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Released: 27-Jan-2014 9:30 AM EST
Health Care Costs Grow with Body Mass
Duke Health

Researchers at Duke Medicine report that health care costs increase in parallel with body mass measurements, even beginning at a recommended healthy weight. Pharmacy and medical costs may even double for obese people compared with those at a healthy weight, according to a recent study published in the journal Obesity.

Released: 23-Jan-2014 4:00 PM EST
Duke and University of Colorado Awarded $10 Million for Ongoing Work in Palliative Care
Duke Health

Duke University and the University of Colorado schools of medicine have received a $10 million grant from the National Institute for Nursing Research (NINR), part of the National Institutes of Health, to continue the development of the Palliative Care Research Cooperative Group (PCRC) over the next five years.

22-Jan-2014 12:00 PM EST
Long-Term Spinal Cord Stimulation Stalls Symptoms of Parkinson’s-like Disease
Duke Health

Researchers at Duke Medicine have shown that continuing spinal cord stimulation appears to produce improvements in symptoms of Parkinson’s disease, and may protect critical neurons from injury or deterioration.

9-Jan-2014 1:00 PM EST
Chemical Signaling Simulates Exercise in Cartilage Cells
Duke Health

Cartilage is notoriously difficult to repair or grow, but researchers at Duke Medicine have taken a step toward understanding how to regenerate the connective tissue. By adding a chemical to cartilage cells, the chemical signals spurred new cartilage growth, mimicking the effects of physical activity.

3-Jan-2014 3:00 PM EST
Bacteria Linked to Water Breaking Prematurely During Pregnancy
Duke Health

A high presence of bacteria at the site where fetal membranes rupture may be the key to understanding why some pregnant women experience their "water breaking" prematurely, researchers at Duke Medicine report.

26-Dec-2013 11:45 AM EST
Conversations on Sex Lacking Between Doctors and Teens
Duke Health

Doctors are missing a prime opportunity to share information about sex with their teenage patients by failing to broach the subject during checkups, according to researchers at Duke Medicine.

12-Dec-2013 2:15 PM EST
Stress Reaction Gene Linked to Death, Heart Attacks
Duke Health

A genetic trait known to make some people especially sensitive to stress also appears to be responsible for a 38 percent increased risk of heart attack or death in patients with heart disease, scientists at Duke Medicine report.

Released: 16-Dec-2013 10:25 AM EST
Health Care Costs Steadily Increase With Body Mass
Duke Health

Researchers at Duke Medicine are giving people another reason to lose weight in the new year: obesity-related illnesses are expensive. According to a study published in the journal Obesity, health care costs increase in parallel with body mass measurements, even beginning at a recommended healthy weight.

9-Dec-2013 9:05 AM EST
Salmonella Jams Signals From Bacteria-Fighting Mast Cells
Duke Health

A protein in Salmonella inactivates mast cells -- critical players in the body’s fight against bacteria and other pathogens -- rendering them unable to protect against bacterial spread in the body, according to researchers at Duke Medicine and Duke-National University of Singapore (Duke-NUS).

Released: 9-Dec-2013 5:00 PM EST
Duke Receives Grant to Fund Development of Potential HIV Vaccine
Duke Health

Duke University has received a grant of up to $2.9 million from the Bill & Melinda Gates Foundation to produce an HIV vaccine candidate that will be tested in humans.

Released: 5-Dec-2013 11:00 AM EST
New Children's Center Studies Association Between ADHD and Secondhand Smoke
Duke Health

Duke Medicine has established a new research program to investigate the relationship between exposure to environmental tobacco smoke during pregnancy and childhood and attention deficit hyperactivity disorder (ADHD) in children.

Released: 29-Nov-2013 10:00 AM EST
High Cholesterol Fuels the Growth and Spread of Breast Cancer
Duke Health

A byproduct of cholesterol functions like the hormone estrogen to fuel the growth and spread of the most common types of breast cancers, researchers at the Duke Cancer Institute report.

Released: 21-Nov-2013 8:00 AM EST
Rotator Cuff Surgery Saves Society Money
Duke Health

Surgery to repair torn rotator cuffs improves patients’ quality of life and can allow them to get back to work quickly, resulting in societal savings for patients 61 years and younger, according to a new analysis led by Duke Medicine.

