Early Screening of Seattle-Area Pregnant Women Shows Low Infection Rate for COVID-19

Research Alert

Newswise — Screening all pregnant women who delivered at UW Medicine facilities during the height of the covid pandemic in Washington state showed that remarkably few tested positive for the virus without symptoms, a new report shows.

The study, published this week in Clinical Infectious Diseases, showed that universal testing gave a clear picture of the scope of the disease among women entering the UW Medicine hospitals to give birth, but also informed what type of precautions needed to be deployed in the individual birthing units, as well as postpartum care.

The study came to several conclusions, said Dr. Sylvia LaCourse, an Assistant professor with the University of Washington Department of Medicine, Global Health and Infectious Disease.

“UW medicine has done a remarkable job of early initiation of universal testing for COVID-19 for labor and delivery patients using a combination of on-site rapid testing, high volume centralized testing at the UW Virology lab, and outpatient drive-through screening before admission,” LaCourse said.

This meant that almost all patients had a known COVID-19 status before delivery, and informed personal protective equipment use (PPE) to ensure protection of patients and health care workers, she added.

The rate of infection was low among the mothers coming into UW Medical Center-Montlake and UW Medical Center-Northwest, with an overall positive rate of 2.7 percent. However, if mothers were symptomatic, about 20 percent of this subgroup tested positive for the virus.

“This highlights the importance of continued testing with this population,” said LaCourse. In all, the study looked at 230 mothers between March 2 and April 15 including periods before and after the initiation of universal screening.

The general infection rate among asymptomatic pregnant women was low in Seattle, as compared to early reports from New York City (which was 13-14 percent), likely due to early public health response in the region and widespread testing availability.

Despite low numbers of additional cases identified with universal screening, the continued practice should be supported for now.

“Universal screening of pregnant patients provides important surveillance information due to the representativeness of this population to the greater community, “ LaCourse said, adding that this is a generally healthy population.

LaCourse was co-first author for the study along with Dr. Alisa Kachikis, Assistant Professor in the Department of Obstetrics and Gynecology, Division of Maternal-Fetal Medicine. Drs. Kristina M. Adams Waldorf and Jane Hitti from the Department of Obstetrics and Gynecology, Division of Maternal-Fetal Medicine were co-senior authors

The study included practitioners from the UW Department of Global Health and the Fred Hutchinson Cancer Research Center. Also from the UW Medicine departments and divisions of Allergy and Infectious Diseases, Obstetrics and Gynecology, Maternal-Fetal Medicine, Laboratory Medicine, Anesthesiology and Pain Medicine, Psychiatry, Infection Prevention and Control.

This work was supported by the National Institute of Allergy and Infectious Diseases (grant numbers AI133976, AI145890, AI144938 and AI143265 to KAW and AI120793 to SML). Study data were managed using a REDCap electronic data capture tool hosted by the Institute of Translational Health Sciences at the University of Washington, which was supported by the National Center for Advancing Translational Sciences (UL1TR002319).

 

MEDIA CONTACT
Register for reporter access to contact details
CITATIONS

AI133976, AI145890, AI144938 and AI143265; Clinical Infectious Diseases

Download PDF
159163458261446_ciaa675.pdf



Filters close

Showing results

110 of 2854
Released: 11-Aug-2020 9:00 AM EDT
School spending cuts? Citizens prefer teachers and administrators to take the hit during economic crises
Binghamton University, State University of New York

With schools around the world looking into various cost-cutting measures in the midst of the COVID-10 pandemic, new research from Binghamton University, State University of New York reveals that citizens prefer teachers and administrative staff to be at the frontline of school spending cuts during times of economic crisis.

Newswise: Researchers Create Mask Filtration Effectiveness Hierarchy
11-Aug-2020 9:00 AM EDT
Researchers Create Mask Filtration Effectiveness Hierarchy
University of North Carolina School of Medicine

Infection prevention experts at the UNC Medical Center set out to gather evidence on the fitted filtration efficiency of dozens of different types of masks and mask modifications, including masks sterilized for reuse, expired masks, novel masks sourced from domestic and overseas sources, and homemade masks.

Newswise: Researchers find clues to SARS-CoV-2 infection and explore why COVID-19 impacts patients differently
Released: 11-Aug-2020 8:40 AM EDT
Researchers find clues to SARS-CoV-2 infection and explore why COVID-19 impacts patients differently
McMaster University

Previously, scientists have determined that entry of SARS-CoV-2 into cells occurs through a receptor on the cell surface, known as ACE2. But the McMaster-Waterloo team has found that the ACE2 receptor is at very low levels in human lung tissue.

Released: 10-Aug-2020 3:45 PM EDT
Vaccine to prevent tuberculosis may help limit spread of COVID-19, Missouri S&T researchers say
Missouri University of Science and Technology

A vaccine developed about a century ago to prevent tuberculosis may also help prevent the transmission of COVID-19, according to two Missouri S&T researchers who examined the spread of COVID-19 among countries that require the vaccine and those that do not.The Missouri S&T researchers analyzed COVID-19-related death and incidence rates among nations that require the BCG (Bacillus Calmette-Guerin) vaccine.

Released: 10-Aug-2020 2:50 PM EDT
Cancer care and screenings must remain a priority during COVID-19
University of Texas M. D. Anderson Cancer Center

The University of Texas MD Anderson Cancer Center is committed to safely providing patient care and cancer screenings throughout the novel coronavirus (COVID-19) pandemic.

Released: 10-Aug-2020 2:45 PM EDT
What the rest of the world can learn from South Korea's COVID-19 response
University of Colorado Denver

CU Denver researcher investigates how South Korean policy enabled the country to flatten the curve without economic disaster

Released: 10-Aug-2020 2:35 PM EDT
Tulane researchers studying rise in intimate partner violence amid COVID-19 pandemic
Tulane University

Tulane mental health experts say many of the strategies that are critical to ensuring public health are having a major impact on families experiencing intimate partner violence., also known as IPV.

Released: 10-Aug-2020 2:15 PM EDT
Mouthwashes could reduce the risk of coronavirus transmission
Ruhr-Universität Bochum

Sars-Cov-2 viruses can be inactivated using certain commercially available mouthwashes.

Newswise: Coronavirus transmission risk increases along wildlife supply chains
Released: 10-Aug-2020 2:05 PM EDT
Coronavirus transmission risk increases along wildlife supply chains
PLOS

oronaviruses were detected in a high proportion of bats and rodents in Viet Nam from 2013 to 2014, with an increasing proportion of positive samples found along the wildlife supply chain from traders to large markets to restaurants, according to a study published August 10 in the open-access journal PLOS ONE by Amanda Fine of the Wildlife Conservation Society and colleagues.


Showing results

110 of 2854

close
1.18039