frequent factors. The findings may help cardiologists better understand the factors that contribute to hospitalizations for heart failure and may help improve management of the disease.
Scientists with UCLA's Jonsson Cancer Center and the Department of Urology have showed that lowering intake of the type of fat common in a Western diet helps prevent prostate cancer in mice, the first finding of its kind in a mouse model that closely mimics human cancer, researchers said.
The National Institutes of Health has awarded four partner institutions $6 million to explore new ways to make kidney transplants more tolerable for children.
In the first external analysis of the California Department of Health Service's Medi-Cal Managed Care program, researchers from the UCLA Department of Family Medicine found widespread health care disparities based on ethnicity, race and language throughout the system. And African Americans are bearing the brunt of it.
Stem cell researchers from UCLA used a high resolution technique to examine the genome, or total DNA content, of a pair of human embryonic stem cell lines and found that while both lines could form neurons, the lines had differences in the numbers of certain genes that could control such things as individual traits and disease susceptibility.
Each Friday, Jewish patients at UCLA Medical Center receive a special gift from the hospital "” a clear plastic box filled with traditional items to help patients observe Shabbat.
The study findings show that sulforaphane, a chemical in broccoli, switches on a set of antioxidant genes and enzymes in specific immune cells, which then combat the injurious effects of molecules known as free radicals that can damage cells and lead to disease.
Solving a long-standing biological mystery, UCLA stem cell researchers have discovered that blood stem cells, the cells that later differentiate into all the cells in the blood supply, originate and are nurtured in the placenta.
The UCLA Department of Family Medicine, with support from the Robert Wood Johnson Foundation, has launched the Network for Multicultural Research on Health and Healthcare, a group that will study health care disparities affecting minorities with chronic diseases.
With colorectal cancer the second leading cause of cancer death, it's a great time to take a look at the health of your colon. UCLA offers 10 tips to help lower your risk of colorectal cancer. March is colorectal cancer awareness month.
The new Elder Economic Security Standard Index (Elder Index) for California, developed at UCLA, shows that the Federal Poverty Line (FPL), used to determine income eligibility for most public programs, covers less than half of the basic costs experienced by adults age 65 and older in the state.
Prostate cancers that are resistant to androgen deprivation therapy are more invasive and more likely to spread to other organs than androgen dependent prostate cancers, UCLA cancer researchers have found.
UCLA researchers show that the tiny brain of a fruit fly combines massive amounts of information from its sense of smell and vision, then transforms these sensory signals into stable and flexible flight behavior that leads them to a food source. Understanding the integration of these sensory cues could be relevant to developing smarter robotic drones.
Men with jobs that require them to be physically active may be getting benefits beyond salary and health insurance - they may be at a decreased risk of developing prostate cancer, according to a study at UCLA's Jonsson Cancer Center.
UCLA stem cell scientists have reprogrammed human skin cells into cells with the same unlimited properties as embryonic stem cells without using embryos or eggs.
Mattel Children's Hosptial UCLA offers new hope for young patients with pulmonary hypertension.
A new study shows that select patients age 65 and older can safely undergo lung transplantation and have acceptable outcomes.
Positron Emission Tomography (PET) was much more sensitive and more accurate than conventional imaging methods in detecting response to treatment in sarcoma patients, according to a UCLA study that is among the first to directly compare PET to CT scanning.
Researchers at UCLA's Jonsson Cancer Center have discovered biomarkers that predict which patients with advanced non-small cell lung cancer will respond to a combination treatment of the anti-inflammatory drug Celebrex and the growth factor receptor blocker Tarceva.
UCLA and University of North Carolina researchers have found that women with irritable bowel syndrome (IBS) who have experienced sexual and/or physical abuse may have a heightened brain response to pain that makes them more sensitive to abdominal discomfort.
A new study shows that only about half of children diagnosed with ADHD exhibit the cognitive defects commonly associated with the condition. Also, in populations where medication is rarely prescribed to treat ADHD, the prevalence and symptoms are roughly equivalent to populations in which medication is widely used.
Using nanotechnology, scientists from UCLA and Northwestern University have developed a localized and controlled drug delivery method that is invisible to the immune system, a discovery that could provide newer and more effective treatments for cancer and other diseases.
A new academic study led by UCLA revealed that the smallest particles from vehicle emissions may be the most damaging components of air pollution in triggering plaque build-up in the arteries that can lead to heart attack and stroke. The scientists also identified a way in which pollutant particles may promote hardening of the arteries "“ by inactivating the protective qualities of HDL cholesterol, known as the "good cholesterol."
With Valentine's Day just around the corner, it's a great time to take a look at the state of your heart.
UCLA researchers have found that a key protein in the body's dendritic cells can stop the virus that causes AIDS from "budding" "” part of the virus' life cycle that is crucial to its ability to replicate and infect other cells.
Measuring the response of single cells in humans, UCLA researchers have discovered that auditory neurons in our brains can discern the subtlest of sound frequencies, far superior to what almost all non-human animals, who presumably require such discrimination for survival, can discern.
UCLA scientists used language onset "“ the age when a child speaks his first word "“ as a tool for identifying a new gene linked to autism. The team also discovered that the gene is most active in brain regions involved with language and thought. Interestingly, evidence for the genetic link came from the DNA of families with autistic boys, not those with autistic girls.
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