Understanding Neurodegenerative Disease Such as Alzheimer’s and ALS by Examining the Overlap of microRNAs, Oxidative Stress, and Mitochondria Dysfunction

These aspects may have important implications for the design of new drugs and therapeutic interventions for these progressive and incurable diseases.
26-Aug-2020 2:10 PM EDT Add to Favorites

International Mesothelioma Researcher Recognized for Her Work with the National Cancer Institution of Naples and Sbarro Health Research Organization

Held in Locri, Italy on Saturday, August 8 in the enchanting Riviera dei Gelsomini, the Women of Talent Award ceremony recognized the achievements of Francesca Pentimalli, PhD, a frequent collaborator on research with the Sbarro Health Research...
14-Aug-2020 1:10 PM EDT Add to Favorites

Key Immune System Genes Identified to Explain High COVID Deaths and Spread in Northern Italy Versus Fewer Cases and Deaths in the South

Not long after the Coronavirus disease (Covid-19) outbreak in China, Italy was hard-hit by the infection and rapidly became one of the countries with the highest mortality rate.
23-Jul-2020 8:05 AM EDT Add to Favorites

Despite Promising Lab Results, Most Precision Medicine Therapies for Mesothelioma Fail in the Clinical Setting

Malignant mesothelioma (MM) is a lethal cancer mainly caused by exposure to asbestos, for which, unfortunately, no current treatment has proven effective, despite the identification of several promising therapeutic targets over the years.
20-Jul-2020 11:25 AM EDT Add to Favorites

Monoclonal Antibody Restores T-Cell Ability to Kill Cancer

A new class of anticancer agents can restore the ability of cytotoxic T lymphocytes (CTLs) to infiltrate the tumor and kill target cells in patients with metastatic non-small cell lung cancer (mNSCLC).
23-Jun-2020 10:55 AM EDT Add to Favorites

Targeting Receptor EphA2 Reduces Bladder Cancer Tumor Growth and Increases Chemotherapy Effectiveness

An international team of investigators has recently discovered that the receptor tyrosine-kinase EphA2 activated by the growth factor progranulin is a tumorigenic driver of bladder cancer progression.
8-Jun-2020 2:05 PM EDT Add to Favorites

Genetics May Explain High COVID-19 Mortality in Italy, Inform Global Pandemic Response

Researchers predict the Human Leukocyte Antigen (HLA) gene has a key role in shaping immune response to COVID.
29-May-2020 2:40 PM EDT Add to Favorites

Researchers Silence PRMT5 Gene to Slow Mesothelioma Using Precision Medicine

Silencing of the protein coding gene PRMT5 has possible therapeutic potential for treating Mesothelioma (MM), according to a recent in vitro study published in the Journal of Cellular and Molecular Medicine.
1-May-2020 11:50 AM EDT Add to Favorites

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