Monoclonal Antibody Restores T-Cell Ability to Kill Cancer

A new class of anticancer agents can restore the ability of cytotoxic T lymphocytes (CTLs) to infiltrate the tumor and kill target cells in patients with metastatic non-small cell lung cancer (mNSCLC).
23-Jun-2020 10:55 AM EDT Add to Favorites

Targeting Receptor EphA2 Reduces Bladder Cancer Tumor Growth and Increases Chemotherapy Effectiveness

An international team of investigators has recently discovered that the receptor tyrosine-kinase EphA2 activated by the growth factor progranulin is a tumorigenic driver of bladder cancer progression.
8-Jun-2020 2:05 PM EDT Add to Favorites

Genetics May Explain High COVID-19 Mortality in Italy, Inform Global Pandemic Response

Researchers predict the Human Leukocyte Antigen (HLA) gene has a key role in shaping immune response to COVID.
29-May-2020 2:40 PM EDT Add to Favorites

Researchers Silence PRMT5 Gene to Slow Mesothelioma Using Precision Medicine

Silencing of the protein coding gene PRMT5 has possible therapeutic potential for treating Mesothelioma (MM), according to a recent in vitro study published in the Journal of Cellular and Molecular Medicine.
1-May-2020 11:50 AM EDT Add to Favorites

Considerations about current evolution of SARS-nCOV-2 epidemic in Italy

In Italy, a COVID-19 epidemic is raging. This analysis, which might be useful also to forecast the next epidemic trends in the U.S., is briefly recapitulated in the following document.
12-Mar-2020 10:15 AM EDT Add to Favorites

Understanding COVID-19 Origins First Step to Treating Cases, Stopping Spread

“The new virus originating from Wuhan is the third coronavirus that has made the ‘jump’ from animals to humans,” explains Enrico Bucci, Ph.D., professor and research scientist at the Sbarro Health Research Organization (SHRO), at Temple...
9-Mar-2020 8:55 AM EDT Add to Favorites

Link Found Between Bladder Cancer and Collagen Receptor, Revealing Possible Treatment Target

A team of investigators has recently discovered that the collagen receptor DDR1 functionally interacts with the insulin-like growth factor system in regulating bladder cancer.
7-Feb-2020 8:45 AM EST Add to Favorites

Lower Survival in Patients with High BMI and HER2+ Metastatic Breast Cancer Treated with Pertuzumab and Trastuzumab

An international team of researchers found that high BMI correlates to lower survival in patients with HER2+ metastatic breast cancer, even among patients showing initial positive response to new anti-HER2 agents pertuzumab and trastuzumab.
31-Jan-2020 9:00 AM EST Add to Favorites

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