Released: 20-Nov-2013 3:40 PM EST
Early Data Show Potential for Investigational Bioengineered Vessel as Dialysis Graft
Duke Health

An investigational, man-made blood vessel used in vascular grafts for kidney dialysis patients may potentially show encouraging early results among study patients in Poland, according to preliminary data reported Wednesday by a researcher at Duke Medicine.

Released: 19-Nov-2013 4:00 PM EST
Unhealthiest Stroke Patients Are Less Likely to Get Optimal Care
Duke Health

Among thousands of hospital patients treated for a “mini stroke,” those who were at highest risk for suffering a full-blown ischemic attack were less likely to received optimal care, according to a study led by researchers at Duke Medicine.

19-Nov-2013 9:45 AM EST
Oral Drug May Improve Survival in Men with Metastatic Prostate Cancer
Duke Health

An investigational prostate cancer treatment slows the disease’s progression and may increase survival, especially among men whose cancer has spread to the bones, according an analysis led by the Duke Cancer Institute.

14-Nov-2013 4:00 PM EST
Rural and Southern Regions Lack Annual Training in CPR
Duke Health

Annual rates of CPR training in the United States are low and vary widely across the country, but the communities most in need of training are the least likely to be trained, according to a new study from the Duke Clinical Research Institute.

Released: 18-Nov-2013 2:00 PM EST
Staying on Medication May Not Translate to Avoiding Readmission
Duke Health

A targeted effort to help high-risk heart failure patients stay on their medications did improve adherence to drug regimens, but had surprisingly little effect lowering hospital readmission rates, according to a study at Duke Medicine.

Released: 6-Nov-2013 2:00 PM EST
Monkeys Use Minds to Move Two Virtual Arms
Duke Health

In a study led by Duke researchers, monkeys have learned to control the movement of both arms on an avatar using just their brain activity.

Released: 29-Oct-2013 3:00 PM EDT
Women Benefit From Less-Used Wrist Access Site for Angioplasty
Duke Health

For women who are at high risk of blood loss, using an artery in the wrist may be better than the groin for routing a stent to the heart during coronary angioplasty, according to researchers at Duke Medicine.

22-Oct-2013 9:30 PM EDT
HPV Strains Affecting African-American Women Differ from Vaccines
Duke Health

Two subtypes of human papillomavirus (HPV) prevented by vaccines are half as likely to be found in African-American women as in white women with precancerous cervical lesions, according to researchers at Duke Medicine.

Released: 22-Oct-2013 3:00 PM EDT
New Artificial Protein Mimics A Part Of The HIV Outer Coat
Duke Health

A team of scientists at Duke Medicine and Memorial Sloan-Kettering Cancer Center has created an artificial protein coupled with a sugar molecule that mimics a key site on the outer coat of HIV where antibodies can bind to neutralize a wide variety of HIV strains.

16-Oct-2013 3:15 PM EDT
Breast Milk Protein May Be Key to Protecting Babies From HIV Infection
Duke Health

A substance in breast milk that neutralizes HIV and may protect babies from acquiring HIV from their infected mothers has been identified for the first time by researchers at Duke Medicine.

Released: 18-Oct-2013 12:00 PM EDT
New Prognostic Tool Predicts Survival in Advanced Prostate Cancer
Duke Health

Researchers at the Duke Cancer Institute have developed a tool for doctors to forecast the potential survival of individual patients, enabling faster, more accurate information on whether to try additional rounds of treatment or seek clinical trials.

10-Oct-2013 4:00 PM EDT
Rare Gene Mutation Sheds Light on Protein’s Role in Brain Development
Duke Health

Though worlds apart, four unrelated families have been united in a medical mystery over the source of a rare inherited disorder that results in their children being born with abnormal brain growth and severe functional impairments.

Released: 16-Oct-2013 9:40 AM EDT
Duke University School of Nursing Launches HIV/AIDS Nurse Practitioner Specialty Concentration
Duke Health

Duke University School of Nursing is currently accepting applications for its new HIV/AIDS specialty concentration within the Primary Care Nurse Practitioner major for the fall 2014 semester.

