UCLA scientists, along with collaborators from Purdue University, have demonstrated that HIV protease inhibitors "” crucial drugs for HIV treatment "” block a cellular enzyme important for generating the structural scaffolding for the cell nucleus. The findings may offer insight into the side effects of HIV protease inhibitors.
Researchers isolated bisdemethoxycurcumin, the active ingredient of curcuminoids "“ a natural substance found in turmeric root "“ that may help boost the immune system in clearing amyloid beta, a peptide that forms the plaques found in Alzheimer's disease.
The latest developments in in-vitro fertilization will be covered at this four-day conference.
In a new study, UCLA/VA researchers measured the effect of hepatitis B on patients' quality of life "” beyond just the physical symptoms of the disease "” and created a new tool to better assess patients' overall well-being, which may help clinicians guide treatment.
There are many effective, albeit expensive, intervention programs aimed at encouraging HIV-positive people to practice less risky behavior. But a new UCLA study has found that self-monitoring by these patients is not only an effective strategy but is inexpensive and easy to implement as well.
Providing autistic children with explicit instructions to pay more attention to facial expressions and tone of voice elicited an increased response in the medial prefrontal cortex, part of the brain's network for understanding the intentions of others. The findings may have implications for future therapeutic interventions.
New research suggests that a breakdown of the myelin that develops early in the formation of the brain may lead to the symptoms of Huntington's disease, a rare, inherited neurological disorder.
PG-13 films have lots of "happy violence," say UCLA researchers. Borrowing from the late communications theorist George Gerbner, happy violence is that which is "cool, swift and painless." PG-13 films don't consider the consequences of violent acts, such as injury, death and the shattered lives of the people involved.
June is Prostate Cancer Awareness Month, and with Father's Day approaching, it's a great time think about the ways men can keep their prostates healthy and be proactive about cancer prevention.
Ronald Reagan UCLA Medical Center, which will feature the most advanced medical technology in the world and 520 large, private rooms for patients, was officially dedicated today at a ceremony attended by former first lady Nancy Reagan, California Gov. Arnold Schwarzenegger, former Gov. Gray Davis, Los Angeles Mayor Antonio Villaraigosa, UCLA Acting Chancellor Norman Abrams, architect and UCLA Medal recipient C.C. Pei, and other dignitaries.
Researchers at the Institute for Stem Cell Biology and Medicine at UCLA were able to take normal tissue cells and reprogram them into cells with the same unlimited properties as embryonic stem cells, the cells that are able to give rise to every cell type found in the body.
Dr. E. Richard Stiehm, professor of pediatrics in the division of allergy, immunology and rheumatology at Mattel Children's Hospital UCLA, was presented with the 2007 Abbott Laboratories Award in Clinical and Diagnostic Immunology at the annual meeting of the American Society for Microbiology (ASM).
Many patients with chronic hepatitis B are deficient in their understanding of the lifelong disease and often do not comply with the drug regimens necessary to control it, according to a new UCLA survey that suggests improved patient involvement in disease management decisions could be the key to fixing this problem.
Summer has arrived and UCLA emergency physicians would like to remind parents how to prevent drownings and water-immersion injuries involving children.
A new UCLA imaging study reveals how inhaling straight oxygen can harm the brain. Published in the May 22 edition of Public Library of Science (PLoS) Medicine, the findings fly in the face of national guidelines for resuscitation and recommend a new approach adding carbon dioxide to the gas mix to preserve brain function in patients.
The UCLA Stroke Center recently received the American Stroke Association's Get With The Guidelines"“Stroke Initial Performance Achievement Award.
A pilot study at UCLA has found that a testosterone gel for men with MS reduced symptoms, slowed brain degeneration and increased muscle mass.
UCLA researchers have found that Parkinson's disease patients have severe damage to the same small group of neurons whose loss causes narcolepsy. The findings suggest a different clinical course of treatment for people suffering with Parkinson's that may ameliorate their sleep symptoms.
New research suggests that it is the breakdown of so-called late-stage myelin that promotes the buildup of toxic amyloid-beta fibrils that eventually deposit in the brain and become the plaques which have long been associated with Alzheimer's disease.
UCLA AIDS Institute researchers have discovered that when a crucial portion of a peptide structure in monkeys that defends against viruses, bacteria and other foreign invaders is reversed, the peptide actually encourages infection with HIV. The findings could pave the way for the use of such peptides in gene therapy using HIV-based vectors as the delivery method.
Dr. Martin F. Shapiro, professor of medicine and chief of the division of general internal medicine and health services research at the David Geffen School of Medicine at UCLA, has received the Herbert W. Nickens Award, recognizing his commitment to cultural diversity in medicine.
Dr. Ronald W. Busuttil, professor and executive chairman of the UCLA Department of Surgery, has received the American Surgical Association's Medallion for Scientific Achievement, joining a list that includes the nation's most distinguished surgeons.
Dr. Gerald D. Buckberg, distinguished professor of surgery in the division of cardiothoracic surgery at the David Geffen School of Medicine at UCLA, was awarded the 2007 Scientific Achievement Award by the American Association for Thoracic Surgery in Washington D.C. on May 8.
