The targeted therapy combination of ibrutinib and venetoclax significantly improved progression-free survival (PFS) and achieved an overall remission rate in 82% of patients with relapsed/refractory mantle cell lymphoma (MCL), according to researchers at The University of Texas MD Anderson Cancer Center. Results from the Phase III SYMPATICO trial were presented at the 2023 American Society of Hematology (ASH) Annual Meeting.
Stem cell-based therapy improved quality of life for patients with advanced heart failure, Mayo Clinic researchers and international collaborators discovered in a late-stage multinational clinical trial.
A national, multicenter clinical trial (BMT CTN 1507) of low-dose haploidentical (half-matched) bone marrow transplant to treat severe sickle cell disease found the treatment to be safe and curative for adults with serious sickle cell-related health complications.
New research results in JNCCN are encouraging regarding the benefit of immunotherapy for treating lung cancer across racial and ethnic groups, but also reinforce need to include more Black and Hispanic people in cancer clinical trials and highlight the importance of equitable treatment delivery for closing disparities in outcomes.
Physician-investigators compared a chatbot’s probabilistic reasoning to that of human clinicians. The findings, published in JAMA Network Open, suggest that artificial intelligence could serve as useful clinical decision support tools for physicians.
Early results from a Phase I clinical trial of AT101, a new CAR T cell therapy that uses a distinct binding mechanism to target CD19, show a 100 percent complete response (CR) rate at the higher dose levels studied in the trial, according to researchers from the University of Pennsylvania Perelman School of Medicine and Penn Medicine’s Abramson Cancer Center.
UT Southwestern Medical Center is leading three multicenter clinical trials funded by the National Institute on Drug Abuse (NIDA) focused on potential treatments for methamphetamine or cocaine addiction.
Philadelphia College of Osteopathic Medicine will expand the preclinical sciences accelerated one-year master’s program in Biomedical Sciences, first launched at PCOM South Georgia, to its PCOM and PCOM Georgia campus locations beginning in 2024.
A study from Washington University School of Medicine in St. Louis and Mid-America Transplant showed that the long-standing practice of treating deceased organ donors with thyroid hormone does not help preserve heart function, may cause harm and should be discontinued.
University of Maryland School of Medicine Dean Mark T. Gladwin, MD will join prominent scientists and government health officials this week at a Symposium in Rio De Janeiro, Brazil, to discuss new treatments for sickle cell disease (SCD).
ARUP Laboratories today released the company's public comment on the FDA's proposed rule to regulate laboratory-developed tests (LDTs) as medical devices, urging the agency to withdraw the rule.
Digital Science is pleased to announce that Louisiana State University Health Shreveport (LSUHS) has chosen Dimensions Analytics and Dimensions Research Security from Digital Science’s flagship products to advance its world-class research programs.
Acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS)—two related blood diseases that disproportionally strike older adults—are notoriously difficult to treat and associated with high relapse rates.
Physician-scientists from Rutgers Cancer Institute of New Jersey and RWJBarnabas Health will present an extensive array of hematology/oncology data from their clinical research program at the 65th American Society of Hematology (ASH) Annual Meeting and Exposition, being held in San Diego, California (and virtually) from December 9-12, 2023.
HelixVM™, a virtual healthcare marketplace, showcases its ability to significantly increase physician capacity, revolutionizing the way healthcare is delivered.
George T. Grossberg, M.D., and colleagues were instrumental in developing the first and only Food and Drug Administration (FDA) approved treatment for agitation associated with Alzheimer's dementia.
Scientists have developed an ingestible device that can safely monitor vital signs like breathing and heart rate from inside humans. The tool, described November 17 in the journal Device, has the potential to provide accessible and convenient care for people at risk of opioid overdose.
The American Society for Radiation Oncology (ASTRO) issued today a clinical guideline on partial breast irradiation for patients with early-stage invasive breast cancer or ductal carcinoma in situ (DCIS).
MCRA, LLC, a leading medical device and biologics focused clinical research organization (CRO) and advisory firm integrating seven core services [U.S. and International Regulatory Affairs, Clinical Trial Operations, Reimbursement and Market Access, Healthcare Compliance, Cybersecurity, Quality Assurance, and Japan Distribution Logistics (DMAH)] is pleased to announce the hiring of Dr. Carolyn Yong and Dr. Iris Marklein as the Vice President and Senior Director, respectively, of Regulatory Affairs for Regenerative Medicine and Biologics Quality.
Investigators from the Board of Governors Regenerative Medicine Institute at Cedars-Sinai are advancing stem cell technology to treat degenerative diseases of the eye.
This year, the American Association of Critical-Care Nurses,awarded three AACN Impact Research Grants up to $50,000 each and the AACN-Sigma Critical Care Grant with up to $10,000 in funding. Since launching the grants program in 2011, AACN has awarded more than $1.4 million in funding and 33 Impact Research Grants.
