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Released: 1-Mar-2017 5:05 PM EST
Multicenter Study Finds No Benefit to Treating Mild Thyroid Dysfunction During Pregnancy
UT Southwestern Medical Center

A large national study suggests that treating pregnant women for mildly low thyroid function does not improve the IQs of their babies or reduce preterm births or other negative outcomes.

Released: 27-Feb-2017 3:05 PM EST
Inactivity, Excess Weight Linked to Hard-to-Treat Heart Failures
UT Southwestern Medical Center

Lack of exercise and excessive weight are strongly associated with a type of heart failure that has a particularly poor prognosis, UT Southwestern Medical Center researchers determined in an analysis of data from three large studies.

Released: 20-Feb-2017 3:05 PM EST
BRCA Gene Plus Breast Cancer History Leads to Preventive Strike Against Pancreatic Cancer
UT Southwestern Medical Center

More than three decades after surviving breast cancer, Susanne Calabrette faced a second scare. In June 2016, an MRI for an unrelated condition revealed she had pancreatic cysts, giving her a chance for a pre-emptive strike against this killer cancer.

Released: 20-Feb-2017 12:05 PM EST
Protein Once Thought Exclusive to Neurons Helps Aggressive Cancers Grow, Spread, and Defy Death
UT Southwestern Medical Center

How we think and fall in love are controlled by lightning-fast electrochemical signals across synapses, the dynamic spaces between nerve cells. Until now, nobody knew that cancer cells can repurpose tools of neuronal communication to fuel aggressive tumor growth and spread.

Released: 16-Feb-2017 2:05 PM EST
New Studies Unravel Mysteries of How PARP Enzymes Work
UT Southwestern Medical Center

A component of an enzyme family linked to DNA repair, stress responses, and cancer also plays a role in enhancing or inhibiting major cellular activities under physiological conditions, new research shows.

16-Feb-2017 5:00 AM EST
UT Southwestern Researchers Develop Potential Treatment for Fatal, Incurable Kidney Disease
UT Southwestern Medical Center

Researchers at UT Southwestern Medical Center, working with a California biotech firm, have developed a potential drug to treat polycystic kidney disease – an incurable genetic disease that often leads to end-stage kidney failure

Released: 13-Feb-2017 4:05 PM EST
Moderation Key to Days of Wine and Chocolate
UT Southwestern Medical Center

If wine and chocolate are on the menu for Valentine’s Day, you might be doing your heart a tiny little favor, but moderation remains key, says Dr. Joseph Hill, Chief of Cardiology at UT Southwestern Medical Center.

Released: 8-Feb-2017 1:05 PM EST
UT Southwestern Scientists Identify Mechanisms Behind Harmful Changes in the Gut’s Bacterial Balance During Inflammation
UT Southwestern Medical Center

A study led by UT Southwestern Medical Center researchers has uncovered key molecular pathways behind the disruption of the gut’s delicate balance of bacteria during episodes of inflammatory disease.

Released: 6-Feb-2017 1:05 PM EST
Researchers Identify Ion Channel Necessary for Hormone and Anti-Obesity Drug to Suppress Eating
UT Southwestern Medical Center

UT Southwestern Medical Center researchers have identified an ion channel required for brain cells to suppress eating behavior in response to the hormone leptin or to the anti-obesity drug lorcaserin.

   
Released: 3-Feb-2017 1:05 PM EST
Cancer Drug Could Double as a Weapon Against Heart Disease, Promoting Regeneration of Damaged Heart Tissue
UT Southwestern Medical Center

An anticancer agent in development promotes regeneration of damaged heart muscle – an unexpected research finding that may help prevent congestive heart failure in the future.

Released: 1-Feb-2017 2:05 PM EST
UT Southwestern Researchers Identify Gene That Protects Against Inflammatory Bowel Disease
UT Southwestern Medical Center

UT Southwestern Medical Center researchers have identified a gene that protects the gut from inflammatory bowel disease (IBD).

Released: 31-Jan-2017 12:05 PM EST
UT Southwestern Researchers Urge Use of Evidence-Based Medicine to Avoid Overtreatment of Type 2 Diabetes
UT Southwestern Medical Center

UT Southwestern Medical Center research supports an evidence-based medicine (EBM) approach that embraces individualized care to prevent overtreatment, specifically for patients with type 2 diabetes.

Released: 24-Jan-2017 12:05 PM EST
Researchers Discover Potential New Target for Treating Glioblastoma
UT Southwestern Medical Center

Scientists have found a way to inhibit the growth of glioblastoma, a type of brain cancer with low survival rates, by targeting a protein that drives growth of brain tumors, according to research from the Peter O’Donnell Jr. Brain Institute and Harold C. Simmons Comprehensive Cancer Center.

24-Jan-2017 12:00 PM EST
Researchers Discover BRCA1 Gene Is Key for Blood Forming Stem Cells
UT Southwestern Medical Center

Researchers at from the Harold C. Simmons Comprehensive Cancer Center have found that the BRCA1 gene is required for the survival of blood forming stem cells, which could explain why patients with BRCA1 mutations do not have an elevated risk for leukemia. The stem cells die before they have an opportunity to transform into a blood cancer.

Released: 23-Jan-2017 12:05 PM EST
Choreographing the MicroRNA-Target Dance
UT Southwestern Medical Center

Molecular biologists at UT Southwestern Medical Center have uncovered a new mechanism that choreographs a complex molecular dance by applying the latest in gene editing technology combined with a traditional method of making a microRNA target produce a fluorescent green protein.

Released: 18-Jan-2017 12:05 PM EST
UT Southwestern Researchers Identify Novel Mechanism That Protects Pancreas From Digestive Enzymes
UT Southwestern Medical Center

UT Southwestern Medical Center researchers have uncovered the mechanism by which the stress hormone FGF21 keeps digestive enzymes from damaging the pancreas.

Released: 17-Jan-2017 12:05 PM EST
UT Southwestern Researchers Find Likely Cause – and Potential Way to Prevent – Vision Deterioration in Space
UT Southwestern Medical Center

Vision deterioration in astronauts who spend a long time in space is likely due to the lack of a day-night cycle in intracranial pressure. But using a vacuum device to lower pressure for part of each day might prevent the problem, UT Southwestern Medical Center researchers said.

Released: 11-Jan-2017 5:05 PM EST
UT Southwestern Scientists Identify Protein Central to Immune Response Against Tuberculosis Bacteria
UT Southwestern Medical Center

UT Southwestern Medical Center researchers have identified a protein that is central to the immune system’s ability to recognize and destroy the bacterium responsible for the global tuberculosis (TB) epidemic.

Released: 11-Jan-2017 10:05 AM EST
Simmons Cancer Center Joins National Cancer Institute, CDC Calling for Increased HPV Vaccinations to Prevent Cancer
UT Southwestern Medical Center

More than a decade after the HPV vaccine was deemed both safe and effective by the FDA for preventing several types of cancer, the vaccine is still underused by those who could benefit.

Released: 3-Jan-2017 1:05 PM EST
Researchers Uncover Mechanism for Cancer-Killing Properties of Pepper Plant
UT Southwestern Medical Center

– UT Southwestern Medical Center scientists have uncovered the chemical process behind anti-cancer properties of a spicy Indian pepper plant called the long pepper, whose suspected medicinal properties date back thousands of years.



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