Released: 30-Sep-2013 3:00 PM EDT
New Insights into DNA Repair Process May Spur Better Cancer Therapies
Duke Health

By detailing a process required for repairing DNA breakage, scientists at the Duke Cancer Institute have gained a better understanding of how cells deal with the barrage of damage that can contribute to cancer and other diseases.

Released: 26-Sep-2013 11:00 AM EDT
Duke Medicine Selected as New Site for Competitive Vaccine and Treatment Research Program
Duke Health

Duke Medicine has been named a Vaccine and Treatment Evaluation Unit (VTEU) by the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, to evaluate vaccines, treatments and diagnostics to protect people from infectious diseases, including emerging public health needs.

Released: 18-Sep-2013 2:00 PM EDT
Genomic Test Accurately Sorts Viral vs. Bacterial Infections
Duke Health

A blood test developed by researchers at Duke Medicine showed more than 90-percent accuracy in distinguishing between viral and bacterial infections when tested in people with respiratory illnesses.

Released: 29-Aug-2013 1:00 PM EDT
September Summit To Launch Duke’s New Institute for Health Innovation
Duke Health

On Sept. 8 and 9, Duke University and Duke Medicine will launch the Duke Institute for Health Innovation (DIHI) and host an inaugural “Summit on Transformative Innovation in Health Care.”

Released: 27-Aug-2013 4:00 PM EDT
Three Subtypes of Gastric Cancer Suggest Different Treatment Approaches
Duke Health

Stomach cancer, one of the leading causes of cancer death worldwide, actually falls into three broad subtypes that respond differently to currently available therapies, according to researchers at Duke-NUS Graduate Medical School Singapore.

23-Aug-2013 3:00 PM EDT
Touch and Movement Neurons Shape the Brain’s Internal Image of the Body
Duke Health

The brain’s tactile and motor neurons, which perceive touch and control movement, may also respond to visual cues, according to researchers at Duke Medicine.

Released: 16-Aug-2013 12:30 PM EDT
Coffee and Tea May Contribute to a Healthy Liver
Duke-NUS Graduate Medical School Singapore

An international team of researchers led by Duke-NUS Graduate Medical School (Duke-NUS) and the Duke University School of Medicine suggest that increased caffeine intake may reduce fatty liver in people with non-alcoholic fatty liver disease (NAFLD).

Released: 16-Aug-2013 9:00 AM EDT
Drug Dosing for Older Heart Patients Should Differ
Duke Health

Older heart patients present unique challenges for determining the optimal dosages of medications, so a new study from researchers at Duke Medicine offers some rare clarity about the use of drugs that are used to treat patients with heart attacks.

8-Aug-2013 1:45 PM EDT
Inducing and Augmenting Labor May Be Associated with Increased Risk of Autism
Duke Health

Pregnant women whose labors are induced or augmented may have an increased risk of bearing children with autism, especially if the baby is male, according to a large, retrospective analysis by researchers at Duke Medicine and the University of Michigan.

8-Aug-2013 12:00 PM EDT
Newly Identified Genetic Factors Drive Severe Childhood Epilepsies
Duke Health

Researchers have identified two new genes and implicated 25 distinct mutations in serious forms of epilepsy, suggesting a new direction for developing tailored treatments of the neurological disorders. The findings by an international research collaboration, which includes investigators from Duke Medicine, appear Aug. 11 in the journal Nature.

Released: 1-Aug-2013 8:30 AM EDT
Study Reveals Target for Drug Development for Chronic Jaw Pain Disorder
Duke Health

In a study in mice, researchers at Duke Medicine identified a protein that is critical to temporomandibular joint disorder pain, and could be a promising target for developing treatments for the disorder.

24-Jul-2013 3:25 PM EDT
Requiring Some Patients to Get Mental Health Treatment Saves Money
Duke Health

Mandating outpatient treatment for certain people with severe mental illness, while controversial, results in substantial cost savings by cutting hospitalizations and increasing outpatient care, according to a financial analysis led by researchers at Duke Medicine.

