Research Alert

Article title: A multimodal and integrated approach to interrogate human kidney biopsies with rigor and reproducibility: Guidelines from the Kidney Precision Medicine Project

Authors: Tarek M. El-Achkar, Michael T. Eadon, Rajasree Menon, Blue B. Lake, Tara K. Sigdel, Theodore Alexandrov, Samir Parikh, Guanshi Zhang, Dejan Dobib, Kenneth W. Dunn, Edgar A. Otto, Christopher R. Anderton, Jonas M. Carson, Jinghui Luo, Chris Park, Habib Hamidi, Jian Zhou, Paul Hoover, Andrew Schroeder, Marianinha Joanes, Evren U. Azeloglu, Rachel Sealfon, Seth Winfree, Becky Steck, Yongqun He, Vivette Denise D'Agati, Ravi Iyengar, Olga G. Troyanskaya, Laura Barisoni, Joseph Gaut, Kun Zhang, Zoltan Laszik, Brad Rovin, Pierre C. Dagher, Kumar Sharma, Minnie Sarwal, Jeffrey B. Hodgin, Charles E. Alpers, Matthias Kretzer, Sanjay Jain, For the Kidney Precision Medicine Project

From the authors: “One of the goals of the Kidney Precision Medicine Project (KPMP) is to establish rigorous pre-analytical and analytical protocols with highly standardized and controlled workflows to interrogate biopsies of [acute kidney injury] and [chronic kidney disease] patients using cutting edge OMICS and imaging technologies.” 

This study is highlighted as one of January’s "best of the best" as part of the American Physiological Society's APSselect program.

 

Journal Link: Physiological Genomics