The review has collected studies concerning the anticancer potential of curcumin against the most widespread cancers and also describing the molecular mechanisms of action.
A collaborative study of researchers from Thomas Jefferson University, Sbarro Institute for Cancer Research and Molecular Medicine of Temple University, University of Siena, and from the Spanish Center for the Applied Medical Research (CIMA) of the University of Navarra have discovered a novel targetable axis in mesothelioma patients.
Toxic environmental agents, to which anyone is involuntarily exposed, represent non-negligible risk for human health and, therefore, environmental contamination has become a theme of primary importance worldwide.
Sbarro Health Research Organization founder and Director, Antonio Giordano, M.D., Ph.D., has been recognized with a career award "for the great contributions he has made and which he will continue to make to science, medicine and research.
Results suggest that the combined treatment can lower the effective chemotherapy dosage, reduce side effects, improve tumor cell apoptosis, and reduce tumor cell migration.
Xylella fastidiosa, subsp. pauca is a bacterial pathogen currently devastating the olive orchards in Southern Italy (Apulia). Due to the epidemic, local production of olive oil has dropped by 90%, olive mills are shut down, the regional economy is suffering, and an invaluable cultural asset is compromised.
The extract successfully restored the blood glucose levels, body weight, and normalized oxidative stress on renal function in a test group of Zucker diabetic fatty rats.
RB1 status has emerged not only as a key factor in cancer development and progression, but also as a crucial determinant of cell fate in response to various anticancer treatments
“Individualized therapies are strongly recommended and the treatment decision should be made collaboratively with a multidisciplinary team consisting of obstetricians, gynecologists, oncologists, pediatricians, and psychologists,” says researcher.
Inhibition of the cellular enzyme thymine DNA glycosylase (TDG) may be an effective treatment for melanoma, according to research published in the journal Oncogene in January. The paper, “Thymine DNA glycosylase as a novel target for melanoma,” describes how inhibition of TDG, known for its role in cell repair and proliferation, may be used to trigger cell death of cancerous melanoma cells and halt tumor growth.
A synthetic DNA structure was used as bait to capture nuclear proteins, revealing previously unknown role of HNRNPD in the cellular response to DNA damage.
Researchers have successfully identified two genetic markers for potentially effective treatment of Mesothelioma, an orphan disease most commonly associated with asbestos exposure, and for which few treatments exist.
This week, SHRO partners with the Italian Movie Award International Film Festival to support Italian-American work in cinema, particularly in recognition for accomplishments with the use of Virtual Reality (VR) in applications in medicine