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UC San Diego was awarded five COVID-19 Rapid Acceleration of Diagnostics (RADx) projects by the National Institutes of Health totaling nearly $33 million, which will fund efforts that range from managing a large data center to expanding testing in disadvantaged communities.

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UC San Diego School of Medicine researchers are using stem cell-derived organoids to study how SARS-CoV-2 interacts with various organ systems. Their findings may help explain the wide variety in COVID-19 symptoms and aid the search for therapies.

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Research from Herbert Wertheim School of Public Health and Human Longevity Science at UC San Diego suggests that light-intensity physical activity, including shopping or a casual walk, may protect against mobility disability in older women.

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Scientists at University of California San Diego School of Medicine validated a more inclusive and comprehensive genetic tool, known as a polygenic hazard score (PHS), for predicting age of onset of aggressive prostate cancer.

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Researchers at UC San Diego School of Medicine use bacteriotherapy to improve symptoms of atopic dermatitis.

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UC San Diego researchers have launched a first-in-human Phase I clinical trial to assess the safety and efficacy of a gene therapy to deliver a key protein into the brains of persons with Alzheimer’s disease or Mild Cognitive Impairment, a condition that often precedes full-blown dementia.

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Researchers at University of California San Diego School of Medicine identified new therapeutic targets for gastrointestinal stromal tumors (GISTs) that could lead to new treatment options for patients.

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UC San Diego researchers report that individual immune response to SARS-CoV-2 may be limited by a set of variable genes that code for cell surface proteins essential for the adaptive immune system. The finding may help explain why COVID-19 immunity varies by individual.

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The Psychedelics and Health Research Initiative at UC San Diego has received a $1.3 million grant from the Steven & Alexandra Cohen Foundation to fund a clinical trial investigating the therapeutic potential of psilocybin in treating phantom limb pain.

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UC San Diego clinical trial suggests ivabradine may be effective in treating postural orthostatic tachycardia syndrome, a potential COVID-19 long-hauler symptom.

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In a Q&A, UC San Diego Health cardiologist describes how COVID-19 is a as a “stress test” for the body, which could explain why individuals with underlying heart conditions are more at risk for severe COVID-19 infections.

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UC San Diego researchers discovered a single gene alteration that may help explain cognitive differences between modern humans and our predecessor, and used that information to develop Neanderthal-like brain organoids in the lab.

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In an effort to help schools reduce the risk of COVID-19 outbreaks as they resume in-person instruction, UC San Diego and the County of San Diego are testing the Safer at School Early Alert system to detect SARS-CoV-2 at schools and child care centers.

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UC San Diego researchers find that an optical tool already embedded in many smartphones can accurately diagnose blood-oxygen levels and help monitor respiratory disease in patients, particularly when they are quarantined at home.

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UC San Diego researchers report that climate change is a chronic mental health stressor, and promotes a variety of mental health problems. The 2018 Camp Fire is a case study.

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A new study by researchers at University of California San Diego School of Medicine found delayed time between abnormal stool-based screening and subsequent colonoscopy was associated with an increased risk of a cancer diagnosis and death from colorectal cancer.

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After analyzing the genomes of more 250,000 military veterans, researchers have identified 18 specific, fixed positions on chromosomes that appear associated with post-traumatic stress disorder. The findings may point to new therapeutic drug targets.

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Viral infections and space travel similarly trigger inflammation and the enzymes APOBEC3C and ADAR1; UC San Diego researchers are developing ways to inhibit them as a means to potentially lower cancer risk for both astronauts and people on Earth.

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University of California San Diego School of Medicine and Moores Cancer Center researchers report that intermittent fasting reduced breast cancer risk in obese mice.

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UC San Diego study supports launch of Phase I clinical trial to test a designer DNA agent — an antisense oligonucleotide that targets a gene called IRF4 — in patients with multiple myeloma.

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Researchers at UC San Diego School of Medicine, in collaboration with Dutch scientists, have found that certain metabolites — small molecules produced by the process of metabolism — may be predictive indicators for persons at risk for recurrent major depressive disorder.

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University of California San Diego Herbert Wertheim School of Public Health and Human Longevity Sciences researchers report that starting tobacco products, including e-cigarettes, before the age of 18 is a major risk factor for people becoming daily cigarette smokers.