Investigators from the Antiphospholipid Syndrome Alliance for Clinical Trials and International Networking (APS ACTION) presented new research findings in antiphospholipid syndrome (APS) at the American College of Rheumatology (ACR) Convergence 2023, the ACR’s annual meeting.
An international clinical trial led by physician Jeffrey L. Carson, distinguished professor of medicine at Rutgers Robert Wood Johnson Medical School, found that a liberal blood transfusion given to patients who have had a heart attack and have anemia may reduce the risk of a reoccurrence and improve survival rates.
The Speech Accessibility Project is now recruiting U.S. adults with Down syndrome. The project aims to make voice recognition technology more useful for people with diverse speech patterns and different disabilities.
The University of Texas MD Anderson Cancer Center today announced the launch of its Institute for Data Science in Oncology (IDSO), which integrates the most advanced computational and data science approaches with the institution’s extensive scientific and clinical expertise to significantly improve patient’s lives by transforming cancer care and research.
UNC Health is the only academic healthcare system in North Carolina and the South participating in the randomized trial, which aims to assess the safety and efficacy of a combination immunotherapy for newly diagnosed glioblastoma patients.
MD Anderson and Jazz Pharmaceuticals announced a five-year strategic research collaboration agreement to evaluate zanidatamab, Jazz’s investigational HER2-targeted bispecific antibody, in multiple HER2-expressing cancers.
The results of numerous high-impact clinical trials that could affect kidney-related medical care will be presented in-person at ASN Kidney Week 2023 November 1–November 5.
Rakuten Medical, Inc., a global biotechnology company developing and commercializing precision, cell targeting therapies based on its proprietary Alluminox™ platform, today announced that the Company will present at the 14th Annual Jefferies London Healthcare Conference being held in London, UK, on November 14-16, 2023.
In an invited commentary, Kathleen Mulvaney, assistant professor with the Fralin Biomedical Research Institute at VTC, talks about the potential of a new drug that has shown early promise in clinical trials for solid tumors by killing cancer cells that lack specific tumor suppressor genes.
Georgia Trend magazine recognized Aoun, 27, as a member of the 2023 class of 40 Under 40 and placed his photo on the cover of the magazine as the youngest to receive this year’s recognition.
Southwest Florida residents will soon have greater access to top-tier cancer care and clinical trials when Sylvester Comprehensive Cancer Center opens its Naples office on Nov. 1.
A new drug developed by professors from the School of Pharmacy and Pharmaceutical Sciences at Binghamton University, State University of New York has received FDA approval for the treatment of patients with Duchenne muscular dystrophy, a common genetic disease that mostly affects young boys.
A researcher from the Case Western Reserve University Frances Payne Bolton School of Nursing has been awarded a $3.5 million federal grant for research to improve sleep health and glucose management in young adults with type 1 diabetes. Positive findings could lead to adding the intervention in current care protocols.
Researchers at Baylor College of Medicine have identified a small molecule named 5D4 that can suppress the growth of breast and ovarian cancers in animal models.
Cabozantinib, which targets tumor cell growth and tumor blood vessel growth, sharply improved progression-free survival over placebo in patients with extra-pancreatic and pancreatic neuroendocrine tumors
Belzutifan significantly reduced the risk of progression of clear cell renal cell carcinoma (ccRCC), the most common type of kidney cancer, in patients previously treated with immune checkpoint inhibitors and anti-angiogenic therapies compared with everolimus in a phase 3 clinical trial.
Stimulating muscle fibers with magnets causes them to grow in the same direction, aligning muscle cells within tissue, Massachusetts Institute of Technology (MIT) and Boston University investigators report October 20 in the journal Device.
New research reveals that the nation’s most widely prescribed type of sedative may be less effective than clinicians and scientists have been led to believe, based on publications in medical journals.
A potential treatment for the world’s leading cause of kidney failure in children needing dialysis has been discovered by an international team of scientists. The University of Bristol-led breakthrough is published today [19 October] in Med.
The American Thoracic Society is accepting scientific abstracts and case report submissions for presentation at the ATS 2024 International Conference in San Diego, May 17-22. Submissions on all aspects of respiratory disease, critical care medicine and sleep medicine will be considered and are due no later than Wednesday, Nov. 1, 2023, at 5 p.m. ET.
Walgreens and the Cardiovascular Research Foundation (CRF) today announced a collaboration to drive forward the PREVUE-VALVE study, a groundbreaking population-based clinical trial that aims to quantify the prevalence of valvular heart disease (VHD) among older Americans and pave the way for the development of new therapies and tools for VHD detection and diagnosis.
The Gore RELIEF Clinical Study is evaluating the safety and efficacy of transcatheter closure of patent foramen ovale (PFO) with the GORE® CARDIOFORM Septal Occluder for the relief of migraine headaches.
Chronic inflammation of the skin, or Hidradenitis Suppurativa (HS), disproportionately affects women and people of color. It can be debilitating, negatively impacting suffers’ quality of life, physical function, work productivity, and the social and emotional wellbeing.