26-Jul-2013 11:00 AM EDT
Childhood Economic Status Affects Substance Use Among Young Adults
Duke Health

Children who grow up in poverty are more likely than wealthier children to smoke cigarettes, but they are less likely to binge drink and are no more prone to use marijuana, according to researchers at Duke Medicine.

Released: 18-Jul-2013 9:00 AM EDT
Biochemical Mapping Helps Explain Who Will Respond to Antidepressants
Duke Health

Duke Medicine researchers have identified biochemical changes in people taking antidepressants – but only in those whose depression improves. These changes occur in a neurotransmitter pathway that is connected to the pineal gland, the part of the endocrine system that controls the sleep cycle, suggesting an added link between sleep, depression and treatment outcomes.

1-Jul-2013 11:00 AM EDT
Biomarker Predicts Heart Attack Risk Based on Response to Aspirin Therapy
Duke Health

Aspirin has been widely used for more than 50 years as a common, inexpensive blood thinner for patients with heart disease and stroke, but doctors have little understanding of how it works and why some people benefit and others don’t.

13-Jun-2013 4:00 PM EDT
Animal Study Shows Promising Path to Prevent Epilepsy
Duke Health

Duke Medicine researchers have identified a receptor in the nervous system that may be key to preventing epilepsy following a prolonged period of seizures. Their findings from studies in mice, published online in the journal Neuron on June 20, 2013, provide a molecular target for developing drugs to prevent the onset of epilepsy, not just manage the disease’s symptoms.

Released: 18-Jun-2013 10:00 AM EDT
Parenting and Home Environment Influence Children’s Exercise and Eating Habits
Duke Health

Kids whose moms encourage them to exercise and eat well, and model those healthy behaviors themselves, are more likely to be active and healthy eaters, according to researchers at Duke Medicine. Their findings, published online in the International Journal of Obesity on June 18, 2013, remind parents that they are role models for their children, and underscore the importance of parental policies promoting physical activity and healthy eating.

Released: 15-Jun-2013 2:00 PM EDT
Osteoporosis Drug Stops Growth of Breast Cancer Cells, Even in Resistant Tumors
Duke Health

A drug approved in Europe to treat osteoporosis has now been shown to stop the growth of breast cancer cells, even in cancers that have become resistant to current targeted therapies, according to a Duke Cancer Institute study.

Released: 6-Jun-2013 3:40 PM EDT
Re-Analysis of Diabetes Drug Finds No Higher Heart Attack Risk
Duke Health

A re-analysis of the data from a pivotal study of rosiglitazone found no increased risk of cardiovascular events associated with the controversial diabetes drug, according to researchers at the Duke Clinical Research Institute (DCRI).

Released: 6-Jun-2013 9:35 AM EDT
Surgeons at Duke University Hospital Implant Bioengineered Vein
Duke Health

In a first-of-its-kind operation in the United States, a team of doctors at Duke University Hospital helped create a bioengineered blood vessel and implanted it into the arm of a patient with end-stage kidney disease. The procedure, the first U.S. clinical trial to test the safety and effectiveness of the bioengineered blood vessel, is a milestone in the field of tissue engineering. The new vein is an off-the-shelf, human cell-based product with no biological properties that would cause organ rejection.

Released: 3-Jun-2013 10:00 AM EDT
Duke to Co-Lead NIH Research Network on Antibacterial Resistance
Duke Health

Investigators at Duke Medicine and UCSF have been selected by NIAID to oversee a nationwide research program on antibacterial resistance. Duke has been awarded $2 million in initial funding to launch the network; total funding for the award will reach at least $62 million through 2019.

16-May-2013 3:50 PM EDT
Antidepressant Reduces Stress-Induced Heart Condition
Duke Health

A drug commonly used to treat depression and anxiety may improve a stress-related heart condition in people with stable coronary heart disease, according to researchers at Duke Medicine.

Released: 21-May-2013 12:40 PM EDT
Poliovirus Vaccine Trial Shows Early Promise for Recurrent Glioblastoma
Duke Health

An attack on glioblastoma brain tumor cells that uses a modified poliovirus is showing encouraging results in an early study to establish the proper dose level, researchers at Duke Cancer Institute report.



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