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Chemicals used for vaping break down zipper-like junctions between cells in the gut, leading to chronic inflammation and potential for other health concerns.

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UC San Diego Health’s lung, heart, kidney and liver transplant programs rank at the top nationally in the latest biannual Scientific Registry of Transplant Recipients (SRTR) report. Innovative treatment and multi-disciplinary care contribute to the high rankings for one-year survival outcomes.

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UC San Diego and Ludwig Cancer Research scientists describe how a phenomenon known as “chromothripsis” breaks up chromosomes, which then reassemble in ways that ultimately promote cancer cell growth.

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In a new study, University of California San Diego School of Medicine and UC San Diego Health researchers report that the rate of firearm use by female nurses who die by suicide increased between 2014 to 2017. Published December 21, 2020 in the journal Nursing Forum, the study examined more than 2,000 nurse suicides that occurred in the United States from 2003 to 2017 and found a distinct shift from using pharmacological poisoning to firearms, beginning in 2014.

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Researchers at University of California San Diego School of Medicine will expand a statewide program to prevent driving under the influence of alcohol, cannabis and prescription drugs.

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Researchers report that hearing loss and high blood sugar are associated with poor cognitive performance among middle-aged and older Latinos.

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UC San Diego researchers report chemicals used for flavor in e-cigarette liquid negatively affect specialized proteins that support immune system.

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Researchers have identified a family of enzymes whose inhibition both protects neurons and encourages their growth, a pathway to potential new treatments for neurodegenerative diseases from Alzheimer’s to glaucoma.

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Bernard Thurman was referred to a personalized cancer therapy trial at Moores Cancer Center at UC San Diego Health, a collaboration with the La Jolla Institute for Immunology, the trial employs a patient’s immune cells — specifically tumor infiltrating lymphocytes (TIL) — to destroy cancer cells.

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UC San Diego researchers discovered that most people no longer produce the Siglec-12 protein, but some of those who do are at twice the risk for advanced cancer.

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UC San Diego researchers used brain organoids to identify two drug candidates that counteract the genetic deficiencies that cause Rett syndrome, a rare form of autism spectrum disorder.

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The California governor’s office today announced a statewide expansion to make CA Notify available to all Californians starting Thursday, December 10 in partnership with UC San Diego Health.

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University of California San Diego has been selected by the NIH to lead and administer an international seven-year, $28-million grant for HIV/AIDS clinical trials.

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UC San Diego researchers discovered that the makeup of a person’s gut microbiome is linked to their levels of active vitamin D, and revealed a new understanding of vitamin D and how it’s typically measured.

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American Association for the Advancement of Science honors the contributions of UC San Diego leaders in astrophysics, research advocacy, organic chemistry, psychiatry and geophysics.

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Triclosan, an antimicrobial found in many soaps and other household items, worsens fatty liver disease in mice fed a high-fat diet.

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While respiratory issues continue to be the most common symptom of a COVID-19 infection, new research indicates the disease could also be associated with an increased tendency of the blood to clot, leading to a higher risk of death from COVID-19.

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Researchers at UC San Diego School of Medicine and Rady Children’s Institute for Genomic Medicine have been awarded a five-year, $8.3 million grant from the National Institutes of Health to investigate the causes of spina bifida, the most common structural defect of the central nervous system.

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A team of American and Canadian researchers report that while they may feel uncomfortable, there is little empirical evidence that wearing a facemask significantly diminishes lung function, even when worn during heavy exercise.

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UC San Diego was the first university in California to connect 40,000 student health records to the electronic health record platform of its top-ranked academic medical center, UC San Diego Health. The experience has created a model for other colleges.

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Seeking to develop effective interventions, researchers at University of California San Diego School of Medicine examined the psychological and environmental factors that lead to patterns of loneliness in different age groups.

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Researchers with UC San Diego School of Medicine and Moores Cancer Center say active surveillance is safe for African American men with low-risk prostate cancer.

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Researchers determined that COVID-19 transmission risk via Halloween candies is low, even when they are handled by infected people, but handwashing and disinfecting collected sweets reduces risk even further.

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U.S. News & World Report named University of California San Diego School of Medicine a top global university and ranked the divisions of Gastroenterology and Hepatology #1 in the world for research.