Research Alert

Newswise — Article title: pH dependence of the Slc4a11-mediated H+ conductance is influenced by intracellular lysine residues and modified by disease-linked mutations

Authors: Bianca N. Quade, Aniko Marshall, Mark D. Parker

From the authors: “Our study has suggested a mechanism by which some mutations can result in loss of function, raises some considerations for personalization of therapeutic intervention and increases our understanding of the structure-function relationships in this unusual Slc4 protein.”

This study is highlighted as one of August’s "best of the best" as part of the American Physiological Society's APSselect program.

Journal Link: American Journal of Physiology - Cell Physiology

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American Journal of Physiology - Cell Physiology