Newswise — LOS ANGELES (June 2, 2021) – A UCLA team has developed a predictive model that pinpoints which populations in which neighborhoods of Los Angeles County are most at risk from COVID-19, and, by extension, which should be prioritized for vaccines.

The research – COVID-19 Medical Vulnerability Indicators: A Predictive, Local Data Model for Equity in Public Health Decision Making – will be published in the peer-reviewed International Journal of Environmental Health. With more than 10 million residents, Los Angeles County has a larger population than 41 of the states.

“The model we have includes specific resource vulnerabilities that can guide public health officials and local leaders across the nation to harness already available local data to determine which groups in which neighborhoods are most vulnerable and how to prevent new infections,” said research author Dr. Vickie Mays, UCLA Fielding School of Public Health professor of health policy and management and professor of psychology in the UCLA College.

“When the pandemic hit, we were slowed down by a lack of science and a lack of understanding of the ways in which health disparities in the lives of some of our most vulnerable populations made their risk of COVID-19 infection even greater,” Mays said. “We thought elderly and people in nursing homes were the most vulnerable, yet we found that lacking a number of social resources contributes to a greater likelihood of getting infected and in some instances leading to death as well.”

While many have been vaccinated, there are others still in neighborhoods and communities at risk of COVID-19 that need to be reached to fully re-open Los Angeles County, the authors said. The model maps the county neighborhood-by-neighborhood, based on four indicators known to increase an individual’s vulnerability to COVID-19 infection: preexisting medical conditions, barriers to accessing health care, built-environment characteristics and socioeconomic challenges that create vulnerabilities.

The research data demonstrate that neighborhoods characterized by significant clustering of racial and ethnic minorities, low-income households, and unmet social needs are still most vulnerable to COVID-19 infection, specifically areas in and around South Los Angeles and the eastern portion of the San Fernando Valley. Communities along the coast and in the northwestern part of the county, which have more white and higher-income residents, were found to be the least vulnerable.

“These same areas, along with the Palmdale-Lancaster areas, need more than just someone showing up and saying `we are here with a vaccine for you,’ “Mays said. “These are also the same communities where it will take education about the vaccine, strategies that focus on bringing households together, and incentives that bring people out even to listen to why they should take the vaccine; this is especially important in working with the Black population.”

Mays, who also directs the National Institutes of Health–funded UCLA BRITE Center for Science, Research and Policy, worked with urban planner Dr. Paul Ong, director of the UCLA Center for Neighborhood Knowledge, to develop the indicators model, along with study co-authors Chhandara Pech and Nataly Rios Gutierrez. The maps were created by Abigail Fitzgibbon. Using data from the Fielding School's UCLA Center for Health Policy Research’s California Health Interview Survey, the U.S. Census Bureau’s American Community Survey, and the California Department of Parks and Recreation, the researchers were able to determine which racial and ethnic groups in Los Angeles County were the most vulnerable, based on their geographical residence.

Although the research is focused on Los Angeles County, the methods can be duplicated across the United States, according to comments by Dr. Edward Sondik, former director of the CDC’s National Center for Health Statistics in Maryland. The commentary was published in May in the International Journal of Environmental Health, alongside the research article.

“The authors have made a major step forward and we look to our country building on this expertise,” Sondik wrote. “We look forward to research to meld this framework with the extensive ongoing COVID-19 modeling. These insights could be extremely helpful for bringing the pandemic under control.”

Methods: This project focuses on identifying neighborhoods in Los Angeles County that may be at an elevated risk of exposure and positive infection for contracting COVID-19. To achieve this, the researchers developed four different indicators of medical vulnerability: (1) pre-existing health condition, (2) barriers to accessing health care, (3) built environment risk, and (4) social vulnerability. Selections of the components used to construct the first three indicators were guided by existing research literature and input from health experts. The fourth indicator, the social vulnerability index, mirrors the Center for Disease Control’s (CDC) 2018 social vulnerability index.

Funding: This research was partially funded by the University of California Office of the President, CBCRP Grant #R00RG2606, the National Institute of Minority Health and Health Disparities (MD006923).

Data Availability Statement: All data and maps are publicly available from either — https://britecenter.org/COVID-19/ or https://knowledge.luskin.ucla.edu/covid-19-medical-vulnerability/ (accessed on 28 April 2021).

Citation(s): Ong, Paul M.; Pech, Chhandara; Gutierrez, Nataly R.; Mays, Vickie M. 2021. "COVID-19 Medical Vulnerability Indicators: A Predictive, Local Data Model for Equity in Public Health Decision Making" Int. J. Environ. Res. Public Health 18, no. 9: 4829. https://doi.org/10.3390/ijerph18094829

"Importance of Local Data and Resource Allocation for Effective Successful Public Health Interventions to Reduce COVID-19 Transmission: Commentary on COVID-19 Medical Vulnerability Indicators: A Predictive Local Data Model for Equity in Public Health Decision-Making" Int. J. Environ. Res. Public Health 18, no. 10: 5454. https://doi.org/10.3390/ijerph18105454

The UCLA Fielding School of Public Health, founded in 1961, is dedicated to enhancing the public's health by conducting innovative research, training future leaders and health professionals from diverse backgrounds, translating research into policy and practice, and serving our local communities and the communities of the nation and the world. The school has 631 students from 26 nations engaged in carrying out the vision of building healthy futures in greater Los Angeles, California, the nation and the world.

Other Link: University of California Office of the President, CBCRP Grant #R00RG2606, the National Institute of Minority Health and Health Disparities (MD006923) Journal Link: International Journal of Environmental Health