A simple blood test "” beyond standard lab tests "” taken at hospital admission strongly predicted in-hospital mortality risk for heart failure patients and may be useful in helping doctors decide which patients need higher-level monitoring and more intensive treatment.
A new study shows that more than half of children with an HIV-infected parent are not consistently in that parent's custody.
A recent UCLA study demonstrates that in autistic children, areas of the brain that play a role in processing facial expressions and evaluating emotions show little or no activity.
New imaging research at UCLA shows that impairments in autistic children's ability to imitate and empathize can be linked to dysfunction in the brain's mirror-neuron system.
Public health officials say a major concern is an outright flu pandemic, such as a human strain of avian flu. It's not a question of if such a health crisis will come but when. Are we prepared? In a word, say three UCLA researchers, no.
Dr. Hillel Laks, professor of cardiothoracic surgery at the David Geffen School of Medicine at UCLA, was honored with a distinguished UCLA Chancellor's Professorship.
While investigating the impact of Hurricane Katrina on New Orleans evacuees, a group of UCLA researchers stumbled across something they had not been looking for "” the deep level of distrust the largely minority victims felt toward public health authorities. This distrust likely played a role in residents' response to evacuation warnings and advice.
The researchers found that the Hurricane Katrina evacuees' strong family ties had a profound influence on factors affecting evacuation, including transportation decisions, access to shelter and how they perceived evacuation messages. These ties both facilitated and hindered their evacuation.
A rigorous, long-term study of quality of life in patients who underwent one of the three most common treatments for prostate cancer found that each affected men's lives in different ways. The findings provide invaluable information for men with prostate cancer who are facing vital treatment decisions.
The number of Latinos who graduated from dental schools, and hence able to acquire licenses to practice dentistry in California, fell by nearly 80 percent between 1982 and 1999 from 74 to 15 percent, even as the state's Latino population increased by 42.7 percent (7.7 million to 10 million).
April is Foot Health Awareness Month and UCLA podiatrists have provided tips for maintaining healthy feet.
Lactate, long thought to be a mere waste product, may be a key fuel for injured brains.
Neuroscientists at UCLA have shown that lithium, long the standard treatment for bipolar disorder, increases the amount of gray matter in the brains of patients with the illness.
UCLA is offering an intervention program for families and teens in Los Angeles County to stop teens from running away from home due to dissension between parent and child. It is an effort to reduce chronic adolescent homelessness and HIV-related risk behaviors by teaching teens and their parents the necessary skills to deal with unresolved conflict.
UCLA scientists have identified a new molecule that may help regulate the delivery of fats to cells for energy and storage. This could lead to a better understanding of how we utilize fats from the foods that we eat.
Dr. Theodore B. Moore has been selected as the winner of the second annual Today's and Tomorrow's Children's Fund Faculty Presentation Award.
Dr. Richard J. Shemin has been appointed professor and chief of cardiothoracic surgery at UCLA Medical Center, vice chairman of the UCLA Department of Surgery and co-director of the new Cardiovascular Center at UCLA.
This month a UCLA researcher begins a widespread clinical trial of the female sex hormone estriol, produced during pregnancy, which she's shown sharply reduces the symptoms of multiple sclerosis.
Tai chi chih, the Westernized version of the 2,000-year-old Chinese martial art characterized by slow movement and meditation, significantly boosts the immune systems of older adults against the virus that leads to the painful, blistery rash known as shingles, according to a new UCLA study.
Detection of precancerous changes (anal dysplasia) by anal cytology "” essentially an anal canal Pap smear "” is a relatively new procedure and one that has yet to enter standard practice. This UCLA study demonstrated that abnormal anal cytology was highly predictive of anal cell abnormalities that were subsequently confirmed by anal biopsy.
UCLA scientists have devised a novel way to correct abnormal gene splicing "“ a common mutation that often leads to disease. They created a custom mask that prevents the cell from seeing the genetic defects and restores splicing to the correct location in the gene.
Researchers have found that Viagra may help patients with idiopathic pulmonary fibrosis, an incurable disease characterized by progressive scarring in the lungs, which often leads to a lung transplant.
According to UCLA researchers, the current U.S. child health system is failing to produce the kind of health outcomes that it could and should because it is powered by outdated logic, outmoded organization, and inadequate and misaligned finance strategies.
Even as the AIDS epidemic in Los Angeles County has shifted largely to Hispanics, primary care practitioners serving this segment of the population often fail to offer either HIV testing or safer sex advice to their patients, according to a new UCLA AIDS Institute study.
UCLA researchers have uncovered new clues that may explain why Graves' disease (GD) attacks the muscle tissue behind the eyes, often causing them to bulge painfully from their sockets, as in the late actor Marty Feldman. The findings may deepen understanding of how the autoimmune disorder damages the body and offer a new target for treating the disfiguring disease.
With March being Colorectal Cancer Awareness Month, UCLA experts offer ten tips to lower risk of colorectal cancer and to help maintain a healthy colon. UCLA experts are also available for interviews.
UCLA scientists received seven of 72 seed grants awarded today by the state to fund stem cell research, the first money distributed for work on human embryonic stem cells since California voters approved Proposition 71 in November 2004. Seed grant funding totaled $45 million.
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